Mette Heiskanen - UEFConnect

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Information Publications

Research groups

Epilepsy Research

Keywords

biomarkers epilepsy extracellular vesicles microRNA plasma traumatic brain injury (TBI)

Publications

14/14 items

Brain abscess – A rare confounding factor for diagnosis of post-traumatic epilepsy after lateral fluid-percussion injury
Kyyriäinen, Jenni; Andrade, Pedro; Ekolle Ndode-Ekane, Xavier; Manninen, Eppu; Hämäläinen, Elina; Rauramaa, Tuomas; Heiskanen, Mette; Puhakka, Noora; Immonen, Riikka; Pitkänen, Asla. 2024. Epilepsy research. 200: A1 Journal article (refereed), original research
Circulating plasma microRNAs and neurofilament light chain as biomarkers for injury severity and post-traumatic epileptogenesis following an experimental traumatic brain injury
Heiskanen, Mette. 2024. Publications of the University of Eastern Finland. Dissertations in Health Sciences G5 Doctoral dissertation (article)
Plasma microRNAs as prognostic biomarkers for development of severe epilepsy after experimental traumatic brain injury —EpiBioS4Rx Project 1 study
Heiskanen, Mette; Ndode‐Ekane, Xavier Ekolle; Ali, Idrish; Santana‐Gomez, Cesar; Puhakka, Noora; Gupta, Shalini Das; Andrade, Pedro; Immonen, Riikka; Casillas‐Espinosa, Pablo; Manninen, Eppu; Smith, Gregory; Brady, Rhys D.; Silva, Juliana; Braine, Emma; Hudson, Matt; Yamakawa, Glen R.; Jones, Nigel C.; Shultz, Sandy R.; Harris, Neil G.; Wright, David K.; Gröhn, Olli; Staba, Richard J.; O'Brien, Terence J.; Pitkänen, Asla. 2024. Epilepsia. [First published: 11 December 2024]: 1-16 A1 Journal article (refereed), original research
Plasma neurofilament heavy chain is a prognostic biomarker for the development of severe epilepsy after experimental traumatic brain injury
Heiskanen, Mette; Banuelos, Ivette; Manninen, Eppu; Andrade, Pedro; Hämäläinen, Elina; Puhakka, Noora; Pitkänen, Asla. 2024. Epilepsia. 65: 3703-3716 A1 Journal article (refereed), original research
Discovery and Validation of Circulating microRNAs as Biomarkers for Epileptogenesis after Experimental Traumatic Brain Injury–The EPITARGET Cohort
Heiskanen, Mette; Das Gupta, Shalini; Mills, James D; van Vliet, Erwin A; Manninen, Eppu; Ciszek, Robert; Andrade, Pedro; Puhakka, Noora; Aronica, Eleonora; Pitkänen, Asla. 2023. International journal of molecular sciences. 24: A1 Journal article (refereed), original research
Image data harmonization tools for the analysis of post-traumatic epilepsy development in preclinical multisite MRI studies
Bhagavatula, Sweta; Cabeen, Ryan; Harris, Neil G.; Gröhn, Olli; Wright, David K.; Garner, Rachael; Bennett, Alexis; Alba, Celina; Martinez, Aubrey; Ndode-Ekane, Xavier Ekolle; Andrade, Pedro; Paananen, Tomi; Ciszek, Robert; Immonen, Riikka; Manninen, Eppu; Puhakka, Noora; Tohka, Jussi; Heiskanen, Mette; Ali, Idrish; Shultz, Sandy R.; Casillas-Espinosa, Pablo M.; Yamakawa, Glenn R.; Jones, Nigel C.; Hudson, Matthew R.; Silva, Juliana C.; Braine, Emma L.; Brady, Rhys D.; Santana-Gomez, Cesar E.; S. 2023. Epilepsy research. 195: A1 Journal article (refereed), original research
Proteomics of Deep Cervical Lymph Nodes After Experimental Traumatic Brain Injury
Puhakka, Noora; Das Gupta, Shalini; Leskinen, Sara; Heiskanen, Mette; Nattinen, Janika; Aapola, Ulla; Uusitalo, Hannu; Pitkanen, Asla. 2023. Neurotrauma reports. 4: 359-366 A1 Journal article (refereed), original research
Effect of cell culture media on extracellular vesicle secretion from mesenchymal stromal cells and neurons
Karttunen, Jenni; Heiskanen, Mette; Joki, Tiina; Hyysalo, Anu; Navarro-Ferrandis, Vicente; Miettinen, Susanna; Narkilahti, Susanna; Pitkänen, Asla. 2022. European journal of cell biology. 101: A1 Journal article (refereed), original research
Plasma Neurofilament Light Chain (NF-L) Is a Prognostic Biomarker for Cortical Damage Evolution but Not for Cognitive Impairment or Epileptogenesis Following Experimental TBI
Heiskanen, Mette; Jääskeläinen, Olli; Manninen, Eppu; Das Gupta, Shalini; Andrade, Pedro; Ciszek, Robert; Gröhn, Olli; Herukka, Sanna-Kaisa; Puhakka, Noora; Pitkänen, Asla. 2022. International journal of molecular sciences. 23: A1 Journal article (refereed), original research
Biomarkers for posttraumatic epilepsy
Pitkänen, Asla; Paananen, Tomi; Kyyriäinen, Jenni; Das Gupta, Shalini; Heiskanen, Mette; Vuokila, Niina; Bañuelos-Cabrera, Ivette; Lapinlampi, Niina; Kajevu, Natallie; Andrade, Pedro; Ciszek, Robert; Lara-Valderrábano, Leonardo; Ekolle Ndode-Ekane, Xavier; Puhakka, Noora. 2021. Epilepsy and behavior. 121: 107080 A2 Review article, Literature review, Systematic review
Plasma miR-9-3p and miR-136-3p as Potential Novel Diagnostic Biomarkers for Experimental and Human Mild Traumatic Brain Injury
Das Gupta, Shalini; Ciszek, Robert; Heiskanen, Mette; Lapinlampi, Niina; Kukkonen, Janne; Leinonen, Ville; Puhakka, Noora; Pitkänen, Asla. 2021. International journal of molecular sciences. 22: 1563 A1 Journal article (refereed), original research
Increased expression of miR142 and miR155 in glial and immune cells after traumatic brain injury may contribute to neuroinflammation via astrocyte activation
Korotkov, Anatoly; Puhakka, Noora; Gupta, Shalini Das; Vuokila, Niina; Broekaart, Diede W M; Anink, Jasper J; Heiskanen, Mette; Karttunen, Jenni; van Scheppingen, Jackelien; Huitinga, Inge; Mills, James D; van Vliet, Erwin A; Pitkänen, Asla; Aronica, Eleonora. 2020. Brain pathology. 30: 897-912 A1 Journal article (refereed), original research
Extracellular Vesicles as Diagnostics and Therapeutics for Structural Epilepsies
Karttunen, J; Heiskanen, M; Lipponen, A; Poulsen, D; Pitkänen, A. 2019. International journal of molecular sciences. 20: 1259 A2 Review article, Literature review, Systematic review
Precipitation-based extracellular vesicle isolation from rat plasma co-precipitate vesicle-free microRNAs
Karttunen, Jenni; Heiskanen, Mette; Navarro-Ferrandis, Vicente; Das Gupta, Shalini; Lipponen, Anssi; Puhakka, Noora; Rilla, Kirsi; Koistinen, Arto; Pitkänen, Asla. 2018. Journal of extracellular vesicles. 2019; 8: 1555410 A1 Journal article (refereed), original research