Janne Mäkelä
Academy Research Fellow
Contrast media and biolubricants for early diagnosis and treatment of osteoarthritis.
Department of Technical Physics, Faculty of Science, Forestry and Technology
[email protected] | +358 50 477 1708
Currently interested in contrast media and biolubricants in the early diagnosis and treatment of osteoarthritis. What is the potential of new contrast media in imaging of articular cartilage? How do you best use radiographic imaging to monitor the progression of osteoarthritis over time, and how does a synthetic biopolymer, that lubricates and reinforces the tissue, slow down the disease progression?
Group website
Research groups
Publications
53/53 items-
Dual-Contrast Agent with Nanoparticle and Molecular Components in Photon-Counting Computed Tomography: Assessing Articular Cartilage Health
Paakkari, Petri; Inkinen, Satu I; Jäntti, Jiri; Tuppurainen, Juuso; Fugazzola, Maria C; Joenathan, Anisha; Ylisiurua, Sampo; Nieminen, Miika T; Kröger, Heikki; Mikkonen, Santtu; van Weeren, René; Snyder, Brian D; Töyräs, Juha; Honkanen, Miitu KM; Matikka, Hanna; Grinstaff, Mark W; Honkanen, Juuso TJ; Mäkelä, Janne TA. 2025. Annals of biomedical engineering. 53: 1423-1438 A1 Journal article (refereed), original research -
Orientation-Independent T2 Mapping Enhances MRI-Based Cartilage Characterization
Leskinen, Henri P P; Tuppurainen, Juuso; Jäntti, Jiri; Mäkelä, Janne T A; Nippolainen, Ervin; Afara, Isaac O; Töyräs, Juha; Nykänen, Olli; Nissi, Mikko J. 2025. Annals of biomedical engineering. [Epub ahead of print 17 June 2025]: 1-11 A1 Journal article (refereed), original research -
Relationships between human patellar tendon and tibial cartilage viscoelastic properties in osteoarthritic knees: an exploratory investigation
Kositsky, Adam; Linus, Awuniji; Stenroth, Lauri; Nippolainen, Ervin; Kröger, Heikki; Töyräs, Juha; Mäkelä, Janne TA; Liukkonen, Mimmi K; Tanska, Petri; Afara, Isaac O; Mononen, Mika E; Korhonen, Rami K. 2025. Journal of biomechanics. 189: A1 Journal article (refereed), original research -
The human patellar tendon is mechanically homogenous at its mid-substance
Kositsky, Adam; Stenroth, Lauri; Nippolainen, Ervin; Torniainen, Jari; Mäkelä, Janne TA; Paakkari, Petri; Paakkonen, Tommi; Kröger, Heikki; Töyräs, Juha; Afara, Isaac O; Korhonen, Rami K. 2025. Journal of the mechanical behavior of biomedical materials. 163: A1 Journal article (refereed), original research -
Advances in viscosupplementation and tribosupplementation for early-stage osteoarthritis therapy
DeMoya, Christian D; Joenathan, Anisha; Lawson, Taylor B; Felson, David T; Schaer, Thomas P; Bais, Manish; Albro, Michael B; Mäkelä, Janne; Snyder, Brian D; Grinstaff, Mark W. 2024. Nature reviews rheumatology. 20: 432-451 A2 Review article, Literature review, Systematic review -
Comparison of site-specific tensile, compressive, and friction properties of human tibiofemoral joint cartilage and their relationship to degeneration
Ristaniemi, Aapo; Tuppurainen, Juuso; Jäntti, Jiri; Nippolainen, Ervin; Afara, Isaac O; Mononen, Mika E; Korhonen, Rami K; Mäkelä, Janne TA. 2024. Journal of biomechanics. 177: A1 Journal article (refereed), original research -
Longitudinal in vivo cationic contrast-enhanced computed tomography classifies equine articular cartilage injury and repair
Nelson, Brad B; Mäkelä, Janne T A; Lawson, Taylor B; Patwa, Amit N; Snyder, Brian D; Mcilwraith, C Wayne; Grinstaff, Mark W; Seabaugh, Kathryn A; Barrett, Myra F; Goodrich, Laurie R; Kawcak, Christopher E. 2024. Journal of orthopaedic research. 42: 2264-2276 A1 Journal article (refereed), original research -
Photon-counting in dual-contrast-enhanced computed tomography: a proof-of-concept quantitative biomechanical assessment of articular cartilage
Paakkari, Petri; Inkinen, Satu I; Mohammadi, Ali; Nieminen, Miika T; Joenathan, Anisha; Grinstaff, Mark W; Töyräs, Juha; Mäkelä, Janne TA; Honkanen, Juuso TJ. 2024. Scientific reports. 14: . 29956 A1 Journal article (refereed), original research -
Raman Spectra Predict the Composition, Structure, and Viscoelastic Properties of Articular Cartilage
Kazemi, Masumeh; Tuppurainen, Juuso; Jäntti, Jiri; Yu, Chenhao; Fugazzola, Maria; Van Weeren, René; Grinstaff, Mark W; Snyder, Brian D; Bergholt, Mads S; Mäkelä, Janne; Albro, Michael B. 2024. Transactions of the annual meeting of the Orthopaedic Research Society abstract -
Revealing Detailed Cartilage Function Through Nanoparticle Diffusion Imaging: A Computed Tomography & Finite Element Study
Tuppurainen, Juuso; Paakkari, Petri; Jäntti, Jiri; Nissinen, Mikko T. Fugazzola, Maria C; van Weeren, René; Ylisiurua, Sampo; Nieminen, Miika T; Kröger, Heikki; Snyder, Brian D; Joenathan, Anisha; Grinstaff, Mark W; Matikka, Hanna; Korhonen, Rami K; Mäkelä, Janne TA. 2024. Annals of biomedical engineering. 52: 2584-2595 A1 Journal article (refereed), original research