Rami Korhonen
Professor
Professor of Biomechanics
Head of the Biophysics of Bone and cartilage research group
Head of the Musculoskeletal Diseases research community
Department of Technical Physics, Faculty of Science, Forestry and Technology
rami.korhonen@uef.fi | +358 40 355 3260
2000: MSc in medical physics, University of Kuopio, Finland
2004: PhD in physics, University of Kuopio, Finland
2005-2007: Post doc, University of Calgary, Alberta, Canada
2008-2013: Academy Research Fellow, University of Eastern Finland
2013-2016. Associate Professor of biomechanics, University of Eastern Finland
2016-current: Professor of biomechanics
Dr. Korhonen has vast experience in musculoskeletal biomechanics, imaging and modelling at cellular, molecular, tissue and joint levels. Currently his research aims primarily at 1) revealing new biomechanically and biochemically driven mechanisms leading to osteoarthritis and 2) developing novel imaging and in silico modelling methods for osteoarthritis prognosis and treatment planning. Dr. Korhonen has published over 200 peer-reviewed articles and supervised 28 PhD theses, and his research has been funded by EU (e.g. ERC), Academy of Finland, Business Finland, and other national and international foundations and organizations.
Links to the BBC research group and MSKD research community:
https://sites.uef.fi/biophysics/
https://www.uef.fi/en/research-community/musculoskeletal-diseases-msd
Research groups
Publications
243/243 items-
Clinical Super-Resolution Computed Tomography of Bone Microstructure: Application in Musculoskeletal and Dental Imaging
Rytky, Santeri J O; Tiulpin, Aleksei; Finnilä, Mikko A J; Karhula, Sakari S; Sipola, Annina; Kurttila, Väinö; Valkealahti, Maarit; Lehenkari, Petri; Joukainen, Antti; Kröger, Heikki; Korhonen, Rami K; Saarakkala, Simo; Niinimäki, Jaakko. 2024. Annals of biomedical engineering. [Epub ahead of print 15 Feb 2024]: 1-15 -
Deep learning based detection of osteophytes in radiographs and magnetic resonance imagings of the knee using 2D and 3D morphology
Daneshmand, Mitra; Panfilov, Egor; Bayramoglu, Neslihan; Korhonen, Rami K; Saarakkala, Simo. 2024. Journal of orthopaedic research. [Epub ahead of print 7 Feb 2024]: 1-9 -
Independent and combined effects of obesity and traumatic joint injury to the structure and composition of rat knee cartilage
Karjalainen, Kalle; Tanska, Petri; Collins, Kelsey H; Herzog, Walter; Korhonen, Rami K; Moo, Eng Kuan. 2024. Connective tissue research. [Epub ahead of print 26 Mar 2024]: 1-16 -
Muscle Morphology Does Not Solely Determine Knee Flexion Weakness After Anterior Cruciate Ligament Reconstruction with a Semitendinosus Tendon Graft: A Combined Experimental and Computational Modeling Study
Kositsky, Adam; Stenroth, Lauri; Barrett, Rod S; Korhonen, Rami K; Vertullo, Christopher J; Diamond, Laura E.; Saxby, David J. 2024. Annals of biomedical engineering. [Epub ahead of print 29 Feb 2024]: 1-13 -
Sensitivity analysis of paediatric knee kinematics to the graft surgical parameters during anterior cruciate ligament reconstruction: A sequentially linked neuromusculoskeletal-finite element analysis
Dastgerdi, Ayda Karimi; Esrafilian, Amir; Carty, Christopher P; Nasseri, Azadeh; Barzan, Martina; Korhonen, Rami K; Astori, Ivan; Hall, Wayne; Saxby, David John. 2024. Computer methods and programs in biomedicine. 248: -
3-D T1 relaxation time measurements in an equine model of subtle post-traumatic osteoarthritis using MB-SWIFT
Pala, Swetha; Hänninen, Nina E; Mohammadi, Ali; Ebrahimi, Mohammadhossein; te Moller, Nikae CR; Brommer, Harold; René van Weeren, P; Mäkelä, Janne TA; Korhonen, Rami K; Afara, Isaac O; Töyräs, Juha; Mikkonen, Santtu; Nissi, Mikko J; Nykänen, Olli. 2023. Journal of orthopaedic research. 41: 2657-2666 -
Comparison of constitutive models for meniscus and their effect on the knee joint biomechanics during gait
Simkheada, Tulashi; Orozco, Gustavo A.; Korhonen, Rami K; Tanska, Petri; Mononen, Mika E. 2023. Computer methods in biomechanics and biomedical engineering. 26: 2008-2021 -
Contrast Agent Diffusion Reflects Biomechanical Finite Element Model Properties Of Articular Cartilage
Tuppurainen, J..; Jäntti, J.; Nissinen, M.T.; Fugazzola, M.C.; van Weeren, R.; Joenathan, A.; Grinstaff, M.W.; Matikka, H.; Korhonen, R.K.; Mäkelä, J.T.. 2023. Osteoarthritis and cartilage -
Contribution of collagen degradation and proteoglycan depletion to cartilage degeneration in primary and secondary osteoarthritis: an in silico study
Elahi, SA; Castro-Viñuelas, R; Tanska, P; Korhonen, RK; Lories, R; Famaey, N; Jonkers, I. 2023. Osteoarthritis and cartilage. 31: 741-752 -
Dependence of crack shape in loaded articular cartilage on the collagenous structure
Al-Saffar, Yasir; Moo, Eng Kuan; Pingguan-Murphy, Belinda; Matyas, John; Korhonen, Rami K.; Herzog, Walter. 2023. Connective tissue research. 64: 294-306 -
Effects of gait modifications on tissue‐level knee mechanics in individuals with medial tibiofemoral osteoarthritis: A proof‐of‐concept study towards personalized interventions
Esrafilian, Amir; Halonen, Kimmo S; Dzialo, Christine. M; Mannisi, Marco; Mononen, Mika E; Tanska, Petri; Woodburn, Jim; Korhonen, Rami K; Andersen, Michael S. 2023. Journal of orthopaedic research. 2024; 42: 326-338 -
