Kai Kaarniranta
Professor
Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences
kai.kaarniranta@uef.fi
Research groups
Projects
Publications
445/445 items-
A New Generation of Gene Therapies as the Future of Wet AMD Treatment
Blasiak, Janusz; Pawlowska, Elzbieta; Ciupińska, Justyna; Derwich, Marcin; Szczepanska, Joanna; Kaarniranta, Kai. 2024. International journal of molecular sciences. 25: A2 Review article, Literature review, Systematic review -
Acta Ophthalmologica 100 years-Overview of selected articles during Acta Ophthalmologica history
Kaarniranta, Kai; Pawlikowska-Lagod, Katarzyna; Jääskeläinen, Juha E; Grzybowski, Andrzej E. 2024. Acta ophthalmologica. 102: 367-373 B1 Non-refereed journal articles -
Acta Ophthalmologica stands on top level after 100 years
Kaarniranta, Kai; Stefánsson, Einar. 2024. Acta ophthalmologica. [Epub ahead of print 10 September 2024]: 1-3 B1 Non-refereed journal articles -
Analysis of prognostic and predictive factors in neovascular age-related macular degeneration Kuopio cohort
Heloterä, Hanna; Siintamo, Leea; Kivinen, Niko; Abrahamsson, Nicholas; Aaltonen, Vesa; Kaarniranta, Kai. 2024. Acta ophthalmologica. 102: 703-713 A1 Journal article (refereed), original research -
Association of hearing, vision, and dual sensory impairment and risk of Alzheimer’s disease: a nested case-control study
Rajamaki, Blair; Hokkinen, Kaisa; Dietz, Aarno; Kaarniranta, Kai; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2024. Bmc geriatrics. 24: . 929 A1 Journal article (refereed), original research -
Autophagy in drusen biogenesis secondary to age-related macular degeneration
Hyttinen, Juha M T; Koskela, Ali; Blasiak, Janusz; Kaarniranta, Kai. 2024. Acta ophthalmologica. 102: 759-772 A2 Review article, Literature review, Systematic review -
Exploring the Association Between Visual Field Testing and CERAD Neuropsychological Battery in Idiopathic Normal Pressure Hydrocephalus Patients
Kemiläinen, Benjam; Tiainen, Sonja; Rauramaa, Tuomas; Luikku, Antti J; Herukka, Sanna-Kaisa; Koivisto, Anne; Hiltunen, Mikko; Verdooner, Steven; Johnson, Ken; Chambers, Mieko; Kaarniranta, Kai; Leinonen, Ville. 2024. Journal of Alzheimer's disease. 100: 247-260 A1 Journal article (refereed), original research -
Konsensusehdotukset dosentin arvon myöntämiseen liittyvistä käytänteistä ja näkökulmista
Axelin, Anna; Heikinheimo, Markku; Heistaro, Sami; Kaarniranta, Kai; Kähönen, Mika; Lehenkari, Petri; Parkkila, Seppo; Rautalahti, Matti; Riipinen, Pirkko; Rämet, Mika; Saharinen, Pipsa; Toppari, Jorma; Vainionpää, Anne. 2024. Duodecim. 140: 77-82 D1 Article in a trade journal -
Metformin Alleviates Inflammation and Induces Mitophagy in Human Retinal Pigment Epithelium Cells Suffering from Mitochondrial Damage
Toppila, Maija; Ranta-aho, Sofia; Kaarniranta, Kai; Hytti, Maria; Kauppinen, Anu. 2024. Cells. 13: A1 Journal article (refereed), original research -
Oxidative Stress and Inflammation-Related mRNAs Are Elevated in Serum of a Finnish Wet AMD Cohort
Liukkonen, Mikko; Heloterä, Hanna; Siintamo, Leea; Ghimire, Bishwa; Mattila, Pirkko; Kivinen, Niko; Kostanek, Joanna; Watala, Cezary; Hytti, Maria; Hyttinen, Juha; Koskela, Ali; Blasiak, Janusz; Kaarniranta, Kai. 2024. Investigative ophthalmology and visual science. 65: A1 Journal article (refereed), original research -
Oxidative Stress, Persistent Inflammation and Blood Coagulation Alterations in Serum Proteome of Patients with Neovascular Age-Related Macular Degeneration
Winiarczyk, Mateusz; Thiede, Bernd; Utheim, Tor Paaske; Kaarniranta, Kai; Winiarczyk, Dagmara; Michalak, Katarzyna; Mackiewicz, Jerzy. 2024. Life. 14: A1 Journal article (refereed), original research -
PGC‐1α regulates the interplay between oxidative stress, senescence and autophagy in the ageing retina important in age‐related macular degeneration
Gurubaran, Iswariyaraja Sridevi; Watala, Cezary; Kostanek, Joanna; Szczepanska, Joanna; Pawlowska, Elzbieta; Kaarniranta, Kai; Blasiak, Janusz. 2024. Journal of cellular and molecular medicine. 28: 1-13 A1 Journal article (refereed), original research -
Silmänpohjan ikärappeuman esiintyminen ja hoitomahdollisuudet
Purola, Petri; Kaarniranta, Kai; Uusitalo, Hannu. 2024. Duodecim. 140: 215-222 A2 Review article, Literature review, Systematic review -
The AKT2/SIRT5/TFEB pathway as a potential therapeutic target in non-neovascular AMD
Ghosh, Sayan; Sharma, Ruchi; Bammidi, Sridhar; Koontz, Victoria; Nemani, Mihir; Yazdankhah, Meysam; Kedziora, Katarzyna M; Stolz, Donna Beer; Wallace, Callen T; Yu-Wei, Cheng; Franks, Jonathan; Bose, Devika; Shang, Peng; Ambrosino, Helena M; Dutton, James R; Geng, Zhaohui; Montford, Jair; Ryu, Jiwon; Rajasundaram, Dhivyaa; Hose, Stacey; Sahel, José Alain; Puertollano, Rosa; Finkel, Toren; Zigler, J Samuel; Sergeev, Yuri; Watkins, Simon C; Goetzman, Eric S; Ferrington, Deborah A; Flores-Bellver, . 2024. Nature communications. 15: . 6150 A1 Journal article (refereed), original research -
The VL Nordic Congress of Ophthalmology 2024
Kaarniranta, Kai; Stefánsson, Einar. 2024. Acta ophthalmologica. 102: 504-505 B1 Non-refereed journal articles -
The incidence and prevalence of diabetic macular edema and proliferative diabetic retinopathy, their progression to visual impairment and patterns in their intravitreal treatment in the Finnish population
Heloterä, Hanna; Arffman, Martti; Sund, Reijo; Keskimäki, Ilmo; Kaarniranta, Kai. 2024. Acta ophthalmologica. 102: 643-652 A1 Journal article (refereed), original research -
Tissue fibroblasts are versatile immune regulators: An evaluation of their impact on the aging process
Salminen, Antero; Kaarniranta, Kai; Kauppinen, Anu. 2024. Ageing research reviews. 97: A2 Review article, Literature review, Systematic review -
VEGF and ELAVL1/HuR protein levels are increased in dry and wet AMD patients. A New Tile in the Pathophysiologic Mechanisms Underlying RPE Degeneration?
Bresciani, Giorgia; Manai, Federico; Felszeghy, Szabolcs; Smedowski, Adrian; Kaarniranta, Kai; Amadio, Marialaura. 2024. Pharmacological research. 208: A1 Journal article (refereed), original research -
Ventriculoperitoneal shunt patients and glaucoma: a cohort analysis of the NPH registry
Kemiläinen, Benjam; Kaarniranta, Kai; Leinonen, Ville. 2024. Fluids and barriers of the cns. 21: . 54 A1 Journal article (refereed), original research -
Acta Ophthalmologica for 100 years
Kaarniranta, Kai; Stefansson, Einar. 2023. Acta ophthalmologica. 101: 7 B1 Non-refereed journal articles -
Association of APOE Haplotypes With Common Age-Related Ocular Diseases in 412,171 Individuals
Liuska, Perttu J; Rämö, Joel T; Lemmelä, Susanna; Kaarniranta, Kai; Uusitalo, Hannu; Lahtela, Elisa; Daly, Mark J; Harju, Mika; Palotie, Aarno; Turunen, Joni A. 2023. Investigative ophthalmology and visual science. 64: A1 Journal article (refereed), original research -
Cis-urocanic acid improves cell viability and suppresses inflammasome activation in human retinal pigment epithelial cells
Korhonen, Eveliina; Piippo, Niina; Hytti, Maria; Kaarniranta, Kai; Kauppinen, Anu. 2023. Biochemical pharmacology. 216: A1 Journal article (refereed), original research -
Comparison of barrier properties of outer blood-retinal barrier models - Human stem cell-based models as a novel tool for ocular drug discovery
Hellinen, Laura; Hongisto, Heidi; Ramsay, Eva; Kaarniranta, Kai; Vellonen, Kati-Sisko; Skottman, Heli; Ruponen, Marika. 2023. European journal of pharmaceutics and biopharmaceutics. 184: 181-188 A1 Journal article (refereed), original research -
Crosstalk of protein clearance, inflammasome, and Ca2+ channels in retinal pigment epithelium derived from age-related macular degeneration patients
Karema-Jokinen, Viivi; Koskela, Ali; Hytti, Maria; Hongisto, Heidi; Viheriälä, Taina; Liukkonen, Mikko; Torsti, Tommi; Skottman, Heli; Kauppinen, Anu; Nymark, Soile; Kaarniranta, Kai. 2023. Journal of biological chemistry. 299: A1 Journal article (refereed), original research -
Epigallocatechin-3-Gallate, an Active Green Tea Component to Support Anti-VEGFA Therapy in Wet Age-Related Macular Degeneration
Blasiak, Janusz; Chojnacki, Jan; Szczepanska, Joanna; Fila, Michal; Chojnacki, Cezary; Kaarniranta, Kai; Pawlowska, Elzbieta. 2023. Nutrients. 15: A2 Review article, Literature review, Systematic review -
Extracellular vesicles in degenerative retinal diseases: A new therapeutic paradigm
Manai, Federico; Smedowski, Adrian; Kaarniranta, Kai; Comincini, Sergio; Amadio, Marialaura. 2023. Journal of controlled release. 2024; 365: 448-468 A2 Review article, Literature review, Systematic review -
FinnGen provides genetic insights from a well-phenotyped isolated population
Kurki, Mitja I.; Karjalainen, Juha; Palta, Priit; Sipilä, Timo P.; Kristiansson, Kati; Donner, Kati M.; Reeve, Mary P.; Laivuori, Hannele; Aavikko, Mervi; Kaunisto, Mari A.; Loukola, Anu; Lahtela, Elisa; Mattsson, Hannele; Laiho, Päivi; Della Briotta Parolo, Pietro; Lehisto, Arto A.; Kanai, Masahiro; Mars, Nina; Rämö, Joel; Kiiskinen, Tuomo; Heyne, Henrike O.; Veerapen, Kumar; Rüeger, Sina; Lemmelä, Susanna; Zhou, Wei; Ruotsalainen, Sanni; Pärn, Kalle; Hiekkalinna, Tero; Koskelainen, Sami; Paaja. 2023. Nature. 613: 508-518 A1 Journal article (refereed), original research -
Geographic atrophy ends Acta Ophthalmologica centennial
Kaarniranta, Kai; Stefánsson, Einar. 2023. Acta ophthalmologica. 101: 837-838 B1 Non-refereed journal articles -
Lysosomes in retinal health and disease
Boya, Patricia; Kaarniranta, Kai; Handa, James T; Sinha, Debasish. 2023. Trends in neurosciences. 46: 1067-1082 A2 Review article, Literature review, Systematic review -
Non-Coding RNAs Regulating Mitochondrial Functions and the Oxidative Stress Response as Putative Targets against Age-Related Macular Degeneration (AMD)
Hyttinen, Juha MT; Blasiak, Janusz; Kaarniranta, Kai. 2023. International journal of molecular sciences. 24: A2 Review article, Literature review, Systematic review -
Overlap of Genetic Loci for Central Serous Chorioretinopathy With Age-Related Macular Degeneration
Rämö, Joel T.; Abner, Erik; van Dijk, Elon HC; Wang, Xin; Brinks, Joost; Nikopensius, Tiit; Nõukas, Margit; Marjonen, Heidi; Silander, Kaisa; Jukarainen, Sakari; Kiiskinen, Tuomo; Choi, Seung Hoan; Kajanne, Risto; Mehtonen, Juha; Palta, Priit; Lubitz, Steven A.; Kaarniranta, Kai; Sobrin, Lucia; Kurki, Mitja; Yzer, Suzanne; Ellinor, Patrick T; Esko, Tõnu; Daly, Mark J; den Hollander, Anneke I; Palotie, Aarno; Turunen, Joni A.; Boon, Camiel JF; Rossin, Elizabeth J; for the FinnGen Study; for the E. 2023. JAMA ophthalmology. 141: 449-457 A1 Journal article (refereed), original research -
Oxidative Stress and Cellular Protein Accumulation Are Present in Keratoconus, Macular Corneal Dystrophy, and Fuchs Endothelial Corneal Dystrophy
Vottonen, Linda; Koskela, Ali; Felszeghy, Szabolcs; Wylegala, Adam; Kryszan, Katarzyna; Gurubaran, Iswariyaraja Sridevi; Kaarniranta, Kai; Wylegala, Edward. 2023. Journal of clinical medicine. 12: A1 Journal article (refereed), original research -
The Prolyl Oligopeptidase Inhibitor KYP-2047 Is Cytoprotective and Anti-Inflammatory in Human Retinal Pigment Epithelial Cells with Defective Proteasomal Clearance
Toppila, Maija; Hytti, Maria; Korhonen, Eveliina; Ranta-aho, Sofia; Harju, Niina; Forsberg, Markus M.; Kaarniranta, Kai; Jalkanen, Aaro; Kauppinen, Anu. 2023. Antioxidants. 12: A1 Journal article (refereed), original research -
A Linkage between Angiogenesis and Inflammation in Neovascular Age-Related Macular Degeneration
Heloterä, Hanna; Kaarniranta, Kai. 2022. Cells. 11: A2 Review article, Literature review, Systematic review -
Acta Ophthalmologica 2021
Kaarniranta, Kai; Stefánsson, Einar. 2022. Acta ophthalmologica. 100: 483-485 B1 Non-refereed journal articles -
Ajokorttitodistusten näkövaatimukset
Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 680. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Angioid streak
Kaarniranta, Kai; Uusitalo-Järvinen, Hannele. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 272-273. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Autophagy in age-related macular degeneration
Kaarniranta, Kai; Blasiak, Janusz; Liton, Paloma; Boulton, Michael; Klionsky, Daniel J.; Sinha, Debasish. 2022. Autophagy. 2023; 19: 388-400 A2 Review article, Literature review, Systematic review -
Bestin tauti
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 265. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Brolusitsumabi
Kaarniranta, Kai; Kajander, Maria. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 773. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Computer-based Eye-tracking Analysis of King-Devick Test Differentiates Persons With Idiopathic Normal Pressure Hydrocephalus From Cognitively Unimpaired
Lehtola, Juha-Matti; Kärkkäinen, Virve; Andberg, Sami; Hannonen, Sanna; Rusanen, Minna; Saari, Toni; Korhonen, Ville; Hokkanen, Laura; Hallikainen, Merja; Hänninen, Tuomo; Kaarniranta, Kai; Bednarik, Roman; Leinonen, Ville; Koivisto, Anne M. 2022. Alzheimer disease and associated disorders. 36: 340-346 A1 Journal article (refereed), original research -
Epidemia-ajan erityistoimet silmäpotilailla
Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 67-68. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Epidemia-ajan kiireellinen ja kiireetön hoito silmätaudeilla
Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 59-66. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Epoxomicin, a Selective Proteasome Inhibitor, Activates AIM2 Inflammasome in Human Retinal Pigment Epithelium Cells
Sridevi Gurubaran, Iswariyaraja; Hytti, Maria; Kaarniranta, Kai; Kauppinen, Anu. 2022. Antioxidants. 11: A1 Journal article (refereed), original research -
Etukammionäytteen ja lasiaisnäytteen otto
Kaarniranta, Kai; Marttila, Liisa; Seppänen, Matti. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 631. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Fluoreseiiniangiografia (FAG)
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 579-580. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Fotodynaaminen hoito (PDT)
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 657. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Hormetic Heat Shock Enhances Autophagy through HSF1 in Retinal Pigment Epithelium Cells
Amirkavei, Mooud; Plastino, Flavia; Kvanta, Anders; Kaarniranta, Kai; André, Helder; Koskelainen, Ari. 2022. Cells. 11: A1 Journal article (refereed), original research -
Hydroquinone increases risk for retinal pigment epithelial (RPE) cell degeneration
Bhattarai, Niina; Hytti, Maria; Mysore, Yashavanthi; Kaarniranta, Kai; Kauppinen, Anu. 2022. Acta ophthalmologica abstract -
Hydroquinone predisposes for retinal pigment epithelial (RPE) cell degeneration in inflammatory conditions
Bhattarai, Niina; Hytti, Maria; Reinisalo, Mika; Kaarniranta, Kai; Mysore, Yashavanthi; Kauppinen, Anu. 2022. Immunologic research. 70: 678-687 A1 Journal article (refereed), original research -
Incidence of cataract surgeries in relation to diagnosis of Parkinson's disease
Lampela, Pasi; Tolppanen, Anna-Maija; Kaarniranta, Kai; Hokkinen, Kaisa; Hartikainen, Sirpa. 2022. Archives of gerontology and geriatrics. 2023; 104: A1 Journal article (refereed), original research -
Indosyaaniinivihreä
Kivinen, Niko; Kaarniranta, Kai; Kajander, Maria. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 766-767. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Interplay between aging and other factors of the pathogenesis of age-related macular degeneration
Blasiak, Janusz; Sobczuk, Piotr; Pawlowska, Elzbieta; Kaarniranta, Kai. 2022. Ageing research reviews. 81: A2 Review article, Literature review, Systematic review -
Ketotifeeni
Marttila, Liisa; Kivinen, Niko; Kaarniranta, Kai; Seppänen, Matti; Kaustiala, Klaudia. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 755. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Lasiaisinjektion toteutus
Kaarniranta, Kai; Seppänen, Matti. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 704-. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Leikkauksenjälkeinen silmämunan sisäosien yleistulehdus
Kaarniranta, Kai; Marttila, Liisa; Seppänen, Matti. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 211-215. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Microglia–Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse Model
Boyce, Maeve; Xin, Ying; Chowdhury, Olivia; Shang, Peng; Liu, Haitao; Koontz, Victoria; Strizhakova, Anastasia; Nemani, Mihir; Hose, Stacey; Zigler, J. Samuel; Campbell, Matthew; Sinha, Debasish; Handa, James T.; Kaarniranta, Kai; Qian, Jiang; Ghosh, Sayan. 2022. Cells. 11: A1 Journal article (refereed), original research -
Mikrobinäytteen otto silmästä
Kaarniranta, Kai, Setälä, Niko. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 627-629. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Myooppinen degeneraatio
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 264-265. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Nature-Inspired Hybrids (NIH) Improve Proteostasis by Activating Nrf2-Mediated Protective Pathways in Retinal Pigment Epithelial Cells
Koskela, Ali; Manai, Federico; Basagni, Filippo; Liukkonen, Mikko; Rosini, Michela; Govoni, Stefano; Monte, Massimo Dal; Smedowski, Adrian; Kaarniranta, Kai; Amadio, Marialaura. 2022. Antioxidants. 11: . 1385 A1 Journal article (refereed), original research -
Optic pit -makulopatia
Kaarniranta, Kai; Seppänen, Matti. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 385-386. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Optinen valokerroskuvaus (OCT)
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 583-594. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Photoaging: UV radiation-induced inflammation and immunosuppression accelerate the aging process in the skin
Salminen, Antero; Kaarniranta, Kai; Kauppinen, Anu. 2022. Inflammation research. 71: 817-831 A2 Review article, Literature review, Systematic review -
Polyyppimainen suonikalvoston rappeuma
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 260. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Ravistellun vauvan oireyhtymä
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 523-524. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Retraction: Hellinen et al. Drug Flux across RPE Cell Models: The Hunt for an Appropriate Outer Blood–Retinal Barrier Model for Use in Early Drug Discovery. Pharmaceutics 2020, 12, 176
Hellinen, Laura; Hongisto, Heidi; Ramsay, Eva; Kaarniranta, Kai; Vellonen, Kati-Sisko; Skottman, Heli; Ruponen, Marika. 2022. Pharmaceutics. 14: 595 B1 Non-refereed journal articles -
Secretory autophagy: a turn key for understanding AMD pathology and developing new therapeutic targets?
