I completed my PhD in Human Nutrition, minor in Molecular Biology & Biotechnology at the University of the Philippines joined with Colorado State University, USA. My PhD research focused on identification of dietary biomarkers in cereal bran using metabolomics from two human intervention studies in adults and children and determination of cereal bran property in inhibiting bacterial pathogenicity in mouse cell line. As my cognate was Molecular Biology & Biotechnology, during my PhD program, I also worked over three years as lar at the Grain Quality and Nutrition Center as well as the Genetic Transformation Laboratory of the International Rice Research Institute (IRRI) in the Philippines, the most renowned rice research organization in the world. My work at IRRI included rice metabolomics, identification rice varieties with high protein content, and genetic modifications of rice for vitamin A (Golder Rice project) and iron and zinc bio-fortification. I currently work within the LongITools project (https://longitools.org) to study the effects physical activity and diet exposures on human health in determining the risks of chronic cardiovascular and metabolic diseases.
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Eight-year Diet and Physical Activity Intervention Affects Serum Metabolites during Childhood & Adolescence: A Nonrandomized Controlled Trial
Zarei, Iman; Eloranta, Aino-Maija; Klåvus, Anton; Väistö, Juuso; Lehtonen, Marko; Mikkonen, Santtu; Koistinen, Ville M; Sallinen, Taisa; Haapala, Eero A; Lintu, Niina; Soininen, Sonja; Haikonen, Retu; Atalay, Mustafa; Schwab, Ursula; Auriola, Seppo; Kolehmainen, Marjukka; Hanhineva, Kati; Lakka, Timo A. 2024. iScience. 27: A1 Journal article (refereed), original research -
Longitudinal associations of an exposome score with serum metabolites from childhood to adolescence
Healy, Darren R; Zarei, Iman; Mikkonen, Santtu; Soininen, Sonja; Viitasalo, Anna; Haapala, Eero A; Auriola, Seppo; Hanhineva, Kati; Kolehmainen, Marjukka; Lakka, Timo A. 2024. Communications biology. 7: . 890 A1 Journal article (refereed), original research -
Identification and Distribution of Sterols, Bile Acids, and Acylcarnitines by LC–MS/MS in Humans, Mice, and Pigs—A Qualitative Analysis
Babu, Ambrin Farizah; Koistinen, Ville Mikael; Turunen, Soile; Solano-Aguilar, Gloria; Urban, Joseph F.; Zarei, Iman; Hanhineva, Kati. 2022. Metabolites. 12: A1 Journal article (refereed), original research -
LongITools: Dynamic longitudinal exposome trajectories in cardiovascular and metabolic noncommunicable diseases
Ronkainen, Justiina; Nedelec, Rozenn; Atehortua, Angelica; Balkhiyarova, Zhanna; Cascarano, Anna; Ngoc Dang, Vien; Elhakeem, Ahmed; van Enckevort, Esther; Goncalves Soares, Ana; Haakma, Sido; Halonen, Miia; Heil, Katharina F.; Heiskala, Anni; Hyde, Eleanor; Jacquemin, Bénédicte; Keikkala, Elina; Kerckhoffs, Jules; Klåvus, Anton; Kopinska, Joanna A.; Lepeule, Johanna; Marazzi, Francesca; Motoc, Irina; Näätänen, Mari; Ribbenstedt, Anton; Rundblad, Amanda; Savolainen, Otto; Simonetti, Valentina; de. 2022. Environmental epidemiology. 6: A1 Journal article (refereed), original research -
Tissue-wide metabolomics reveals wide impact of gut microbiota on mice metabolite composition
Zarei, Iman; Koistinen, Ville M.; Kokla, Marietta; Klåvus, Anton; Babu, Ambrin Farizah; Lehtonen, Marko; Auriola, Seppo; Hanhineva, Kati. 2022. Scientific reports. 12: . 15018 A1 Journal article (refereed), original research -
"notame": Workflow for Non-Targeted LC-MS Metabolic Profiling
Klåvus, Anton; Kokla, Marietta; Noerman, Stefania; Koistinen, Ville M; Tuomainen, Marjo; Zarei, Iman; Meuronen, Topi; Häkkinen, Merja R; Rummukainen, Soile; Farizah Babu, Ambrin; Sallinen, Taisa; Kärkkäinen, Olli; Paananen, Jussi; Broadhurst, David; Brunius, Carl; Hanhineva, Kati. 2020. Metabolites. 10: 135 A1 Journal article (refereed), original research -
Contribution of gut microbiota to metabolism of dietary glycine betaine in mice and in vitro colonic fermentation
Koistinen, VM; Kärkkäinen, O; Borewicz, K; Zarei, I; Jokkala, J; Micard, V; Rosa-Sibakov, N; Auriola, S; Aura, AM; Smidt, H; Hanhineva, K. 2019. Microbiome. 7: 103 A1 Journal article (refereed), original research