Injury-related cell death and proteoglycan loss in articular cartilage: Numerical model combining necrosis, reactive oxygen species, and inflammatory cytokines
Kosonen, Joonas P.; Eskelinen, Atte S. A; Orozco, Gustavo A.; Nieminen, Petteri; Anderson, Donald D; Grodzinsky, Alan J; Korhonen, Rami K; Tanska, Petri. 2023. PLoS computational biology. 19: -
Knee cartilage mechanics in finite element analysis using inputs from different musculoskeletal software
Joose Peitola; Amir Esrafilian; Atte Eskelinen; Michael Skipper Andersen; Rami Korhonen. 2023. -
Load-induced fluid pressurisation in hydrogel systems before and after reinforcement by melt-electrowritten fibrous meshes
Moo, Eng Kuan; Ebrahimi, Mohammadhossein; Hrynevich, Andrei; de Ruijter, Mylène; Castilho, Miguel; Malda, Jos; Korhonen, Rami K. 2023. Journal of the mechanical behavior of biomedical materials. 143: . 105941 -
Micro-computed Tomography-Based Collagen Orientation and Anisotropy Analysis of Rabbit Articular Cartilage
Ojanen, Simo P; Finnilä, Mikko AJ; Herzog, Walter; Saarakkala, Simo; Korhonen, Rami K; Rieppo, Lassi. 2023. Annals of biomedical engineering. 51: 1769-1780 -
Microscale investigation of the anisotropic swelling of cartilage tissue and cells in response to hypo-osmotic challenges
Moo, Eng Kuan; Sibole, Scott C; Federico, Salvatore; Korhonen, Rami K; Herzog, Walter. 2023. Journal of orthopaedic research. 2024; 42: 54-65 -
Morphology of proximal and distal human semitendinosus compartments and the effects of distal tendon harvesting for anterior cruciate ligament reconstruction
Kositsky, Adam; Maas, Huub; Barrett, Rod S; Kennedy, Ben; Stenroth, Lauri; Korhonen, Rami K; Vertullo, Chris J; Diamond, Laura E; Saxby, David J. 2023. Journal of anatomy. 243: 297-310 -
Multiscale In Silico Modeling of Cartilage Injuries
Korhonen, Rami K; Eskelinen, Atte SA; Orozco, Gustavo A; Esrafilian, Amir; Florea, Cristina; Tanska, Petri. Teoksessa: Connizzo, BK; Han, L; Sah, RL(toim.) , 2023. Electromechanobiology of Cartilage and Osteoarthritis : A Tribute to Alan Grodzinsky on his 75th Birthday. s. 45-56. Springer -
Near-infrared spectroscopic assessment of patellar tendon mechanics
Kositsky, Adam; Torniainen, Jari; Stenroth, Lauri; Nippolainen, Ervin; Mäkelä, Janne T.A.; Paakkari, Petri; Kröger, Heikki; Töyräs, Juha; Korhonen, Rami K.; Afara, Isaac O.. 2023. -
Obesity with ACL transection leads to severe collagen matrix disorganization of knee cartilage in a rat model
Karjalainen, Kalle; Tanska, Petri; Collins, Kelsey; Herzog, Walter; Korhonen, Rami; Moo, Eng Kuan. 2023. Transactions of the annual meeting of the Orthopaedic Research Society -
Patellar tendon and tibial cartilage viscoelastic properties are inversely related in osteoarthritic knees
Kositsky, Adam; Linus, Awuniji; Stenroth, Lauri; Mononen, Mika E.; Nippolainen, Ervin; Kröger, Heikki; Töyräs, Juha; Mäkelä, Janne T.A.; Tanska, Petri; Afara, Isaac O.; Korhonen, Rami K.. 2023. Transactions of the annual meeting of the Orthopaedic Research Society -
Prediction of Knee Joint Compartmental Loading Maxima Utilizing Simple Subject Characteristics and Neural Networks
Lavikainen, Jere; Stenroth, Lauri; Alkjær, Tine; Karjalainen, Pasi A; Korhonen, Rami K.; Mononen, Mika E. 2023. Annals of biomedical engineering. 51: 2479-2489 -
Sensitivity of simulated knee joint mechanics to selected human and bovine fibril-reinforced poroelastic material properties
Jahangir, Sana; Esrafilian, Amir; Ebrahimi, Mohammadhossein; Stenroth, Lauri; Alkjær, Tine; Henriksen, Marius; Englund, Martin; Mononen, Mika E; Korhonen, Rami K; Tanska, Petri. 2023. Journal of biomechanics. 160: -
Signatures of disease progression in knee osteoarthritis: insights from an integrated multi-scale modeling approach, a proof of concept
Mohout, Ikram; Elahi, Seyed Ali; Esrafilian, Amir; Killen, Bryce A; Korhonen, Rami K; Verschueren, Sabine; Jonkers, Ilse. 2023. Frontiers in bioengineering and biotechnology. 11: . 1214693 -
Towards a Transferable Modeling Method of the Knee to Distinguish Between Future Healthy Joints from Osteoarthritic Joints: Data from the Osteoarthritis Initiative
Paz, Alexander; García, José J; Korhonen, Rami K; Mononen, Mika E. 2023. Annals of biomedical engineering. 51: 2192-2203 -
Triple contrast computed tomography reveals site‐specific biomechanical differences in human knee joint – a proof of concept study
Orava, Heta; Paakkari, Petri; Jäntti, Jiri; Honkanen, Miitu KM; Honkanen, Juuso TJ; Virén, Tuomas; Joenathan, Anisha; Tanska, Petri; Korhonen, Rami K; Grinstaff, Mark W; Töyräs, Juha; Mäkelä, Janne TA. 2023. Journal of orthopaedic research. 2024; 42: 415-424 -
Validation and evaluation of subject-specific finite element models of the pediatric knee
Karimi Dastgerdi, Ayda; Esrafilian, Amir; Carty, Christopher P; Nasseri, Azadeh; Yahyaiee Bavil, Alireza; Barzan, Martina; Korhonen, Rami K; Astori, Ivan; Hall, Wayne; Saxby, David John. 2023. Scientific reports. 13: . 18328 -
Visible and Near-Infrared Spectroscopy Enables Differentiation of Normal and Early Osteoarthritic Human Knee Joint Articular Cartilage
Linus, Awuniji; Tanska, Petri; Sarin, Jaakko K.; Nippolainen, Ervin; Tiitu, Virpi; Mäkelä, Janne T.A.; Töyräs, Juha; Korhonen, Rami K.; Mononen, Mika E.; Afara, Isaac O.. 2023. Annals of biomedical engineering. 51: 2245-2257 -
A musculoskeletal finite element model of rat knee joint for evaluating cartilage biomechanics during gait
