HANI EL-NEZAMY

Contact info

RESEARCH GROUPS - UEF

• 
  Food Research

Publications

• Lo, Emily Kwun Kwan; Lee, Jetty Chung-Yung; Turner, Paul C; El-Nezami, Hani. 2021. Low dose of zearalenone elevated colon cancer cell growth through G protein-coupled estrogenic receptor Scientific reports 11: 7403. 2021
• Wan, Murphy Lam Yim; Co, Vanessa Anna; El-Nezami, Hani. 2021. Endocrine disrupting chemicals and breast cancer: a systematic review of epidemiological studies Critical reviews in food science and nutrition [Epub ahead of print 5 April 2021]: 1 28. 2021
• Xu, Jinghang; Zhan, Qiao; Fan, Yanan; Lo, Emily Kwun Kwan; Zhang, Fangfei; Yu, Yanyan; El-Nezami, Hani; Zeng, Zheng. 2021. Clinical Aspects of Gut Microbiota in Hepatocellular Carcinoma Management Pathogens 10 7: 782. 2021
• Zhan, Qiao; Xu, Jing-Hang; Yu, Yan-Yan; Lo, Emily K N; Felicianna; El-Nezami, Hani; Zeng, Zheng. 2021. Human immune repertoire in hepatitis B virus infection World journal of gastroenterology 27 25: 3790-3801. 2021
• Kårlund, Anna; Gómez-Gallego, Carlos; Korhonen, Jenni; Palo-Oja, Outi-Maaria; El-Nezami, Hani; Kolehmainen, Marjukka. 2020. Harnessing Microbes for Sustainable Development: Food Fermentation as a Tool for Improving the Nutritional Quality of Alternative Protein Sources Nutrients 12 4: 1020. 2020
• So, Stephanie Sik Yu; Yeung, Chris Ho Ching; Schooling, C Mary; El-Nezami, Hani. 2020. Reply to Alizadeh's letter to the editor on "Targeting bile acid metabolism in obesity reduction: A systematic review and meta-analysis" Obesity reviews 21 10: e13075. 2020
• So, Stephanie Sik Yu; Yeung, Chris Ho Ching; Schooling, C Mary; El-Nezami, Hani. 2020. Targeting Bile Acid Metabolism in Obesity Reduction: A Systematic Review and Meta-Analysis Obesity reviews 21 7: e13017. 2020
• Wan, Murphy L Y; Co, Vanessa Anna; El-Nezami, Hani. 2020. Dietary polyphenol impact on gut health and microbiota Critical reviews in food science and nutrition 2021; 61 4: 690-711. 2020
• Wu, Qinglong; Chen, Tingtao; El-Nezami, Hani; Savidge, Tor. 2020. Food ingredients in human health: Ecological and metabolic perspectives implicating gut microbiota function Trends in food science and technology 100: 103-117. 2020
• Kårlund, A; Gómez-Gallego, C; Turpeinen, AM; Palo-Oja, OM; El-Nezami, H; Kolehmainen, M. 2019. Protein Supplements and Their Relation with Nutrition, Microbiota Composition and Health: Is More Protein Always Better for Sportspeople? Nutrients 11 4: 829. 2019
• Ndika, J; Seemab, U; Poon, WL; Fortino, V; El-Nezami, H; Karisola, P; Alenius, H. 2019. Silver, titanium dioxide, and zinc oxide nanoparticles trigger miRNA/isomiR expression changes in THP-1 cells that are proportional to their health hazard potential Nanotoxicology 13 10: 1380-1395. 2019
• Poon, WL; Lee, JC; Leung, KS; Alenius, H; El-Nezami, H; Karisola, P. 2019. Nanosized silver, but not titanium dioxide or zinc oxide, enhances oxidative stress and inflammatory response by inducing 5-HETE activation in THP-1 cells Nanotoxicology 2020; 14 4: 453-467. 2019
• Sahlman, H; Koponen, M; El-Nezami, H; Vahakangas, K; Keski-Nisula, L. 2019. Maternal use of drugs and preeclampsia British journal of clinical pharmacology 85 12: 2848-2855. 2019
