Kaisa Paldanius
Coordinator
Coordinator, Brain Research Unit. Responsibilities include coordination of Brain Research Unit ac...
Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences
[email protected] | +358 50 439 2580
Kaisa Paldanius is a Doctor of Philosophy (biochemistry, molecular neurobiology) who is the scientific coordinator of international EU-funded research projects on ageing and dementia risk prevention: AD-RIDDLE, Prominent and 2D-BioPAD. Kaisa has over 20 years of experience in academic research as well as preclinical phase research in a global CRO company. She utilizes these skills in a variety of development and communication tasks at the Brain Research Unit.
Research groups
Publications
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Effects of Alzheimer's Disease-Associated Risk Loci on Cerebrospinal Fluid Biomarkers and Disease Progression: A Polygenic Risk Score Approach
Martiskainen Henna, Helisalmi Seppo, Viswanathan Jayashree, Kurki Mitja, Hall Anette, Herukka Sanna-Kaisa, Sarajärvi Timo, Natunen Teemu, Kurkinen Kaisa M.A., Huovinen Jaakko, Mäkinen Petra, Laitinen Marjo, Koivisto Anne M., Mattila Kari M., Lehtimäki Terho, Remes Anne M., Leinonen Ville, Haapasalo Annakaisa, Soininen Hilkka, Hiltunen Mikko, 2015, Journal of Alzheimer's disease, 43, 2, 565-573. A1 Journal article (refereed), original research -
Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models
Natunen Teemu, Takalo Mari, Kemppainen Ssusanna, Leskelä Stina, Marttinen Mikael, Kurkinen Kaisa MA, Pursiheimo Juha-Pekka, Sarajärvi Timo, Viswanathan Jayashree, Gabbouj Sami, Solje Eino, Tahvanainen Eveliina, Pirttimäki Tiina, Kurki Mitja, Paananen Jussi, Rauramaa Tuomas, Miettinen Pasi, Mäkinen Petra, Leinonen Ville, Soininen Hilkka et al, 2015, Neurobiology of disease, 2016; 85, 187-205. A1 Journal article (refereed), original research -
Synaptic dysfunction and septin protein family members in neurodegenerative diseases
Marttinen Mikael, Kurkinen Kaisa MA, Soininen Hilkka, Haapasalo Annakaisa, Hiltunen Mikko, 2015, Molecular neurodegeneration, 10, 16, 12 p. A2 Review article, Literature review, Systematic review -
High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status
Takalo M, Haapasalo A, Martiskainen H, Kurkinen KM, Koivisto H, Miettinen P, Khandelwal VK, Kemppainen S, Kaminska D, Mäkinen P, Leinonen V, Pihlajamäki J, Soininen H, Laakso M, Tanila H, Hiltunen M, 2014, Journal of nutritional biochemistry, 25, 6, 634-641. A1 Journal article (refereed), original research -
Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models
Martiskainen H, Viswanathan J, Nykänen NP, Kurki M, Helisalmi S, Natunen T, Sarajärvi T, Kurkinen KM, Pursiheimo JP, Rauramaa T, Alafuzoff I, Jääskeläinen JE, Leinonen V, Soininen H, Haapasalo A, Huttunen HJ, Hiltunen M, 2014, Neurobiology of aging, 36, 2, 1221.e15-1221.e28. A1 Journal article (refereed), original research -
Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's Disease
Natunen T, Parrado AR, Helisalmi S, Pursiheimo J-P, Sarajärvi T, Mäkinen P, Kurkinen KMA, Mullin K, Alafuzoff I, Haapasalo A, Bertram L, Soininen H, Tanzi RE, Hiltunen M, 2013, Journal of Alzheimer's disease, 37, 217-232. A1 Journal article (refereed), original research -
Targeting ApoE4/ApoE receptor LRP1 in Alzheimer's disease
Martiskainen H, Haapasalo A, Kurkinen KM, Pihlajamäki J, Soininen H, Hiltunen M, 2013, Expert opinion on therapeutic targets, 17, 7, 781-794. A1 Journal article (refereed), original research -
Targeting ubiquilin-1 in Alzheimer's disease
Takalo M, Haapasalo A, Natunen T, Viswanathan J, Kurkinen KMA, Tanzi RE, Soininen H, Hiltunen M, 2013, Expert opinion on therapeutic targets, 17, 7, 795-810. A2 Review article, Literature review, Systematic review -
Ubiquilin-1 modulates gamma-secretase-mediated epsilon-site cleavage in neuronal cells
Viswanathan J, Haapasalo A, Kurkinen KMA, Natunen T, Mäkinen P, Bertram L, Soininen H, Tanzi RE, Hiltunen M, 2013, Biochemistry, 52, 3899-3912. A1 Journal article (refereed), original research -
Prevention of NMDA-induced death of cortical neurons by inhibition of protein kinase Czeta
Koponen S, Kurkinen K, Åkerman KEO, Mochly-Rosen D, Chan PH, Koistinaho J, 2003, Journal of neurochemistry, 86, 442-450. A1 Journal article (refereed), original research