Orozco, Gustavo A.; Karjalainen, Kalle; Moo, Eng Kuan; Stenroth, Lauri; Tanska, Petri; Rios, Jaqueline Lourdes; Tuomainen, Teemu V.; Nissi, Mikko J.; Isaksson, Hanna; Herzog, Walter; Korhonen, Rami K.. 2022. PLoS computational biology. 18: -
A novel knee joint model in FEBio with inhomogeneous fibril-reinforced biphasic cartilage simulating tissue mechanical responses during gait: data from the osteoarthritis initiative
Paz, Alexander; Orozco, Gustavo A; Tanska, Petri; García, José J; Korhonen, Rami K. Mononen, Mika E. 2022. Computer methods in biomechanics and biomedical engineering. [Published online: 05 Sep 2022]: 1-15 -
Adaptation of Fibril-Reinforced Poroviscoelastic Properties in Rabbit Collateral Ligaments 8 Weeks After Anterior Cruciate Ligament Transection
Orozco, Gustavo A; Ristaniemi, Aapo; Haghighatnejad, Mehrnoush; Mohammadi, Ali; Finnilä, Mikko AJ; Saarakkala, Simo; Herzog, Walter; Isaksson, Hanna; Korhonen, Rami K. 2022. Annals of biomedical engineering. [Published: 21 September 2022]: 1-15 -
Alterations in the Functional Knee Alignment Are Not an Effective Strategy to Modify the Mediolateral Distribution of Knee Forces During Closed Kinetic Chain Exercises
Bosch, Will; Esrafilian, Amir; Vartiainen, Paavo; Arokoski, Jari; Korhonen, Rami K.; Stenroth, Lauri. 2022. Journal of applied biomechanics. 38: 424-433 -
An EMG-Assisted Muscle-Force Driven Finite Element Analysis Pipeline to Investigate Joint- and Tissue-Level Mechanical Responses in Functional Activities: Towards a Rapid Assessment Toolbox
Esrafilian, Amir; Stenroth, Lauri; Mononen, Mika E.; Vartiainen, Paavo; Tanska, Petri; Karjalainen, Pasi A.; Suomalainen, Juha-Sampo; Arokoski, J.; Saxby, David J.; Lloyd, David G.; Korhonen, Rami K.. 2022. IEEE transactions on biomedical engineering. 69: 2860-2871 -
Assessment of Ligament Viscoelastic Properties Using Raman Spectroscopy
Cui, Andy; Nippolainen, Ervin; Shaikh, Rubina; Torniainen, Jari; Ristaniemi, Aapo; Finnilä, Mikko; Korhonen, Rami K.; Saarakkala, Simo; Herzog, Walter; Töyräs, Juha; Afara, Isaac O.. 2022. Annals of biomedical engineering. 50: 1134-1142 -
Associations of human femoral condyle cartilage structure and composition with viscoelastic and constituent-specific material properties at different stages of osteoarthritis
Ebrahimi, Mohammadhossein; Turkiewicz, Aleksandra; Finnilä, Mikko A.J.; Saarakkala, Simo; Englund, Martin; Korhonen, Rami K.; Tanska, Petri. 2022. Journal of biomechanics. 145: -
Changes in subchondral bone structure and mechanical properties do not substantially affect cartilage mechanical responses – A finite element study
Orava, Heta; Huang, Lingwei; Ojanen, Simo P; Mäkelä, Janne TA; Finnilä, Mikko AJ; Saarakkala, Simo; Herzog, Walter; Korhonen, Rami K; Töyräs, Juha; Tanska, Petri. 2022. Journal of the mechanical behavior of biomedical materials. 128: -
Correction to: Rapid X-Ray-Based 3-D Finite Element Modeling of Medial Knee Joint Cartilage Biomechanics During Walking
Jahangir, Sana; Mohammadi, Ali; Mononen, Mika E.; Hirvasniemi, Jukka; Suomalainen, Juha-Sampo; Saarakkala, Simo; Korhonen, Rami K.; Tanska, Petri. 2022. Annals of biomedical engineering. 50: 614-614 -
Crack propagation in articular cartilage under cyclic loading using cohesive finite element modeling
Orozco, Gustavo A; Tanska, Petri; Gustafsson, Anna; Korhonen, Rami K; Isaksson, Hanna. 2022. Journal of the mechanical behavior of biomedical materials. 131: -
Cyclic loading regime considered beneficial does not protect injured and interleukin-1-inflamed cartilage from post-traumatic osteoarthritis
Eskelinen, Atte SA; Florea, Cristina; Tanska, Petri; Hung, Han-Hwa K.; Frank, Eliot H.; Mikkonen, Santtu; Nieminen, Petteri; Julkunen, Petro; Grodzinsky, Alan J.; Korhonen, Rami K.. 2022. Journal of biomechanics. 141: -
Differential Site-specific Proteoglycan Loss Occurs With Anterior Cruciate Ligament Transection In Obese Rats
Karjalainen, Kalle; Tanska, Petri; Collins, Kelsey; Herzog, Walter; Korhonen, Rami K; Moo, Eng Kuan . 2022. Transactions of the annual meeting of the Orthopaedic Research Society -
Dual‐contrast micro‐CT enables cartilage lesion detection and tissue condition evaluation ex vivo
Honkanen, Miitu KM; Mohammadi, Ali; te Moller, Nikae CR; Ebrahimi, Mohammadhossein; Xu, Wujun; Plomp, Saskia; Pouran, Behdad; Lehto, Vesa‐Pekka; Brommer, Harold; van Weeren, P René; Korhonen, Rami K; Töyräs, Juha; Mäkelä, Janne TA. 2022. Equine veterinary journal. 2023; 55: 315-324 -
Effect of cells on spatial quantification of proteoglycans in articular cartilage of small animals
Karjalainen, Kalle; Tanska, Petri; Sibole, Scott C; Mikkonen, Santtu; Herzog, Walter; Korhonen, Rami; Moo, Eng Kuan. 2022. Connective tissue research. 63: 603-614 -
Effect of osteoporosis-related reduction in the mechanical properties of bone on the acetabular fracture during a sideways fall: A parametric finite element approach
Khakpour, Shahab; Esrafilian, Amir; Tanska, Petri; Mononen, Mika E.; Korhonen, Rami K.; Jämsä, Timo. 2022. PLoS ONE. 17: -
Elastic and viscoelastic human patellar tendon regional properties
Kositsky, Adam; Stenroth, Lauri; Nippolainen, Ervin; Mäkelä, Janne; Paakkari, Petri; Torniainen, Jari; Kröger, Heikki; Afara, Isaac; Korhonen, Rami. 2022. -
In vivo assessment of the passive stretching response of the bicompartmental human semitendinosus muscle using shear-wave elastography