• Wan, MLY; Turner, PC; Co, VA; Wang, MF; Amiri, KMA; El-Nezami, H. 2019. Schisandrin A protects intestinal epithelial cells from deoxynivalenol-induced cytotoxicity, oxidative damage and inflammation Scientific reports 9: 19173. 2019
• Wan, Murphy Lam-Yim; Chen, Zhijian; Shah, Nagendra P; El-Nezami, Hani. 2018. Effects of Lactobacillus rhamnosus GG and Escherichia coli Nissle 1917 Cell-Free Supernatants on Modulation of Mucin and Cytokine Secretion on Human Intestinal Epithelial HT29-MTX Cells Journal of Food Science 83 7: 1999-2007. 2018
• Wan, Muprhy LY; Ling, KH; El-Nezami, Hani; Wang, MF. 2018. Influence of functional food components on gut health Critical reviews in food science and nutrition 2019; 59 12: 1927-1936. 2018
• Wan, Murphy Lam Yim; Forsythe, Stephen J; El-Nezami, Hani. 2018. Probiotics interaction with foodborne pathogens: a potential alternative to antibiotics and future challenges Critical reviews in food science and nutrition 2019; 59 20: 3320-3333. 2018
• Wan, MLY; El-Nezami, H. 2018. Targeting gut microbiota in hepatocellular carcinoma: probiotics as a novel therapy. Hepatobiliary surgery and nutrition 7 1: 11-20. 2018
• Ni Y, Wong VHY, Tai WCS, Li J, Wong WY, Lee MML, Fong FLY, El-Nezami H, Panagiotou G. 2017. A metagenomic study of the preventive effect of Lactobacillus rhamnosus GG on intestinal polyp formation in ApcMin/+ mice. JOURNAL OF APPLIED MICROBIOLOGY 122 3: 770-784. 2017
• Poon Wing-Lam, Alenius Harri, Ndika Joseph, Fortino Vittorio, Kolhinen Vesa, Mesceriakovas Arunas, Wang Mingfu, Greco Dario, Lähde Anna, Jokiniemi Jorma, Lee Jetty Chung-Yung, El-Nezami Hani, Karisola Piia. 2017. Nano-sized zinc oxide and silver, but not titanium dioxide, induce innate and adaptive immunity and antiviral response in differentiated THP-1 cells. Nanotoxicology 11 7: 936-951. 2017
• Yip Ka Yiu, Wan Murphy Lam Yim, Wong Alice Sze Tsai, Korach Kenneth S, El-Nezami Hani. 2017. Combined Low-Dose Zearalenone and Aflatoxin B1 on Cell Growth and Cell-Cycle Progression in Breast Cancer MCF-7 Cells. TOXICOLOGY LETTERS 281: 139-151. 2017
• Chan Yee Kwan, El-Nezami Hani, Chen Yan, Kinnunen Kristiina, Kirjavainen Pirkka V. 2016. Probiotic mixture VSL#3 reduce high fat diet induced vascular inflammation and atherosclerosis in ApoE-/- mice. AMB Express 6: 61-68. 2016
• Chan YK, Brar MS, Kirjavainen PV, Chen Y, Peng J, Li D, Leung FC-C, El-Nezami H. 2016. High fat diet induced atherosclerosis is accompanied with low colonic bacterial diversity and altered abundances that correlates with plaque size, plasma A-FABP and cholesterol: a pilot study of high fat diet and its intervention with Lactobacillus rhamnosus GG (LGG) or telmisartan in ApoE-/- mice. BMC Microbiology 16: 264. 2016
• Fong FL, Kirjavainen PV, El-Nezami H. 2016. Immunomodulation of Lactobacillus rhamnosus GG (LGG)-derived soluble factors on antigen-presenting cells of healthy blood donors. Scientific Reports 6: 22845. 2016
• Li J, Sung CY, Lee N, Ni Y, Pihlajamäki J, Panagiotou G, El-Nezami H. 2016. Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 113 9: E1306-E1315. 2016