Blasiak, Janusz; Kaarniranta, Kai. 2022. Expert opinion on therapeutic targets. 26: 883-895 A2 Review article, Literature review, Systematic review -
Shortening of Saccades as a Possible Easy-to-Use Biomarker to Detect Risk of Alzheimer’s Disease
Hannonen, Sanna; Andberg, Sami; Kärkkäinen, Virve; Rusanen, Minna; Lehtola, Juha-Matti; Saari, Toni; Korhonen, Ville; Hokkanen, Laura; Hallikainen, Merja; Hänninen, Tuomo; Leinonen, Ville; Kaarniranta, Kai; Bednarik, Roman; Koivisto, Anne M.. 2022. Journal of Alzheimer's disease. 88: 609-618 A1 Journal article (refereed), original research -
Siklosporiini
Seppänen, Matti; Kaarniranta, Kai; Kajander, Maria. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 777-778. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Silmälääkkeet ja niiden vaikutukset
Hautala, Nina; Kaarniranta, Kai; Uusitalo, Hannu. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 699-702. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Silmänpohjan ikärappeumat
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 257-259. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Silmänvärve (nystagmus)
Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 395. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Silmätautien käsikirja
Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu. 2022. . 3., uudistettu painos. Kustannus Oy Duodecim D6 Edited professional book -
Sisäsyntyisen silmämunan sisäosien tulehdus
Marttila, Liisa; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 215-216. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Stargardtin tauti/Fundus flavimaculatus
Kaarniranta, Kai; Seppänen, Matti. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 266-267. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Telangiekstasiat
Kaarniranta, Kai; Setälä, Niko. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 273-274. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
The Effect of Dietary Supplementations on Delaying the Progression of Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis
Csader, Susanne; Korhonen, Sonja; Kaarniranta, Kai; Schwab, Ursula. 2022. Nutrients. 14: A2 Review article, Literature review, Systematic review -
Topical treatment of diabetic macular edema using dexamethasone ophthalmic suspension: A randomized, double‐masked, vehicle‐controlled study
Stefansson, Einar; Loftsson, Thorstein; Larsen, Michael; Papp, András; Kaarniranta, Kai; Munk, Marion R.; Dugel, Pravin; Tadayoni, Ramin. 2022. Acta ophthalmologica. 2023; 101: 22-33 A1 Journal article (refereed), original research -
Valsalva retinopatia
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 276. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Verkkokalvo-oksimetri
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 583. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Verkkokalvohalkio
Kaarniranta, Kai; Marttila, Liisa. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 281-282. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Verkkokalvon angiomaattinen proliferaatio
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 261-262. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Verkkokalvon keskeinen nesteirtauma
Kivinen, Niko; Kaarniranta, Kai; Seppänen Matti. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 262-264. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Verkkokalvon makroaneurysma
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 274-275. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Verkkokalvon reunaosien rappeumat
Marttila, Liisa, Kaarniranta, Kai . Teoksessa: Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2022. Silmätautien käsikirja. s. 282-284. Kustannus Oy Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Visual impairment due to age‐related macular degeneration during 40 years in Finland and the impact of novel therapies
Purola, Petri; Kaarniranta, Kai; Ojamo, Matti; Gissler, Mika; Uusitalo, Hannu. 2022. Acta ophthalmologica. 2023; 101: 57-64 A1 Journal article (refereed), original research -
Antimycin A-induced mitochondrial dysfunction regulates inflammasome signaling in human retinal pigment epithelial cells
Korhonen, Eveliina; Hytti, Maria; Piippo, Niina; Kaarniranta, Kai; Kauppinen, Anu. 2021. Experimental eye research. 209: 108687 A1 Journal article (refereed), original research -
Association of the MYOC p.(Gln368Ter) Variant With Glaucoma in a Finnish Population
Liuska, PJ; Lemmelä, S; Havulinna, AS; Kaarniranta, K; Uusitalo, H; Laivuori, H; Kiiskinen, T; Daly, MJ; Palotie, A; Turunen, JA. 2021. JAMA ophthalmology. 139: 762-768 A1 Journal article (refereed), original research -
Differential Expression of Inflammasome-Related Genes in Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells with or without History of Age-Related Macular Degeneration
Hytti, Maria; Korhonen, Eveliina; Hongisto, Heidi; Kaarniranta, Kai; Skottman, Heli; Kauppinen, Anu. 2021. International journal of molecular sciences. 22: 6800 A1 Journal article (refereed), original research -
Dysregulated Tear Film Proteins in Macular Edema Due to the Neovascular Age-Related Macular Degeneration Are Involved in the Regulation of Protein Clearance, Inflammation, and Neovascularization
Winiarczyk, Mateusz; Winiarczyk, Dagmara; Michalak, Katarzyna; Kaarniranta, Kai; Adaszek, Lukasz; Winiarczyk, Stanislaw; Mackiewicz, Jerzy. 2021. Journal of clinical medicine. 10: 3060 A1 Journal article (refereed), original research -
Effect of cataract surgery on wet age-related macular degeneration activity
Karesvuo, Petteri; Elbaz, Uri; Achiron, Asaf; Hecht, Idan; Kaarniranta, Kai; Tuuminen, Raimo. 2021. Acta ophthalmologica. 2022; 100: e262-e269 A1 Journal article (refereed), original research -
Effects of Resvega on Inflammasome Activation in Conjunction with Dysfunctional Intracellular Clearance in Retinal Pigment Epithelial (RPE) Cells
Bhattarai, Niina; Piippo, Niina; Ranta-aho, Sofia; Mysore, Yashavanthi; Kaarniranta, Kai; Kauppinen, Anu. 2021. Antioxidants. 10: 67 A1 Journal article (refereed), original research -
Epithelial-Mesenchymal Transition and Senescence in the Retinal Pigment Epithelium of NFE2L2/PGC-1α Double Knock-Out Mice
Blasiak, Janusz; Koskela, Ali; Pawlowska, Elzbieta; Liukkonen, Mikko; Ruuth, Johanna; Toropainen, Elisa; Hyttinen, Juha MT; Viiri, Johanna; Eriksson, John E.; Xu, Heping; Chen, Mei; Felszeghy, Szabolcs; Kaarniranta, Kai. 2021. International journal of molecular sciences. 22: 1684 A1 Journal article (refereed), original research -
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Klionsky, Daniel J; Abdel-Aziz, Amal Kamal; Abdelfatah, Sara; Abdellatif, Mahmoud; Abdoli, Asghar; Abel, Steffen; Abeliovich, Hagai; Abildgaard, Marie H; Abudu, Yakubu Princely; Acevedo-Arozena, Abraham; Adamopoulos, Iannis E; Adeli, Khosrow; Adolph, Timon E; Adornetto, Annagrazia; Aflaki, Elma; Agam, Galila; Agarwal, Anupam; Aggarwal, Bharat B; Agnello, Maria; Agostinis, Patrizia et al. [Incl. Haapasalo, Annakaisa; Leskelä, Stina; Kaarniranta, Kai; Kauppinen, Anu; Koskela, Ali]. 2021. Autophagy. 17: 1-382 A2 Review article, Literature review, Systematic review -
Hydroquinone Induces NLRP3-Independent IL-18 Release from ARPE-19 Cells
Bhattarai, Niina; Korhonen, Eveliina; Mysore, Yashavanthi; Kaarniranta, Kai; Kauppinen, Anu. 2021. Cells. 10: 1405 A1 Journal article (refereed), original research -
Hypoxia/ischemia impairs CD33 (Siglec-3)/TREM2 signaling: Potential role in Alzheimer's pathogenesis
Salminen, Antero; Kaarniranta, Kai; Kauppinen, Anu. 2021. Neurochemistry international. 150: 105186 A2 Review article, Literature review, Systematic review -
Incidence of cataract surgeries in people with and without Alzheimer's disease
Hokkinen, K; Kaarniranta, K; Jämsen, E; Lampela, P; Hartikainen, S; Tolppanen, AM. 2021. Acta ophthalmologica. 2022; 100: 68-73 A1 Journal article (refereed), original research -
Inhibition of prolyl oligopeptidase: A promising pathway to prevent the progression of age-related macular degeneration
Hellinen, Laura; Koskela, Ali; Vattulainen, Elina; Liukkonen, Mikko; Wegler, Christine; Treyer, Andrea; Handin, Niklas; Svensson, Richard; Myöhänen, Timo; Poso, Antti; Kaarniranta, Kai; Artursson, Per; Urtti, Arto. 2021. Biomedicine and pharmacotherapy. 2022; 146: 112501 A1 Journal article (refereed), original research -
Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases
Salminen, Antero; Kaarniranta, Kai; Kauppinen, Anu. 2021. Inflammation research. 70: 1043-1061 A2 Review article, Literature review, Systematic review -
Lasiaisinjektiot mullistivat silmänpohjan kostean ikärappeuman hoidon
Kivinen, Niko; Kaarniranta, Kai. 2021. Lääkärilehti. 76: 2055-2058 A2 Review article, Literature review, Systematic review -
MicroRNAs in the regulation of autophagy and their possible use in age-related macular degeneration therapy
Hyttinen, Juha M T; Blasiak, Janusz; Felszeghy, Szabolcs; Kaarniranta, Kai. 2021. Ageing research reviews. 67: 101260 A2 Review article, Literature review, Systematic review -
Oxidative Stress and Mitochondrial Damage in Dry Age-Related Macular Degeneration Like NFE2L2/PGC-1[alpha] -/- Mouse Model Evoke Complement Component C5a Independent of C3
Sridevi Gurubaran, Iswariyaraja; Heloterä, Hanna; Marry, Stephen; Koskela, Ali; Hyttinen, Juha MT; Paterno, Jussi J; Urtti, Arto; Chen, Mei; Xu, Heping; Kauppinen, Anu; Kaarniranta, Kai. 2021. Biology. 10: 622 A1 Journal article (refereed), original research -
Pinosylvin Extract Retinari™ Sustains Electrophysiological Function, Prevents Thinning of Retina, and Enhances Cellular Response to Oxidative Stress in NFE2L2 Knockout Mice
Tamminen, Toni; Koskela, Ali; Toropainen, Elisa; Gurubaran, Iswariyaraja Sridevi; Winiarczyk, Mateusz; Liukkonen, Mikko; Paterno, Jussi J; Lackman, Petri; Sadeghi, Amir; Viiri, Johanna; Hyttinen, Juha MT; Koskelainen, Ari; Kaarniranta, Kai. 2021. Oxidative medicine and cellular longevity. 2021: A1 Journal article (refereed), original research -
Potential of Long Non-Coding RNAs in Age-Related Macular Degeneration
Blasiak, Janusz; Hyttinen, Juha M. T.; Szczepanska, Joanna; Pawlowska, Elzbieta; Kaarniranta, Kai. 2021. International journal of molecular sciences. 22: 9178 A2 Review article, Literature review, Systematic review -
Potential of Telomerase in Age-Related Macular Degeneration-Involvement of Senescence, DNA Damage Response and Autophagy and a Key Role of PGC-1α
Blasiak, J; Szczepanska, J; Fila, M; Pawlowska, E; Kaarniranta, K. 2021. International journal of molecular sciences. 22: 7194 A2 Review article, Literature review, Systematic review -
Serum Levels of Plasmalogens and Fatty Acid Metabolites Associate with Retinal Microangiopathy in Participants from the Finnish Diabetes Prevention Study
de Mello, Vanessa Derenji; Selander, Tuomas; Lindström, Jaana; Tuomilehto, Jaakko; Uusitupa, Matti; Kaarniranta, Kai. 2021. Nutrients. 13: 4452 A1 Journal article (refereed), original research -
Successful years of collaboration between Acta Ophthalmologica and the European Association for Vision and Eye Research
Kaarniranta, Kai; Stefansson, Einar. 2021. Acta ophthalmologica. 99: 239 B1 Non-refereed journal articles -
TAS-116, a Well-Tolerated Hsp90 Inhibitor, Prevents the Activation of the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells
Ranta-aho, Sofia; Piippo, Niina; Korhonen, Eveliina; Kaarniranta, Kai; Hytti, Maria; Kauppinen, Anu. 2021. International journal of molecular sciences. 22: 4875 A1 Journal article (refereed), original research -
The most successful year in the history of Acta Ophthalmologica
Kaarniranta, Kai; Stefánsson, Einar. 2021. Acta ophthalmologica. 99: 117-117 B1 Non-refereed journal articles -
The state of your journal Acta Ophthalmologica 2020
Kaarniranta, Kai; Stefánsson, Einar. 2021. Acta ophthalmologica. 99: 467-469 B1 Non-refereed journal articles -
Therapeutic potential of PGC-1α in age-related macular degeneration (AMD) - the involvement of mitochondrial quality control, autophagy, and antioxidant response
Hyttinen, Juha; Blasiak, Janusz; Tavi, Pasi; Kaarniranta, Kai. 2021. Expert opinion on therapeutic targets. 25: 773-785 A2 Review article, Literature review, Systematic review -