Kositsky, Adam; Saxby, David J; Lesch, Kim J; Barrett, Rod S; Kröger, Heikki; Lahtinen, Olli; Diamond, Laura E; Korhonen, Rami K; Stenroth, Lauri. 2022. Journal of applied physiology. 132: 438-447 -
Near infrared spectroscopic evaluation of biochemical and crimp properties of knee joint ligaments and patellar tendon
Torniainen, Jari; Ristaniemi, Aapo; Sarin, Jaakko K; Prakash, Mithilesh; Afara, Isaac O; Finnilä, Mikko AJ; Stenroth, Lauri; Korhonen, Rami K; Töyräs, Juha. 2022. PLoS ONE. 17: -
On the morphology of the semitendinosus muscle in legs with and without distal tendon harvesting
Kositsky, Adam; Maas, Huub; Barrett, Rod; Kennedy, Ben; Stenroth, Lauri; Korhonen, Rami K; Vertullo, Chris J; Diamond, Laura E; Saxby, David J. 2022. Journal of anatomy -
Rapid X-Ray-Based 3-D Finite Element Modeling of Medial Knee Joint Cartilage Biomechanics During Walking
Jahangir, Sana; Mohammadi, Ali; Mononen, Mika E.; Hirvasniemi, Jukka; Suomalainen, Juha-Sampo; Saarakkala, Simo; Korhonen, Rami K.; Tanska, Petri. 2022. Annals of biomedical engineering. 50: 666-679 -
Reduction of pro-inflammatory cytokine activity results in proteoglycan content recovery in a computational model of injured articular cartilage implementing cytokines and reactive oxygen species
Kosonen, Joonas; Eskelinen, Atte; Orozco, Gustavo; Anderson, Donald; Grodzinsky, Alan; Tanska, Petri; Korhonen, Rami. 2022. Orthopaedic Research Society -
Site- and Zone-Dependent Changes in Proteoglycan Content and Biomechanical Properties of Bluntly and Sharply Grooved Equine Articular Cartilage
Mohammadi, Ali; te Moller, Nikae C. R.; Ebrahimi, Mohammadhossein; Plomp, Saskia; Brommer, Harold; van Weeren, P. René; Mäkelä, Janne T. A.; Töyräs, Juha; Korhonen, Rami K.. 2022. Annals of biomedical engineering. 50: 1787–1797 -
Synovial fluid interleukin-1α cannot fully explain proteoglycan degradation in rats
Karjalainen, Kalle; Tanska, Petri; Collins, Kelsey; Herzog, Walter; Korhonen, Rami; Moo, Eng Kuan. 2022. Osteoarthritis and cartilage -
The intrinsic quality of proteoglycans, but not collagen fibres, degrades in osteoarthritic cartilage
Moo, Eng Kuan; Ebrahimi, Mohammadhossein; Sibole, Scott C; Tanska, Petri; Korhonen, Rami K. 2022. Acta biomaterialia. 153: 178-189 -
Viscoelastic properties of six regions of the human patellar tendon
Kositsky, Adam; Stenroth, Lauri; Nippolainen, Ervin; Mäkelä, Janne T.A; Paakkari, Petri; Torniainen, Jari; Kröger, Heikki; Afara, Isaac O; Korhonen, Rami K. 2022. Transactions of the annual meeting of the Orthopaedic Research Society -
A mechanobiological model combining inflammation and biomechanical stimulus to predict cell death and subsequent proteoglycan loss in articular cartilage after traumatic injury
Kosonen JP, Eskelinen ASA, Orozco GA, Nieminen P, Grodzinsky AJ, Korhonen RK, Tanska P. 2021. -
A numerical framework for mechano-regulated tendon healing-Simulation of early regeneration of the Achilles tendon
Notermans, Thomas; Tanska, Petri; Korhonen, Rami K.; Khayyeri, Hanifeh; Isaksson, Hanna. 2021. PLoS computational biology. 17: 1008636 -
An in silico Framework of Cartilage Degeneration That Integrates Fibril Reorientation and Degradation Along With Altered Hydration and Fixed Charge Density Loss
Elahi, Seyed Ali; Tanska, Petri; Korhonen, Rami K.; Lories, Rik; Famaey, Nele; Jonkers, Ilse. 2021. Frontiers in bioengineering and biotechnology. 9: 680257 -
Automated analysis of rabbit knee calcified cartilage morphology using micro-computed tomography and deep learning
Rytky, Santeri JO; Huang, Lingwei; Tanska, Petri; Tiulpin, Aleksei; Panfilov, Egor; Herzog, Walter; Korhonen, Rami K; Saarakkala, Simo; Finnilä, Mikko AJ. 2021. Journal of anatomy. 239: 251-263 -
Biomechanical, biochemical, and near infrared spectral data of bovine knee ligaments and patellar tendon
Ristaniemi, Aapo; Torniainen, Jari; Paakkonen, Tommi; Stenroth, Lauri; Finnilä, Mikko A.J.; Tanska, Petri; Töyräs, Juha; Korhonen, Rami K.. 2021. Data in brief. 36: 106976 -
Cartilage lesions and interleukin-1-driven inflammation abrogate the beneficial effects of moderate dynamic loading in a bovine cartilage model of post-traumatic osteoarthritis
Eskelinen ASA, Florea C, Mikkonen S, Nieminen P, Julkunen P, Tanska P, Grodzinsky AJ, Korhonen RK. 2021. -
Collagen fibres determine the crack morphology in articular cartilage
Moo, Eng Kuan; Tanska, Petri; Federico, Salvatore; Al-Saffar, Yasir; Herzog, Walter; Korhonen, Rami K. 2021. Acta biomaterialia. 126: 301-314 -
Deformation behaviors and mechanical impairments of tissue cracks in immature and mature cartilages
Moo, Eng Kuan; Al-Saffar, Yasir; Le, Tina; Seerattan, Ruth A; Pingguan-Murphy, Belinda; Korhonen, Rami K; Herzog, Walter. 2021. Journal of orthopaedic research. [ePub ahead of print 27 Dec 2021]: 1-10 -
Early changes in osteochondral tissues in a rabbit model of post-traumatic osteoarthritis
Huang, Lingwei; Riihioja, Ilari; Tanska, Petri; Ojanen, Simo; Palosaari, Sanna; Kröger, Heikki; Saarakkala, Simo J; Herzog, Walter; Korhonen, Rami K; Finnilä, Mikko A J. 2021. Journal of orthopaedic research. 39: 2556-2567 -
Effect of Impact Velocity, Flooring Material, and Trochanteric Soft-Tissue Quality on Acetabular Fracture during a Sideways Fall: A Parametric Finite Element Approach
Khakpour, Shahab; Tanska, Petri; Esrafilian, Amir; Mononen, Mika E; Saarakkala, Simo; Korhonen, Rami K; Jämsä, Timo. 2021. Applied sciences. 11: 365 -