• Ling Ka-Ho, Lam Yim Wan Murphy, El-Nezami Hani, Wang Mingfu. 2016. Protective Capacity of Resveratrol, a Natural Polyphenolic Compound, against Deoxynivalenol-Induced Intestinal Barrier Dysfunction and Bacterial Translocation. CHEMICAL RESEARCH IN TOXICOLOGY 29 5: 823-833. 2016
• So Stephanie S, Wan Murphy L El-Nezami Hani. 2016. Probiotics-mediated suppression of cancer. Current opinion in oncology 2017; 29 1: 62-72. 2016
• Wan LYM, Chen ZJ, Shah NP, El-Nezami H. 2016. Modulation of Intestinal Epithelial Defense Responses by Probiotic Bacteria. Critical reviews in food science and nutrition 56 16: 2628-2641. 2016
• Wan MLY, Ling KH, Wang MF, El-Nezami H. 2016. Green tea polyphenol epigallocatechin-3-gallate improves epithelial barrier function by inducing the production of antimicrobial peptide pBD-1 and pBD-2 in monolayers of porcine intestinal epithelial IPEC-J2 cells. Molecular Nutrition & Food Research 60 5: 1048-1058. 2016
• Wan Murphy LY, Turner Paul C, Allen Kevin J, El-Nezamia Hani. 2016. Lactobacillus rhamnosus GG modulates intestinal mucosal barrier and inflammation in mice following combined dietary exposure to deoxynivalenol and zearalenone. Journal of Functional Foods 22: 34-43. 2016
• Fong Fiona Long Yan, Kirjavainen Pirkka, Wong Victoria Ho Yee, El-Nezami Hani. 2015. Immunomodulatory effects of Lactobacillus rhamnosus GG on dendritic cells, macrophages and monocytes from healthy donors. Journal of Functional Foods 13: 71-79. 2015
• Wan L-YM, Allen KJ, Turner PC, El-Nezami H. 2014. Modulation of Mucin mRNA (MUC5AC and MUC5B) Expression and Protein Production and Secretion in Caco-2/HT29-MTX Co-cultures Following Exposure to Individual and Combined Fusarium Mycotoxins. TOXICOLOGICAL SCIENCES Epub ahead of print: -. 2014
• Wan L-YM, Woo C-SJ, Turner PC, Wan JM-F, El-Nezami H. 2013. Individual and combined effects of Fusarium toxins on the mRNA expression of pro-inflammatory cytokines in swine jejunal epithelial cells. TOXICOLOGY LETTERS 220: 238-246. 2013
• Wan LYM, Turner PC, El-Nezami H. 2013. Individual and combined cytotoxic effects of Fusarium toxins (deoxynivalenol, nivalenol, zearalenone and fumonisins B1) on swine jejunal epithelial cells. FOOD AND CHEMICAL TOXICOLOGY 57: 276-283. 2013
• Wan, ML-Y, Woo C-SJ, Allen KJ, Turner PC, El-Nezami H. 2013. Modulation of Porcine β-Defensins 1 and 2 upon Individual and Combined Fusarium Toxin Exposure in a Swine Jejunal Epithelial Cell Line. APPLIED AND ENVIRONMENTAL MICROBIOLOGY 79 7: 2225-2232. 2013
• Piekkola S, Turner PC, Abdel-Hamid M, Ezzat S, El-Daly M, El-Kafrawy S, Savchenko E, Poussa T, Woo JCS, Mykkänen H, El-Nezami H. 2012. Characterisation of aflatoxin and deoxynivalenol exposure among pregnant Egyptian women Food Additives and Contaminants. Part A 29 6: 962-971. 2012
• Wang QL, Wu Q, Tao YY, Liu CH, El-Nezami H. 2011. Salvianolic acid B modulates the expression of drug-metabolizing enzymes in HepG2 cells Hepatobiliary & Pancreatic Diseases International 10: 502-508. 2011
• Wilson Gratz S, Mykkanen H, El-Nezami HS.. 2010. Probiotics and gut health: a special focus on liver diseases. WORLD JOURNAL OF GASTROENTEROLOGY 16 4: 403-410. 2010
