Janne Mäkelä
Academy Research Fellow
Contrast media and biolubricants for early diagnosis and treatment of osteoarthritis.
Department of Technical Physics, Faculty of Science, Forestry and Technology
janne.makela@uef.fi | +358 50 477 1708
Currently interested in contrast media and biolubricants in the early diagnosis and treatment of osteoarthritis. What is the potential of new contrast media in imaging of articular cartilage? How do you best use radiographic imaging to monitor the progression of osteoarthritis over time, and how does a synthetic biopolymer, that lubricates and reinforces the tissue, slow down the disease progression?
Research groups
Publications
40 items-
3-D T1 relaxation time measurements in an equine model of subtle post-traumatic osteoarthritis using MB-SWIFT
Pala, Swetha; Hänninen, Nina E; Mohammadi, Ali; Ebrahimi, Mohammadhossein; te Moller, Nikae CR; Brommer, Harold; René van Weeren, P; Mäkelä, Janne TA; Korhonen, Rami K; Afara, Isaac O; Töyräs, Juha; Mikkonen, Santtu; Nissi, Mikko J; Nykänen, Olli. 2023. Journal of orthopaedic research. 41: 2657-2666 -
Composition, architecture and biomechanical properties of articular cartilage in differently loaded areas of the equine stifle
Fugazzola, Maria; Nissinen, Mikko T; Jäntti, Jiri; Tuppurainen, Juuso; Plomp, Saskia; Te Moller, Nikae; Mäkelä, Janne TA; van Weeren, Rene. 2023. Equine veterinary journal. [Epub ahead of print 27 June 2023]: 1-13 -
Near-infrared spectroscopic assessment of patellar tendon mechanics
Kositsky, Adam; Torniainen, Jari; Stenroth, Lauri; Nippolainen, Ervin; Mäkelä, Janne T.A.; Paakkari, Petri; Kröger, Heikki; Töyräs, Juha; Korhonen, Rami K.; Afara, Isaac O.. 2023. -
Patellar tendon and tibial cartilage viscoelastic properties are inversely related in osteoarthritic knees
Kositsky, Adam; Linus, Awuniji; Stenroth, Lauri; Mononen, Mika E.; Nippolainen, Ervin; Kröger, Heikki; Töyräs, Juha; Mäkelä, Janne T.A.; Tanska, Petri; Afara, Isaac O.; Korhonen, Rami K.. 2023. Transactions of the annual meeting of the Orthopaedic Research Society -
Triple contrast computed tomography reveals site‐specific biomechanical differences in human knee joint – a proof of concept study
Orava, Heta; Paakkari, Petri; Jäntti, Jiri; Honkanen, Miitu KM; Honkanen, Juuso TJ; Virén, Tuomas; Joenathan, Anisha; Tanska, Petri; Korhonen, Rami K; Grinstaff, Mark W; Töyräs, Juha; Mäkelä, Janne TA. 2023. Journal of orthopaedic research. [Epub ahead of print: 30 August 2023]: 1-10 -
Visible and Near-Infrared Spectroscopy Enables Differentiation of Normal and Early Osteoarthritic Human Knee Joint Articular Cartilage
Linus, Awuniji; Tanska, Petri; Sarin, Jaakko K.; Nippolainen, Ervin; Tiitu, Virpi; Mäkelä, Janne T.A.; Töyräs, Juha; Korhonen, Rami K.; Mononen, Mika E.; Afara, Isaac O.. 2023. Annals of biomedical engineering. 51: 2245-2257 -
Changes in subchondral bone structure and mechanical properties do not substantially affect cartilage mechanical responses – A finite element study
Orava, Heta; Huang, Lingwei; Ojanen, Simo P; Mäkelä, Janne TA; Finnilä, Mikko AJ; Saarakkala, Simo; Herzog, Walter; Korhonen, Rami K; Töyräs, Juha; Tanska, Petri. 2022. Journal of the mechanical behavior of biomedical materials. 128: -
Dual‐contrast micro‐CT enables cartilage lesion detection and tissue condition evaluation ex vivo
Honkanen, Miitu KM; Mohammadi, Ali; te Moller, Nikae CR; Ebrahimi, Mohammadhossein; Xu, Wujun; Plomp, Saskia; Pouran, Behdad; Lehto, Vesa‐Pekka; Brommer, Harold; van Weeren, P René; Korhonen, Rami K; Töyräs, Juha; Mäkelä, Janne TA. 2022. Equine veterinary journal. 2023; 55: 315-324 -
Elastic and viscoelastic human patellar tendon regional properties
Kositsky, Adam; Stenroth, Lauri; Nippolainen, Ervin; Mäkelä, Janne; Paakkari, Petri; Torniainen, Jari; Kröger, Heikki; Afara, Isaac; Korhonen, Rami. 2022. -
Site- and Zone-Dependent Changes in Proteoglycan Content and Biomechanical Properties of Bluntly and Sharply Grooved Equine Articular Cartilage
Mohammadi, Ali; te Moller, Nikae C. R.; Ebrahimi, Mohammadhossein; Plomp, Saskia; Brommer, Harold; van Weeren, P. René; Mäkelä, Janne T. A.; Töyräs, Juha; Korhonen, Rami K.. 2022. Annals of biomedical engineering. 50: 1787–1797