Ilkka Harvima

Kallionpää, Roope A.; Ahramo, Kaisa; Martikkala, Eija; Fazeli, Elnaz; Haapaniemi, Pekka; Rokka, Anne; Leivo, Ilmo; Harvima, Ilkka T.; Peltonen, Juha; Peltonen, Sirkku. 2021. Mast Cells in Human Cutaneous Neurofibromas: Density, Subtypes, and Association with Clinical Features in Neurofibromatosis 1 Dermatology 2022; 238 2: 329-339. 2021

Komulainen, Jenni; Siiskonen, Hanna; Harvima, Ilkka T. 2021. Association of Elevated Serum Tryptase with Cutaneous Photodamage and Skin Cancers International archives of allergy and immunology 182 11: 1135-1142. 2021

Suhonen, Ville; Rummukainen, Jaana; Siiskonen, Hanna; Mannermaa, Arto; Harvima, Ilkka T. 2021. High regional mortality due to malignant melanoma in Eastern Finland may be explained by the increase in aggressive melanoma types Bmc cancer 21: 1155. 2021

Kosketusallergeenit. Harvima, Ilkka / Allergiset sairaudet ja astma. 2020. 2020

Urtikariaa muistuttavia ihoraktioita aiheuttavat taudit. Harvima, Ilkka; Ackermann, Leena / Allergiset sairaudet ja astma. 2020. 2020

Urtikaria ja sen ilmeneminen. Harvima, Ilkka; Ackermann, Leena / Allergiset sairaudet ja astma. 2020. 2020

Akuutti urtikaria. Harvima, Ilkka; Ackermann, Leena / Allergiset sairaudet ja astma. 2020. 2020

Krooninen spontaani urtikaria. Harvima, Ilkka; Ackermann, Leena / Allergiset sairaudet ja astma. 2020. 2020

Krooninen indusoituva urtikaria. Harvima, Ilkka; Ackermann, Leena / Allergiset sairaudet ja astma. 2020. 2020

Kroonisen urtikarian hoito. Harvima, Ilkka; Ackermann, Leena / Allergiset sairaudet ja astma. 2020. 2020

Kontaktiallergia. Harvima, Ilkka / Allergiset sairaudet ja astma. 2020. 2020

Ihotestit allergiadiagnostiikassa. Harvima, Ilkka / Allergiset sairaudet ja astma. 2020. 2020

Harvima, RJ; Halonen, P; Pirinen, E; Kolehmainen-Harvima, KS; Harvima, IT. 2020. Successful treatment of iatrogenically developed cutaneous calcification by tetracycline in Labrador retriever Animal Husbandry, Dairy and Veterinary Science 4 3: 1-4. 2020

Angioödeemat. Harvima, Ilkka; Ackermann, Leena / Allergiset sairaudet ja astma. 2020. 2020

Allergiset sairaudet ja astma. Mäkelä, Mika; Harvima, Ilkka; Kauppi, Paula; Ralli, Pia; Savolainen, Johannes. 2020 2020

Allergiseen reaktioon osallistuvat solut. Virtanen, Tuomas; Savolainen, Johannes; Harvima, Ilkka / Allergiset sairaudet ja astma. 2020. 2020

Lipitsä, T; Siiskonen, H; Naukkarinen, A; Harvima, IT. 2019. Mast cell chymase degrades fibrinogen and fibrin British journal of dermatology 181 2: 296-303. 2019

Rahkola, Dina; Laitala, Joel; Siiskonen, Hanna; Pelkonen, Jukka; Harvima, Ilkka T. 2019. Mast Cells Are a Marked Source for Complement C3 Products That Associate with Increased CD11b-Positive Cells in Keratinocyte Skin Carcinomas Cancer investigation 37 2: 73-84. 2019

Siiskonen, Hanna; Harvima, Ilkka. 2019. Mast Cells and Sensory Nerves Contribute to Neurogenic Inflammation and Pruritus in Chronic Skin Inflammation Frontiers in cellular neuroscience 13: 422. 2019

Gupta, Kalpna; Harvima, Ilkka T. 2018. Mast cell-neural interactions contribute to pain and itch. Immunological Reviews 282 1: 168-187. 2018

Suttle, Mireille-Maria; Ritanen, Riikka-Liisa; Harvima, Ilkka T. 2018. Increase in FoxP3-positive Cells and Their Contacts with Mast Cells in Köbner-negative Patients with Psoriasis after Tape-stripping ACTA DERMATO-VENEREOLOGICA 2019; 99 1: 103-104. 2018

Virén, T; Iivarinen, JT; Sarin, JK; Harvima, I; Mayrovitz, HN. 2018. Accuracy and reliability of a hand-held in vivo skin indentation device to assess skin elasticity. International Journal of Cosmetic Science 40 2: 134-140. 2018

Haimakainen S, Kaukinen AP, Suttle M-M, Pelkonen J, Harvima IT. 2017. CD40 Ligand Is Increased in Mast Cells in Psoriasis and Actinic Keratosis but Less So in Epithelial Skin Carcinomas. Cancer Investigation 35 3: 143-151. 2017

Kaukinen Antti, Siiskonen Harri, Pelkonen Jukka, Harvima Ilkka T. 2017. Immunoreactivity to CYP24A1, but not vitamin D receptor, is increased in mast cells of keratinocyte skin cancers. EUROPEAN JOURNAL OF DERMATOLOGY 27 6: 590-598. 2017

Siiskonen Hanna, Harvima Ilkka. 2017. Melanooman riskitekijät. SUOMEN LÄÄKÄRILEHTI 72 24: 1563-1569. 2017

Lipitsä T, Naukkarinen A, Laitala J, Harvima IT. 2016. Complement C3 is expressed by mast cells in cutaneous vasculitis and is degraded by chymase. ARCHIVES OF DERMATOLOGICAL RESEARCH [first online 27 July 2017]: 1-10. 2016

Harvima Ilkka, Kähäri Veli-Matti, Ranki Annamari, Snellman Erna, Tasanen-Määttä Kaisa. 2016. Kansallinen ihosyöpäohjelma tarvitaan nyt. SUOMEN LÄÄKÄRILEHTI 71 7: 462-463. 2016

Ilves T, Virolainen A, Harvima IT. 2016. Immediate Wheal Reactivity to Autologous Sweat in Atopic Dermatitis Is Associated with Clinical Severity, Serum Total and Specific IgE and Sweat Tryptase Activity. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 170 2: 84-91. 2016

Elomaa Antti-Pekka, Viinamäki Heimo, Harvima Ilkka T, Koivumaa-Honkanen, Honkalampi Kirsi, Valkonen-Korhonen Minna, Lehti Soili M. 2016. Increased mitogen-stimulated lymphocyte proliferation is associated with the clinical response in major depressive disorder in women: A follow-up study. PSYCHIATRY RESEARCH 239: 220-221. 2016

Ilves Tiina, Tiitu Virpi, Suttle Mireille-Maria, Saarinen Jari Vilho, Harvima Ilkka Tapani. 2015. Epidermal Expression of Filaggrin/Profilaggrin Is Decreased in Atopic Dermatitis: Reverse Association With Mast Cell Tryptase and IL-6 but Not With Clinical Severity. Dermatitis 26 6: 260-267. 2015

Kaukinen Antti, Pelkoonen Jukka, Harvima Ilkka T. 2015. Mast cells express CYP27A1 and CYP27B1 in epithelial skin cancers and psoriasis. EUROPEAN JOURNAL OF DERMATOLOGY [epub ahead of print]: -. 2015

Lipitsä Tiina, Naukkarinen Anita, Harvima Ilkka T. 2015. Mast cell tryptase and chymase in the progress of cutaneous vasculitis. ARCHIVES OF DERMATOLOGICAL RESEARCH 307 10: 917-924. 2015

Siiskonen Hanna, Poukka Mari, Bykachev Andrey, Tyynelä-Korhonen Kristiina, Sironen Reijo, Pasonen-Seppänen Sanna, Harvima Ilkka T. 2015. Low numbers of tryptase+ and chymase+ mast cells associated with reduced survival and advanced tumor stage in melanoma. MELANOMA RESEARCH [epub ahead of print 27 July 2015]: -. 2015