Ultrasound and Microbubbles for the Treatment of Ocular Diseases: From Preclinical Research towards Clinical Application
Rousou, Charis; Schuurmans, Carl C. L.; Urtti, Arto; Mastrobattista, Enrico; Storm, Gert; Moonen, Chrit; Kaarniranta, Kai; Deckers, Roel. 2021. Pharmaceutics. 13: 1782 A2 Review article, Literature review, Systematic review -
Autophagy Genes for Wet Age-Related Macular Degeneration in a Finnish Case-Control Study
Paterno, Jussi J; Koskela, Ali; Hyttinen, Juha M T; Vattulainen, Elina; Synowiec, Ewelina; Tuuminen, Raimo; Watala, Cezary; Blasiak, Janusz; Kaarniranta, Kai. 2020. Genes. 11: 1318 A1 Journal article (refereed), original research -
Comparison of Two Different Treat-and-Extend Protocols with Afibercept in Wet Age-Related Macular Degeneration: Two-Year Results
Taipale, Claudia; Lindholm, Juha-Matti; Kaarniranta, Kai; Tuuminen, Raimo. 2020. Advances in therapy. 37: 2256-2266 A1 Journal article (refereed), original research -
Correlation Between the Rate of Intravitreal Injections, Use of Aflibercept as a Second-Line Treatment and Visual Impairment for Wet AMD in Finland
Karesvuo, Petteri; Hakkala, Laura; Kaarniranta, Kai; Uusitalo, Hannu; Ojamo, Matti; Tuuminen, Raimo. 2020. Acta ophthalmologica. 98: 472-476 A1 Journal article (refereed), original research -
DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - Alu RNA Accumulation versus miRNA Dysregulation
Kaarniranta, Kai; Pawlowska, Elzbieta; Szczepanska, Joanna; Blasiak, Janusz. 2020. Aging and disease. 11: 851-862 A2 Review article, Literature review, Systematic review -
Drug Flux Across RPE Cell Models: The Hunt for An Appropriate Outer Blood-Retinal Barrier Model for Use in Early Drug Discovery
Hellinen, Laura; Hongisto, Heidi; Ramsay, Eva; Kaarniranta, Kai; Vellonen, Kati-Sisko; Skottman, Heli; Ruponen, Marika. 2020. Pharmaceutics. 12: 176 A1 Journal article (refereed), original research -
ER stress activates immunosuppressive network: implications for aging and Alzheimer's disease
Salminen, Antero; Kaarniranta, Kai; Kauppinen, Anu. 2020. Journal of molecular medicine: jmm. 98: 633-650 A2 Review article, Literature review, Systematic review -
Exosomal vesicles enhance immunosuppression in chronic inflammation: Impact in cellular senescence and the aging process
Salminen, Antero; Kaarniranta, Kai; Kauppinen, Anu. 2020. Cellular signalling. 75: 109771 A2 Review article, Literature review, Systematic review -
Immunological biomarkers of the vitreous responsible for proliferative alteration in the different forms of retinal detachment
Balogh, Anikó; Milibák, Tibor; Szabó, Viktória; Nagy, Zoltán Zsolt; Kaarniranta, Kai; Resch, Miklós D. 2020. Bmc ophthalmology. 20: 491 A1 Journal article (refereed), original research -
In vitro stem cell modelling demonstrates a proof-of-concept for excess functional mutant TIMP3 as the cause of Sorsby Fundus Dystrophy
Hongisto, H; Dewing, JM; Christensen, DRG; Scott, J; Cree, AJ; Nättinen, J; Määttä, J; Jylhä, A; Aapola, U; Uusitalo, H; Kaarniranta, K; Ratnayaka, JA; Skottman, H; Lotery, AJ. 2020. Journal of pathology. 252: 138-150 A1 Journal article (refereed), original research -
Induction of Heat Shock Protein 70 in Mouse RPE as an In Vivo Model of Transpupillary Thermal Stimulation
Amirkavei, Mooud; Pitkänen, Marja; Kaikkonen, Ossi; Kaarniranta, Kai; André, Helder; Koskelainen, Ari. 2020. International journal of molecular sciences. 21: 2063 A1 Journal article (refereed), original research -
Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration
Kaarniranta, Kai; Uusitalo, Hannu; Blasiak, Janusz; Felszeghy, Szabolcs; Kannan, Ram; Kauppinen, Anu; Salminen, Antero; Sinha, Debasish; Ferrington, Deborah. 2020. Progress in retinal and eye research. 78: 100858 A1 Journal article (refereed), original research -
Mitophagy in the Retinal Pigment Epithelium of Dry Age-Related Macular Degeneration Investigated in the NFE2L2/PGC-1α-/- Mouse Model
Sridevi Gurubaran, Iswariyaraja; Viiri, Johanna; Koskela, Ali; Hyttinen, Juha M; Paterno, Jussi; Kis, Gréta; Antal, Miklós; Urtti, Arto; Kauppinen, Anu; Felszeghy, Szabolcs; Kaarniranta, Kai. 2020. International journal of molecular sciences. 21: 1976 A1 Journal article (refereed), original research -
Only IL-1ß release is inflammasome-dependent upon ultraviolet B irradiation although IL-18 is also secreted
Korhonen, Eveliina; Piippo, Niina; Hytti, Maria; Hyttinen, Juha; Kaarniranta, Kai; Kauppinen, Anu. 2020. Faseb journal. 34: 6437-6448 A1 Journal article (refereed), original research -
Potential Role of Myeloid-Derived Suppressor Cells (MDSCs) in Age-Related Macular Degeneration (AMD)
Kauppinen, Anu; Kaarniranta, Kai; Salminen, Antero. 2020. Frontiers in immunology. 11: 384 A2 Review article, Literature review, Systematic review -
Resvega Alleviates Hydroquinone-Induced Oxidative Stress in ARPE-19 Cells
Bhattarai, Niina; Korhonen, Eveliina; Toppila, Maija; Koskela, Ali; Kaarniranta, Kai; Mysore, Yashavanthi; Kauppinen, Anu. 2020. International journal of molecular sciences. 21: 2066 A1 Journal article (refereed), original research -
Resveratrol as Inducer of Autophagy, Pro-Survival, and Anti-Inflammatory Stimuli in Cultured Human RPE Cells
Josifovska, N; Albert, R; Nagymihály, R; Lytvynchuk, L; Moe, MC; Kaarniranta, K; Veréb, ZJ; Petrovski, G. 2020. International journal of molecular sciences. 21: 813 A1 Journal article (refereed), original research -
The Aging Stress Response and Its Implication for AMD Pathogenesis
Blasiak, Janusz; Pawlowska, Elzbieta; Sobczuk, Anna; Szczepanska, Joanna; Kaarniranta, Kai. 2020. International journal of molecular sciences. 21: 8840 A2 Review article, Literature review, Systematic review -
The role of vision-related problems in fatal road accidents in Finland
Wedenoja, Juho; Kalsi, Juhani; Salenius, Salla; Parkkari, Kalle; Kaarniranta, Kai; Tervo, Timo. 2020. Acta ophthalmologica. 2021; 99: 427-430 A1 Journal article (refereed), original research -
Trehalose for Ocular Surface Health
Laihia, Jarmo; Kaarniranta, Kai. 2020. Biomolecules. 10: 809 A2 Review article, Literature review, Systematic review -
UV-B-Induced Inflammasome Activation Can Be Prevented by Cis-Urocanic Acid in Human Corneal Epithelial Cells
Korhonen, Eveliina; Bisevac, Jovana; Hyttinen, Juha MT; Piippo, Niina; Hytti, Maria; Kaarniranta, Kai; Petrovski, Goran; Kauppinen, Anu. 2020. Investigative ophthalmology and visual science. 61: 7 A1 Journal article (refereed), original research -
Yhtenäiset vaatimukset lääketieteen ja hammaslääketieteen tohtorintutkinnolle Suomessa
Lehenkari, Petri; Tuovinen, Timo; Alahuhta, Seppo; Risteli, Leila; Ylöstalo, Pekka; Rämet, Mika; Parkkila, Seppo; Happo, Saara; Kaarniranta, Kai; Blom, Nina; Ritvos, Olli; Kähäri, Veli-Matti; Leivo, Ilmo; Heikinheimo, Markku. 2020. Duodecim. 136: 633-640 A1 Journal article (refereed), original research -
Zinc and Autophagy in Age-Related Macular Degeneration
Blasiak, Janusz; Pawlowska, Elzbieta; Chojnacki, Jan; Szczepanska, Joanna; Chojnacki, Cezary; Kaarniranta, Kai. 2020. International journal of molecular sciences. 21: 4994 A2 Review article, Literature review, Systematic review -
AMPK activation inhibits the functions of myeloid-derived suppressor cells (MDSC): impact on cancer and aging
Salminen, Antero; Kauppinen, Anu; Kaarniranta, Kai. 2019. Journal of molecular medicine: jmm. 97: 1049-1064 A2 Review article, Literature review, Systematic review -
Antimycin A-Induced Mitochondrial Damage Causes Human RPE Cell Death despite Activation of Autophagy
Hytti, Maria; Korhonen, Eveliina; Hyttinen, Juha M T; Roehrich, Heidi; Kaarniranta, Kai; Ferrington, Deborah A; Kauppinen, Anu. 2019. Oxidative medicine and cellular longevity. 2019: 1583656 A1 Journal article (refereed), original research -
Can vitamin D protect against age-related macular degeneration or slow its progression?
Kaarniranta, K; Pawlowska, E; Szczepanska, J; Jablkowska, A; Blasiak, J. 2019. Acta biochimica polonica. 66: 147-158 A2 Review article, Literature review, Systematic review -
Changes in ocular signs and symptoms in patients switching from bimatoprost-timolol to tafluprost-timolol eye drops: an open-label phase IV study
Bourne, RRA; Kaarniranta, K; Lorenz, K; Traverso, CE; Vuorinen, J; Ropo, A. 2019. BMJ open. 9: e024129 A1 Journal article (refereed), original research -
Compromised Barrier Function in Human Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells from Type 2 Diabetic Patients
Kiamehr, M; Klettner, A; Richert, E; Koskela, A; Koistinen, A; Skottman, H; Kaarniranta, K; Aalto-Setälä, K; Juuti-Uusitalo, K. 2019. International journal of molecular sciences. 20: 3773 A1 Journal article (refereed), original research -
Dietary Polyphenols in Age-Related Macular Degeneration: Protection against Oxidative Stress and Beyond
Pawlowska, E; Szczepanska, J; Koskela, A; Kaarniranta, K; Blasiak, J. 2019. Oxidative medicine and cellular longevity. 2019: 9682318 A2 Review article, Literature review, Systematic review -
Disease aetiology-based design of multifunctional microemulsion eye drops for moderate or severe dry eye: a randomized, quadruple-masked and active-controlled clinical trial
Laihia, J; Järvinen, R; Wylegala, E; Kaarniranta, K. 2019. Acta ophthalmologica. 2020; 98: 244-254 A1 Journal article (refereed), original research -
Electrical synapses interconnecting axons revealed in the optic nerve head - a novel model of gap junctions' involvement in optic nerve function
Smedowski, A; Akhtar, S; Liu, X; Pietrucha-Dutczak, M; Podracka, L; Toropainen, E; Alkanaan, A; Ruponen, M; Urtti, A; Varjosalo, M; Kaarniranta, K; Lewin-Kowalik, J. 2019. Acta ophthalmologica. [Epub ahead of print 10 Oct 2019]: 1-10 A1 Journal article (refereed), original research -
Expression of VEGFA-regulating miRNAs and mortality in wet AMD
Blasiak, J; Watala, C; Tuuminen, R; Kivinen, N; Koskela, A; Uusitalo-Järvinen, H; Tuulonen, A; Winiarczyk, M; Mackiewicz, J; Zmorzynski, S; Filip, A; Kaarniranta, K. 2019. Journal of cellular and molecular medicine. 23: 8464-8471 A1 Journal article (refereed), original research -
Fatty acids and oxidized lipoproteins contribute to autophagy and innate immunity responses upon the degeneration of retinal pigment epithelium and development of age-related macular degeneration
Kaarniranta, Kai; Koskela, Ali; Felszeghy, Szabolcs; Kivinen, Niko; Salminen, Antero; Kauppinen, Aanu. 2019. Biochimie. 159: 49-54 A2 Review article, Literature review, Systematic review -
Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium-Role in Dead Cell Clearance and Inflammation
Szatmári-Tóth, M; Ilmarinen, T; Mikhailova, A; Skottman, H; Kauppinen, A; Kaarniranta, K; Kristóf, E; Lytvynchuk, L; Veréb, Z; Fésüs, L; Petrovski, G. 2019. International journal of molecular sciences. 20: 926 A1 Journal article (refereed), original research -
Immunosenescence: the potential role of myeloid-derived suppressor cells (MDSC) in age-related immune deficiency
Salminen, Antero; Kaarniranta, Kai; Kauppinen, Anu. 2019. Cellular and molecular life sciences. 76: 1901-1918 A2 Review article, Literature review, Systematic review -
Interplay between Autophagy and the Ubiquitin-Proteasome System and Its Role in the Pathogenesis of Age-Related Macular Degeneration
Blasiak, J; Pawlowska, E; Szczepanska, J; Kaarniranta, K. 2019. International journal of molecular sciences. 20: 210 A2 Review article, Literature review, Systematic review -
Life Style Intervention Improves Retinopathy Status - The Finnish Diabetes Prevention Study
Aro, A; Kauppinen, A; Kivinen, N; Selander, T; Kinnunen, K; Tuomilehto, J; Keinänen-Kiukaanniemi, S; Lindström, J; Uusitupa, M; Kaarniranta, K. 2019. Nutrients. 11: 1691 A1 Journal article (refereed), original research -
Real Life Experience of Dexamethasone Implant in Refractory Diabetic Macular Oedema
Karttunen, Tommi; Nummelin, Lasse; Kaarniranta, Kai; Kinnunen, Kati. 2019. Clinical ophthalmology. 13: 2583-2590 A1 Journal article (refereed), original research -
Resvega alleviates oxidative stress and inflammasome activation in retinal pigment epithelial cells
Bhattarai, Niina; Korhonen, Eveliina; Toppila, Maija; Kaarniranta, Kai; Kauppinen, Anu. 2019. Acta ophthalmologica -
Role of Mitochondrial DNA Damage in ROS-Mediated Pathogenesis of Age-Related Macular Degeneration (AMD).
