Janne Mäkelä
Academy Research Fellow
Contrast media and biolubricants for early diagnosis and treatment of osteoarthritis.
Department of Technical Physics, Faculty of Science, Forestry and Technology
janne.makela@uef.fi | +358 50 477 1708
Currently interested in contrast media and biolubricants in the early diagnosis and treatment of osteoarthritis. What is the potential of new contrast media in imaging of articular cartilage? How do you best use radiographic imaging to monitor the progression of osteoarthritis over time, and how does a synthetic biopolymer, that lubricates and reinforces the tissue, slow down the disease progression?
Group website
Research groups
Publications
43/43 items-
3-D T1 relaxation time measurements in an equine model of subtle post-traumatic osteoarthritis using MB-SWIFT
Pala, Swetha; Hänninen, Nina E; Mohammadi, Ali; Ebrahimi, Mohammadhossein; te Moller, Nikae CR; Brommer, Harold; René van Weeren, P; Mäkelä, Janne TA; Korhonen, Rami K; Afara, Isaac O; Töyräs, Juha; Mikkonen, Santtu; Nissi, Mikko J; Nykänen, Olli. 2023. Journal of orthopaedic research. 41: 2657-2666 -
Cationic tantalum oxide nanoparticle contrast agent for micro computed tomography reveals articular cartilage proteoglycan distribution and collagen architecture alterations
Jäntti, Jiri; Joenathan, Anisha; Fugazzola, Maria; Tuppurainen, Juuso; Honkanen, Juuso TJ; Töyräs, Juha; van Weeren, René; Snyder, Brian D; Grinstaff, Mark W; Matikka, Hanna; Mäkelä, Janne TA. 2023. Osteoarthritis and cartilage. 2024; 32: 299-309 -
Composition, architecture and biomechanical properties of articular cartilage in differently loaded areas of the equine stifle
Fugazzola, Maria; Nissinen, Mikko T; Jäntti, Jiri; Tuppurainen, Juuso; Plomp, Saskia; Te Moller, Nikae; Mäkelä, Janne TA; van Weeren, Rene. 2023. Equine veterinary journal. [Epub ahead of print 27 June 2023]: 1-13 -
Contrast Agent Diffusion Reflects Biomechanical Finite Element Model Properties Of Articular Cartilage
Tuppurainen, J..; Jäntti, J.; Nissinen, M.T.; Fugazzola, M.C.; van Weeren, R.; Joenathan, A.; Grinstaff, M.W.; Matikka, H.; Korhonen, R.K.; Mäkelä, J.T.. 2023. Osteoarthritis and cartilage -
Near-infrared spectroscopic assessment of patellar tendon mechanics
Kositsky, Adam; Torniainen, Jari; Stenroth, Lauri; Nippolainen, Ervin; Mäkelä, Janne T.A.; Paakkari, Petri; Kröger, Heikki; Töyräs, Juha; Korhonen, Rami K.; Afara, Isaac O.. 2023. -
Patellar tendon and tibial cartilage viscoelastic properties are inversely related in osteoarthritic knees
Kositsky, Adam; Linus, Awuniji; Stenroth, Lauri; Mononen, Mika E.; Nippolainen, Ervin; Kröger, Heikki; Töyräs, Juha; Mäkelä, Janne T.A.; Tanska, Petri; Afara, Isaac O.; Korhonen, Rami K.. 2023. Transactions of the annual meeting of the Orthopaedic Research Society -
Tantalum And Iodine Based Dual-Contrast Photon-Counting Computed Tomography Method For Assessment Of Articular Cartilage Composition
Paakkari, P.; Inkinen, S.I.; Jäntti, J.; Tuppurainen, J.; Fugazzola, M.C.; Joenathan, A.; Ylisiurua, S.; Nieminen, M.T.; Grinstaff, M.W.; Kröger, H.; Töyräs, J.; Honkanen, J.T.; Mäkelä, J.T.. 2023. Osteoarthritis and cartilage -
Triple contrast computed tomography reveals site‐specific biomechanical differences in human knee joint – a proof of concept study
Orava, Heta; Paakkari, Petri; Jäntti, Jiri; Honkanen, Miitu KM; Honkanen, Juuso TJ; Virén, Tuomas; Joenathan, Anisha; Tanska, Petri; Korhonen, Rami K; Grinstaff, Mark W; Töyräs, Juha; Mäkelä, Janne TA. 2023. Journal of orthopaedic research. 2024; 42: 415-424 -
Visible and Near-Infrared Spectroscopy Enables Differentiation of Normal and Early Osteoarthritic Human Knee Joint Articular Cartilage
Linus, Awuniji; Tanska, Petri; Sarin, Jaakko K.; Nippolainen, Ervin; Tiitu, Virpi; Mäkelä, Janne T.A.; Töyräs, Juha; Korhonen, Rami K.; Mononen, Mika E.; Afara, Isaac O.. 2023. Annals of biomedical engineering. 51: 2245-2257 -
Changes in subchondral bone structure and mechanical properties do not substantially affect cartilage mechanical responses – A finite element study
Orava, Heta; Huang, Lingwei; Ojanen, Simo P; Mäkelä, Janne TA; Finnilä, Mikko AJ; Saarakkala, Simo; Herzog, Walter; Korhonen, Rami K; Töyräs, Juha; Tanska, Petri. 2022. Journal of the mechanical behavior of biomedical materials. 128: