![Janne Mäkelä](https://uefconnect.uef.fi/wp-content/uploads/2019/04/408e70309d9723fed5f7051983b62525_profile_file-500x500.jpg)
Janne Mäkelä
Academy Research Fellow
Contrast media and biolubricants for early diagnosis and treatment of osteoarthritis.
Department of Technical Physics, Faculty of Science, Forestry and Technology
janne.makela@uef.fi | +358 50 477 1708
Currently interested in contrast media and biolubricants in the early diagnosis and treatment of osteoarthritis. What is the potential of new contrast media in imaging of articular cartilage? How do you best use radiographic imaging to monitor the progression of osteoarthritis over time, and how does a synthetic biopolymer, that lubricates and reinforces the tissue, slow down the disease progression?
Group website
Research groups
Publications
49/49 items-
Advances in viscosupplementation and tribosupplementation for early-stage osteoarthritis therapy
DeMoya, Christian D; Joenathan, Anisha; Lawson, Taylor B; Felson, David T; Schaer, Thomas P; Bais, Manish; Albro, Michael B; Mäkelä, Janne; Snyder, Brian D; Grinstaff, Mark W. 2024. Nature reviews rheumatology. 20: 432-451 -
Longitudinal in vivo cationic contrast-enhanced computed tomography classifies equine articular cartilage injury and repair
Nelson, Brad B.; Mäkelä, Janne T. A.; Lawson, Taylor B.; Patwa, Amit N.; Snyder, Brian D.; Mcilwraith, C. Wayne; Grinstaff, Mark W.; Seabaugh, Kathryn A.; Barrett, Myra F.; Goodrich, Laurie R.; Kawcak, Christopher E.. 2024. Journal of orthopaedic research. [Epub ahead of print 8 May 2024]: 1-13 -
Revealing Detailed Cartilage Function Through Nanoparticle Diffusion Imaging: A Computed Tomography & Finite Element Study
Tuppurainen, Juuso; Paakkari, Petri; Jäntti, Jiri; Nissinen, Mikko T. Fugazzola, Maria C; van Weeren, René; Ylisiurua, Sampo; Nieminen, Miika T; Kröger, Heikki; Snyder, Brian D; Joenathan, Anisha; Grinstaff, Mark W; Matikka, Hanna; Korhonen, Rami K; Mäkelä, Janne TA. 2024. Annals of biomedical engineering. [Epub ahead of print 16 July 2024]: 1-12 -
3-D T1 relaxation time measurements in an equine model of subtle post-traumatic osteoarthritis using MB-SWIFT
Pala, Swetha; Hänninen, Nina E; Mohammadi, Ali; Ebrahimi, Mohammadhossein; te Moller, Nikae CR; Brommer, Harold; René van Weeren, P; Mäkelä, Janne TA; Korhonen, Rami K; Afara, Isaac O; Töyräs, Juha; Mikkonen, Santtu; Nissi, Mikko J; Nykänen, Olli. 2023. Journal of orthopaedic research. 41: 2657-2666 -
Articular Cartilage Characterization Using Tantalum and Iodine-based Dual-Contrast Photon-Counting Computed Tomography
Paakkari, Petri; Inkinen, Satu; Jäntti, Jiri; Tuppurainen, Juuso; Fugazzola, Maria; Joenathan, Anisha; Ylisiurua, Sampo; Nieminen, Miika; Grinstaff, Mark; Kröger, Heikki; Töyräs, Juha; Honkanen, Juuso; Mäkelä, Janne. 2023. Transactions of the annual meeting of the Orthopaedic Research Society -
Cationic tantalum oxide nanoparticle contrast agent for micro computed tomography reveals articular cartilage proteoglycan distribution and collagen architecture alterations
Jäntti, Jiri; Joenathan, Anisha; Fugazzola, Maria; Tuppurainen, Juuso; Honkanen, Juuso TJ; Töyräs, Juha; van Weeren, René; Snyder, Brian D; Grinstaff, Mark W; Matikka, Hanna; Mäkelä, Janne TA. 2023. Osteoarthritis and cartilage. 2024; 32: 299-309 -
Composition, architecture and biomechanical properties of articular cartilage in differently loaded areas of the equine stifle
Fugazzola, Maria; Nissinen, Mikko T; Jäntti, Jiri; Tuppurainen, Juuso; Plomp, Saskia; Te Moller, Nikae; Mäkelä, Janne TA; van Weeren, Rene. 2023. Equine veterinary journal. 2024; 56: 573-585 -
Contrast Agent Diffusion Reflects Biomechanical Finite Element Model Properties Of Articular Cartilage
Tuppurainen, J; Jäntti, J; Nissinen, MT; Fugazzola, MC; van Weeren, R; Joenathan, A; Grinstaff, MW; Matikka, H; Korhonen, RK; Mäkelä, JT. 2023. Osteoarthritis and cartilage -
Effect Of Depth-dependent Variation In Articular Cartilage Composition On Nanoparticle Diffusion
Jäntti, Jiri; Joenathan, Anisha; Fugazzola, Maria C; van Weeren, René; Synder, Brian D; Grinstaff, Mark W; Töyräs, Juha; Matikka, Hanna; Mäkelä, Janne TA. 2023. Transactions of the annual meeting of the Orthopaedic Research Society -
Near-infrared spectroscopic assessment of patellar tendon mechanics
Kositsky, Adam; Torniainen, Jari; Stenroth, Lauri; Nippolainen, Ervin; Mäkelä, Janne TA; Paakkari, Petri; Kröger, Heikki; Töyräs, Juha; Korhonen, Rami K; Afara, Isaac O. 2023.