• Halttunen T, Collado MC, El-Nezami H, Mesiluoto J, Salminen S, El-Nezami H. 2008. Combining strains of lactic acid bacteria may reduce their toxin and heavy metal removal efficiency from aqueous solution. LETTERS IN APPLIED MICROBIOLOGY 46 2: 160-165. 2008
• Hatakka K, Holma R, El-Nezami H, Suomalainen T, Kuisma M, Saxelin M, Poussa T, Mykkänen H, Korpela R. 2008. The influence of Lactobacillus rhamnosus LC705 together with Propionibacterium freudenreichii ssp. shermanii JS on potentially carcinogenic bacterial activity in human colon. INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY 128: 406-410. 2008
• Polychronaki N, Wild CP, Mykkänen H, Amra H, Abdel-Wahhab M, Sylla A, Diallo M, El-Nezami H, Turner PC, Polychronaki N, El-Nezami H. 2008. Urinary biomarkers of aflatoxin exposure in young children from Egypt and Guinea FOOD AND CHEMICAL TOXICOLOGY 46: 519-526. 2008
• Turner PC, Wu QK, Piekkola S, Gratz S, Mykkänen H, El-Nezami H, Piekkola S, Mykkänen H, El-Nezami H. 2008. Lactobacillus rhamnosus strain GG resores alkaline phosphatase activity in differentiating Caco-2 cells dosed with the potent mycotoxin deoxynivalenol. FOOD AND CHEMICAL TOXICOLOGY 46: 2118-2123. 2008
• Gratz S, Wu QK, El-Nezami H, Juvonen RO, Mykkänen H, Turner PC, Gratz S, WU QK, El-Nezami H. 2007. Lactobacillus rhamnosus strain GG reduces aflatoxin B1 transport, metabolism, and toxicity in Caco-2 cells APPLIED AND ENVIRONMENTAL MICROBIOLOGY 73 12: 3958-3964. 2007
• Gråsten SM, Juntunen KS, Mättö J, Mykkänen OT, El-Nezami H, Adlercreutz H, Poutanen KS, Mykkänen HM, Mykkänen OT, El-Nezami H, Poutanen KS. 2007. High-fiber rye bread improves bowel function in postmenopausal women but does not cause other putatively positive changes in the metabolic activity of intestinal microbiota. NUTRITION RESEARCH 27: 454-461. 2007
• Polychronaki N, West RM, Turner PC, Amra H, Abdel-Wahhab M, Mykkänen H, El-Nezami H, Polychronaki N, El-Nezami H. 2007. A longitudinal assessment of aflatoxin M1 excretion in breast milk of selected Egyptian mothers FOOD AND CHEMICAL TOXICOLOGY 45: 1210-1215. 2007
• Polychronaki N, Turner PC, Mykkänen H, Gong Y, Amra H, Abdel-Wahhab M, El-Nezami H, Polychronaki N, El-Nezami H. 2006. Determinants of aflatoxin M1 in breast milk in a selected group of Egyptian mothers. FOOD ADDITIVES AND CONTAMINANTS 23: 700-708. 2006
• Ibrahim F, Salminen S, Mykkänen H, El-Nezami H, Salminen E, Ma J, Ling WH, Benno Y, Tahvonen R. 2006. Cadmium and lead elimination in young male chinese students. A probiotic intervention study. NUTRAFOODS 5: 5-9. 2006
• Gratz S, Täubel M, Juvonen RO, Viluksela M, Turner PC, Mykkänen H, El-Nezami H, Gratz S, Täubel M, El-Nezami H. 2006. Lactobacillus rhamnosus strain GG modulates intestinal absorption, fecal excretion, and toxicity of aflatoxin B1 in rats. APPLIED AND ENVIRONMENTAL MICROBIOLOGY 72 11: 7398-7400. 2006
• El-Nezami HS, Polychronaki NN, Ma J, Zhu H, Ling W, Salminen EK, Juvonen RO, Salminen SJ, Poussa T, Mykkänen HM, El-Nezami HS, Polychronaki NN, Mykkänen HM. 2006. Probiotic supplementation reduces a biomarker for increased risk of liver cancer in young men from Southern China. AMERICAN JOURNAL OF CLINICAL NUTRITION 83: 1199-1203. 2006