Kaarniranta, K; Pawlowska, E; Szczepanska, J; Jablkowska, A; Blasiak, J. 2019. International journal of molecular sciences. 20: 2374 A2 Review article, Literature review, Systematic review -
SQSTM1/p62 regulates the production of IL-8 and MCP-1 in IL-1ß-stimulated human retinal pigment epithelial cells
Korhonen, E; Piippo, N; Hytti, M; Hyttinen, JMT; Kaarniranta, K; Kauppinen, A. 2019. Cytokine. 116: 70-77 A1 Journal article (refereed), original research -
Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage
Zeiner, J; Loukovaara, S; Losenkova, K; Zuccarini, M; Korhonen, AM; Lehti, K; Kauppinen, A; Kaarniranta, K; Müller, CE; Jalkanen, S; Yegutkin, GG. 2019. Journal of molecular medicine: jmm. 97: 341-354 A1 Journal article (refereed), original research -
The Regulation of NFE2L2 (NRF2) Signalling and Epithelial-to-Mesenchymal Transition in Age-Related Macular Degeneration Pathology
Hyttinen, JMT; Kannan, R; Felszeghy, S; Niittykoski, M; Salminen, A; Kaarniranta, K. 2019. International journal of molecular sciences. 20: 5800 A2 Review article, Literature review, Systematic review -
The first ophthalmic Choosing Wisely recommendations in Finland for glaucoma and wet age-related macular degeneration
Tuuminen, R; Sipilä, R; Komulainen, J; Saarela, V; Kaarniranta, K; Tuulonen, A. 2019. Acta ophthalmologica. 97: e808-e810 B1 Non-refereed journal articles -
Ajokorttitodistusten näkövaatimukset
Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 376. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Asikloviiri
Seppänen, Matti; Setälä, Niko; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 433-434. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Atselastiini
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 469. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Atsitromysiini
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 434. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Autophagy Stimulus Promotes Early HuR Protein Activation and p62/SQSTM1 Protein Synthesis in ARPE-19 Cells by Triggering Erk1/2, p38MAPK, and JNK Kinase Pathways
Marchesi, Nicoletta; Thongon, Natthakan; Pascale, Alessia; Provenzani, Alessandro; Koskela, Ali; Korhonen, Eveliina; Smedowski, Adrian; Govoni, Stefano; Kauppinen, Anu; Kaarniranta, Kai; Amadio, Marialaura. 2018. Oxidative medicine and cellular longevity. 2018: 4956080 A1 Journal article (refereed), original research -
Bestin tauti
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 194-195. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Dinatriumkromoglikaatti
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 470-471. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Emedastiini
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 470. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Fluoreseiiniangiografia (FAG)
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 394-395. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Fluorokinolonit
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 434-435. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Fotodynaaminen hoito (PDT)
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 422. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Fusidiinihappo
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 435-436. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Gansikloviiri
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 436-437. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome
Piippo, N; Korhonen, E; Hytti, M; Skottman, H; Kinnunen, K; Josifovska, N; Petrovski, G; Kaarniranta, K; Kauppinen, A. 2018. Scientific reports. 8: 6720 A1 Journal article (refereed), original research -
Kefuroksiimi
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 437. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Klooritetrasykliini
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 437-438. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Kloramfenikoli
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 438-439. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Leikkauksenjälkeisen silmämunan sisäosien yleistulehduksen hoito
Kaarniranta, Kai; Marttila, Liisa; Seppänen, Matti. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 185-188. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Levokabastiini
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 471-472. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Lodoksamidi
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 472. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Loss of NRF-2 and PGC-1[alpha] genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration
Felszeghy, S; Viiri, J; Paterno, JJ; Hyttinen, JMT; Koskela, A; Chen, M; Leinonen, H; Tanila, H; Kivinen, N; Koistinen, A; Toropainen, E; Amadio, M; Smedowski, A; Reinisalo, M; Winiarczyk, M; Mackiewicz, J; Mutikainen, M; Ruotsalainen, AK; Kettunen, M; Jokivarsi, K; et al [Incl Kaarniranta, K; Kauppinen, A; Kinnunen, K; Levonen, A-L; Salminen, A; Tavi, P-P; Urtti, A]. 2018. Redox biology. 2019; 20: 1-12 A1 Journal article (refereed), original research -
Mechanistical retinal drug targets and challenges
Kaarniranta; Kai; Xu, Heping; Kauppinen, Anu. 2018. Advanced drug delivery reviews. 126: 177-184 A2 Review article, Literature review, Systematic review -
Mikrobinäytteen otto silmästä
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 407-409. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Mitochondrial quality control in AMD: does mitophagy play a pivotal role?
Hyttinen, Juha MT; Viiri, Johanna; Kaarniranta, Kai; Blasiak, Janusz. 2018. Cellular and molecular life sciences. 75: 2991-3008 A2 Review article, Literature review, Systematic review -
Molecular Mechanisms Underlying Age-Related Ocular Diseases
Amadio, Marialaura; Kaarniranta, Kai; Xu, Heping; Smedowski, Adrian; Ferrington, Deborah A. 2018. Oxidative medicine and cellular longevity. 2018: 1-2 B1 Non-refereed journal articles -
Myeloid-derived suppressor cells (MDSC): an important partner in cellular/tissue senescence
Salminen, Antero; Kauppinen, Anu; Kaarniranta, Kai. 2018. Biogerontology. 19: 325-329 A2 Review article, Literature review, Systematic review -
Natamysiini
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 439-440. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolemic mice
Ruotsalainen, Anna-Kaisa; Lappalainen, Jari P; Heiskanen, Emmi; Merentie, Mari; Näpänkangas, Juha; Lottonen-Raikaslehto, Line; Kansanen, Emilia; Adinolfi, Simone; Kaarniranta, Kai; Ylä-Herttuala, Seppo; Jauhiainen, Matti; Pirinen, Eija; Levonen, Anna-Liisa. 2018. Cardiovascular research. 2019; 115: 243-254 A1 Journal article (refereed), original research -
Olopatadiini
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 472-473. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Optinen valokerroskuvaus (OCT)
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 396-397. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Oxidative Stress is the Principal Contributor to Inflammasome Activation in Retinal Pigment Epithelium Cells with Defunct Proteasomes and Autophagy
Piippo, Niina; Korhonen, Eveliina; Hytti, Maria; Kinnunen, Kati; Kaarniranta, Kai; Kauppinen, Anu. 2018. Cellular physiology and biochemistry. 49: 359-367 A1 Journal article (refereed), original research -
PGC-1alfa Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis
Kaarniranta, Kai; Kajdanek, Jakub; Morawiec, Jan; Pawlowska, Elzbieta; Blasiak, Janusz. 2018. International journal of molecular sciences. 19: 2317 A2 Review article, Literature review, Systematic review -
Phytochemicals inhibit the immunosuppressive functions of myeloid-derived suppressor cells (MDSC): Impact on cancer and age-related chronic inflammatory disorders.
Salminen, Antero; Kaarniranta, Kai; Kauppinen, Anu. 2018. International immunopharmacology. 61: 231-240 A2 Review article, Literature review, Systematic review -
Propamidiini
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 440. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Seroosi retinopatia, nesteinen keskeisen verkkokalvon sairaus
Kivinen, Niko; Kaarniranta, Kai. 2018. Lääkärilehti. 73: 1940-1943 A2 Review article, Literature review, Systematic review -
Siklosporiini
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 480-481. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Silmänpohjan ikärappeumat
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 192-194. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Silmänpohjan kuvantaminen yleistyy ja tarkentuu
Kivinen, Niko; Tuulonen, Anja; Kaarniranta, Kai. 2018. Duodecim. 134: 1235-1243 A2 Review article, Literature review, Systematic review -
Silmätautien käsikirja
Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu. 2018. . . Duodecim D6 Edited professional book -
Silmävärve (nystagmus)
Seppänen, Matti; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 290-291. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Special issue on Molecular Mechanisms Underlying Age-Related Ocular Diseases
Amadio, Marialaura; Kaarniranta, Kai; Xu, Heping; Smedowski, Adrian; Ferrington, Deborah A. 2018. Oxidative medicine and cellular longevity. . Hindawi publishing corporation C2 Edited book, conference proceedings or special issue of a journal -
Suppressed heat shock protein response in the kidney of exercise-trained diabetic rats
Lappalainen, J; Oksala, NKJ; Laaksonen, DE; Khanna, S; Kokkola, T; Kaarniranta, K; Sen, CK; Atalay, M. 2018. Scandinavian journal of medicine and science in sports. 28: 1808-1817 A1 Journal article (refereed), original research -
Survival and functionality of xeno-free human embryonic stem cell-derived retinal pigment epithelial cells on polyester substrate after transplantation in rabbits
Ilmarinen, T; Thieltges, F; Hongisto, H; Juuti-Uusitalo, K; Koistinen, A; Kaarniranta, K; Brinken, R; Braun, N; Holz, FG; Skottman, H; Stanzel, BV. 2018. Acta ophthalmologica. 2019; 97: e688-e699 A1 Journal article (refereed), original research -
Tear film proteome in age-related macular degeneration
Winiarczyk, Mateusz; Kaarniranta, Kai; Winiarczyk, Stanislaw; Adaszek, Lukasz; Winiarczyk, Dagmara; Mackiewicz, Jerzy. 2018. Graefes archive for clinical and experimental ophthalmology. 256: 1127-1139 A1 Journal article (refereed), original research -
The potential importance of myeloid-derived suppressor cells (MDSCs) in the pathogenesis of Alzheimer's disease
Salminen, Antero; Kaarniranta, Kai; Kauppinen, Anu. 2018. Cellular and molecular life sciences. 75: 3099-3120 A2 Review article, Literature review, Systematic review -
The role of myeloid-derived suppressor cells (MDSC) in the inflammaging process
Salminen, Antero; Kaarniranta, Kai; Kauppinen, Anu. 2018. Ageing research reviews. 48: 1-10 A2 Review article, Literature review, Systematic review -
Tobramysiini
Seppänen, Matti; Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 440-441. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Verkkokalvohalkio
Kaarniranta, Kai. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 182-183. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Verkkokalvon keskeinen nesteirtauma
Kivinen, Niko; Kaarniranta, Kai; Seppänen, Matti. Teoksessa: Seppänen, Matti; Holopainen, Juha; Kaarniranta, Kai; Setälä, Niko; Uusitalo, Hannu(toim.) , 2018. Silmätautien käsikirja. s. 184-185. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Wound healing of human embryonic stem cell-derived retinal pigment epithelial cells is affected by maturation stage
Khamidakh, Amna E Abu; Rodriguez-Martinez, Alejandra; Kaarniranta, Kai; Kallioniemi, Anne; Skottman, Heli; Hyttinen, Jari; Juuti-Uusitalo, Kati. 2018. Biomedical engineering online. 17: 102 A1 Journal article (refereed), original research -
Autophagy Regulates Proteasome Inhibitor-Induced Pigmentation in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells
Juuti-Uusitalo K, Koskela A, Kivinen N, Viiri J, Hyttinen JMT, Reinisalo M, Koistinen A, Uusitalo H, Sinha D, Skottman H, Kaarniranta K. 2017. International journal of molecular sciences. 18: 1089 A1 Journal article (refereed), original research -
CB2 receptor activation causes an ERK1/2-dependent inflammatory response in human RPE cells
Hytti M, Andjelic S, Josifovska N, Piippo N, Korhonen E, Hawlina M, Kaarniranta K, Nevalainen TJ, Petrovski G, Parkkari T, Kauppinen A. 2017. Scientific reports. 7: 16169 A1 Journal article (refereed), original research -
Cellular Senescence in Age-Related Macular Degeneration: Can Autophagy and DNA Damage Response Play a Role?
Blasiak Janusz, Piechota Malgorzata, Pawlowska Elzbieta, Szatkowska Magdalena, Sikora Ewa, Kaarniranta Kai. 2017. Oxidative medicine and cellular longevity. 2017: 5293258 A2 Review article, Literature review, Systematic review -
Contacting co-culture of human retinal microvascular endothelial cells alters barrier function of human embryonic stem cell derived retinal pigment epithelial cells
Skottman H, Muranen J, Lähdekorpi H, Pajula E, Mäkelä K, Koivusalo L, Koistinen A, Uusitalo H, Kaarniranta K, Juuti-Uusitalo K. 2017. Experimental cell research. 359: 101-111 A1 Journal article (refereed), original research -
Cytoarchitecture of epithelial inflammatory infiltration indicates the aetiology of infectious keratitis
Smedowski A, Tarnawska D, Orski M, Wroblewska-Czajka E, Kaarniranta K, Aragona P, Wylegala E. 2017. Acta ophthalmologica. 95: 405-413 A1 Journal article (refereed), original research -
DNA damage response and autophagy in the degeneration of retinal pigment epithelial cells - Implications for age-related macular degeneration (AMD)
Hyttinen JMT, Blasiak J, Niittykoski M, Kinnunen K, Kauppinen A, Salminen A, Kaarniranta K. 2017. Ageing research reviews. 36: 64-77 A2 Review article, Literature review, Systematic review -
Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model
Roginska Dorota, Kawa Milosz P, Pius-Sadowska Ewa, Lejkowska Renata, Luczkowska Karolina, Wiszniewska Barbara, Kaarniranta Kai, Paterno Jussi J, Schmidt Christian A, Machalinski Boguslaw, Machalinska Anna. 2017. Oxidative medicine and cellular longevity. 2017: 5306790 A1 Journal article (refereed), original research -
Hypoxia and inflammation in the release of VEGF and interleukins from human retinal pigment epithelial cells
Arjamaa Olli, Aaltonen Vesa, Piippo Niina, Csont Tamás, Petrovski Goran, Kaarniranta Kai, Kauppinen Anu. 2017. Graefes archive for clinical and experimental ophthalmology. 255: 1757-1762 A1 Journal article (refereed), original research -
Hypoxia/ischemia activate processing of Amyloid Precursor Protein: impact of vascular dysfunction in the pathogenesis of Alzheimer's disease
Salminen Antero, Kauppinen Anu, Kaarniranta Kai. 2017. Journal of neurochemistry. 140: 536-549 A2 Review article, Literature review, Systematic review -
Increased intraocular pressure alters the cellular distribution of HuR protein in retinal ganglion cells : a possible sign of endogenous neuroprotection failure
Smedowski A, Liu X, Podracka L, Akhtar S, Trzeciecka A, Pietrucha-Dutczak M, Lewin-Kowalik J, Urtti A, Ruponen M, Kaarniranta K, Varjosalo M, Amadio M. 2017. Biochimica et biophysica acta: molecular basis of disease. 2018; 1864: 296-306 A1 Journal article (refereed), original research -
Individual benefits of enoxaparin treatment in branch vein occlusion
Dragoni, Francesco; Kaarniranta, Kai. 2017. Graefes archive for clinical and experimental ophthalmology. 2018; 256: 1031-1033 B1 Non-refereed journal articles -
Integrated stress response stimulates FGF21 expression: Systemic enhancer of longevity
Salminen A, Kaarniranta K, Kauppinen A. 2017. Cellular signalling. 40: 10-21 A2 Review article, Literature review, Systematic review -
Lysosomal destabilization activates the NLRP3 inflammasome in human umbilical vein endothelial cells (HUVECs)
Kinnunen K, Piippo N, Loukovaara S, Hytti M, Kaarniranta K, Kauppinen A. 2017. Journal of cell communication and signaling. 11: 275-279 A1 Journal article (refereed), original research -
NLRP3 inflammasome activation is associated with proliferative diabetic retinopathy
Loukovaara S, Piippo N, Kinnunen K, Hytti M, Kaarniranta K, Kauppinen A. 2017. Acta ophthalmologica. 95: 803-808 A1 Journal article (refereed), original research -
Outcome of anti-vascular endothelial growth factor therapy for neovascular age-related macular degeneration in real-life setting
Kataja, M; Hujanen, P; Huhtala, H; Kaarniranta, K; Tuulonen, A; Uusitalo-Jarvinen, H. 2017. British journal of ophthalmology. 2018; 102: 959-965 A1 Journal article (refereed), original research -
Oxidative Stress, Epigenetics, Environment, and Epidemiology of Diabetic Retinopathy
Petrovski G, Kaarniranta K, Petrovic D. 2017. Journal of Diabetes Research. [Published online 2017 Feb 22]: 1-2 A1 Journal article (refereed), original research -
Oxidized low-density lipoprotein, lipid and calcium aggregates reveal oxidative stress and inflammation in the conjunctiva of glaucoma patients
Helin-Toiviainen M, Rönkkö S, Kaarniranta K, Puustjärvi T, Rekonen P, Ollikainen M, Uusitalo H. 2017. Acta ophthalmologica. 95: 378-385 A1 Journal article (refereed), original research -
Predictive factors in endonasal endoscopic lacrimal surgery: a review
Penttilä E, Smirnov G, Kaarniranta K, Seppä J, Tuomilehto H. 2017. B-ent. 13: 129-135 A2 Review article, Literature review, Systematic review -
Regulation of longevity by FGF21: Interaction between energy metabolism and stress responses
Salminen Antero, Kaarniranta Kai, Kauppinen Anu. 2017. Ageing research reviews. 37: 79-93 A2 Review article, Literature review, Systematic review -
Silmänpohjan ikärappeuman patogeneesi - autofagian ja inflammasomien vuoropuhelua
Kivinen Niko, Koskela Ali, Kauppinen Anu, Kaarniranta kai. 2017. Duodecim. 133: 641-646 A2 Review article, Literature review, Systematic review -
The Finnish national guideline for diagnosis, treatment and follow-up of patients with wet age related macular degeneration
Tuuminen Raimo, Uusitalo-Järvinen Hannele, Aaltonen Vesa, Hautala Nina, Kaipiainen Sulevi, Laitamäki Nina, Ollila Marko, Rantanen Jari, Välimäki Satu, Sipilä Raija, Laukkala Tanja, Komulainen Jorma, Tommila Petri, Immonen Ilkka, Tuulonen Anja, Kaarniranta Kai. 2017. Acta ophthalmologica. 95: 1-9 A2 Review article, Literature review, Systematic review -
The Finnish national guideline for diagnosis, treatment and follow-up of patients with wet age-related macular degeneration
Tuuminen R, Tuulonen A, Kaarniranta K. 2017. Acta ophthalmologica. 95: 649-650 B1 Non-refereed journal articles -
The Nobel Prized cellular target autophagy in eye diseases
Kaarniranta Kai, Petrovski Goran, Kauppinen Anu. 2017. Acta ophthalmologica. 95: 335-336 B1 Non-refereed journal articles -
Topical cis-urocanic acid prevents ocular surface irritation in both IgE -independent and -mediated rat model
Jauhonen HM, Laihia J, Oksala O, Viiri J, Sironen R, Alajuuma P, Kaarniranta K, Leino L. 2017. Graefes archive for clinical and experimental ophthalmology. 255: 2357-2362 A1 Journal article (refereed), original research -
Two dietary polyphenols, fisetin and luteolin, reduce inflammation but augment DNA damage-induced toxicity in human RPE cell
Hytti M, Szabó D, Piippo N, Korhonen E, Honkakoski P, Kaarniranta K, Petrovski G, Kauppinen A. 2017. Journal of nutritional biochemistry. 42: 37-42 A1 Journal article (refereed), original research -
Visual processing in patients with age-related macular degeneration performing a face detection test
Vottonen Pasi, Kaarniranta Kai, Pääkkönen Ari, Tarkka Ina M. 2017. Clinical ophthalmology. 11: 1245-1252 A1 Journal article (refereed), original research -
AMPK and HIF signaling pathways regulate both longevity and cancer growth: the good news and the bad news about survival mechanisms
Salminen Antero, Kaarniranta Kai, Kauppinen Anu. 2016. Biogerontology. 17: 655-680 A2 Review article, Literature review, Systematic review -
AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions
Salminen Antero, Kauppinen Anu, Kaarniranta Kai. 2016. Cellular signalling. 28: 887-895 A2 Review article, Literature review, Systematic review -
Absence of collagen XVIII in mice causes age-related insufficiency in retinal pigment epithelium proteostasis
Kivinen Niko, Felszeghy Szabolcs, Kinnunen Aino I, Setälä Niko, Aikio Mari, Kinnunen Kati, Sironen Reijo, Pihlajaniemi Taina, Kauppinen Anu, Kaarniranta Kai. 2016. Biogerontology. 17: 749-761 A1 Journal article (refereed), original research -
Age-related changes in AMPK activation: Role for AMPK phosphatases and inhibitory phosphorylation by upstream signaling pathways
Salminen Antero, Kaarniranta Kai, Kauppinen Anu. 2016. Ageing research reviews. 28: 15-26 A2 Review article, Literature review, Systematic review -
All-Trans Retinoic Acid Modulates DNA Damage Response and the Expression of the VEGF-A and MKI67 Genes in ARPE-19 Cells Subjected to Oxidative Stress
Tokarz Paulina, Piastowska-Ciesielska Agnieszka Wanda, Kaarniranta Kai, Blasiak Janusz. 2016. International journal of molecular sciences. 17: 898 A1 Journal article (refereed), original research -
Autophagy regulates death of retinal pigment epithelium cells in age-related macular degeneration
Kaarniranta K, Tokarz P, Koskela A, Paterno J, Blasiak J. 2016. Cell biology and toxicology. 2017; 33: 113-128 A2 Review article, Literature review, Systematic review -
Benefits of switching from latanoprost to preservative-free tafluprost eye drops: a meta-analysis of two Phase IIIb clinical trials
Uusitalo Hannu, Egorov Evjeniy, Kaarniranta Kai, Astakhov Yuri, Ropo Auli. 2016. Clinical ophthalmology. 10: 445-454 A1 Journal article (refereed), original research -
Clearance of autophagy-associated dying retinal pigment epithelial cells - a possible source for inflammation in age-related macular degeneration
Szatmári-Tóth M, Kristóf E, Veréb Z, Akhtar S, Facskó A, Fésus L, Kauppinen A, Kaarniranta K, Petrovski G. 2016. Cell death and disease. 7: e2367 A1 Journal article (refereed), original research -
Dry Eye Disease - Nordic Guidelines 2016
Heegaard S, Knudsen LL, van Setten G, Koranyi G, Holopainen J, Kaarniranta K, Klyve P, Raeder S. 2016. . . - D6 Edited professional book -
FGF21 activates AMPK signaling: impact on metabolic regulation and the aging process
Salminen Antero, Kauppinen Anu, Kaarniranta Kai. 2016. Journal of molecular medicine: jmm. 2017; 95: 123-131 A2 Review article, Literature review, Systematic review -
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Klionsky Daniel J, Abdelmohsen Kotb, Abe Akihisa, Abedin Md Joynal, Abeliovich Hagai, Acevedo Arozena Abraham, Adachi Hiroaki, Adams Christopher M, Adams Peter D, Adeli Khosrow, Adhihetty Peter J, Adler Sharon G, Agam Galila, Agarwal Rajesh, Aghi Manish K, Agnello Maria, Agostinis Patrizia, Aguilar Patricia V, Aguirre-Ghiso Julio, Airoldi Eduardo M et al. 2016. Autophagy. 12: 1-222 A1 Journal article (refereed), original research -
Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases
Salminen Antero, Kaarniranta Kai, Kauppinen Anu. 2016. Aging and disease. 7: 180-200 A2 Review article, Literature review, Systematic review -
Inflammation and its role in age-related macular degeneration
Kauppinen Anu, Paterno Jussi J, Blasiak Janusz, Salminen Antero, Kaarniranta Kai. 2016. Cellular and molecular life sciences. 73: 1765-1786 A2 Review article, Literature review, Systematic review -
Inhibition of BET bromodomains alleviates inflammation in human RPE cells
Hytti Maria, Tokarz P, Määttä E, Piippo Niina, Korhonen Eveliina, Suuronen T, Honkakoski Paavo, Kaarniranta Kai, Lahtela-Kakkonen Maija, Kauppinen Anu. 2016. Biochemical pharmacology. 110-111: 71-79 A1 Journal article (refereed), original research -
Inhibition of DNA methyltransferase or histone deacetylase protects retinal pigment epithelial cells from DNA damage induced by oxidative stress by the stimulation of antioxidant enzymes
Tokarz Paulina, Kaarniranta Kai, Blasiaka Janusz. 2016. European journal of pharmacology. 776: 167-175 A1 Journal article (refereed), original research -
Kostea silmänpohjan ikärappeuma (AMD)
Tuuminen R, Uusitalo-Järvinen H, Aaltonen V, Hautala N, Kaipiainen S, Laitamäki N, Ollila M, Rantanen J, Välimäki S, Sipilä R, Laukkala T, Komulainen J, Tommila P, Immonen I, Tuulonen A, Kaarniranta K. Teoksessa: -(toim.) , 2016. Käypä hoito. Suomalaisen Lääkäriseuran Duodecimin ja Suomen Fysiatriyhdistyksen asettama työryhmä. s. -. Duodecim D2 Article in a professional book (incl. an introduction by the editor) -
Long-term topical application of preservative-free prostaglandin analogues evokes macrophage infiltration in the ocular adnexa
Trzeciecka Anna, Paterno J Jussi, Toropainen Elisa, Koskela Ali, Podracka Lucia, Korhonen Eveliina, Kauppinen Anu, Kaarniranta Kai, Smedowski Adrian. 2016. European journal of pharmacology. 788: 12-20 A1 Journal article (refereed), original research -
Lääketieteen Nobelin palkinto autofagian tutkijalle
Kaarniranta Kai, Meri Seppo, Eskelinen Eeva-Liisa. 2016. Duodecim. 132: 2141-2144 D1 Article in a trade journal -
Melatonin in retinal physiology and pathology: the case of age-related macular degeneration
Blasiak J, Reiter RJ, Kaarniranta K. 2016. Oxidative medicine and cellular longevity. 2016: 6819736, 12 pages A2 Review article, Literature review, Systematic review -
Nutraceutical with Resveratrol and Omega-3 Fatty Acids Induces Autophagy in ARPE-19 Cells
Koskela Ali, Reinisalo Mika, Petrovski Goran, Sinha Debasish, Olmiere Céline, Karjalainen Reijo, Kaarniranta Kai. 2016. Nutrients. 8: 284 A1 Journal article (refereed), original research -
Nya behandlingar vid synhotande makulasjukdomer
Paterno J, Ikäheimo K, Kinnunen K, Kaarniranta K. 2016. Finska läkaresällskapets handlingar. 176: 10-14 A1 Journal article (refereed), original research -
2-Oxoglutarate-dependent dioxygenases are sensors of energy metabolism, oxygen availability, and iron homeostasis: potential role in the regulation of aging process
Salminen Antero, Kauppinen Anu, Kaarniranta Kai. 2015. Cellular and molecular life sciences. 72: 3897-3914 A1 Journal article (refereed), original research -
A novel proteotoxic stress associated mechanism for macular corneal dystrophy
Kaarniranta Kai, Szalai Eszter, Smedowski Adrian, Hegyi Zoltán, Kivinen Niko, Viiri Johanna, Wowra Bogumil, Dobrowolski Dariusz, Módis Jr. László, Berta András, Wylegala Edward, Felszeghy Szabolcs. 2015. Histology and histopathology. 30: 921-930 A1 Journal article (refereed), original research -
A randomized phase I clinical study of cis-urocanic acid eye drops in healthy adult subjects
Jauhonen Hanna-Mari, Kari Eeva, Pylkkänen Liisa, Poutanen Jutta, Laihia Jarmo, Kaarniranta Kai, Leino Lasse. 2015. Acta ophthalmologica. 93: 368-376 A1 Journal article (refereed), original research -
Ageing of the vitreous: From acute onset floaters and flashes to retinal detachment
Lumi Xhevat, Hawlina Marko, Glavac Damjan, Facsko Andrea, Moe Morten C, Kaarniranta Kai, Petrovski Goran. 2015. Ageing research reviews. 21: 71-77 A2 Review article, Literature review, Systematic review -
Autophagy in DNA Damage Response
Czarny Piotr, Pawlowska Elzbieta, Bialkowska-Warzecha Jolanta, Kaarniranta Kai, Blasiak Janusz. 2015. International journal of molecular sciences. 16: 2641-2662 A2 Review article, Literature review, Systematic review -
Best-corrected visual acuity and retinal thickness are associated with improved cortical visual processing in treated wet AMD patients
Vottonen Pasi, Pääkkönen Ari, Tarkka Ina M, Kaarniranta Kai. 2015. Acta ophthalmologica. 93: 621-25 A1 Journal article (refereed), original research -
Climatic droplet keratopathy: an old disease in new clothes
Serra Horacio M, Holopainen Juha M, Beuerman Roger, Kaarniranta Kai, Suarez Maria F, Urrets-Zavalia Julio A. 2015. Acta ophthalmologica. 93: 496-504 A2 Review article, Literature review, Systematic review -
Defects in retinal pigment epithelial cell proteolysis and the pathology associated with age-related macular degeneration
Ferrington Deborah A, Sinha Debasish, Kaarniranta Kai. 2015. Progress in retinal and eye research. 2016; 51: 69-89 A2 Review article, Literature review, Systematic review -
Diabeettisen retinopatian uudet hoidot ja diagnostiikka
Karttunen Tommi, Kaarniranta Kai, Kinnunen Kati. 2015. DIABETES JA LÄÄKÄRI. 44: 17-22 D1 Article in a trade journal -
Endoscopic dacryocystorhinostomy as treatment for lower lacrimal pathway obstructions in adults : Review article
Penttilä Elina, Smirnov Grigori, Tuomilehto Henri, Kaarniranta Kai, Seppä Juha. 2015. Allergy and rhinology. 6: e12-e19 A2 Review article, Literature review, Systematic review -
Fisetin and luteolin protect human retinal pigment epithelial cells from oxidative stress-induced cell death and regulate inflammation
Hytti Maria, Piippo Niina, Korhonen Eveliina, Honkakoski Paavo, Kaarniranta Kai, Kauppinen Anu. 2015. Scientific reports. 5: A1 Journal article (refereed), original research -
Health-related quality of life after caract surgery with the phacoemulsification technique and intraocular lens implantation
Porela-Tiihonen Susanna, Roine Risto P, Sintonen Harri, Kaarniranta Kai, Kokki Merja, Kokki Hannu. 2015. Acta ophthalmologica. 2016; 94: 21-25 A1 Journal article (refereed), original research -
Impaired mitochondrial energy metabolism in Alzheimer's disease: Impact on pathogenesis via disturbed epigenetic regulation of chromatin landscape
Salminen Antero, Haapasalo Annakaisa, Kauppinen Anu, Kaarniranta Kai, Soininen Hilkka, Hiltunen Mikko. 2015. Progress in neurobiology. epub ahead of print 19 May 2015: A1 Journal article (refereed), original research -
Lysosomes: Regulators of autophagy in the retinal pigmented epithelium
Sinha Debasish, Valapala Mallika, Shang Peng, Hose Stacey, Grebe Rhonda, Lutty Gerard A, Zigler Jr J Samuel, Kaarniranta Kai, Handa James T. 2015. Experimental eye research. 144 (2016): 46-53 A2 Review article, Literature review, Systematic review -
Pharmacokinetics, Efficacy, and Safety of the Preservative-free Fixed Combination of Tafluprost 0.0015 % and Timolol 0.5 % in Healthy Volunteers: A Phase I Comparison vs. the Corresponding Preservative-free Monotherapies
Kaarniranta Kai, Ikäheimo Kirsi, Mannermaa Eliisa, Ropo Auli. 2015. Clinical pharmacokinetics. [epub ahead of print 21 Sep 2015]: 1-10 A1 Journal article (refereed), original research -
Polyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related Diseases
Reinisalo Mika, Kårlund Anna, Koskela Ali, Kaaniranta Kai, Karjalainen Reijo O.. 2015. Oxidative medicine and cellular longevity. 2015, Article ID 340520: 24 p. A2 Review article, Literature review, Systematic review -
Quercetin alleviates 4-hydroxynonenal-induced cytotoxicity and inflammation in ARPE-19 cells
Hytti Maria, Piippo Niina, Salminen Antero, Honkakoski Paavo, Kaarniranta Kai, Kauppinen Anu. 2015. Experimental eye research. 132: 208-215 A1 Journal article (refereed), original research -
Role of the cell cycle re-initiation in DNA damage response of post-mitotic cells and its implication in the pathogenesis of neurodegenerative diseases
Tokarz Paulina, Kaarniranta Kai, Blasiak Janusz. 2015. Rejuvenation research. 19: 1-9 A1 Journal article (refereed), original research -
The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells
Johansson Ida, Monsen Vivi Talstad, Pettersen Kristine, Mildenberger Jennifer, Misund Kristine, Kaarniranta Kai, Schønberg Svanhild, Bjørkøy Geir. 2015. Autophagy. 11: 1636-1651 A1 Journal article (refereed), original research -
