Front page
People
Research groups
Projects
About

Suomi English

Front page
People
Research groups
Projects
About

Edit data
Logout

Refine your search

Frontpage
People
Merja Kokki

Merja Kokki

merjakok@student.uef.fi

Information Publications

Publications

53/53 items

Maternal and fetal buprenorphine pharmacokinetics in pregnant sheep during transdermal patch dosing: Buprenorphine pharmacokinetics in pregnant sheep
Hakomäki, Henriikka; Kokki, Hannu; Lehtonen, Marko; Räsänen, Juha; Voipio, Hanna-Marja; Ranta, Veli-Pekka; Kokki, Merja. 2021. European journal of pharmaceutical sciences. 165: 105936
Updated Clinical Pharmacokinetics and Pharmacodynamics of Oxycodone
Kinnunen, M; Piirainen, P; Kokki, H; Lammi, P; Kokki, M. 2019. Clinical pharmacokinetics. 58: 705-725
A prospective, randomized, open label, controlled study investigating the efficiency and safety of 3 different methods of rectus sheath block analgesia following midline laparotomy
Purdy, Martin; Kinnunen, Mari; Kokki, Merja; Anttila, Maarit; Eskelinen, Matti; Hautajärvi, Heidi; Lehtonen, Marko; Kokki, Hannu. 2018. Medicine. 97: e9968
Life satisfaction and pain interference in spine surgery patients before and after surgery: comparison between on-opioid and opioid-naïve patients
Kuronen, M; Kokki, H; Nyyssönen, T; Savolainen, S; Kokki, M. 2018. Quality of life research. 27: 3013-3020
Plasma Catalase in Relation to Pain Following Midline Laparotomy: A Prospective Study of Patients with Benign Diseases and Patients with Cancer
Saimanen, Iina; Kärkkäinen, Jari; Selander, Tuomas; Purdy, Martin; Kokki, Merja; Kokki, Hannu; Eskelinen Matti. 2018. Anticancer research. 38: 6479-6484
Procalcitonin: a feasible biomarker for severe bacterial infections in Obstetrics and Gynecology?
Tujula, Benita; Kokki, Hannu; Räsänen, Juha; Kokki, Merja. 2018. Acta obstetricia et gynecologica scandinavica. 97: 505-506
Response to 'The role of procalcitonin in the diagnosis and management of infections in the field of obstetrics and gynecology'
Tujula, Benita; Kokki, Hannu; Räsänen, Juha; Kokki, Merja. 2018. Acta obstetricia et gynecologica scandinavica. 97: 1407-1408
Ilokaasu, onko käyttöaiheita 2020-luvulla?
Kokki Merja, Tohmo Harri, Kokki Hannu. 2017. Finnanest. 50: 98-106
Maturation of Oxycodone Pharmacokinetics in Neonates and Infants: a Population Pharmacokinetic Model of Three Clinical Trials
Välitalo P, Kokki M, Ranta V-P, Olkkola KT, Hooker AC, Kokki H. 2017. Pharmaceutical research. 34: 1125-1133
Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach
Yamamoto Y, Välitalo PA, Wong YC, Huntjens DR, Proost JH, Vermeulen A, Krauwinkel W, Beukers MW, Kokki H, Kokki M, Danhof M, van Hasselt JGC, de Lange ECM. 2017. European journal of pharmaceutical sciences. 2018; 112: 168-179
Author's Reply to Parsons: "Cytotoxicity of Oxycodone and Morphine in Human Neuroblastoma and Mouse Motoneuronal Cells: A Comparative Approach"
Kokki Merja, Pasanen Markku, Kokki Hannu. 2016. Drugs in R and D. 16: 287-288
Central Nervous System Penetration of the Opioid Oxycodone
Kokki Hannu, Kokki Merja. Teoksessa: Victor R. Preedy(toim.) , 2016. Neuropathology of Drug Addictions and Substance Misuse. s. 457-466. Academic press
Cytotoxicity of Oxycodone and Morphine in Human Neuroblastoma and Mouse Motoneuronal Cells: A Comparative Approach
Kokki Merja, Pesonen Maija, Vehviläinen Piia, Litmala Outi, Pasanen Markku, Kokki Hannu. 2016. Drugs in R and D. 16: 155-163
Does Post-Surgery Placement of Rectus Sheath Block Analgesia Alter the Oxidative Stress Biomarker 8-OHdG Concentrations: A Randomised Trial of Patients with Cancer and Benign Disease
Purdy Martin, Kokki Merja, Anttila Maarit, Aspinen Samuli, Juvonen Petri, Selander Tuomas, Kokki Hannu, Pulkki Kari, Eskelinen Matti. 2016. Cancer genomics and proteomics. 13: 239-244
Does the Rectus Sheath Block Analgesia Reduce the Inflammatory Response Biomarkers' IL-1ra, IL-6, IL-8, IL-10 and IL-1ß Concentrations Following Surgery? : A Randomized Clinical Trial of Patients with Cancer and Benign Disease
Purdy Martin, Kokki Merja, Anttila Maarit, Aspinen Samuli, Juvonen Petri, Korhonen Riika, Selander Tuomas, Kokki Hannu, Eskelinen Matti. 2016. Anticancer research. 36: 3005-3011
Foetal Fentanyl Exposure and Ion Trapping after Intravenous and Transdermal Administration to the Ewe
Heikkinen Emma M, Kokki Hannu, Heikkinen Aki, Ranta Veli-Pekka, Räsänen Juha, Voipio Hanna-Marja, Kokki Merja. 2016. Basic and clinical pharmacology and toxicology. 2017; 120: 195-198
Levobupivacaine for Spinal Anesthesia in Children: Cerebrospinal Fluid Aspiration Before the Injection Does not Affect the Spread or Duration of the Sensory Block
Kokki Merja, Heikkinen Marja, Kumpulainen Elina, Vähäoja Aura, Kokki Hannu. 2016. Anesthesiology and pain medicine. 6: e33815
Maturation of oxycodone pharmacokinetics in neonates and infants: Oxycodone and its metabolites in plasma and urine
Kokki Merja, Heikkinen Marja, Välitalo Pyry, Hautajärvi Heidi, Hokkanen Juho, Pitkänen Hanna, Sankilampi Ulla, Ranta Veli-Pekka, Kokki Hannu. 2016. British journal of clinical pharmacology. 2017; 83: 791-800
Opioid-Induced Bowel Dysfunction in Patients Undergoing Spine Surgery: Comparison of Oxycodone and Oxycodone-Naloxone Treatment
Kokki Merja, Kuronen Moona, Naaranlahti Toivo, Nyyssönen Timo, Pikkarainen Ira, Savolainen Sakari, Kokki Hannu. 2016. Advances in therapy. [Epub ahead of print 05 Dec 2016]: 1-16
Sufentanil sublingual formulation for the treatment of acute, moderate to severe postoperative pain in adult patients
Porela-Tiihonen Susanna, Kokki Merja, Kokki Hannu. 2016. Expert review of neurotherapeutics. 2017; 17: 101-111
The cerebrospinal fluid distribution of postoperatively administred dexketoprofen and etoricoxib and their effect on pain and inflammatory markers in patients undergoing hip arthroplasty
Piirainen Annika, Kokki Merja, Hautajärvi Heidi, Lehtonen Marko, Miettinen Hannu, Pulkki Kari, Ranta Veli-Pekka, Kokki Hannu. 2016. Clinical drug investigation. 36: 545-555
A Dose-Finding Study of Dexketoprofen in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Clinical Trial on Effects on the Analgesic Concentration of Oxycodone
Piirainen Annika, Kokki Hannu, Immonen Satu, Eskelinen Matti, Häkkinen Merja R, Hautajärvi Heidi, Kokki Merja. 2015. Drugs in R and D. 15: 319-328
Fentanyl Pharmacokinetics in Pregnant Sheep after Intravenous and Transdermal Administration to the Ewe
Heikkinen Emma M, Voipio Hanna-Marja, Laaksonen Sakari, Haapala Linnea, Räsänen Juha, Acharya Ganesh, Erkinaro Tiina, Haapsamo Mervi, Hautajärvi Heidi, Kokki Hannu, Kokki Merja, Heikkinen Aki T. 2015. Basic and clinical pharmacology and toxicology. 117: 156-163
Health-related quality of life after caract surgery with the phacoemulsification technique and intraocular lens implantation
Porela-Tiihonen Susanna, Roine Risto P, Sintonen Harri, Kaarniranta Kai, Kokki Merja, Kokki Hannu. 2015. Acta ophthalmologica. 2016; 94: 21-25
Intravenous dexketoprofen induces less injection pain than racemic ketoprofen
Sjövall S, Kokki M, Nokela A, Halinen L, Turunen M, Kokki H. 2015. Journal of clinical pharmacy and therapeutics. 40: 431-435
Laparoscopic Surgery: A Narrative Review of Pharmacotherapy in Pain Management
Sjövall Sari, Kokki Merja, Kokki Hannu. 2015. Drugs. 75: 1867-1889
Neonatal safety of maternal fentanyl during labour
Kokki M, Westeren-Punnonen S, Hautajärvi H, Heinonen S, Mazzei M, Määttä S, Paalanen E, Kokki H. 2015. British journal of anaesthesia. 115: 636-638
Pharmacokinetics of intranasal fentanyl in parturient
Kokki Merja, Heikkinen Aki T, Raatikainen Kaisa, Ranta Veli-Pekka, Hautajärvi H, Kokki Hannu. 2015. British journal of anaesthesia. 115: 635-636
Postdural puncture headache and epidural blood patch use in elderly patients
Sjövall Sari, Kokki Merja, Turunen Eetu, Laisalmi Mirjam, Alahuhta Seppo, Kokki Hannu. 2015. Journal of clinical anesthesia. 27: 574-578
Pain relief after strabismus surgery in children: ketoprofen 'Pro Re Nata' or scheduled dosing?
Ihajoki Mirkka, Kokki Hannu, Purhonen Sinikka, Kokki Merja. 2014. Journal of anesthesia and clinical research. 5: 4 sivua
Population pharmacometrics in support of analgesics studies
Välitalo Pyry, Ranta Veli-Pekka, Hooker AC, Kokki Merja, Kokki Hannu. 2014. Acta anaesthesiologica scandinavica. 58: 143-156
Raskauden aikaisen lääketutkimuksen haasteita
Kokki Merja, Pasanen Markku, Heikkinen Aki T, Kokki Hannu. 2014. Finnanest. 47: 142-147
Central nervous system penetration of oxycodone after intravenous and epidural administration
Kokki Merja, Välitalo Pyry, Kuusisto M, Ranta Veli-Pekka, Raatikainen Kaisa, Hautajärvi H, Kokki Hannu. 2013. British journal of anaesthesia. 2014:112: 133-140
The influence of timing on the effectiveness of epidural blood patches in parturients