Elastic, Dynamic Viscoelastic and Model-Derived Fibril-Reinforced Poroelastic Mechanical Properties of Normal and Osteoarthritic Human Femoral Condyle Cartilage
Ebrahimi, M; Finnilä, MAJ; Turkiewicz, A; Englund, M; Saarakkala, S; Korhonen, RK; Tanska, P. 2021. Annals of biomedical engineering. 49: 2622-2634 -
Expediting Finite Element Analyses for Subject-Specific Studies of Knee Osteoarthritis: A Literature Review
Paz, Alexander; Orozco, Gustavo; Korhonen, Rami; García, José Jaime; Mononen, Mika. 2021. Applied sciences. 11: 24 -
Functional and Structural Properties of Human Patellar Articular Cartilage in Osteoarthritis
Nissinen, Mikko T; Hänninen, Nina; Prakash, Mithilesh; Mäkelä, Janne TA; Nissi, Mikko J; Töyräs, Juha; Nieminen, Miika T. Korhonen, Rami K; Tanska, Petri. 2021. Journal of biomechanics. 126: 110634 -
Guide to mechanical characterization of articular cartilage and hydrogel constructs based on a systematic in silico parameter sensitivity analysis
Elahi, Seyed Ali; Tanska, Petri; Mukherjee, Satanik; Korhonen, Rami K.; Geris, Liesbet; Jonkers, Ilse; Famaey, Nele. 2021. Journal of the mechanical behavior of biomedical materials. 124: 104795 -
High-resolution infrared microspectroscopic characterization of cartilage cell microenvironment
Linus, A; Ebrahimi, M; Turunen, MJ; Saarakkala, S; Joukainen, A; Kröger, H; Koistinen, A; Finnilä, M; Afara, IO; Mononen, ME; Tanska, P; Korhonen, RK. 2021. Acta biomaterialia. 134: 252-260 -
Machine learning augmented near-infrared spectroscopy: In vivo follow-up of cartilage defects
Sarin, Jaakko K; Te Moller, Nikae Cr; Mohammadi, Ali; Prakash, Mithilesh; Torniainen, Jari; Brommer, Harold; Nippolainen, Ervin; Shaikh, Rubina; Mäkelä, Janne Ta; Korhonen, Rami K; René van Weeren, P; Afara, Isaac O; Töyräs, Juha. 2021. Osteoarthritis and cartilage. 29: 423-432 -
Regional in vitro human patellar tendon tensile mechanical properties and in situ near infrared spectroscopy prediction
Kositsky, Adam; Torniainen, Jari; Stenroth, Lauri; Nippolainen, Ervin; Mäkelä, Janne; Paakkari, Petri; Kröger, Heikki; Afara, Isaac; Korhonen, Rami. 2021. -
Shear strain and inflammation-induced fixed charge density loss in the knee joint cartilage following ACL injury and reconstruction: A computational study
Orozco, Gustavo A; Eskelinen, Atte SA; Kosonen, Joonas P; Tanaka, Matthew S; Yang, Mingrui; Link, Thomas M; Ma, Benjamin; Li, Xiaojuan; Grodzinsky, Alan J; Korhonen, Rami K; Tanska, Petri. 2021. Journal of orthopaedic research. [Epub ahead of print 17 Sept 2021]: 1-18 -
Structure, composition and fibril-reinforced poroviscoelastic properties of bovine knee ligaments and patellar tendon
Ristaniemi, Aapo; Regmi, Dristi; Mondal, Diponkor; Torniainen, Jari; Tanska, Petri; Stenroth, Lauri; Finnilä, Mikko AJ; Töyräs, Juha; Korhonen, Rami K. 2021. Journal of the royal society interface. 18: 20200737 -
Subject-specific biomechanical analysis to estimate locations susceptible to osteoarthritis - Finite element modeling and MRI follow-up of ACL reconstructed patients
Bolcos, Paul O; Mononen, Mika E; Roach, Koren E; Tanaka, Matthew S; Suomalainen, Juha-Sampo; Mikkonen, Santtu; Nissi, Mikko J; Töyräs, Juha; Link, Thomas M; Souza, Richard B; Majumdar, Sharmila; Ma, C Benjamin; Li, Xiaojuan; Korhonen, Rami K. 2021. Journal of orthopaedic research. [ePub ahead of print 24 Nov 2021]: 1-12 -
The effect of subchondral bone plate thickness and trabecular bone volume fraction on the mechanical behavior of cartilage in post-traumatic osteoarthritis
Orava, H; Tanska, P; Huang, L; Ojanen, SP; Mäkelä, JTA; Finnilä, MAJ; Saarakkala, S; Herzog, W; Korhonen, RK; Töyräs, J. 2021. Transactions of the annual meeting of the Orthopaedic Research Society -
The mechanical arrangement of the human semitendinosus muscle as assessed with shear wave elastography
Kositsky, Adam; Saxby, David; Lesch, Kim; Barrett, Rod; Kröger, Heikki; Lahtinen, Olli; Diamond, Laura; Korhonen, Rami; Stenroth, Lauri. 2021. -
A multiscale framework for evaluating three-dimensional cell mechanics in fibril-reinforced poroelastic tissues with natomical cell distribution - Analysis of chondrocyte deformation behavior in mechanically loaded articular cartilage
Tanska, P; Venäläinen, MS; Erdemir, A; Korhonen, RK. 2020. Journal of biomechanics. 101: 109648 -
Clinical Contrast-enhanced Computed Tomography with Semiautomatic Segmentation Provides Feasible Input for Computational Models of the Knee Joint
Myller, KAH; Korhonen, R; Töyräs, J; Tanska, P; Väänänen, S; Jurvelin, JS; Saarakkala, S; Mononen, ME. 2020. Journal of biomechanical engineering: transactions of the ASME. 142: 51001 -
Comparison of material models for anterior cruciate ligament in tension: from poroelastic to a novel fibril-reinforced nonlinear composite model
Ristaniemi, A; Tanska, P; Stenroth, L; Finnilä, MAJ; Korhonen, RK. 2020. Journal of biomechanics. 114: 110141 -
Comparison of water, hydroxyproline, uronic acid and elastin contents of bovine knee ligaments and patellar tendon and their relationships with biomechanical properties
Ristaniemi, A; Torniainen, J; Stenroth, L; Finnilä, MAJ; Paakkonen, T; Töyräs, J; Korhonen, RK. 2020. Journal of the mechanical behavior of biomedical materials. 104: 103639 -