A 6-month study comparing efficacy, safety, and tolerability of the preservative-free fixed combination of tafluprost 0.0015% and timolol 0.5% versus each of its individual preservative-free components
Pfeiffer N, Traverso CE, Lorenz K, Saarela V, Liinamaa J, Uusitalo H, Astakhov Y, Boiko E, Ropo A, Preservative-free Tafluprost/Timolol Fixed Combination Study Group Collaborators: Uusitalo H, Kaarniranta K,Saarela V, Pfeiffer N, Bartz-Schmidt U, Dunker S, Hamacher T, Heidemann K,Hofmann G, et al.. 2014. Advances in therapy. 31: 1228-1246 A1 Journal article (refereed), original research -
A rat experimental model of glaucoma incorporating rapid-onset elevation of intraocular pressure
Smedowski A, Pietrucha-Dutczak M, Kaarniranta K, Lewin-Kowalik J. 2014. Scientific reports. 4: 5910; 1-11 A1 Journal article (refereed), original research -
ADAMTS9 locus associates with increased risk of wet AMD
Helisalmi Seppo, Immonen Ilkka, Losonczy Gergely, Resch Miklos D, Benedek Szabolcs, Balogh Istvan, Papp Andras, Berta Andras, Uusitupa Matti, Hiltunen Mikko, Kaarniranta Kai. 2014. Acta ophthalmologica. 2014: 1 A1 Journal article (refereed), original research -
Bevacizumab does not affect autophagy clearance during proteasomal inhibition in human retinal pigment epithelial cells
Kivinen Niko, Dithmer Michaela, Kinnunen Kati, Lucius Ralph, Roider Johann, Kaarniranta Kai, Klettner Alexa. 2014. Journal of biochemical and pharmacological research. 2: 44-53 A1 Journal article (refereed), original research -
CB2 receptor as a potential target in age-related diseases
Kauppinen Anu, Nevalainen Tapio, Hytti Maria, Salminen Antero, Kaarniranta Kai, Parkkari Teija. 2014. Journal of biochemical and pharmacological research. 2: 33-43 A2 Review article, Literature review, Systematic review -
Cationorm shows good tolerability on human HCE-2 corneal epithelial cell cultures
Kinnunen Kati, Kauppinen Anu, Piippo Niina, Koistinen Arto, Toropainen Elisa, Kaarniranta Kai. 2014. Experimental eye research. 120: 82-89 A1 Journal article (refereed), original research -
Clearance of misfolded and aggregated proteins by aggrephagy and implications for aggregation diseases
Hyttinen JM, Amadio M, Viiri J, Pascale A, Salminen A, Kaarniranta K. 2014. Ageing research reviews. 18: 16-28 A2 Review article, Literature review, Systematic review -
Comparison of three intraocular pressure measurement methods including biomechanical properties of the cornea
Smedowski Adrian, Weglarz Beata, Tarnawska Dorota, Kaarniranta Kai, Wylegala Edward. 2014. Investigative ophthalmology and visual science. 55: 666-673 A1 Journal article (refereed), original research -
Decline in cellular clearance systems induces inflammasome signaling in human ARPE-19 cells
Piippo N, Korkmaz A, Hytti M, Kinnunen K, Salminen A, Atalay M, Kaarniranta K, Kauppinen A. 2014. Biochimica et biophysica acta: molecular cell research. 1843: 3038-3046 A1 Journal article (refereed), original research -
Estrogen Signalling in the Pathogenesis of Age-Related Macular Degeneration
Kaarniranta Kai, Machalinska Anna, Veréb Zoltán, Salminen Antero, Petrovski Goran, Kauppinen Anu. 2014. Current eye research. 2014: 1-8 A2 Review article, Literature review, Systematic review -
Excipients of preservative-free latanoprost induced inflammatory response and cytotoxicity in immortalized human HCE-2 corneal epithelial cells
Smedowski Adrian, Paterno Jussi J, Toropainen Elisa,Sinha Debasish, Wylegala Edward, Kaarniranta Kai. 2014. Journal of biochemical and pharmacological research. 2: 175-184 A1 Journal article (refereed), original research -
Herpes simplex virus types 1 and 2 modulate autophagy in SIRC corneal cells
Petrovski G, Pásztor K, Orosz L, Albert R, Mencel E, Moe MC, Kaarniranta K, Facskó A, Megyeri K. 2014. Journal of biosciences. 39: 683-692 A1 Journal article (refereed), original research -
Histone demethylase Jumonji D3 (JMJD3/KDM6B) at the nexus of epigenetic regulation of inflammation and the aging process
Salminen Antero, Kaarniranta Kai, Hiltunen Mikko, Kauppinen Anu. 2014. Journal of molecular medicine: jmm. -: - A2 Review article, Literature review, Systematic review -
Hsp70 binds reversibly to proteasome inhibitor-induced protein aggregates and evades autophagic clearance in ARPE-19 cells
Kivinen Niko, Hyttinen Juha MT, Viiri Johanna, Paterno Jussi, Felszheghy Szabolcs, Kauppinen Anu, Salminen Antero, Kaarniranta Kai. 2014. Journal of biochemical and pharmacological research. 2: 1-7 A1 Journal article (refereed), original research -
Hypoxic conditions stimulate the release of B-type natriuretic peptide from human retinal pigment epithelium cell culture
Aaltonen Vesa, Kinnunen Kati, Jouhilahti Eeva-Mari, Peltonen Juha, Nikinmaa Mikko, Kaarniranta Kai, Arjamaa Olli. 2014. Acta ophthalmologica. 92: 740-744 A1 Journal article (refereed), original research -
Inflammaging Signaling in Health Span and Life Span Regulation: Next Generation Targets for Longevity
Salminen A, Kauppinen A, Kaarniranta K. Teoksessa: Irfan Rahman and Debasis Bagchi(toim.) , 2014. Inflammation, Advancing Age and Nutrition: Research and Clinical Interventions. s. 323-332. Academic press A3 Book section, Chapters in research books -
Krebs cycle dysfunction shapes epigenetic landscape of chromatin: Novel insights into mitochondrial regulation of aging process
Salminen Antero, Kaarniranta Kai, Hiltunen Mikko, Kauppinen Anu. 2014. Cellular signalling. 26: 1598-1603 A2 Review article, Literature review, Systematic review -
Krebs cycle intermediates regulate DNA and histone methylation: Epigenetic impact on the aging process
Salminen Antero, Kauppinen Anu, Hiltunen Mikko, Kaarniranta Kai. 2014. Ageing research reviews. 16: 45-65 A2 Review article, Literature review, Systematic review -
Natural thermal adaptation increases heat shock protein levels and decreases oxidative stress
Oksala Niku KJ, Ekmekci F Güler, Özsoy Ergi, Kirankaya Serife, Kokkola Tarja, Emecen Güzin, Lappalainen Jani, Kaarniranta Kai, Atalay Mustafa. 2014. Redox biology. 3: 25-28 A1 Journal article (refereed), original research -
Oxidative Stress Protection by Exogenous Delivery of rhHsp70 Chaperone to the Retinal Pigment Epithelium (RPE), a Possible Therapeutic Strategy Against RPE Degeneration
Subrizi Astrid, Toropainen Elisa, Ramsay Eva, Airaksinen Anu J, Kaarniranta Kai, Urtti Arto. 2014. Pharmaceutical research. 2015; 32: 211-221 A1 Journal article (refereed), original research -
Oxidative stress plays an important role in zoledronic acid-induced autophagy
Khandelwal VK, Mitrofan LM, Hyttinen JM, Chaudhari KR, Buccione R, Kaarniranta K, Ravingerová T, Mönkkönen J. 2014. Physiological research. 63: S601-S612 A1 Journal article (refereed), original research -
Oxidative stress, hypoxia, and autophagy in the neovascular processes of age-related macular degeneration
Blasiak Janusz, Petrovski Goran, Veréb Zoltan, Facskó Andrea, Kaarniranta Kai. 2014. Journal of biomedicine and biotechnology. 2014: 1-7 A2 Review article, Literature review, Systematic review -
Pinosylvin-mediated protection against oxidative stress in human retinal pigment epithelial cells
Koskela Ali, Reinisalo Mika, Hyttinen Juha MT, Kaarniranta Kai, Karjalainen Reijo O. 2014. Molecular vision. 20: 760-769 A1 Journal article (refereed), original research -
Recovery and patient satisfaction after cataract surgery. A one-year prospective follow-up study
Porela-Tiihonen S, Kaarniranta K, Kokki M, Kokki H. 2014. Acta ophthalmologica. 93: e172-e173 A1 Journal article (refereed), original research -
Silmänpohjan kostea ikärappeuma pitää hoitaa ajoissa
Kinnunen K, Kaarniranta K. 2014. Lääkärilehti. 69: 2265-2268 A2 Review article, Literature review, Systematic review -
Structure and barrier properties of human embryonic stem cell-derived retinal pigment epithelial cells are affected by extracellular matrix protein coating
Sorkio Anni, Hongisto Heidi, Kaarniranta Kai, Uusitalo Hannu, Juuti-Uusitalo Kati, Skottman Heli. 2014. Tissue engineering. 20: 622-634 A1 Journal article (refereed), original research -
Upregulation of inflammatory genes in the nasal mucosa of patients undergoing endonasal dacryocystorhinostomy
Penttilä E, Hyttinen JMT, Hytti M, Kauppinen A, Smirnov G, Tuomilehto H, Seppä J, Nuutinen J, Kaarniranta K. 2014. Clinical ophthalmology. 8: 799-805 A1 Journal article (refereed), original research -
A prospective study on postoperative pain after cataract surgery.
Porela-Tiihonen S, Kaarniranta K, Kokki M, Purhonen S, Kokki H. 2013. Clinical ophthalmology. 7: 1429-1435 A1 Journal article (refereed), original research -
Antagonistic crosstalk between NF-kappaB and SIRT1 in the regulation of inflammation and metabolic disorders
Kauppinen A, Suuronen T, Ojala J, Kaarniranta K, Salminen A. 2013. Cellular signalling. 25: 1939-1948 A2 Review article, Literature review, Systematic review -
Autophagy Activation Clears ELAVL1/HuR-Mediated Accumulation of SQSTM1/p62 during Proteasomal Inhibition in Human Retinal Pigment Epithelial Cells
Viiri J, Amadio M, Marchesi N, Hyttinen JM, Kivinen N, Sironen R, Rilla K, Akhtar S, Provenzani A, D'Agostino VG, Govoni S, Pascale A, Agostini H, Petrovski G, Salminen A, Kaarniranta K. 2013. PLoS ONE. 8: e6963, 16 pages A1 Journal article (refereed), original research -
Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration
Kaarniranta K, Sinha D, Blasiak J, Kauppinen A, Vereb Z, Salminen A, Boulton ME, Petrovski G. 2013. Autophagy. 9: 1-12 A2 Review article, Literature review, Systematic review -
Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: Impact on the aging process
Salminen A, Kaarniranta K, Kauppinen A. 2013. Ageing research reviews. 12: 520-534 A2 Review article, Literature review, Systematic review -
Cellular and molecular mechanisms of age-related macular degeneration: From impaired autophagy to neovascularization
Klettner A, Kauppinen A, Blasiak J, Roider J, Salminen A, Kaarniranta K. 2013. International journal of biochemistry and cell biology. 45: 1457-1467 A2 Review article, Literature review, Systematic review -
Changes in neurophysiologic markers of visual processing following beneficial anti-VEGF treatment in macular degeneration
Vottonen P, Kaarniranta K, Pääkkönen A, Tarkka IM. 2013. Clinical ophthalmology. 7: 437-442 A1 Journal article (refereed), original research -
Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process
Salminen A, Kaarniranta K, Kauppinen A. 2013. International journal of molecular sciences. 14: 3834-3859 A2 Review article, Literature review, Systematic review -
Epigenetic regulation of ASC/TMS1 expression: potential role in apoptosis and inflammasome function
Salminen A, Kauppinen A, Hiltunen M, Kaarniranta K. 2013. Cellular and molecular life sciences. -: - A2 Review article, Literature review, Systematic review -
Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome
Salminen A, Kaarniranta K, Kauppinen A, Ojala J, Haapasalo A, Soininen H, Hiltunen M. 2013. Progress in neurobiology. 106-107: 33-54 A1 Journal article (refereed), original research -
Inflammation as a target of minocycline: special interest in the regulation of inflammasome signaling
Kauppinen A, Salminen A, Kaarniranta K. 2013. Inflammasome. 1: 2-14 A2 Review article, Literature review, Systematic review -
Maturation of autophagosomes and endosomes: A key role for Rab7
Hyttinen JMT, Niittykoski M, Salminen A, Kaarniranta K. 2013. Biochimica et biophysica acta: international journal of biochemistry and biophysics. 1833: 503-510 A1 Journal article (refereed), original research -
Mitochondrial and nuclear DNA damage and repair in age-related macular degeneration
Blasiak J, Glowacki S, Kauppinen A, Kaarniranta K. 2013. International journal of molecular sciences. 14: 2996-3010 A2 Review article, Literature review, Systematic review -
Oxidative DNA Damage and Proteostasis in Age-Related Macular Degeneration
Tokarz P, Kauppinen A, Kaarniranta K, Blasiak J. 2013. Journal of biochemical and pharmacological research. 1: 106-113 A2 Review article, Literature review, Systematic review -
Postoperative pain after cataract surgery
Porela-Tiihonen S, Kaarniranta K, Kokki H. 2013. Journal of cataract and refractive surgery. 39: 789-98 A1 Journal article (refereed), original research -
Potential of epigenetic mechanisms in AMD pathology
Blasiak J, Salminen A, Kaarniranta K. 2013. FRONTIERS IN BIOSCIENCE. 5: 412-425 A1 Journal article (refereed), original research -
Retinal arterial macroaneurysms
Pitkänen L, Tommila P, Kaarniranta K, Jääskeläinen JE, Kinnunen K. 2013. Acta ophthalmologica. 2013: 1-4 A2 Review article, Literature review, Systematic review -
Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD)
Tokarz P, Kaarniranta K, Blasiak J. 2013. Biogerontology. 14: 461-82 A2 Review article, Literature review, Systematic review -
Silmänpohjan kostean ikärappeuman hoito
Kaarniranta K. 2013. Terveydenhoitoviesti. 1: 20 D1 Article in a trade journal -
AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network
Salminen A, Kaarniranta K. 2012. Ageing research reviews. 11: 230-241 A1 Journal article (refereed), original research -
Adiponectin receptor 1 gene (ADIPOR1) variant is associated with advanced age-related macular degeneration in Finnish population
Kaarniranta K, Paananen J, Nevalainen T, Sorri I, Seitsonen S, Immonen I, Salminen A, Pulkkinen L, Uusitupa M. 2012. Neuroscience letters. 513: 233-237 A1 Journal article (refereed), original research -
Aikuisten alakyyneltietukosten kirurginen hoito
Seppä J, Smirnov G, Kaarniranta K, Tuomilehto H. 2012. Duodecim. 128: 205-2011 A1 Journal article (refereed), original research -
Autophagy in the eye: a double-edged sword, (Chapter 8)
Petrovski, G; Albert, R; Kaarniranta, K; Morten, CM; Fésus, L; Berta, A; Das, DK. Teoksessa: Ed. Gorbunov, Nikolai(toim.) , 2012. Autophagy: Principles, Regulation & Roles in Disease.. s. 157-180. Nova science publishers A3 Book section, Chapters in research books -
Autophagy regulating kinases as potential therapeutic targets for age-related macular degeneration
Kaarniranta K, Kauppinen A, Blasiak J, Salminen A. 2012. Future medicinal chemistry. 4: 2153-2161 A2 Review article, Literature review, Systematic review -
Bilberries potentially alleviate stress-related retinal gene expression induced by a high-fat diet in mice
Mykkänen OT, Kalesnykas G, Adriaens M, Evelo CT, Törrönen R, Kaarniranta K. 2012. Molecular vision. 18: 2338-2351 A1 Journal article (refereed), original research -
Context-dependent regulation of autophagy by IKK-NF-kappaB signaling: Impact on the aging process
Salminen A, Hyttinen JMT, Kauppinen A, Kaarniranta K. 2012. International journal of cell biology. 2012: 15 pages A2 Review article, Literature review, Systematic review -
Efflux Protein Expression in Human Stem Cell-Derived Retinal Pigment Epithelial Cells
Juuti-Uusitalo, K; Vaajasaari, H; Ryhänen, T; Narkilahti, S; Suuronen, R; Mannermaa, E; Kaarniranta, K; Skottman, H. 2012. PLoS ONE. 7: 1-10 A1 Journal article (refereed), original research -
Emerging role of NF-kappaB signaling in the induction of senescence-associated secretory phenotype (SASP)
Salminen A, Kauppinen A, Kaarniranta K. 2012. Cellular signalling. 24: 835-845 A2 Review article, Literature review, Systematic review -
Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease
Salminen, A; Kaarniranta, K; Haapasalo, A; Hiltunen, M; Soininen, H; Alafuzoff, I. 2012. Progress in neurobiology. 96: 87-95 A1 Journal article (refereed), original research -
Fibrillin-2, tenascin-C, matrilin-2, and matrilin-4 are strongly expressed in the epithelium of human granular and lattice type I corneal dystrophies
Szalai, E; Felszeghy, S; Hegyi, Z; Módis, L Jr; Berta, A; Kaarniranta, K. 2012. Molecular vision. 18: 1927-1936 A1 Journal article (refereed), original research -
Genetic Variability in DNA Repair Proteins in Age-Related Macular Degeneration