Suttle Mireille-Maria, Harvima Ilkka T. 2015. Mast cell chymase in experimentally induced psoriasis. JOURNAL OF DERMATOLOGY 2016; 43 6: 693-696. 2015

Harvima Ilkka T, Levi-Schaffer Francesca, Draber Petr, Friedman Sheli, Polakovicova Iva, Gibbs Bernhard F, Blank Ulrich, Nilsson Gunnar, Maurer Marcus. 2014. Molecular targets on mast cells and basophils for novel therapies. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 134 3: 530-544. 2014

Honkalampi K, Viinamäki H, Niskanen L, Koivumaa-Honkanen H, Valkonen-Korhonen M, Elomaa AP, Harvima I, Herzig KH, Lehto SM. 2014. Reduced serum adiponectin levels in alexithymia. NeuroImmunoModulation 21 5: 234-239. 2014

Ilves T, Harvima I. 2014. Decrease in Chymase Activity is Associated with Increase in IL-6 Expression in Mast Cells in Atopic Dermatitis. ACTA DERMATO-VENEREOLOGICA Epub: --. 2014

Kaukinen A, Fitzgibbon A, Oikarinen A, Hinkkanen L, Viinikanoja M, Harvima IT. 2014. Increased Numbers of Tryptase-Positive Mast Cells in the Healthy and Sun-Protected Skin of Tobacco Smokers. DERMATOLOGY 229 4: 353-358. 2014

Suttle MM, Enoksson M, Zoltowska A, Chatterjee M, Nilsson G, Harvima IT. 2014. Experimentally Induced Psoriatic Lesions Associate with Rapid but Transient Decrease in Interleukin-33 Immunostaining in Epidermis Acta dermato-venereologica 95 5: 536-541. 2014

Viinamäki, Heimo; Lehto, Soili M.; Palvimo, Jorma J., Harvima, Ilkka; Valkonen-Korhonen, Minna; Koivumaa-Honkanen, Heli; Hintikka, Jukka; Honkalampi, Kirsi ja Niskanen Leo. 2012. Glukokortikoidien yhteys masennuksen syntyyn ja oirekuvaan DUODECIM 128 10: 1022-1029. 2012

Suttle, M.-M; Nilsson, G; Snellman, E; Harvima IT. 2012. Experimentally induced psoriatic lesion associates with interleukin (IL)-6 in mast cells and appearance of dermal cells expressing IL-33 and IL-6 receptor CLINICAL AND EXPERIMENTAL IMMUNOLOGY 169: 311-319. 2012

Harvima I, Nilsson G. 2012. Stress, the neuroendocrine system and mast cells: current understanding of their role in psoriasis. Expert Review of Clinical Immunology 8 3: 235-241. 2012

Ilves T, Harvima I. 2012. OX40 ligand and OX40 are increased in atopic dermatitis lesions but do not correlate with clinical severity. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY : JEADV 2012: 1-9. 2012

Ekoff M, Lyberg K, Krajewska M, Arvidsson M, Rak S, Reed JC, Harvima I, Nilsson G. 2012. Anti-apoptotic bfl-1 is the major effector in activation-induced human mast cell survival. PLOS ONE [ONLINE] 7 6: e39117; 1-7. 2012

Elomaa A-P, Niskanen L, Herzig K-H, Viinamäki H, Hintikka J, Koivumaa-Honkanen H, Honkalampi K, Valkonen-Korhonen M, Harvima I, Lehto SM. 2012. Elevated levels of serum IL-5 are associated with an increased likelihood of major depressive disorder BMC PSYCHIATRY [HTTP://WWW.BIOMEDCENTRAL.COM/1471-244X/] 12: 2. 2012

Diaconu Nicolae-Costin, Rummukainen Jaana, Naukkarinen Anita, Mättö Mikko, Harvima Rauno J, Pelkonen Jukka, Harvima Ilkka T.. 2011. Mast cell chymase is present in uterine cervical carcinoma and it detaches viable and growing cervical squamous carcinoma cells from substratum in vitro. ARCHIVES OF DERMATOLOGICAL RESEARCH 303 7: 499-512. 2011