Discrete element and finite element methods provide similar estimations for hip joint contact mechanics during walking gait
Li, Mao; Venäläinen, Mikko S; Chandra, Shekhar S; Patel, Rushabh; Fripp, Jurgen; Engstrom, Craig; Korhonen, Rami K; Töyräs, Juha; Crozier, Stuart. 2020. Journal of biomechanics. 115: 110163 -
EMG-Assisted Muscle Force Driven Finite Element Model of the Knee Joint with Fibril-Reinforced Poroelastic Cartilages and Menisci
Esrafilian, A; Stenroth, L; Mononen, ME; Tanska, P; Avela, J; Korhonen, RK. 2020. Scientific reports. 10: 3026 -
Identification of locations susceptible to osteoarthritis in patients with anterior cruciate ligament reconstruction: Combining knee joint computational modelling with follow-up T1p and T2 imaging
Bolcos, PO; Mononen, ME; Tanaka, MS; Yang, M; Suomalainen, JS; Nissi, MJ; Töyräs, J; Ma, B; Li, X; Korhonen, RK. 2020. Clinical biomechanics. 79: 104844 -
Machine Learning Classification of Articular Cartilage Integrity Using Near Infrared Spectroscopy
Afara, Isaac O; Sarin, Jaakko K; Ojanen, Simo; Finnilä, Mikko A J; Herzog, Walter; Saarakkala, Simo; Korhonen Rami K; Töyräs, Juha. 2020. Cellular and molecular bioengineering. 13: 219-228 -
Machine learning methods to support personalized neuromusculoskeletal modelling
Saxby, David J; Killen, Bryce Adrian; Pizzolato, C; Carty, CP; Diamond, LE; Modenese, L; Fernandez, J; Davico, G; Barzan, M; Lenton, G; da Luz, S Brito; Suwarganda, E; Devaprakash, D; Korhonen, RK; Alderson, JA; Besier, TF; Barrett, RS; Lloyd, DG. 2020. Biomechanics and modeling in mechanobiology. 19: 1169-1185 -
Mechanobiological Model for Simulation of Injured Cartilage Degradation via Pro-Inflammatory Cytokines and Mechanical Stimulus
Eskelinen, ASA; Tanska, P; Florea, C; Orozco, GA; Julkunen, P; Grodzinsky, AJ; Korhonen, RK. 2020. PLoS computational biology. 16: 1007998 -
Mechanobiological model combining inflammation and abnormal mechanical loading predicts local cartilage degeneration around lesion
Kosonen JP, Eskelinen ASA, Orozco GA, Tanska P, Yang M, Tanaka MS, Ma B, Li X, Grodzinsky AJ, Korhonen RK. 2020. -
Multiparametric MR Imaging Reveals Early Cartilage Degeneration at 2 and 8 Weeks After ACL Transection in a Rabbit Model
Kajabi, Abdul Wahed; Casula, Victor; Ojanen, Simo; Finnilä, Mikko A; Herzog, Walter; Saarakkala, Simo; Korhonen, Rami K; Nissi, Mikko J; Nieminen, Miika T. 2020. Journal of orthopaedic research. 38: 1974-1986 -
Prediction of Local Fixed Charge Density Loss in Cartilage Following ACL Injury and Reconstruction: A Computational Proof-Of-Concept Study With MRI Follow-Up
Orozco, GA; Bolcos, P; Mohammadi, A; Tanaka, MS; Yang, M; Link, TM; Ma, B; Li, X; Tanska, P; Korhonen, RK. 2020. Journal of orthopaedic research. 2021; 39: 1064-1081 -
Raman microspectroscopic analysis of the tissue-specific composition of the human osteochondral junction in osteoarthritis: a pilot study
Gupta, Shuvashis Das; Finnilä, Mikko; Karhula, Sakari; Kauppinen, Sami; Joukainen, Antti; Kröger, Heikki; Korhonen, Rami; Thambyah, Ashvin; Rieppo, Lassi; Saarakkala, Simo. 2020. Acta biomaterialia. 106: 145-155 -
Rapid CT-based Estimation of Articular Cartilage Biomechanics in the Knee Joint Without Cartilage Segmentation
Mohammadi, Ali; Myller, Katariina A H; Tanska, Petri; Hirvasniemi, Jukka; Saarakkala, Simo; Töyräs, Juha; Korhonen, Rami K; Mononen, Mika E. 2020. Annals of biomedical engineering. 48: 2965-2975 -
Structural, compositional, and functional effects of blunt and sharp cartilage damage on the joint: a 9-month equine groove model study
Te Moller, Nikae CR; Mohammadi, Ali; Plomp, Saskia; Serra Bragança, Filipe M; Beukers, Martijn; Pouran, Behdad; Afara, Isaac O; Nippolainen, Ervin; Mäkelä, Janne TA; Korhonen, Rami K; Töyräs, Juha; Brommer, Harold; René van Weeren, P. 2020. Journal of orthopaedic research. 2021; 39: 2363-2375 -
Structure-Function Relationships of Healthy and Osteoarthritic Human Tibial Cartilage: Experimental and Numerical Investigation
Ebrahimi, Mohammadhossein; Turunen, Mikael J; Finnilä, Mikko A; Joukainen, Antti; Kröger, Heikki; Saarakkala, Simo; Korhonen, Rami K; Tanska, Petri. 2020. Annals of biomedical engineering. 48: 2887-2900 -
Anterior cruciate ligament transection alters the n-3/n-6 fatty acid balance in the lapine infrapatellar fat pad
Mustonen, AM; Käkelä, R; Finnilä, MAJ; Sawatsky, A; Korhonen, RK; Saarakkala, S; Herzog, W; Paakkonen, T; Nieminen, P. 2019. Lipids in health and disease. 18: 67 -
Anterior cruciate ligament transection of rabbits alters composition, structure and biomechanics of articular cartilage and chondrocyte deformation 2 weeks post-surgery in a site-specific manner
Ojanen, Simo Pekka; Finnilä, Mikko Arttu Jalmari; Mäkelä, Janne; Saarela, Kiira; Happonen, Emilia; Herzog, Walter; Saarakkala, Simo; Korhonen, Rami Kristian. 2019. Journal of biomechanics. 2020; 98: 109450 -
Combining mechanical stimulus and cytokine-mediated degradation mechanisms in injured cartilage
Eskelinen ASA, Orozco GA, Tanska P, Grodzinsky AJ, Korhonen RK. 2019. -
Computational evaluation of altered biomechanics related to articular cartilage lesions observed in vivo
Myller, KAH; Korhonen, RK; Töyräs, J; Salo, J; Jurvelin, JS; Venäläinen, MS. 2019. Journal of orthopaedic research. 37: 1042-1051 -
Eight-year trajectories of changes in health-related quality of life in knee osteoarthritis: Data from the Osteoarthritis Initiative (OAI).
