Multiscale Imaging Group
Research group
                                    
                         01.09.2015 -                     
                                    
                                A.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences                            
                                            Leaders
Contact persons
The multiscale imaging group is a multidisciplinary team interested in the application, combination and development of imaging modalities focused in brain at several scales. Our greatest interest is the study of the structure of the healthy and diseased brain from the macro- and microscale with non-invasive techniques to the nanoscale with microscopy techniques in combination with image processing, data analyses and tissue modelling.
Keywords
                                                            3D electron microscopy
                                                            animal models
                                                            biomarkers
                                                            brain
                                                            brain injury
                                                            demyelination
                                                            diffusion MRI
                                                            diffusion tensor imaging
                                                            fourier analysis
                                                            high angular resolution diffusion imaging
                                                            histology
                                                            imaging
                                                            inflammation
                                                            microimaging
                                                            microstructure
                                                            montecarlo simulations
                                                            neurodegeneration
                                                            orientation distribution function
                                                            plasticity
                                                            segmentation
                                                            serial block face scanning electron microscopy
                                                            structure tensor
                                                    
                                    Leaders
Post-doctoral Researchers
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                        Jenni Kyyriäinen
Project ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences - 
        
                            
                        
Raimo Salo
Project ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences - 
        
                            
                        
Juan Valverde Martínez
Visiting ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences - 
        
                            
                        
Maxime Yon
Visiting ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences 
Doctoral Researchers
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                        Omar Narvaez Delgado
Doctoral ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences - 
        
                            
                        Melina Estela Dalmau
Doctoral ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences - 
        
                            
                        
Mohammad Khateri
Doctoral ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences - 
        
                            
                        
Sara Gröhn
Doctoral ResearcherA.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences 
Technicians
Contact persons
Visiting Scientist
Publications
10 items- 
                                            
                                                
Advanced microscopic validation of diffusion MRI in rat brain
Salo, Raimo, 2021, Publications of the University of Eastern Finland. Dissertations in Health Sciences. G5 Doctoral dissertation (article) - 
                                            
                                                
Automated 3D segmentation and morphometry of white matter ultrastructures
Abdollahzadeh, Ali, 2021, Publications of the University of Eastern Finland. Dissertations in Health Sciences. G5 Doctoral dissertation (article) - 
                                            
                                                
Cylindrical Shape Decomposition for 3D Segmentation of Tubular Objects
Abdollahzadeh, Ali; Sierra, Alejandra; Tohka, Jussi, 2021, IEEE access, 9, 23979-23995. A1 Journal article (refereed), original research - 
                                            
                                                
DeepACSON automated segmentation of white matter in 3D electron microscopy
Abdollahzadeh, Ali; Belevich, Ilya; Jokitalo, Eija; Sierra, Alejandra; Tohka, Jussi, 2021, Communications biology, 4, 1, 179. A1 Journal article (refereed), original research - 
                                            
                                                
Microstructural Tissue Changes in a Rat Model of Mild Traumatic Brain Injury
Chary Karthik, Narvaez Omar, Salo Raimo A, San Martín Molina Isabel, Tohka Jussi, Aggarwal Manisha, Gröhn Olli, Sierra Alejandra, 2021, Frontiers in neuroscience, 15, 746214. A1 Journal article (refereed), original research - 
                                            
                                                
Assessment of the structural complexity of diffusion MRI voxels using 3D electron microscopy in the rat brain
Salo, Raimo A; Belevich, Ilya; Jokitalo, Eija; Gröhn, Olli; Sierra, Alejandra, 2020, Neuroimage, 225, 117529. A1 Journal article (refereed), original research - 
                                            
                                                
In vivo diffusion tensor imaging in acute and subacute phases of mild traumatic brain injury in rats
San Martín Molina, Isabel; Salo, Raimo A; Abdollahzadeh, Ali; Tohka, Jussi; Gröhn, Olli; Sierra, Alejandra, 2020, eNeuro, 7, 3, ENEURO.0476-19.2020. A1 Journal article (refereed), original research - 
                                            
                                                
Automated 3D Axonal Morphometry of White Matter
Abdollahzadeh, A; Belevich, I; Jokitalo, E; Tohka, J; Sierra, A, 2019, Scientific reports, 9, 1, 6084. A1 Journal article (refereed), original research - 
                                            
                                                
Quantification of anisotropy and orientation in 3D electron microscopy and diffusion tensor imaging in injured rat brain
Salo, Raimo A; Belevich, Ilya; Manninen, Eppu; Jokitalo, Eija; Gröhn, Olli; Sierra, Alejandra, 2018, Neuroimage, 172, 404-414. A1 Journal article (refereed), original research - 
                                            
                                                
Diffusion tensor MRI shows progressive changes in the hippocampus and dentate gyrus after status epilepticus in rat - histological validation with Fourier-based analysis
Salo RA, Miettinen T, Laitinen T, Gröhn O, Sierra A, 2017, Neuroimage, 152, 221-236. A1 Journal article (refereed), original research