Harvima IT, Nilsson G. 2011. Mast cells as regulators of skin inflammation and immunity ACTA DERMATO-VENEREOLOGICA 91 6: 644-650. 2011

da Silva Carvalho RF, Nilsson G & Harvima IT. 2010. Increased mast cell expression of PAR-2 in skin inflammatory diseases and release of IL-8 upon PAR-2 activation EXPERIMENTAL DERMATOLOGY 19: 117-122. 2010

I.T. Harvima, G. Nilsson, A. Naukkarinen. 2010. Role of mast cells and sensory nerves in skin inflammation. GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA 145: 195-204. 2010

Mats Karlberg, Maria Ekoff, David C.S. Huang, Paula Mustonen, Ilkka T. Harvima & Gunnar Nilsson. 2010. The BH3-Mimetic ABT-737 Induces Mast Cell Apoptosis In Vitro and In Vivo: Potential for Therapeutics JOURNAL OF IMMUNOLOGY (BALTIMORE) 185: 2555-2562. 2010

Sime W, Lunderius-Andersson C, Enoksson M, Rousselle P, Tryggvason K, Nilsson G, Harvima I, Patarroyo M. 2009. Human mast cells adhere to and migrate on epithelial and vascular basement membrane laminins LM-332 and LM-511 via alpha(3)beta(1) integrin. JOURNAL OF IMMUNOLOGY (BALTIMORE) 183 7: 4657-4665. 2009

Diaconu N-C, Rummukainen J, Mättö M, Naukkarinen A, Harvima RJ, Pelkonen J, Harvima IT. 2008. Cervical squamous carcinoma cells are resistant to the combined action of tumor necrosis factor-alpha and histamine whereas normal keratinocytes undergo cytolysis BMC CANCER [ONLINE: HTTP://WWW.BIOMEDCENTRAL.COM/BMCCANCER/] 8: [15, art. 46]. 2008

Harvima IT, Nilsson G, Suttle MM, Naukkarinen A. 2008. Is there a role for mast cells in psoriasis?. ARCHIVES OF DERMATOLOGICAL RESEARCH 300 9: 461-78. 2008

Harvima IT. 2008. Induction of matrix metalloproteinase-9 in keratinocytes by histamine. JOURNAL OF INVESTIGATIVE DERMATOLOGY 128 12: 2748-50. 2008

Kälviäinen R, Eriksson K, Losekoot M, Sorri I, Harvima I, Santavuori P, Järvelä I, Autti T, Vanninen R, Salmenperä T, van Diggelen OP. 2007. Juvenile-onset neuronal ceroid lipofuscinosis with infantile CNL1 mutation and palmitoyl-protein thioesterase deficiency. EUROPEAN JOURNAL OF NEUROLOGY 14: 369-372. 2007

Nuutinen P, Harvima IT, Ackermann L. 2007. Histamine, but not leukotriene C4, is an essential mediator in cold urticaria wheals ACTA DERMATO-VENEREOLOGICA 87 1: 9-13. 2007

Gulliksson M, Brunnström A, Johannesson M, Backman L, Nilsson G, Harvima I, Dahlén B, Kumlin M, Claesson HE. 2007. Expression of 15-lipoxygenase type-1 in human mast cells. BIOCHIMICA ET BIOPHYSICA ACTA 1771 9: 1156-1165. 2007

Diacony NC, Kaminska R, Naukkarinen A, Harvima R, Harvima I. 2007. The increase in tryptase- and chymase-positive mast cells is associated with partial inactivation of chymase and increase in protease inhibitors in basal cell carcinoma. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY : JEADV 21 7: 908-915. 2007

Diaconu NC, Kaminska R, Naukkarinen A, Harvima RJ, Nilsson G, Harvima IT. 2007. Increase in CD30 ligand/CD153 and TNF-alpha expressing mast cells in basal cell carcinoma. CANCER IMMUNOLOGY AND IMMUNOTHERAPY 56 9: 1407-1415. 2007