Törmälehto, S; Aarnio, E; Mononen, ME; Arokoski, JPA; Korhonen, RK; Martikainen, JA. 2019. PLoS ONE. 14: e0219902 -
Elastic, Viscoelastic and Fibril-Reinforced Poroelastic Material Properties of Healthy and Osteoarthritic Human Tibial Cartilage
Ebrahimi, M; Ojanen, S; Mohammadi, A; Finnilä, MA; Joukainen, A; Kröger, H; Saarakkala, S; Korhonen, RK; Tanska, P. 2019. Annals of biomedical engineering. 47: 953-966 -
Experimental mechanical strain measurement of tissues
Huang, L; Korhonen, RK; Turunen, MJ; Finnilä, MAJ. 2019. PeerJ. 7: e6545 -
Maximum shear strain-based algorithm can predict proteoglycan loss in damaged articular cartilage
Eskelinen, ASA; Mononen, ME; Venäläinen, MS; Korhonen, RK; Tanska, P. 2019. Biomechanics and modeling in mechanobiology. 18: 753-778 -
Quantifying Subresolution 3D Morphology of Bone with Clinical Computed Tomography
Karhula, SS; Finnilä, MAJ4; Rytky, SJO; Cooper, DM; Thevenot, J; Valkealahti, M; Pritzker, KPH; Haapea, M; Joukainen, A; Lehenkari, P; Kröger, H; Korhonen, RK; Nieminen, HJ; Saarakkala, S. 2019. Annals of biomedical engineering. 2020; 48: 595-605 -
A novel mechanobiological model can predict how physiologically relevant dynamic loading causes proteoglycan loss in mechanically injured articular cartilage
Orozco, Gustavo A; Tanska, Petri; Florea, Cristina; Grodzinsky, Alan J; Korhonen, Rami K. 2018. Scientific reports. 8: 15599 -
Characterizing human subchondral bone properties using near-infrared (NIR) spectroscopy
Afara, IO; Florea, C; Olumegbon, IA; Eneh, CT; Malo, MKH; Korhonen, RK; Töyräs, J. 2018. Scientific reports. 8: 9733 -
Comparison between kinetic and kinetic-kinematic driven knee joint finite element models
Bolcos, PO; Mononen, ME; Mohammadi, A; Ebrahimi, M; Tanaka, MS; Samaan, MA; Souza, RB; Li, X; Suomalainen, JS; Jurvelin, JS; Töyräs, J; Korhonen, RK. 2018. Scientific reports. 8: 17351 -
Comparison of elastic, viscoelastic and failure tensile material properties of knee ligaments and patellar tendon
Ristaniemi, Aapo; Stenroth, Lauri; Mikkonen, Santtu; Korhonen, Rami K. 2018. Journal of biomechanics. 79: 31-38 -
Effect of centrifugal force on the development of articular neocartilage with bovine primary chondrocytes
Prittinen, J; Ylärinne, J; Piltti, J; Karhula, SS; Rieppo, L; Ojanen, SP; Korhonen, RK; Saarakkala, S; Lammi, MJ; Qu, C. 2018. Cell and tissue research. 2019; 375: 629-639 -
Evaluation of the effect of bariatric surgery-induced weight loss on knee gait and cartilage degeneration
Liukkonen, MK; Mononen, ME; Vartiainen, P; Kaukinen, P; Bragge, T; Suomalainen, JS; Malo, MKH; Venesmaa, S; Käkelä, P; Pihlajamäki, J; Karjalainen, PA; Arokoski, JP; Korhonen, R. 2018. Journal of biomechanical engineering: transactions of the ASME. 14: 41008 -
Functional Effects of an Interpenetrating Polymer Network on Articular Cartilage Mechanical Properties
Mäkelä, JT; Cooper, BG; Korhonen, RK; Grinstaff, MW; Snyder, BD. 2018. Osteoarthritis and cartilage. 26: 414-421 -
Health-related quality of life in relation to symptomatic and radiographic definitions of knee osteoarthritis: data from Osteoarthritis Initiative (OAI) 4-year follow-up study
Törmälehto, Soili; Mononen, Mika E; Aarnio, Emma; Arokoski, Jari P A; Korhonen, Rami K; Martikainen, Janne. 2018. Health and quality of life outcomes. 16: 154 -
Interrelationship of cartilage composition and chondrocyte mechanics after a partial meniscectomy in the rabbit knee joint - Experimental and numerical analysis
Ronkainen, AP; Tanska, P; Fick, JM; Herzog, W; Korhonen, RK. 2018. Journal of biomechanics. 2019; 86: 65-75 -
Iterative and discrete reconstruction in the evaluation of the rabbit model of osteoarthritis
Ketola, Juuso H; Karhula, Sakari S; Finnilä, Mikko AJ; Korhonen, Rami K; Herzog, Walter; Siltanen, Samuli; Nieminen, Miika T; Saarakkala, Simo. 2018. Scientific reports. 8: 12051 -
Mechanisms to reveal how normal dynamic loading causes proteoglycan loss in mechanically injured cartilage: A mechanobiological model combined with experimental findings
Orozco GA, Tanska P, Eskelinen ASA, Florea C, Grodzinsky AJ, Korhonen RK. 2018. -
Near Infrared Spectroscopic Evaluation of Ligament and Tendon Biomechanical Properties
Torniainen, Jari; Ristaniemi, Aapo; Sarin, Jaakko K; Mikkonen, Santtu; Afara, Isaac O; Stenroth, Lauri; Korhonen, Rami K; Töyräs, Juha. 2018. Annals of biomedical engineering. 2019; 47: 213-222 -
Poisson's ratio of bovine meniscus determined combining unconfined and confined compression
Danso, EK; Julkunen, P; Korhonen, RK. 2018. Journal of biomechanics. 77: 233-237 -
Site-specific glycosaminoglycan content is better maintained in the pericellular matrix than the extracellular matrix in early post-traumatic osteoarthritis
Ojanen, SP; Finnilä, MAJ; Reunamo, AE; Ronkainen, AP; Mikkonen, S; Herzog, W; Saarakkala, S; Korhonen, RK. 2018. PLoS ONE. 13: e0196203 -
The effect of constitutive representations and structural constituents of ligaments on knee joint mechanics
Orozco, Gustavo A; Tanska, Petri; Mononen, Mika E; Halonen, Kimmo S; Korhonen, Rami K. 2018. Scientific reports. 8: 2323 -
The effect of different preconditioning protocols on repeatability of bovine ACL stress-relaxation response in tension
Ebrahimi, Mohammadhossein; Mohammadi, Ali; Ristaniemi, Aapo; Stenroth, Lauri; Korhonen, Rami K. 2018. Journal of the mechanical behavior of biomedical materials. 90: 493-501 -
Utilizing Atlas-Based Modeling to Predict Knee Joint Cartilage Degeneration: Data from the Osteoarthritis Initiative
Mononen, Mika E; Liukkonen, Mimmi K; Korhonen, Rami K. 2018. Annals of biomedical engineering. 2019; 47: 813-825 -
A computational algorithm to simulate disorganization of collagen network in injured articular cartilage
Tanska, Petri; Julkunen, Petro; Korhonen, Rami K. 2017. Biomechanics and modeling in mechanobiology. 2018; 17: 689-699 -
Alterations in structural macromolecules and chondrocyte deformations in lapine retropatellar cartilage 9 weeks after anterior cruciate ligament transection
Han SK, Ronkainen AP, Saarakkala S, Rieppo L, Herzog W, Korhonen RK. 2017. Journal of orthopaedic research. 2018; 36: 342-350 -
Application of a semi-automatic cartilage segmentation method for biomechanical modeling of the knee joint
Liukkonen Mimmi K, Mononen Mika E, Tanska Petri, Saarakkala Simo, Nieminen Miika T, Korhonen Rami K. 2017. Computer methods in biomechanics and biomedical engineering. Published online 12 Sep 2017]: 1-11 -
