JONNA NISKANEN

Early Stage Researcher

We are utilizing hiPSC cells to model Parkinson's disease (LRRK2 G2019S-mutation). My focus is in PD related neuroinflammation and glial cells, microglia and astrocytes.

Contact info

Organization

Faculty of Health Sciences, A.I. Virtanen Institute for Molecular Sciences

Email

jonna.niskanen@uef.fi

Phone

Keywords

astrocytes cell culturing glial cells Parkinson's disease

Research groups and research projects

2021-

Sarka Lehtonen: Human Brain Disease Modeling

2019-2021

Paavo Honkakoski: EDCMET

Optimizing and validating reporter gene assays for regulatory purposes to detect hormone disrupting substances. Focus on nuclear receptor signaling.

Research groups - UEF

Human Brain Disease Modelling (Lehtonen lab)

Publications

Saran, Chitra; Sundqvist, Louise; Ho, Henry; Niskanen, Jonna; Honkakoski, Paavo; Brouwer, Kim LR. 2022. Novel Bile Acid-dependent Mechanisms of Hepatotoxicity Associated with Tyrosine Kinase Inhibitors Journal of pharmacology and experimental therapeutics 380 2: 114-125. 2022
Albert, Katrina; Niskanen, Jonna; Kälvälä, Sara; Lehtonen, Šárka. 2021. Utilising Induced Pluripotent Stem Cells in Neurodegenerative Disease Research: Focus on Glia International journal of molecular sciences 22 9: 4334. 2021
Küblbeck, Jenni; Niskanen, Jonna; Honkakoski, Paavo. 2020. Metabolism-Disrupting Chemicals and the Constitutive Androstane Receptor CAR Cells 9 10: 2306. 2020
Küblbeck, Jenni; Vuorio, Taina; Niskanen, Jonna; Fortino, Vittorio; Braeunin, Albert; Abass, Khaled; Rautio, Arja; Hakkola, Jukka; Honkakoski, Paavo; Levonen, Anna-Liisa. 2020. The EDCMET project: Metabolic effects of endocrine disruptors International journal of molecular sciences 21 8: 3021. 2020