Maria-Viola Martikainen
Visiting Researcher
Team: Immunotoxicology of environmental exposures
Department of Environmental and Biological Sciences, Faculty of Science, Forestry and Technology
Investigating how different environmental exposures (pollen, farming, air pollution, birth factors) affect respiratory health. I focus on how exposures during prenatal period and early life affect immune responses.
Sample materials include i.e. primary blood human cells, co-cultures of secondary cell lines and primary human bronchial epithelial cells (NHBE).
Research methods include flow cytometric analysis, cytokine analysis using MSD multiplexed ELISA and traditional ELISA and several toxicological assays (MTT, PI, and DCF). Some experience of transepithelial electrical resistance assay, Bradford assay and RNA extraction.
Collaboration with several national and international research groups.
Research groups
Publications
21/21 items-
50 Hz magnetic field influences caspase-3 activity and cell cycle distribution in ionizing radiation exposed SH-SY5Y neuroblastoma cells
Nieminen, Valtteri; Martikainen, Maria-Viola; Kalliomäki, Saija; Virén, Tuomas; Seppälä, Jan; Juutilainen, Jukka; Naarala, Jonne; Luukkonen, Jukka. 2024. International journal of radiation biology. 100: 1183-1192 A1 Journal article (refereed), original research -
Effects of fuel composition and vehicle operating temperature on in vitro toxicity of exhaust emissions
Hakkarainen, Henri; Järvinen, Anssi; Lepistö, Teemu; Kuittinen, Niina; Markkula, Lassi; Ihantola, Tuukka; Yang, Mo; Martikainen, Maria Viola; Mikkonen, Santtu; Timonen, Hilkka; Aurela, Minna; Barreira, Luis; Ihalainen, Mika; Saarikoski, Sanna; Rönkkö, Topi; Aakko-Saksa, Päivi; Jalava, Pasi. 2024. Environmental science : atmospheres. 4: 455-467 A1 Journal article (refereed), original research -
Impact of rising CO2 and temperature on grass phenology, physiology, and pollen release patterns in northern latitudes
Tossavainen, Tarleena; Kivimäenpää, Minna; Martikainen, Maria Viola; Leskinen, Ari; Heinonen, Tiina; Pessi, Anna Mari; Louna-Korteniemi, Maria; Pätsi, Sanna; Komppula, Mika; Saarto, Annika; Roponen, Marjut. 2024. Environmental and experimental botany. 228: . 105995 A1 Journal article (refereed), original research -
Cattle farm dust alters cytokine levels in human airway construct model
Martikainen, Maria-Viola; Huttunen, Kati; Tossavainen, Tarleena; Nordberg, Maria-Elisa; Roponen, Marjut. 2023. Toxicology in vitro. 88: A1 Journal article (refereed), original research -
Common Pollen Modulate Immune Responses against Viral-Like Challenges in Airway Coculture Model
Tossavainen, Tarleena; Martikainen, Maria-Viola; Loukola, Hanna; Roponen, Marjut. 2023. Journal of immunology research. 2023: A1 Journal article (refereed), original research -
Toxicity of exhaust emissions from high aromatic and non-aromatic diesel fuels using in vitro ALI exposure system
Hakkarainen, Henri; Järvinen, Anssi; Lepistö, Teemu; Salo, Laura; Kuittinen, Niina; Laakkonen, Elmeri; Yang, Mo; Martikainen, Maria-Viola; Saarikoski, Sanna; Aurela, Minna; Barreira, Luis; Teinilä, Kimmo; Ihalainen, Mika; Päivi-Aakko-Saksa; Timonen, Hilkka; Rönkkö, Topi; Jalava, Pasi. 2023. Science of the total environment. 890: A1 Journal article (refereed), original research -
Pollen, respiratory viruses, and climate change: Synergistic effects on human health
Martikainen, Maria-Viola; Tossavainen, Tarleena; Hannukka, Noora; Roponen, Marjut. 2022. Environmental research. 2023; 219: A2 Review article, Literature review, Systematic review -
TUBE Project: Transport-Derived Ultrafines and the Brain Effects
Martikainen, Maria-Viola; Aakko-Saksa, Päivi; van den Broek, Lenie; Cassee, Flemming R; Carare, Roxana O; Chew, Sweelin; Dinnyes, Andras; Giugno, Rosalba; Kanninen, Katja M; Malm, Tarja; Muala, Ala; Nedergaard, Maiken; Oudin, Anna; Oyola, Pedro; Pfeiffer, Tobias V; Rönkkö, Topi; Saarikoski, Sanna; Sandström, Thomas; Schins, Roel PF; Topinka, Jan; Yang, Mo; Zeng, Xiaowen; Westerink, Remco HS; Jalava, Pasi I. 2022. International journal of environmental research and public health. 19: A1 Journal article (refereed), original research -
Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles
Liu, Lizhi; Bai, Xuan; Martikainen, Maria-Viola; Kårlund, Anna; Roponen, Marjut; Xu, Wujun; Hu, Guoqing; Tasciotti, Ennio; Lehto, Vesa-Pekka. 2021. Nature communications. 12: 5726 A1 Journal article (refereed), original research -
Genotoxic and inflammatory effects of spruce and brown coal briquettes combustion aerosols on lung cells at the air-liquid interface
Ihantola, Tuukka; Hirvonen, Maija-Riitta; Ihalainen, Mika; Hakkarainen, Henri; Sippula, Olli; Tissari, Jarkko; Bauer, Stefanie; Di Bucchianico, Sebastiano; Rastak, Narges; Hartikainen, Anni; Leskinen, Jani; Yli-Pirilä, Pasi; Martikainen, Maria-Viola; Miettinen, Mirella; Suhonen, Heikki; Rönkkö, Teemu J.; Kortelainen, Miika; Lamberg, Heikki; Czech, Hendryk; Martens, Patrick et al. [incl. Jokiniemi, Jorma; Jalava, Pasi]. 2021. Science of the total environment. 2022; 806: 150489 A1 Journal article (refereed), original research