Blasiak, J; Synowiec, E; Salminen, A; Kaarniranta, K. 2012. International journal of molecular sciences. 13: 13378-13379 A2 Review article, Literature review, Systematic review -
Guidelines for the use and interpretation of assays for monitoring autophagy
Klionsky, DJ, Abdalla, FC; Abeliovich, H; Abraham, RT; Acevedo-Arozena, A; Adeli, K; Agholme, L; Agnello, M; Agostinis, P; Aguirre-Ghiso, JA; Ait-Mohamed, O; Ait-Si-Ali, S; Akematsu, T; Akira, S; Al-Younes, HM; Al-Zeer, MA; Albert, ML; Albin, RL; Alegre-Abarrategui, J; Kaarniranta, K; et al.. 2012. Autophagy. 8: 445-544 A2 Review article, Literature review, Systematic review -
Inflammaging: disturbed interplay between autophagy and inflammasomes
Salminen, A; Kaarniranta, K; Kauppinen, A. 2012. Aging. 4: 166-175 A1 Journal article (refereed), original research -
Mitochondrial dysfunction and oxidative stress active inflammasomes: impact on the aging process and age-related diseases
Salminen A, Ojala J, Kaarniranta K, Kauppinen A. 2012. Cellular and molecular life sciences. 69: 2999-3013 A1 Journal article (refereed), original research -
Molecular mechanisms of retinal pigment epithelium damage and development of age-related macular degeneration
Kinnunen, K; Petrovski, G; Moe, MC; Berta, A; Kaarniranta, K. 2012. Acta ophthalmologica. 90: 299-309 A2 Review article, Literature review, Systematic review -
Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells - Implications for age-related macular degeneration (AMD)
Kauppinen A, Niskanen H, Suuronen T, Kinnunen K, Salminen A, Kaarniranta K. 2012. Immunology letters. 147: 29-33 A1 Journal article (refereed), original research -
Phytochemicals suppress nuclear factor-kappaB signaling: impact on health span and the aging process
Salminen A, Kauppinen A, Kaarniranta K. 2012. Current opinion in clinical nutrition and metabolic care. 15: 23-28 A2 Review article, Literature review, Systematic review -
Protective function of wood-derived stilbenes against oxidative stress and inflammation in ARPE-19 cells
Mika Reinisalo, Tuomas Paimela, Tuomas Ryhänen, Anu Kauppinen, Ali Koskela, Tuula Soininen, Kai Kaarniranta, Reijo Karjalainen. 2012. -
Protein-oxidized phospholipid interactions in cellular signaling for cell death: From biophysics to clinical correlations
Kinnunen, PK; Kaarniranta, K; Mahalka, AK. 2012. Biochimica et biophysica acta: biomembranes. 1818: 2446-2455 A1 Journal article (refereed), original research -
Relation of biometric eye profile with intraocular pressure corrections in healthy myopes
Pärssinen, O; Hiltunen, H; Kaarniranta, K. 2012. Acta ophthalmologica. 90: e410-412 A1 Journal article (refereed), original research -
Silmänpohjan ikärappeuma yleistyy
Kaarniranta, K. 2012. OPTOMETRIA. 3: 39-41 D1 Article in a trade journal -
The preservative polyquaternium-1 increases cytoxicity and NF-kappaB linked inflammation in human corneal epithelial cells
Paimela, T; Ryhänen, T; Kauppinen, A; Marttila, L; Salminen, A; Kaarniranta, K. 2012. Molecular vision. 18: 1189-1196 A1 Journal article (refereed), original research -
5'-adenosine monophosphate-activated protein kinase-Mammalian target of rapamycin axis as therapeutic target for age-related macular degeneration
Hyttinen JM, Petrovski G, Salminen A, Kaarniranta K. 2011. Rejuvenation research. 14: 651-660 A1 Journal article (refereed), original research -
AMP-activated protein kinase inhibits NF-kappaB signaling and inflammation: impact on healthspan and lifespan
Salminen A, Hyttinen JMT, Kaarniranta K. 2011. Journal of molecular medicine: jmm. 89: 667-676 A2 Review article, Literature review, Systematic review -
AMP-activated protein kinase: a potential player in Alzheimer's disease
Salminen A, Kaarniranta K, Haapasalo A, Soininen H, Hiltunen M. 2011. Journal of neurochemistry. 118: 460-474 A1 Journal article (refereed), original research -
Age-related macular degeneration (AMD): Alzheimer's Disease in the eye
Kaarniranta K, Salminen A, Haapasalo A, Soininen H, Hiltunen M. 2011. Journal of Alzheimer's disease. 24: 615-631 A2 Review article, Literature review, Systematic review -
Apoptosis and aging: increased resistance to apoptosis enhances the aging process
Salminen A, Ojala J, Kaarniranta K. 2011. Cellular and molecular life sciences. 68: 1021-1031 A1 Journal article (refereed), original research -
Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype
Salminen A, Ojala J, Kaarniranta K, Haapasalo A, Hiltunen M, Soininen H. 2011. European journal of neuroscience. 34: 3-11 A2 Review article, Literature review, Systematic review -
Biocompatibility of different poly(lactide-coglycolide) polymers implanted into the subconjunctival space in rats
Seppo Rönkkö, Kai Kaarniranta, Giedrius Kalesnykas, Hannu Uusitalo. 2011. Ophthalmic research. 46: 55-65 A1 Journal article (refereed), original research -
Celastrol regulates innate immunity response via NF-kappaB and Hsp70 in human retinal pigment epithelial cells
Paimela T, Hyttinen JMT, Viiri J, Ryhänen T, Karjalainen RO, Salminen A, Kaarniranta K. 2011. Pharmacological research. 64: 501-508 A1 Journal article (refereed), original research -
Cis-urocanic acid inhibits SAPK/JNK signaling pathway in UV-B exposed human corneal epithelial cells in vitro
Jauhonen H-M, Kauppinen A, Paimela T, Laihia JK, Leino L, Salminen A, Kaarniranta K. 2011. Molecular vision. 17: 2311-2317 A1 Journal article (refereed), original research -
Control of p53 and NF-kB signaling by WIP1 and MIF: Role in cellular senescence and organismal aging
Salminen Antero, Kaarniranta Kai. 2011. Cellular signalling. 23: 747-752 A2 Review article, Literature review, Systematic review -
Emerging role of p62/sequestosome-1 in th pathogenesis of Alzheimer's disease
Salminen A, Kaarniranta K, Haapasalo A, Hiltunen M, Soininen H, Alafuzoff I. 2011. Progress in neurobiology. 96: 87-95 A1 Journal article (refereed), original research -
Increased IL-6 levels are not related to NF-kappaB or HIF-1alfa: transcription factors activity in the vitreous of proliferative diabetic retinopathy
Arjamaa O, Pöllönen M, Kinnunen K, Ryhänen T, Kaarniranta K. 2011. Journal of diabetes and its complications. 25: 393-397 A1 Journal article (refereed), original research -
Mitomycin C in revision endoscopic dacryocystorhinostomy: A prospective randomized study
Penttilä E, Smirnov G, Seppä J, Kaarniranta K, Tuomilehto H. 2011. American journal of rhinology and allergy. 25: 425-428 A1 Journal article (refereed), original research -
Plant flavonol quercetin and isoflavone biochanin-A differentially induce protection against oxidative stress and inflammation in ARPE-cells
Saviranta Niina, Veeroos Laura, Granlund Lars, Hassinen Viivi, Kaarniranta Kai, Karjalainen Reijo. 2011. Food research international. 44: 109-113 A1 Journal article (refereed), original research -
Ravistellun lapsen oireyhtymään liittyvät silmälöydökset
Nevalainen T, Kaarniranta K, Puustjärvi T, Kontkanen M. 2011. Lääkärilehti. 66: 453-455 A2 Review article, Literature review, Systematic review -
Silmänpohjan ikärappeuman hoidossa halvempi on tehokas ja turvallinen
Kaarniranta K. 2011. Lääkärilehti. 22: 1812 A1 Journal article (refereed), original research -
Strong expression of HSP47 in metaplastic nasal mucosa may predict a poor outcome after primary endoscopic dacryocystorhinostomy: a prospective study
Smirnov G, Pirinen R, Tuomilehto H, Seppä J, Teräsvirta M, Uusitalo H, Nuutinen J, Kaarniranta K. 2011. Acta ophthalmologica. 89: e132-e136 A1 Journal article (refereed), original research -
Altered calcium signaling in a experimental model of glaucoma
Niittykoski M, Kalesnykas G, Larsson KP, Kaarniranta K, Åkerman KEO, Uusitalo H. 2010. Investigative ophthalmology and visual science. 51: 6387-6393 A1 Journal article (refereed), original research -
Autophagy - hot topic in AMD
Kaarniranta K. 2010. Acta ophthalmologica. 88: 387-388 A1 Journal article (refereed), original research -
Celastrol: Molecular targets of Thunder God Vine
Salminen A, Lehtonen M, Paimela T & Kaarniranta K. 2010. Biochemical and biophysical research communications. 394: 439 - 442 A2 Review article, Literature review, Systematic review -
ER stress and hormetic regulation of the aging process
Salminen A & Kaarniranta K. 2010. Ageing research reviews. 9: 211-217 A2 Review article, Literature review, Systematic review -
Endoplasmic reticulum stress in age-related macular degeneration: Trigger for neovascularization
Salminen A, Kauppinen A, Hyttinen JMT, Toropainen E & Kaarniranta K. 2010. MOLECULAR MEDICINE TODAY. 16: 535-542 A1 Journal article (refereed), original research -
Filter-cultured ARPE-19 cells as outer blood-retinal barrier model
Mannermaa E, Reinisalo M, Ranta V-P, Vellonen K-S, Kokki H, Saarikko A, Kaarniranta K & Urtti A. 2010. European journal of pharmaceutical sciences. 40: 289-296 A1 Journal article (refereed), original research -
Genetics vs. entrophy: Longevity factors suppress the NF-kB-driven entropic aging process
Salminen A & Kaarniranta K. 2010. Ageing research reviews. 9: 298-314 A2 Review article, Literature review, Systematic review -
Glycolysis Links p53 Function With NF-kB Signaling: Impact on Cancer and Aging Process
Salminen A & Kaarniranta K. 2010. Journal of cellular physiology. 224: 1-6 A2 Review article, Literature review, Systematic review -
Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease
Salminen A, Ojala J, Kaarniranta K, Hiltunen M & Soininen H. 2010. Progress in neurobiology. 93: 99-110 A1 Journal article (refereed), original research -
Influence of Hsp90 and HDAC Inhibition and Tubulin Acetylation on Perinuclear Protein Aggregation in Human Retinal Pigment Epithelial Cells
Ryhänen T, Viiri J, Hyttinen JTM, Uusitalo H, Salminen A & Kaarniranta K. 2010. Journal of biomedicine and biotechnology. 2011;2011;798052. Epub 2010 Oct 24: 1-8 A1 Journal article (refereed), original research -
Influence of selective estrogen receptor modulators on interleukin-6 expression in human retinal pigment epithelial cells (ARPE-19)
Paimela T, Hyttinen JMT, Viiri J, Ryhänen T, Karvonen MK, Unkila M, Uusitalo H, Salminen A & Kaarniranta K. 2010. European journal of pharmacology. 640: 219-225 A1 Journal article (refereed), original research -
Insulin/IGF-1 paradox of aging: Regulation via AKT/IKK/NF-kB signaling
Salminen A & Kaarniranta K. 2010. Cellular signalling. 22: 573-577 A2 Review article, Literature review, Systematic review -
Mechanisms of protein aggregation in the retinal pigment epithelial cells
Kai Kaarniranta, Juha Hyttinen, Tuomas Ryhanen, Johanna Viiri, Tuomas Paimela, Elisa Toropainen, Iiris Sorri & Antero Salminen. 2010. FRONTIERS IN BIOSCIENCE. E2: 1374-1384 A1 Journal article (refereed), original research -
Regression of necrotizing scleritis in Wegener's granulomatosis after infiximab treatment
Kaarniranta K. 2010. Acta ophthalmologica. 88: e96-97 A1 Journal article (refereed), original research -
Switching from a preserved toa preservative-free prostaglandin preparation in topical glaucoma medication
Uusitalo H, Chen E, Pfeiffer N, Brignole-Baudouin F, Kaarniranta K, Leino M, Puska P, Palmgren E, Hamacher T, Hofmann G, Petzold G, Richter U, Riedel T, Winter M & Ropo A. 2010. Acta ophthalmologica. 88: 329-336 A1 Journal article (refereed), original research -
Symptom score questionnaire for nasolacrimal duct obstruction in adults - a novel tool to assess the outcome after endoscopic dacryocystorhinostomy
Smirnov G, Tuomilehto H, Kokki H, Kemppainen T, Kiviniemi V, Nuutinen J, Kaarniranta K & Seppä J. 2010. Rhinology. 48: 446-451 A1 Journal article (refereed), original research -
p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells
Viiri J, Hyttinen JMT, Ryhänen T, Rilla K, Paimela T, Kuusisto E, Siitonen A, Urtti A, Salminen A & Kaarniranta K. 2010. Molecular vision. 16: 1399-1414 A1 Journal article (refereed), original research -
Age-related macular degeneration: activation of innate immunity system via pattern recognition receptors
Kaarniranta K, Salminen A. 2009. Journal of molecular medicine: jmm. 87: 117-123 A2 Review article, Literature review, Systematic review -
Cis-urocanic acid suppresses UV-B-induced interleukin-6 and -8 secretion and cytotoxicity in human corneal and conjunctival epithelial cells in vitro
Viiri J, Jauhonen HM, Kauppinen A, Ryhänen T, Paimela T, Hyttinen J, Sorri I, Laihia JK, Leino L, Kaarniranta K. 2009. Molecular vision. 15: 1799-1805 A1 Journal article (refereed), original research -
ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology
Salminen A, Kauppinen A, Suuronen T, Kaarniranta K, Ojala J. 2009. Journal of neuroinflammation. 6: [13 p.] A2 Review article, Literature review, Systematic review -
Efflux protein expression in human retinal pigment epithelium cell lines
Mannermaa E, Vellonen K-S, Ryhänen T, Kokkonen K, Ranta V-P, Kaarniranta K, Urtti A. 2009. Pharmaceutical research. 26: 1785-1791 A1 Journal article (refereed), original research -
Heat shock proteins as gatekeepers of proteolytic pathways - Implications for age-related macular generation (AMD)
Kaarniranta K, Salminen A, Eskelinen E-L, Kopitz J. 2009. Ageing research reviews. 8: 128-139 A1 Journal article (refereed), original research -
Inflammation in Alzheimer's disease: Amyloid-beta oligomers trigger innate immunity defence via pattern recognition receptors
Salminen A, Ojala J, Kauppinen A, Kaarniranta K, Suuronen T. 2009. Progress in neurobiology. 87: 181-194 A1 Journal article (refereed), original research -
NF-kappaB signaling as a putative target for omega-3 metabolites in the prevention of age-related macular degeneration (AMD)
Kaarniranta K, Salminen A. 2009. Experimental gerontology. 44: 685-688 A1 Journal article (refereed), original research -
NF-kappaB signaling in the aging process
Salminen A, Kaarniranta K. 2009. Journal of clinical immunology. 29: 397-405 A1 Journal article (refereed), original research -
Regulation of the aging process by autophagy
Salminen A, Kaarniranta K. 2009. Trends in molecular medicine. 15: 217-224 A2 Review article, Literature review, Systematic review -
Regulatory role of HIF-1alfa in the pathogenesis of age-related macular degeneration (AMD)
Arjamaa O, Nikinmaa M, Salminen A, Kaarniranta K. 2009. Ageing research reviews. 8: 349-358 A1 Journal article (refereed), original research -
Retinal haemorrhages in shaken baby syndrome
Kontkanen M, Kaarniranta K. 2009. Acta ophthalmologica -
SIRT1 regulates the ribosomal DNA locus: Epigenetic candles twinkle longevity in the Christmas tree
Salminen A, Kaarniranta K. 2009. Biochemical and biophysical research communications. 378: 6-9 A1 Journal article (refereed), original research -
SIRT1: Regulation of longevity via autophagy
Salminen A, Kaarniranta K. 2009. Cellular signalling. 21: 1356-1360 A1 Journal article (refereed), original research -
Siglec receptors and hiding plaques in Alzheimer's disease
Salminen A, Kaarniranta K. 2009. Journal of molecular medicine: jmm. 87: 697-701 A1 Journal article (refereed), original research -
Silmänpohjan ikärappeuman patogeneesi
Kaarniranta K, Seitsonen S, Paimela T, Meri S, Immonen I. 2009. Duodecim. 125: 145-153 A2 Review article, Literature review, Systematic review -
Silmänpohjan ikärappeuman riskitekijät ja hoito
Kaarniranta K, Puustjärvi T, Sorri I. 2009. TERVEYDENHOITOVIESTI, KESKI-SUOMI PIRKANMAA. : s. 16, 29 D1 Article in a trade journal -
Single nucleotide polymorphisms of the tenomodulin gene (TNMD) in age-related macular degeneration
Tolppanen A-M, Nevalainen T, Kolehmainen M, Seitsonen S, Immonen I, Uusitupa M, Kaarniranta K, Pulkkinen L, Tolppanen A-M, Kolehmainen M, Uusitupa M, Pulkkinen L. 2009. Molecular vision. 15: 762-770 A1 Journal article (refereed), original research -
Vääristyvä kuva silmänpohjan ikärappeumassa - kuinka hoidetaan?