• Gratz S, Mykkänen H, El-Nezami H, Gratz S, El-Nezami H. 2005. Aflatoxin B1 binding by a mixture of lactobacillus and propionibacterium: in vitro versus ex vivo. JOURNAL OF FOOD PROTECTION 68: 2470-2474. 2005
• Mykkänen H, Zhu H, Salminen E, Juvonen RO, Ling W, Ma J, Polychronaki N, Kemiläinen H, Mykkänen O, Salminen S, El-Nezami H, Mykkänen H, Polychronaki, Kemiläinen H, Mykkänen O, El-Nezami H. 2005. Fecal and urinary excretion of aflatoxin B1 metabolites (AFQ1, AFM1 and AFB-N7-guanine) in young Chinese males. INTERNATIONAL JOURNAL OF CANCER 115: 879-884. 2005
• Salminen S, El-Nezami H, Salminen E, Mykkänen H. 2005. Probiotics: Synenergy with drugs and carcinogens in diet: Thompson LU, Ward WE, Food-Drug Synergy and Safety.Taylor & Francis. 219-232. 2005
• El-Nezami H, Polychronaki N, Lee YK, Haskard C, Juvonen R, Salminen S, Mykkänen H, El-Nezami H. 2004. Chemical moieties and interactions involved in the binding of zearalenone to the surface of lactobacillus rhamnosus strains GG. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 52: 4577-4581. 2004
• El-Nezami HS, Salminen S, Salminen E, Mykkänen H. 2004. Lactic acid bacteria as a tool for enhancing food safety by removal of dietary toxins. In: Salminen S; von Wright A; Ouwehand A (ed.) , Lactic acid bacteria:Microbiology and functional aspects.Marcel Deccer,Inc.. ss. 397-406. 2004
• Gratz S, Mykkänen H, Ouwehand AC, Juvonen R, Salminen S, El-Nezami H, Gratz S, El-Nezami H. 2004. Intestinal mucus alters the ability of probiotic bacteria to bind aflatoxin B1 in vitro. APPLIED AND ENVIRONMENTAL MICROBIOLOGY 70 10: 6306-6308. 2004
• Gråsten S, Liukkonen K-H, Chrevatidis A, El-Nezami H, Poutanen K, Mykkänen H. 2003. Effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function in healthy humans NUTRITION RESEARCH 23: 1503-1514. 2003
• Lee YK, El-Nezami H, Haskard CA, Gratz S, Puong KY, Salminen S, Mykkänen H. 2003. Kinetics of adsorption and desorption of alfatoxin B1 by viable and nonviable bacteria JOURNAL OF FOOD PROTECTION 66 3: 426-430. 2003
• El-Nezami H, Polychronaki N, Salminen S, Mykkänen H. 2002. Binding rather than metabolism may explain the interaction of two food-grade lactobacillus strains with zearalenone and its derivative alfa-zearalenol. APPLIED AND ENVIRONMENTAL MICROBIOLOGY 68: 3545-3549. 2002
• El-Nezami H, Salminen S, Mykkänen H. 2002. Probiotic bacteria-mycotoxins interactopns: an approach to enhance food safety. POLISH JOURNAL OF FOOD AND NUTRITION SCIENCES 11: 39-43. 2002
• El-Nezami HS, Chrevatidis A, Auriola S, Salminen S, Mykkänen H. 2002. Removal of common Fusarium toxins in vitro by strains of Lactobacillus and Propionibacterium. FOOD ADDITIVES AND CONTAMINANTS 19: 680-686. 2002
• El-Nezami H, Mykkänen H, Kankaanpää P, Salminen S, Ahokas J. 2000. Ability of lactobacillus and propionibacterium strains to remove aflatoxin B1 from the chicken duodenum. JOURNAL OF FOOD PROTECTION 63 4: 549-552. 2000
• El-Nezami H, Mykkänen H, Kankaanpää P, Suomalainen T, Salminen S, Ahokas J. 2000. Ability of a mixture of lactobacillus and propionibacterium to influence the faecal aflatoxin content in healthy egyptian volunteers: A pilot clinical study. BIOSCIENCE MICROFLORA 19 1: 41-45. 2000