Kokki M, Sjövall S, Keinänen M, Kokki H. 2013. International journal of obstetric anesthesia. 22: 303-309
Absorption of different oral dosage forms of oxycodone in the elderly: a cross-over clinical trial in patients undergoing cystoscopy
Kokki M, Välitalo P, Rasanen I, Aaltomaa S, Ojanperä I, Eskelinen M, Kokki H. 2012. European journal of clinical pharmacology. 68: 1357-1363
Analgesic concentrations of oxycodone--a prospective clinical PK/PD study in patients with laparoscopic cholecystectomy
Kokki Merja, Broms Susanna, Eskelinen Matti, Rasanen Ilpo, Ojanperä Ilkka, Kokki Hannu. 2012. Basic and clinical pharmacology and toxicology. 110: 469-475
Epidural blood patches are effective for postdural puncture headache in pediatrics - a 10-year experience
Kokki M, Sjövall S, Kokki H, Bosenberg A. 2012. Pediatric anesthesia. 22: 1205-1210
Intravenous oxycodone for pain relief in the first stage of labour--maternal pharmacokinetics and neonatal exposure
Kokki M, Franco MG, Raatikainen K, Välitalo P, Sankilampi U, Heinonen S, Neuvonen PJ, Kokki H. 2012. Basic and clinical pharmacology and toxicology. 111: 182-188
Oxycodone for the treatment of postoperative pain
Kokki H, Kokki M, Sjövall S. 2012. Expert opinion on pharmacotherapy. 13: 1045-58
Plasma and cerebrospinal fluid pharmacokinetics of naproxen in children
Välitalo Pyry, Kumpulainen Elina, Manner Minna, Kokki Merja, Lehtonen Marko, Hooker Andrew C, Ranta Veli-Pekka, Kokki Hannu. 2012. Journal of clinical pharmacology. 52: 1516-1526
Populaatiofarmakokinetiikan perusteita anestesia- ja tehohoitolääkäreille
Ranta Veli-Pekka, Välitalo Pyry, Kokki Merja, Kokki Hannu. 2012. Finnanest. 45: 128-135
Prolonged-release Oxycodone/Naloxone in Postoperative Pain Management: from a Randomized Clinical Trial to Usual Clinical Practice
Kuusniemi K, Zöllner J, Sjövall S, Huhtala J, Karjalainen P, Kokki M, Lemken J, Oppermann J, Kokki H. 2012. Journal of international medical research. 40: 1775-1793
Suspected unexpected adverse effect of sugammadex: hypotension
Kokki M, Ali M, Turunen M, Kokki H. 2012. European journal of clinical pharmacology. 68: 899-900
The Analgesic Concentration of Oxycodone with Co-administration of Paracetamol - A Dose-Finding Study in Adult Patients Undergoing Laparoscopic Cholecystectomy
Kokki M, Broms S, Eskelinen M, Neuvonen PJ, Halonen T, Kokki H. 2012. Basic and clinical pharmacology and toxicology. 111: 391-395
Potentially detrimental effects of N-acetylcysteine on renal function in knee arthroplasty
Laisalmi-Kokki M, Pesonen E, Kokki H, Valta P, Pitkänen M, Teppo A-M, Honkanen E, Lindgren L. 2009. Free radical research. 43: 691-696
Diclofenac readily penetrates the cerebrospinal fluid in children
Kokki H, Kumpulainen E, Laisalmi M, Savolainen J, Rautio J, Lehtonen M. 2008. British journal of clinical pharmacology. 65: 879-884
How readily does ketorolac penetrate cerebrospinal fluid in children?
Kumpulainen E, Kokki H, Laisalmi M, Heikkinen M, Savolainen J, Rautio J, Lehtonen M. 2008. Journal of clinical pharmacology. 48: 495-501
Cerebrospinal fluid distribution of ibuprofen after intravenous administration in children
Kokki H, Kumpulainen E, Lehtonen M, Laisalmi M, Heikkinen M, Savolainen J, Rautio J. 2007. Pediatrics. 120: e1002-e1008
Plasma and cerebrospinal fluid concentrations of indomethacin in children after intravenous administration
Mannila A, Kumpulainen E, Lehtonen M, Heikkinen M, Laisalmi M, Salo T, Rautio J, Savolainen J, Kokki H. 2007. Journal of clinical pharmacology. 47: 94-100
Cerebrospinal fluid distribution of ketoprofen after intravenous administration in young children
Mannila A, Kokki H, Heikkinen M, Laisalmi M, Lehtonen M, Louhisto HL, Järvinen T, Savolainen J. 2006. Clinical pharmacokinetics. 45: 737-743
Interpleural bupivacaine and intravenous oxycodone for pain treatment after thoracotomy in children
Kokki H, Laisalmi M, Vanamo K. 2006. Journal of opioid management. 2: 290-294
High success rate and low incidence of headache and neurological symptoms with two spinal needle designs in children
Kokki H, Turunen M, Heikkinen M, Reinikainen M, Laisalmi M. 2005. Acta anaesthesiologica scandinavica. 49: 1367-1372
Isobaric ropivacaine 5 mg/mL for spinal anesthesia in children
Kokki H, Ylönen P, Laisalmi M, Heikkinen M, Reinikainen M. 2005. Anesthesia and analgesia. 100: 66-70

University of Eastern Finland Joensuu, Kuopio © University of Eastern Finland

Facebook Instagram Twitter YouTube LinkedIn Snapchat SoundCloud TikTok Vimeo

Accessibility statement
Cookie usage
Give feedback

Manage consent

We use cookies to optimize our website and our service.

Functional Functional Always active

The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.

Asetukset Asetukset

Tekninen tallennus tai pääsy on tarpeen laillisessa tarkoituksessa sellaisten asetusten tallentamiseen, joita tilaaja tai käyttäjä ei ole pyytänyt.

Statistics Statistics

The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you. Tekninen tallennus tai pääsy, jota käytetään yksinomaan anonyymeihin tilastollisiin tarkoituksiin. Ilman haastetta, Internet-palveluntarjoajasi vapaaehtoista suostumusta tai kolmannen osapuolen lisätietueita pelkästään tähän tarkoitukseen tallennettuja tai haettuja tietoja ei yleensä voida käyttää tunnistamaan sinua.

Marketing Marketing

The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.

Show preferences

{title} {title} {title}

Refine your search

Merja Kokki

Maternal and fetal buprenorphine pharmacokinetics in pregnant sheep during transdermal patch dosing: Buprenorphine pharmacokinetics in pregnant sheep

Updated Clinical Pharmacokinetics and Pharmacodynamics of Oxycodone

A prospective, randomized, open label, controlled study investigating the efficiency and safety of 3 different methods of rectus sheath block analgesia following midline laparotomy

Life satisfaction and pain interference in spine surgery patients before and after surgery: comparison between on-opioid and opioid-naïve patients

Plasma Catalase in Relation to Pain Following Midline Laparotomy: A Prospective Study of Patients with Benign Diseases and Patients with Cancer

Procalcitonin: a feasible biomarker for severe bacterial infections in Obstetrics and Gynecology?

Response to 'The role of procalcitonin in the diagnosis and management of infections in the field of obstetrics and gynecology'

Ilokaasu, onko käyttöaiheita 2020-luvulla?