Kaarniranta K. 2009. Lääkärilehti. 64: 3759-3763 A1 Journal article (refereed), original research -
Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging
Salminen A, Huuskonen J, Ojala J, Kauppinen A, Kaarniranta K, Suuronen T. 2008. Ageing research reviews. 7: 83-105 A2 Review article, Literature review, Systematic review -
Amyloid-beta oligomers set fire to inflammasomes and induce Alzherimer's pathology
Salminen A, Ojala J, Suuronen T, Kaarniranta K, Kauppinen A. 2008. Journal of cellular and molecular medicine. 12: 2255-2262 A1 Journal article (refereed), original research -
Diabeteksen aiheuttamat silmämuutokset
Kaarniranta K, Sorri I. 2008. Lääkärilehti. 63: 621-624 A2 Review article, Literature review, Systematic review -
Histopathology of the three implanted degradable biopolymers in rabbit eye
Rönkkö S, Rekonen P, Sihvola R, Kaarniranta K, Puustjärvi T, Teräsvirta M, Uusitalo H. 2008. Journal of biomedical materials research part a. 88: 717-724 A1 Journal article (refereed), original research -
In vitro biocompatibility of degradable biopolymers in cell line cultures from various ocular tissues: extraction studies
Huhtala A, Pohjonen T, Salminen L, Salminen A, Kaarniranta K, Uusitalo H. 2008. Journal of materials science: materials in medicine. 19: 645-649 A1 Journal article (refereed), original research -
Innate immunity meets with cellular stress at the IKK complex: Regulation of the IKK complex by HSP70 and HSP90
Salminen A, Paimela T, Suuronen T, Kaarniranta K. 2008. Immunology letters. 117: 9-15 A2 Review article, Literature review, Systematic review -
Interaction of aging-associated signaling cascades: Inhibition of NF-kappaB signaling by longevity factors FoxOs and SIRT1
Salminen A, Ojala J, Huuskonen J, Kauppinen A, Suuronen T, Kaarniranta K. 2008. Cellular and molecular life sciences. 65: 1049-1058 A2 Review article, Literature review, Systematic review -
Multifactor effects and evidence of potential interaction between complement factor H Y402H and LOC387715 A69S in age-related macular degeneration
Seitsonen SP, Onkamo P, Peng G, Xiong M, Tommila PV, Ranta PH, Holopainen JM, Moilanen JA, Palosaari T, Kaarniranta K, Meri S, Immonen IR, Järvelä IE. 2008. PLoS ONE. 3: e3833 A1 Journal article (refereed), original research -
NEMO shuttle: a link between DNA damage and NF-kappaB activation in progeroid syndromes?
Salminen A, Suuronen T, Huuskonen J, Kaarniranta K. 2008. Biochemical and biophysical research communications. 367: 715-718 A2 Review article, Literature review, Systematic review -
Pharmacokinetics, efficacy and safety profiles of preserved and preservative-free tafluprost in healthy volunteers
Uusitalo H, Kaarniranta K, Ropo A. 2008. Acta ophthalmologica. Supplement. 86: 7-13 A1 Journal article (refereed), original research -
ROCK, PAK, and Toll of synapses in Alzheimer's disease
Salminen A, Suuronen T, Kaarniranta K. 2008. Biochemical and biophysical research communications. 371: 587-590 A2 Review article, Literature review, Systematic review -
Radicicol but not geldanamycin evokes oxidative stress response and efflux protein inhibition in ARPE-19 human retinal pigment epithelial cells
Ryhänen T, Mannermaa E, Oksala N, Viiri J, Paimela T, Salminen A, Atalay M, Kaarniranta K. 2008. European journal of pharmacology. 584: 229-236 A1 Journal article (refereed), original research -
Regulation of ERalfa signaling pathway in neuronal HN10 cells: role of protein acetylation and Hsp90
Suuronen T, Ojala J, Hyttinen JMT, Kaarniranta K, Thornell A, Kyrylenko S, Salminen A. 2008. Neurochemical research. 33: 1768-1775 A1 Journal article (refereed), original research -
SIRT1 longevity factor suppresses NF-kappaB -driven immune responses: regulation of aging via NF-kappaB acetylation?
Salminen A, Kauppinen A, Suuronen T, Kaarniranta K. 2008. Bioessays. 30: 939-942 A1 Journal article (refereed), original research -
Terpenoids: natural inhibitors of NF-kappaB signaling with anti-inflammatory and anticancer potential
Salminen A, Lehtonen M, Suuronen T, Kaarniranta K, Huuskonen J. 2008. Cellular and molecular life sciences. 65: 2979-2999 A2 Review article, Literature review, Systematic review -
Alpha-lipoic acid modulates heat shock factor-1 expression in streptozotocin-induced diabetic rat kidney
Oksala NKJ, Lappalainen J, Laaksonen DE, Khanna S, Kaarniranta K, Sen CK, Atalay M. 2007. Antioxidants and redox signaling. 9: 497-506 A1 Journal article (refereed), original research -
Corneal epithelium as a platform for secretion of transgene products after transfection with liposomal gene eyedrops
Toropainen E, Hornof M, Kaarniranta K, Johansson P, Urtti A. 2007. Journal of gene medicine. 9: 208-216 A1 Journal article (refereed), original research -
Epigenetic regulation of clusterin/apolipoprotein J expression in retinal pigment epithelial cells
Suuronen T, Nuutinen T, Ryhänen T, Kaarniranta K, Salminen A. 2007. Biochemical and biophysical research communications. 357: 397-401 A1 Journal article (refereed), original research -
Imiquimod in the treatment of eyelid basal cell carcinoma
Leppälä J, Kaarniranta K, Uusitalo H, Kontkanen M. 2007. Acta ophthalmologica. 85: 566-568 A1 Journal article (refereed), original research -
In vitro biocompatibility of degradable biopolymers in cell line cultures from various ocular tissues:Direct contact studies
Huhtala A, Pohjonen T, Salminen L, Salminen A, Kaarniranta K, Uusitalo H. 2007. Journal of biomedical materials research part a. 83A: 407-413 A1 Journal article (refereed), original research -
Leucine 7-proline 7 polymorphism in the signal peptide of neuropeptide Y is not a risk factor for exudative age-related macular degeneration
Kaarniranta K, Holopainen JM , Karvonen MK, Koulu M, Kallio J, Pesonen U, Teräsvirta M, Uusitalo H, Immonen I. 2007. Acta ophthalmologica. 85: 188-191 A1 Journal article (refereed), original research -
Maculopathy in Pierre Robin sequences
Kaarniranta K, Tuppurainen K, Nikolajev K. 2007. Journal of pediatric ophthalmology and strabismus -
Matrix metalloproteinases and their inhibitors in the chamber angle of normal eyes and patients with primary open-angle glaucoma and exfoliation glaucoma
Rönkkö S, Rekonen P, Kaarniranta K, Puustjärvi T, Teräsvirta M, Uusitalo M. 2007. Graefes archive for clinical and experimental ophthalmology. 245: 697-704 A1 Journal article (refereed), original research -
Phospholipase A2 in chamber angle of normal eyes and patients with primary open angle glaucoma and exfoliation glaucoma
Rönkkö S, Rekonen P, Kaarniranta K, Puustjärvi T, Teräsvirta M, Uusitalo H. 2007. Molecular vision. 13: 408-417 A1 Journal article (refereed), original research -
Silmänpohjan nesteisen ikärappeuman uudet lääkkeet
Mannermaa E, Urtti A, Kaarniranta K. 2007. Duodecim. 123: 2229-2237 A2 Review article, Literature review, Systematic review -
The effect of 17beta-estradiol on IL-6 secretion and NF-kappaB DNA-binding activity in human retinal pigment epithelial cells
Paimela T, Ryhänen T, Mannermaa E, Ojala J, Kalesnykas G, Salminen A, Kaarniranta K, Ojala J. 2007. Immunology letters. 110: 139-144 A1 Journal article (refereed), original research -
The expression of heat shock protein 27 in retinal ganglion and glial cells in a rat glaucoma model
Kalesnykas G, Niittykoski M, Rantala J, Miettinen R, Salminen A, Kaarniranta K, Uusitalo H. 2007. Neuroscience. 150: 692-704 A1 Journal article (refereed), original research -
A mouse model for Stickler's syndrome: Ocular phenotype of mice carrying a targeted heterozygous inactivation of type II (pro)collagen gene (Col2al)
Kaarniranta K, Ihanamäki T, Sahlman J, Pulkkinen H, Uusitalo H, Arita M, Tammi R, Lammi MJ, Helminen H. 2006. Experimental eye research. 83: 297-303 A1 Journal article (refereed), original research -
Analysis of variants in the complement factor H, the elongation of very long chain fatty acids-like 4 and the hemicentin 1 genes of age-related macular degeneration in the Finnish population
Seitsonen S, Lemmelä S, Holopainen J, Tommila P, Ranta P, Kotamies A, Moilanen J, Palosaari T, Kaarniranta K, Meri S, Immonen I, Järvelä I. 2006. Molecular vision. 12: 796-801 A1 Journal article (refereed), original research -
Immunolocalization of EMMPRIN (Cd147) in the human eye and detection of soluble form of EMMPRIN in ocular fluids
Määttä M, Tervahartiala T, Kaarniranta K, Tang Y, Yan L, Tuukkanen J, Sorsa T. 2006. Current eye research. 31: 917-924 A1 Journal article (refereed), original research -
Geldanamycin activates Hsp70 response and attenuates okadaic acid-induced cytotoxicity in human retinal pigment epithelial cells
Kaarniranta K, Ryhänen T, Sironen RK, Suuronen T, Elo MA, Karjalainen HM, Lammi MJ, Teräsvirta M, Uusitalo H, Salminen A. 2005. MOLECULAR BRAIN RESEARCH. 137: 126-131 A1 Journal article (refereed), original research -
Geldanamycin increases 4-hydroxynonenal (HNE)-induced cell death in human retinal pigment epithelial cells
Kaarniranta K, Ryhänen T, Karjalainen HM, Lammi MJ, Suuronen T, Huhtala A, Kontkanen M, Teräsvirta M, Uusitalo H, Salminen A. 2005. Neuroscience letters. 382: 185-190 A1 Journal article (refereed), original research -
Hsp90 inhibitor geldanamycin increases hsp70 mRNA stabilisation but fails to activate HSF1 in cells exposed to hydrostatic pressure
Elo MA, Kaarniranta K, Helminen HJ, Lammi MJ. 2005. Biochimica et biophysica acta: molecular cell research. 1743: 115-119 A1 Journal article (refereed), original research -
Solustressi yhdistyy silmänpohjan ikärappeumaan
Kaarniranta K. 2005. SILMÄHOITAJA. : 4-5 D1 Article in a trade journal -
Hydrostatic pressure-induced changes in cellular protein syntheisis
Lammi MJ, Elo MA, Sironen RK, Karjalainen HM, Kaarniranta K, Helminen HJ. 2004. Biorheology. 41: 309-313 A1 Journal article (refereed), original research -
Gene expression profiles in chondrosarcoma cells subjected to cyclic stretching and hydrostatic pressure. A cDNA array study
Karjalainen HM, Sironen RK, Elo MA, Kaarniranta K, Takigawa M, Helminen HJ, Lammi MJ. 2003. Biorheology. 40: 93-100 A1 Journal article (refereed), original research -
Silmänpohjan ikärappeuma - vaikea ongelma sekä potilaalle että silmälääkärille
Kaarniranta K, Sihvola R, Salminen A, Lammi MJ, Teräsvirta M, Kontkanen M. 2003. Duodecim. 119: 935-942 A2 Review article, Literature review, Systematic review -
Specific induction of heat shock protein 90 beta by high hydrostatic pressure
Elo MA, Sironen RK, Karjalainen HM, Kaarniranta K, Helminen HJ, Lammi MJ. 2003. Biorheology. 40: 141-146 A1 Journal article (refereed), original research -
Stress responses of mammalian cells to high hydrostatic pressure
Kaarniranta K, Elo MA, Sironen RK, Karjalainen HM, Helminen HJ, Lammi MJ. 2003. Biorheology. 40: 87-92 A1 Journal article (refereed), original research -
High pressure effects on cellular expression profile and mRNA stability. A cDNA array analysis
Sironen RK, Karjalainen HM, Törrönen K, Elo MA, Kaarniranta K, Takigawa M, Helminen HJ, Lammi MJ. 2002. Biorheology. 39: 111-117 A1 Journal article (refereed), original research -
Hyaluronan stimulates keratinocyte migration and activates the transcription factor AP-1 in keratinocytes through the JNK pathway
Törrönen K, Yabal M, Rilla K, Kaarniranta K, Tammi R, Lammi MJ, Tammi M. Teoksessa: Kennedy JF, Phillips GO, Williams PA, Hascall VC(toim.) , 2002. Hyaluronan. Chemical, Biochemical and Biological Aspects.. s. 551-556. Woodhead A3 Book section, Chapters in research books -
Neuronal cells show regulatory differences in the hsp70 gene response
Kaarniranta K, Oksala N, Karjalainen HM, Suuronen T, Sistonen L, Helminen HJ, Salminen A, Lammi MJ. 2002. MOLECULAR BRAIN RESEARCH. 101: 136-140 A1 Journal article (refereed), original research -
Regulatory Differences of the hsp70 Gene Response in Mammalian Cells
Kaarniranta K. 2002. Kuopio University Publications D. Medical Sciences G5 Doctoral dissertation (article) -
cDNA array reveals mechanosensitive genes in chondrocytic cells under hydrostatic pressure
Sironen RK, Karjalainen HM, Elo MA, Kaarniranta K, Törrönen K, Takigawa M, Helminen HJ, Lammi MJ. 2002. Biochimica et biophysica acta: molecular cell research. 1591: 45-54 A1 Journal article (refereed), original research -
Primary chondrocytes resist hydrostatic pressure-induced stress while primary synovial cells and fibroblasts show modified Hsp70 response
Kaarniranta K, Holmberg CI, Lammi MJ, Eriksson JE, Sistonen L, Helminen HJ. 2001. Osteoarthritis and cartilage. 9: 7-13 A1 Journal article (refereed), original research -
Responses of mammalian cells to mechanical forces
Lammi MJ, Sironen RK, Elo MA, Oksala N, Kaarniranta K, Karjalainen HM, Helminen HJ. Teoksessa: Pandalai SG(toim.) , 2001. Recent Research Developments in Biophysics and Biochemistry. s. 77-98. Research Signpost A3 Book section, Chapters in research books -
Solustressin tutkimuksesta kliinisiin läpimurtoihin?
Kaarniranta K, Oksala N, Lammi MJ, Helminen HJ, Sistonen L. 2001. Duodecim. 117: 2266-2272 A2 Review article, Literature review, Systematic review -
Differential regulation of stress proteins by high hydrostatic pressure, heat shock, and unbalanced calcium homeostasis in chondrocytis cells
Elo MA, Sironen RK, Kaarniranta K, Auriola S, Helminen HJ, Lammi MJ. 2000. Journal of cellular biochemistry. 79: 610-619 A1 Journal article (refereed), original research -
Protein synthesis is required for stabilization of hsp70 mRNA upon exposure to both hydrostatic pressurization and elevated temperature
Kaarniranta K, Holmberg CI, Helminen HJ, Eriksson JE, Sistonen L, Lammi MJ. 2000. Febs letters. 475: 283-286 A1 Journal article (refereed), original research -
Transcriptional activation in chondrocytes submitted to hydrostatic pressure
Sironen R, Elo M, Kaarniranta K, Helminen HJ, Lammi MJ. 2000. Biorheology. 37: 85-93 A1 Journal article (refereed), original research -
Cytoskeleton and proteoglycan synthesis in chondrocytes under hydrostatic pressure
Parkkinen JJ, Lammi MJ, Jortikka MO, Inkinen RI, Kaarniranta K, Helminen HJ, Tammi MI. Teoksessa: Tanaka S, Hamanishi C(toim.) , 1999. Advances in Osteoarthritis. s. 21-34. Springer A3 Book section, Chapters in research books -
Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation
Kaarniranta K, Elo M, Sironen R, Lammi MJ, Goldring MB, Eriksson JE, Sistonen L, Helminen HJ. 1998. Proceedings of the National Academy of Sciences of the United States of America. 95: 2319-2324 A1 Journal article (refereed), original research -
Stage-specific expression and cellular localization of the heat shock factor 2 isoforms in the rat seminiferous epithelium
Alastalo T-P, Lönnström M, Leppä S, Kaarniranta K, Pelto-Huikko M, Sistonen L, Parvinen M. 1998. Experimental cell research. 240: 16-27 A1 Journal article (refereed), original research