Fischer M, Harvima IT, Carvalho RFS, Möller C, Naukkarinen A, Enblad G, Nilsson G. 2006. Mast cell CD30 ligand is upregulated in cutaneus inflammation and mediates degranulation-independent chemokine secretion. JOURNAL OF CLINICAL INVESTIGATION 116 10: 2748-2756. 2006

Harvima IT, Heikura H, Hyttinen M, Naukkarinen A. 2006. Hyaluronic acid inhibits the adherence and growth of monolayer keratinocytes but does not affect the growth of keratinocyte epithelium. ARCHIVES OF DERMATOLOGICAL RESEARCH 298 5: 207-219. 2006

Amin K, Janson C, Harvima I, Venge P, Nilsson G. 2005. CC chemokine receptors CCR1 and CCR4 are expressed on airway mast cells in allergic asthma. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 116 6: 1383-386. 2005

Callaway J, Schwab U, Harvima I, Halonen P, Mykkänen O, Hyvönen P, Järvinen T. 2005. Efficacy of dietary hempseed oil in patients with atopic dermatitis. JOURNAL OF DERMATOLOGICAL TREATMENT 16: 87-94. 2005

El-Nour H, Lundeberg L, Boman A, Beck O, Harvima IT, Theodorsson E, Nordlind K. 2005. Study of innervation, sensory neuropeptides, and serotonin in murine contact allergic skin. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 27 1: 67-76. 2005

Huttunen M, Harvima IT. 2005. Mast cell tryptase and chymase in chronic leg ulcers: chymase is potentially destructive to epithelium and is contolled by proteinase inhibitors BRITISH JOURNAL OF DERMATOLOGY 152: 1149-1160. 2005

Mäntylä T, Sirola H, Kansanen E, Korjamo T, Lankinen H, Lappalainen K, Välimaa AL, Harvima I, Närvänen A. 2005. Effect of temporin A modifications on its cytotoxicity and antimicrobial activity APMIS: ACTA PATHOLOGICA ET MICROBIOLOGICA SCANDINAVICA 113: 497-505. 2005

Harvima IT, Lappalainen K, Hirvonen MR, Matto M, Kivinen PK, Hyttinen M, Pelkonen J, Naukkarinen A. 2004. Heparin modulates the growth and adherence and augments the gowth-inhibitory action of TNF-alpha on cultured human keratinocytes. JOURNAL OF CELLULAR BIOCHEMISTRY 92 2: 372-386. 2004

Riekki R, Harvima IT, Jukkola A, Risteli J, Oikarinen A. 2004. The production of collagen and the activity of mast-cell chymase increase in human skin after irridation therapy. EXPERIMENTAL DERMATOLOGY 13 6: 364-71. 2004

Nuutinen J, Harvima I, Lahtinen M-R, Lahtinen T. 2003. Water loss through the lip, nail, eyelid skin, scalp skin, and axillary skin measured with a closed-chamber evaporation principle. BRITISH JOURNAL OF DERMATOLOGY 148 4: 839-841. 2003

Nuutinen J, Alanen E, Autio P, Lahtinen M-R, Harvima I, Lahtinen T. 2003. A closed unventilated chamber for the measurement of transepidermal water loss. SKIN RESEARCH AND TECHNOLOGY 9 2: 85-89. 2003

Kivinen PK, Lahtinen M-R, Ruotsalainen E, Harvima IT, Katila M-L. 2003. Bergeyella zoohelcum septicaemia of a patient suffering from severe skin infection. ACTA DERMATO-VENEREOLOGICA 83 1: 74-75. 2003

Kivinen PK, Nilsson G, Naukkarinen A, Harvima IT. 2003. Mast cell survival and apoptosis in organ-cultured human skin. EXPERIMENTAL DERMATOLOGY 12 1: 53-60. 2003

Järvikallio A, Harvima IT, Naukkarinen A. 2003. Mast cells, nerves and neuropeptides in atopic dermatitis and nummular eczema ARCHIVES OF DERMATOLOGICAL RESEARCH 295: 2-7. 2003

Hjertson M, Kivinen PK, Dimberg L, Nilsson K, Harvima IT, Nilsson G. 2003. Retinoic acid inhibits in vitro development of mast cells but has no marked effect on mature human skin tryptase- and chymase-positive mast cells. JOURNAL OF INVESTIGATIVE DERMATOLOGY 120 2: 239-245. 2003

