Nina Hakulinen
University Lecturer
Department of Chemistry and Sustainable Technology, Faculty of Science, Forestry and Technology
[email protected] | +358 50 442 2318
PhD 2003, Post-doctoral Researcher 2003-2011, Adjunct Professor (Docent) “Structure-function studies of proteins” 2011, Academy of Finland Research Fellow 2012-2017, University Researcher 2017-
Research interests:
– Structural biology of industrial enzymes
– Enzymatic hydrolysis of lignocellulosic biomass
– Structure and function of metalloenzymes
Research groups
Publications
56/56 items-
Exploring Unspecific Peroxygenase Selectivity with Diverse Hydrocarbon Substrates
Rytkönen, Essi; Hakulinen, Nina; Jänis, Janne; Rouvinen, Juha, 2025, ChemistryOpen, [First published: 09 June 2025], 1-13. A1 Journal article (refereed), original research -
The engineered dimer of L-arabinonate dehydratase from Rhizobium leguminosarum bv. trifolii: The role of intersubunit interactions in IlvD/EDD family
Ren, Yaxin; Vettenranta, Elias; Penttinen, Leena; Jänis, Janne; Rouvinen, Juha; Hakulinen, Nina, 2025, Biochemical and biophysical research communications, 757, 151610. A1 Journal article (refereed), original research -
Achieving thermostability of a phytase with resistance up to 100 °C
Tu, Tao; Wang, Qian; Dong, Ruyue; Liu, Xiaoqing; Penttinen, Leena; Hakulinen, Nina; Tian, Jian; Zhang, Wei; Wang, Yaru; Luo, Huiying; Yao, Bin; Huang, Huoqing, 2024, Journal of biological chemistry, 300, 12, 107992. A1 Journal article (refereed), original research -
Robust Approach for Quantifying Glucocorticoid Binding to the Anti-Cortisol Fab Fragment via Native Mass Spectrometry
Eronen, Veikko; Iljin, Kristiina; Paakkonen, Johan; Janis, Janne; Rouvinen, Juha; Nevanen, Tarja K; Hakulinen, Nina, 2024, ACS omega, 9, 15, 17089-17096. A1 Journal article (refereed), original research -
Structural insights into ternary immunocomplex formation and cross‐reactivity: binding of an anti‐immunocomplex FabB12 to Fab220‐testosterone complex
Eronen, Veikko; Takkinen, Kristiina; Torni, Annika; Peng, Kaichen; Jänis, Janne; Parkkinen, Tarja; Hakulinen, Nina; Rouvinen, Juha, 2024, Febs journal, 291, 21, 4744-4756. A1 Journal article (refereed), original research -
Targeting deoxynivalenol for degradation by a chimeric manganese peroxidase/glutathione system
Su, Xiaoyun; Wang, Shuai; Wang, Xiaolu; Ji, Wangli; Zhang, Honglian; Tu, Tao; Hakulinen, Nina; Luo, Huiying; Bin Yao; Zhang, Wei; Huang, Huoqing, 2024, Ecotoxicology and environmental safety, 273, 116130. A1 Journal article (refereed), original research -
Unveiling the importance of the C-terminus in the sugar acid dehydratase of the IlvD/EDD superfamily
Ren, Yaxin; Vettenranta, Elias; Penttinen, Leena; Blomster Andberg, Martina; Koivula, Anu; Rouvinen, Juha; Hakulinen, Nina, 2024, Applied microbiology and biotechnology, 108, 1, 436. A1 Journal article (refereed), original research -
Effectiveness of ruminal xylanase with an extra proline-rich C-terminus on lignocellulosic biomass degradation
Dong, Ruyue; Liao, Min; Liu, Xiaoqing; Penttinen, Leena; Hakulinen, Nina; Qin, Xing; Wang, Xiaolu; Huang, Huoqing; Luo, Huiying; Yao, Bin; Bai, Yingguo; Tu, Tao, 2023, Bioresource technology, 372, 128695. A1 Journal article (refereed), original research -
Structural insight to elucidate the binding specificity of the anti-cortisol Fab fragment with glucocorticoids
Eronen, Veikko; Tullila, Antti; Iljin, Kristiina; Rouvinen, Juha; Nevanen, Tarja K; Hakulinen, Nina, 2023, Journal of structural biology, 215, 2, 107966. A1 Journal article (refereed), original research -
Boosting enzymatic degradation of cellulose using a fungal expansin: Structural insight into the pretreatment mechanism
Ding, Sunjia; Liu, Xiaoqing; Hakulinen, Nina; Taherzadeh, Mohammad J.; Wang, Yaru; Wang, Yuan; Qin, Xing; Wang, Xiaolu; Yao, Bin; Luo, Huiying; Tu, Tao, 2022, Bioresource technology, 358, 127434. A1 Journal article (refereed), original research