Kaisa Paldanius
Coordinator
Coordinator, Brain Research Unit. Responsibilities include coordination of Brain Research Unit activities in EU-funded research projects related to aging and dementia risk reduction, e.g. AD-RIDDLE, PROMINENT and 2D-BioPAD (Horizon, IHI)
Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences
kaisa.paldanius@uef.fi | +358 50 439 2580
Kaisa Paldanius is a Doctor of Philosophy (biochemistry, molecular neurobiology) who is the scientific coordinator of international EU-funded research projects on ageing and dementia risk prevention: AD-RIDDLE, Prominent and 2D-BioPAD. Kaisa has over 20 years of experience in academic research as well as preclinical phase research in a global CRO company. She utilizes these skills in a variety of development and communication tasks at the Brain Research Unit.
Publications
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Presynaptic Vesicle Protein SEPTIN5 Regulates the Degradation of APP C-Terminal Fragments and the Levels of Aß
Marttinen, Mikael; Ferreira, Catarina B; Paldanius, Kaisa M A; Takalo, Mari; Natunen, Teemu; Mäkinen, Petra; Leppänen, Luukas; Leinonen, Ville; Tanigaki, Kenji; Kang, Gina; Hiroi, Noboru; Soininen, Hilkka; Rilla, Kirsi; Haapasalo, Annakaisa; Hiltunen, Mikko. 2020. Cells. 9: 2482 -
Dynamics of clusterin protein expression in the brain and plasma following experimental traumatic brain injury
Das Gupta, S; Lipponen, A; Paldanius, KMA; Puhakka, N; Pitkänen, A. 2019. Scientific reports. 9: 20208 -
Using online game-based platforms to improve student performance and engagement in histology teaching
Felszeghy, S; Pasonen-Seppänen, S; Koskela, A; Nieminen, P; Härkönen, K; Paldanius, KMA; Gabbouj, S; Ketola, K; Hiltunen, M; Lundin, M; Haapaniemi, T; Sointu, E; Bauman, EB; Gilbert, GE; Morton, D; Mahonen, A. 2019. Bmc medical education. 19: 273 -
A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology
Marttinen, M; Paananen, J; Neme, A; Mitra, V; Takalo, M; Natunen, T; Paldanius, KMA; Mäkinen, P; Bremang, M; Kurki, MI; Rauramaa, T; Leinonen, V; Soininen, H; Haapasalo, A; Pike, I; Hiltunen, M. 2018. Neurobiology of disease. 2019; 124: 454-468 -
Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice
Gabbouj, S; Natunen, T; Koivisto, H; Jokivarsi, K; Takalo, M; Marttinen, M; Wittrahm, R; Kemppainen, S; Naderi, R; Posado-Fernández, A; Ryhänen, S; Mäkinen, P; Paldanius, KMA; Doria, G; Poutiainen, P; Flores, O; Haapasalo, A; Tanila, H; Hiltunen, M. 2018. Neurobiology of aging. 2019; 75: 98-108 -
Protein kinase C -activating isophthalate derivatives mitigate Alzheimer's disease-related cellular alterations
Sarajärvi, T; Jäntti, M; Paldanius, KMA; Natunen, T; Wu, JC; Mäkinen, P; Tarvainen, I; Tuominen, RK; Talman, V; Hiltunen, M. 2018. Neuropharmacology. 141: 76-88 -
Behavioral testing of mice exposed to intermediate frequency magnetic fields indicates mild memory impairment
Kumari K, Koivisto H, Viluksela M, Paldanius KMA, Marttinen M, Hiltunen M, Naarala J, Tanila H, Juutilainen J. 2017. PLoS ONE. 12: e0188880 -
DHCR24 exerts neuroprotection upon inflammation-induced neuronal death
Martiskainen H, Paldanius KMA, Natunen T, Takalo M, Marttinen M, Leskelä S, Huber N, Mäkinen P, Bertling E, Dhungana H, Huuskonen M, Honkakoski P, Hotulainen P, Rilla K, Koistinaho J, Soininen H, Malm T, Haapasalo A, Hiltunen M. 2017. Journal of neuroinflammation. : 215 -
New Implications for the Role for Ubiquilin-1 in Molecular Mechanisms of Alzheimer's Disease: Interrelationship with BACE1
Takalo Mari, Natunen Teemu, Leskelä Stina, Paldanius Kaisa MA, Soininen Hilkka, Hiltunen MIkko, Haapasalo Annakaisa. 2017. Journal of Alzheimer's disease & Parkinsonism. 7: 365 -
Effects of Alzheimer's Disease-Associated Risk Loci on Cerebrospinal Fluid Biomarkers and Disease Progression: A Polygenic Risk Score Approach
Martiskainen Henna, Helisalmi Seppo, Viswanathan Jayashree, Kurki Mitja, Hall Anette, Herukka Sanna-Kaisa, Sarajärvi Timo, Natunen Teemu, Kurkinen Kaisa M.A., Huovinen Jaakko, Mäkinen Petra, Laitinen Marjo, Koivisto Anne M., Mattila Kari M., Lehtimäki Terho, Remes Anne M., Leinonen Ville, Haapasalo Annakaisa, Soininen Hilkka, Hiltunen Mikko. 2015. Journal of Alzheimer's disease. 43: 565-573