Huttunen M, Naukkarinen A, Horsmanheimo M, Harvima IT. 2002. Transient production of stem cell factor in dermal cells but increasing expression of Kit receptor in mast cells during normal wound healing. ARCHIVES OF DERMATOLOGICAL RESEARCH 294 7: 324-330. 2002

Harvima I. 2001. Kroonisten säärihaavojen hoito edellyttää yhteistyötä ja tehokkaita menetelmiä. NOVARTIS NEWS 1: 32-34. 2001

Huttunen M, Hyttinen M, Nilsson G, Butterfield JH, Horsmanheimo M, Harvima IT. 2001. Inhibition of keratinocyte growth in cell culture and whole skin culture by mast cell mediators. EXPERIMENTAL DERMATOLOGY 10 3: 184-192. 2001

Kivinen PK, Kaminska R, Naukkarinen A, Harvima RJ, Horsmanheimo M, Harvima IT. 2001. Release of soluble tryptase but only minor amounts of chymase activity from cutaneous mast cells. EXPERIMENTAL DERMATOLOGY 10: 246-255. 2001

Molin D, Fischer M, Xiang Z, Larsson U, Harvima I, Venge P, Nilsson K, Sundstrom C, Enblad G, Nilsson G. 2001. Mast cells express functional CD30 ligand and are the predominant CD30L-positive cells in Hodgkin's disease. BRITISH JOURNAL OF HAEMATOLOGY 114 3: 616-623. 2001

Saarinen JV, Harvima RJ, Horsmanheimo M, Harvima IT, Naukkarinen A. 2001. Interleukin-4-posituve mast cells are highly associated with the extent of immediate allergic wheal reaction in the skin. ALLERGY 56: 58-64. 2001

Saarinen JV, Harvima RJ, Horsmanheimo M, Harvima IT. 2001. Modulation of the immediate allergic wheal reaction in the skin by drugs inhibiting the effects on leukotriene C4 and prostaglandin D2. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY 57: 1-4. 2001

Saarinen JV, Harvima RJ, Naukkarinen A, Horsmanheimo M, Harvima IT. 2001. The release of histamine is associated with the inactivation of mast cell chymase during immediate allergic wheal reaction in the skin. CLINICAL AND EXPERIMENTAL ALLERGY 31: 593-601. 2001

Taskila K, Saarinen JV, Harvima IT, Harvima RJ. 2000. Histamine and LTC4 in stinging nettle-induced urticaria. ALLERGY 55: 679-680. 2000

Saarinen JV, Harvima RJ, Naukkarinen A, Horsmanheimo M, Harvima IT. 2000. Release of histamine and leukotriene C4 in immendiate allergic wheal reaction as measured with microdialysis techinique. ARCHIVES OF DERMATOLOGICAL RESEARCH 292: 333-340. 2000

Juremalm M, Hjertson M, Olsson N, Harvima I, Nilsson K, Nilsson G. 2000. The chemokine receptor CXCR4 is expressed within the mast cell lineage and its ligand stromal cell-derived factor-1alfa acts as a mast cell chemotaxin. EUROPEAN JOURNAL OF IMMUNOLOGY 30: 3614-3622. 2000

Huttunen M, Aalto M-L, Harvima RJ, Horsmanheimo M, Harvima IT. 2000. Alterations in mast cells showing tryptase and chymase activity in epithelializatingand chronic wounds. EXPERIMENTAL DERMATOLOGY 9: 258-265. 2000

Harvima R, Laukkanen A, Harvima I, Mattila R, Hollmén A. 2000. Lääkkeiden käytön ja ihoreaktioiden kuvauksen sekä kirjaamisen tärkeys myöhemmälle diagnostiikalle. SUOMEN LÄÄKÄRILEHTI 55 20: 2195-2196. 2000

Harvima R, Harvima I. 2000. Kun tutkija yrittää julkaista tutkimuksensa... Kokeneiden tutkijoiden näkökulmia käsikirjoituksen tarjoamisesta tieteelliseen lehteen. LÄÄKÄRISANOMAT 2: 31. 2000