Maturation of Oxycodone Pharmacokinetics in Neonates and Infants: a Population Pharmacokinetic Model of Three Clinical Trials

Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach

Author's Reply to Parsons: "Cytotoxicity of Oxycodone and Morphine in Human Neuroblastoma and Mouse Motoneuronal Cells: A Comparative Approach"

Central Nervous System Penetration of the Opioid Oxycodone

Cytotoxicity of Oxycodone and Morphine in Human Neuroblastoma and Mouse Motoneuronal Cells: A Comparative Approach

Does Post-Surgery Placement of Rectus Sheath Block Analgesia Alter the Oxidative Stress Biomarker 8-OHdG Concentrations: A Randomised Trial of Patients with Cancer and Benign Disease

Does the Rectus Sheath Block Analgesia Reduce the Inflammatory Response Biomarkers' IL-1ra, IL-6, IL-8, IL-10 and IL-1ß Concentrations Following Surgery? : A Randomized Clinical Trial of Patients with Cancer and Benign Disease

Foetal Fentanyl Exposure and Ion Trapping after Intravenous and Transdermal Administration to the Ewe

Levobupivacaine for Spinal Anesthesia in Children: Cerebrospinal Fluid Aspiration Before the Injection Does not Affect the Spread or Duration of the Sensory Block

Maturation of oxycodone pharmacokinetics in neonates and infants: Oxycodone and its metabolites in plasma and urine

Opioid-Induced Bowel Dysfunction in Patients Undergoing Spine Surgery: Comparison of Oxycodone and Oxycodone-Naloxone Treatment

Sufentanil sublingual formulation for the treatment of acute, moderate to severe postoperative pain in adult patients

The cerebrospinal fluid distribution of postoperatively administred dexketoprofen and etoricoxib and their effect on pain and inflammatory markers in patients undergoing hip arthroplasty

A Dose-Finding Study of Dexketoprofen in Patients Undergoing Laparoscopic Cholecystectomy: A Randomized Clinical Trial on Effects on the Analgesic Concentration of Oxycodone

Fentanyl Pharmacokinetics in Pregnant Sheep after Intravenous and Transdermal Administration to the Ewe

Health-related quality of life after caract surgery with the phacoemulsification technique and intraocular lens implantation

Intravenous dexketoprofen induces less injection pain than racemic ketoprofen

Laparoscopic Surgery: A Narrative Review of Pharmacotherapy in Pain Management

Neonatal safety of maternal fentanyl during labour

Pharmacokinetics of intranasal fentanyl in parturient

Postdural puncture headache and epidural blood patch use in elderly patients

Pain relief after strabismus surgery in children: ketoprofen 'Pro Re Nata' or scheduled dosing?

Population pharmacometrics in support of analgesics studies

Raskauden aikaisen lääketutkimuksen haasteita

Central nervous system penetration of oxycodone after intravenous and epidural administration

The influence of timing on the effectiveness of epidural blood patches in parturients

Absorption of different oral dosage forms of oxycodone in the elderly: a cross-over clinical trial in patients undergoing cystoscopy

Analgesic concentrations of oxycodone--a prospective clinical PK/PD study in patients with laparoscopic cholecystectomy

Epidural blood patches are effective for postdural puncture headache in pediatrics - a 10-year experience

Intravenous oxycodone for pain relief in the first stage of labour--maternal pharmacokinetics and neonatal exposure

Oxycodone for the treatment of postoperative pain

Plasma and cerebrospinal fluid pharmacokinetics of naproxen in children

Populaatiofarmakokinetiikan perusteita anestesia- ja tehohoitolääkäreille

Prolonged-release Oxycodone/Naloxone in Postoperative Pain Management: from a Randomized Clinical Trial to Usual Clinical Practice

Suspected unexpected adverse effect of sugammadex: hypotension

The Analgesic Concentration of Oxycodone with Co-administration of Paracetamol - A Dose-Finding Study in Adult Patients Undergoing Laparoscopic Cholecystectomy

Potentially detrimental effects of N-acetylcysteine on renal function in knee arthroplasty

Diclofenac readily penetrates the cerebrospinal fluid in children

How readily does ketorolac penetrate cerebrospinal fluid in children?

Cerebrospinal fluid distribution of ibuprofen after intravenous administration in children

Plasma and cerebrospinal fluid concentrations of indomethacin in children after intravenous administration

Cerebrospinal fluid distribution of ketoprofen after intravenous administration in young children

Interpleural bupivacaine and intravenous oxycodone for pain treatment after thoracotomy in children

High success rate and low incidence of headache and neurological symptoms with two spinal needle designs in children

Isobaric ropivacaine 5 mg/mL for spinal anesthesia in children