Annila I, Saarinen JV, Nieminen MM, Moilanen E, Hahtola P, Harvima IT. 2000. Bee venom induces high histamine or high leukotriene C4 release in skin of sensitized beekeepers. JOURNAL OF INVESTIGATIONAL ALLERGOLOGY AND CLINICAL IMMUNOLOGY (BARCELONA) 10 4: 223-228. 2000

Ackermann L, Harvima IT, Pelkonen J, Ritamäki-Salo V, Naukkarinen A, Harvima RJ, Horsmanheimo M. 1999. Mast cells in psoriatic skin are strongly positive for interferon-gamma. BRITISH JOURNAL OF DERMATOLOGY 140: 624-633. 1999

Harvima IT, Haapanen L, Ackermann L, Naukkarinen A, Harvima RJ, Horsmanheimo M. 1999. Decreased chymase activity is associated with increased levels of protease inhibitors in mast cells of psoriatic lesions. ACTA DERMATO-VENEREOLOGICA 79: 98-104. 1999

Harvima IT, Virnes S, Kauppinen L, Huttunen M, Kivinen P, Niskanen L, Horsmanheimo M. 1999. Cultured allogeneic skin cells are effective in the treatment of chronic diabetic leg and foot ulcers. ACTA DERMATO-VENEREOLOGICA 79: 217-220. 1999

Harvima RJ, Harvima IT, Dull D, Dunder UK, Schwartz LB. 1999. Identification and characterization of multiple forms of tryptase from human mast cells. ARCHIVES OF DERMATOLOGICAL RESEARCH 291: 73-80. 1999

Harvima RJ, Hollmén A, Mattila R, Kaipiainen-Seppänen O, Harvima IT, Kaminska R, Laukkanen A, Räsänen L, Horsmanheimo M. 1999. Pyoderma gangraenosumin paikallishoito kromoglikaattiliuoksella. DUODECIM 115: 2085-2090. 1999

Kaminska R, Helisalmi P, Harvima RJ, Naukkarinen A, Horsmanheimo M, Harvima IT. 1999. Focal dermal-epidermal separation and fibronectin cleavage in basement membrane by human mast cell tryptase. JOURNAL OF INVESTIGATIVE DERMATOLOGY 113: 567-573. 1999

Kaminska R, Naukkarinen A, Glinski W, Horsmanheimo M, Harvima IT. 1999. Mast cells in developing subepidermal bullous diseases: emphasis on tryptase, chymase and protease inhibitors ACTA DERMATO-VENEREOLOGICA 79: 351-355. 1999

Kaminska R, Naukkarinen A, Horsmanheimo M, Harvima IT. 1999. Suction blister formation in skin after acute and repeated mast cell degranulation. ACTA DERMATO-VENEREOLOGICA 79: 191-194. 1999

Kivinen PK, Hyttinen M, Harvima RJ, Naukkarinen A, Horsmanheimo M, Harvima IT. 1999. Quantitative digital image analysis applied to demonstrate the stratified distribution of involucrin in organ cultured human skin. ARCHIVES OF DERMATOLOGICAL RESEARCH 291: 217-223. 1999

Vaahtoranta-Lehtonen HH, Lehtonen OP, Harvima I, Peltola O, Nikoskelainen E. 1999. Papillary hypertrophy of the upper tarsal conjunctiva during contact lens wear: a 4-month study with ethyl-6-O-decanoyl-glucoside. CLAO JOURNAL 25 2: 105-108. 1999

Harvima I. 1998. Diabeetikon jalkahaavaumien uudet aktiivisemmat hoitomuodot. DIABETES JA LÄÄKÄRI 4: 8-16. 1998

Ackermann L, Pelkonen J, Harvima IT. 1998. Staphylococcal enterotoxin B inhibits the production of interleukin-4 in a human mast-cell line HMC-1 IMMUNOLOGY 94: 247-252. 1998

Ackermann L, Harvima IT. 1998. Mast cells of psoriatic and atopic dermatitis skin are positive for TNF-alpha and their degranulation is associated with expression of ICAM-1 in the epidermis. ARCHIVES OF DERMATOLOGICAL RESEARCH 290: 353-359. 1998

Järvikallio A, Naukkarinen A, Harvima IT, Aalto M-L, Horsmanheimo M. 1997. Quantitative analysis of tryptase- and chymase-containing mast cells in atopic dermatitis and nummular eczema. BRITISH JOURNAL OF DERMATOLOGY 136: 871-877. 1997

Kankkunen J-P, Harvima IT, Naukkarinen A. 1997. Quantitative analysis of tryptase and chymase containing mast cells in benign and malignant breast lesions INTERNATIONAL JOURNAL OF CANCER 72: 385-388. 1997

Nilsson G, Blom T, Harvima I, Kusche-Gullberg M, Nilsson K, Hellman L. 1996. Stem cell factor-dependent human cord blood derived mast cells express alpha- and beta-tryptase, heparin and chondroitin sulphate. IMMUNOLOGY 88: 308-314. 1996

Naukkarinen A, Järvikallio A, Lakkakorpi J, Harvima IT, Harvima RJ, Horsmanheimo M. 1996. Quantitative histochemical analysis of mast cells and sensory nerves in psoriatic skin JOURNAL OF PATHOLOGY 180: 200-205. 1996

Kaminska R, Harvima IT, Naukkarinen A, Nilsson G, Horsmanheimo M. 1996. Alterations in mast cell proteinases and protease inhibitors in the progress of cutaneous herpes zoster infection. JOURNAL OF PATHOLOGY 180: 434-440. 1996

Härmä M, Ruokonen E, Harvima I, Takala J. 1996. Palovammojen hoito. DUODECIM 112: 1455-1462. 1996

Huttunen M, Harvima IT, Ackermann L, Harvima RJ, Naukkarinen A, Horsmanheimo M. 1996. Neuropeptide- and capsaicin-induced histamine release in skin monitored with the microdialysis technique. ACTA DERMATO-VENEREOLOGICA 76: 205-209. 1996

Horsmanheimo L, Harvima IT, Harvima RJ, Ylönen J, Naukkarinen A, Horsmanheimo M. 1996. Histamine release in skin monitored with the mikrodialysis technique does not correlate with the weal size induced by cow allergen. BRITISH JOURNAL OF DERMATOLOGY 134: 94-100. 1996

Horsmanheimo L, Harvima IT, Harvima RJ, Brummer-Korvenkontio H, Francois G, Reunala T. 1996. Histamine and leukotriene C4 release in cutaneous mosquito-bite reactions. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 98 2: 408-411. 1996

Harvima RJ, Viinamäki H, Harvima IT, Naukkarinen A, Savolainen L, Aalto M-L, Horsmanheimo M. 1996. Association of psychic stress with clinical severity and symptoms of psoriatic patients ACTA DERMATO-VENEREOLOGICA 76: 467-471. 1996

Harvima R, Harvima I. 1996. Kun nuori nainen valittaa tukan lähtöä. SUOMEN LÄÄKÄRILEHTI 51 16: 1799-1801. 1996

Harvima IT, Harvima RJ, Naukkarinen A, Horsmanheimo M. 1995. Skin tryptase: Features and expression in human dermatological disorders: Caughey GH, Mast Cell Proteases in Immunology and Biology.Marcel Dekker. Clinical Allergy and Immunology. 25-46. 1995

Welle MM, Proske SM, Harvima IT, Schechter NM. 1995. Demonstration of tryptase in bovine cutaneous and tumor mast cells. JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY 43 11: 1139-1144. 1995

Harvima IT, Horsmanheimo L, Naukkarinen A, Horsmanheimo M. 1994. Mast cell proteinases and cytokines in skin inflammation. ARCHIVES OF DERMATOLOGICAL RESEARCH 287: 61-67. 1994

Horsmanheimo L, Harvima IT, Järvikallio A, Harvima RJ, Naukkarinen A, Horsmanheimo M. 1994. Mast cells are one major source of interleukin-4 in atopic dermatitis. BRITISH JOURNAL OF DERMATOLOGY 131: 348-353. 1994

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