Estimation of the Effect of Body Weight on the Development of Osteoarthritis Based on Cumulative Stresses in Cartilage: Data from the Osteoarthritis Initiative
Klets O, Mononen ME, Liukkonen MK, Nevalainen MT, Nieminen MT, Saarakkala S, Korhonen RK. 2017. Annals of biomedical engineering. 2018; 46: 334-344 -
New Algorithm for Simulation of Proteoglycan Loss and Collagen Degeneration in the Knee Joint: Data from the Osteoarthritis Initiative
Mononen, Mika; Tanska, Petri; Isaksson, Hanna; Korhonen, Rami. 2017. Journal of orthopaedic research. 2018; 36: 1673-1683 -
Optical spectroscopic characterization of human meniscus biomechanical properties
Ala-Myllymäki Juho, Danso Elvis K, Honkanen Juuso TJ, Korhonen Rami K, Töyräs J, Afara Isaac O. 2017. Journal of biomedical optics. 22: 125008 (10 pages) -
Shear strain can trigger proteoglycan loss in injured cartilage
Eskelinen ASA, Tanska P, Mononen ME, Venäläinen M, Korhonen RK. 2017. -
Simulation of Subject-Specific Progression of Knee Osteoarthritis and Comparison to Experimental Follow-up Data: Data from the Osteoarthritis Initiative
Liukkonen MK, Mononen ME, Klets O, Arokoski JP, Saarakkala S, Korhonen RK. 2017. Scientific reports. 7: 9177 -
The effect of fixed charge density and cartilage swelling on mechanics of knee joint cartilage during simulated gait
Räsänen LP, Tanska P, Zbýn ¦, van Donkelaar CC, Trattnig S, Nieminen MT, Korhonen RK. 2017. Journal of biomechanics. 61: 34-44 -
Tissue viscoelasticity is related to tissue composition but may not fully predict the apparent-level viscoelasticity in human trabecular bone - An experimental and finite element study
Ojanen X, Tanska P, Malo MKH, Isaksson H, Väänänen SP, Koistinen AP, Grassi L, Magnusson SP, Ribel-Madsen SM, Korhonen RK, Jurvelin JS, Töyräs J. 2017. Journal of biomechanics. 65: 96-105 -
Ultrasound Assessment of Human Meniscus
Viren T, Honkanen JT, Danso EK, Rieppo L, Korhonen RK, Töyräs J. 2017. Ultrasound in medicine and biology. 43: 1753-1763 -
A Novel Method to Simulate the Progression of Collagen Degeneration of Cartilage in the Knee: Data from the Osteoarthritis Initiative
Mononen Mika E, Tanska Petri, Isaksson Hanna, Korhonen Rami K. 2016. Scientific reports. 6: 21415 -
A combined experimental atomic force microscopy-based nanoindentation and computational modeling approach to unravel the key contributors to the time-dependent mechanical behavior of single cells
Florea C, Tanska P, Mononen ME, Qu C, Lammi MJ, Laasanen MS, Korhonen RK. 2016. Biomechanics and modeling in mechanobiology. 2017; 16: 297-311 -
Comparison of different material models of articular cartilage in 3D computational modeling of the knee: data from the Osteoarthritis Initiative (OAI)
Klets O, Mononen ME, Tanska P, Nieminen MT, Korhonen RK, Saarakkala S. 2016. Journal of biomechanics. 49: 3891-3900 -
Early in situ changes in chondrocyte biomechanical responses due to a partial meniscectomy in the lateral compartment of the mature rabbit knee joint
Fick JM, Ronkainen AP, Madden R, Sawatsky A, Tiitu V, Herzog W, Korhonen RK. 2016. Journal of biomechanics. 49: 4057-4064 -
Effect of bone inhomogeneity on tibiofemoral contact mechanics during physiological loading
Venäläinen MS, Mononen ME, Väänänen SP, Jurvelin JS, Töyräs J, Virén T, Korhonen RK. 2016. Journal of biomechanics. 7: 1111-1120 -
Highly nonlinear stress-relaxation response of articular cartilage in indentation: Importance of collagen nonlinearity
Mäkelä JT, Korhonen RK. 2016. Journal of biomechanics. 49: 1734-1741 -
Importance of patella, quadriceps forces, and depthwise cartilage structure on knee joint motion and cartilage response during gait
Halonen KS, Mononen ME, Jurvelin JS, Töyräs J, Klodowski A, Kulmala JP, Korhonen RK. 2016. Journal of biomechanical engineering: transactions of the ASME. 138: BIO-15-1348, 11 pages -
Optical coherence tomography enables accurate measurement of equine cartilage thickness for determination of speed of sound
Puhakka PH, te Moller NCR, Tanska P, Saarakkala S, Tiitu V, Korhonen RK, Brommer H, Virén T, Jurvelin JS, Töyräs J. 2016. Acta orthopaedica. 87: 418-424 -
Optimal graft stiffness and pre-strain restore normal joint motion and cartilage responses in ACL reconstructed knee
Halonen KS, Mononen ME, Töyräs J, Kröger H, Joukainen A, Korhonen RK. 2016. Journal of biomechanics. 49: 2566-2576 -
Quantitative Evaluation of the Mechanical Risks Caused by Focal Cartilage Defects in the Knee
Venäläinen Mikko S, Mononen Mika E, Salo Jari, Räsänen Lasse P, Jurvelin Jukka S, Töyräs Juha, Virén Tuomas, Korhonen Rami K. 2016. Scientific reports. 6: 37538 -
Site-specific cell-tissue interactions in rabbit knee joint articular cartilage
Ronkainen AP, Fick JM, Herzog W, Korhonen RK. 2016. Journal of biomechanics. 49: 2882-2890 -
Spatial variation of fixed charge density in knee joint cartilage from sodium MRI - Implication on knee joint mechanics under static loading
Räsänen LP, Tanska P, Mononen ME, Lammentausta E, Zbýn ¦, Venäläinen MS, Szomolanyi P, van Donkelaar CC, Jurvelin JS, Trattnig S, Nieminen MT, Korhonen RK. 2016. Journal of biomechanics. 49: 3387-3396 -
Structure-function relationships of human meniscus
Danso EK, Oinas JM, Saarakkala S, Mikkonen S, Töyräs J, Korhonen RK. 2016. Journal of the mechanical behavior of biomedical materials. 67: 51-60 -
A multi-scale finite element model for investigation of chondrocyte mechanics in normal and medial meniscectomy human knee joint during walking
Tanska Petri, Mononen Mika E, Korhonen Rami K. 2015. Journal of biomechanics. 48: 1397-1406 -
Characterization of site-specific biomechanical properties of human meniscus-Importance of collagen and fluid on mechanical nonlinearities
Danso EK, Mäkelä JTA, Tanska P, Mononen ME, Honkanen JTJ, Jurvelin JS, Töyräs J, Julkunen P, Korhonen RK. 2015. Journal of biomechanics. 48: 1499-1507 -
Comparison of subchondral bone density and structure of tibia measured from plain radiograph with micro-computed tomography
Hirvasniemi J., Kokkonen H. T., Thevenot J., Finnilä M., Venäläinen M. S., Jämsä T., Korhonen R. K., Töyräs J., Saarakkala S.. 2015. Osteoarthritis and cartilage -
Contrast Enhanced Imaging of Human Meniscus Using Cone Beam CT
Honkanen JTJ, Danso EK, Suomalainen JS, Tiitu V, Korhonen RK, Jurvelin JS, Töyräs J. 2015. Osteoarthritis and cartilage. 23: 1367-1376 -
Correlation of Subchondral Bone Density and Structure from Plain Radiographs with Micro Computed Tomography Ex Vivo
Hirvasniemi Jukka, Thevenot Jérôme, Kokkonen Harri T, Finnilä Mikko A, Venäläinen Mikko S, Jämsä Timo, Korhonen Rami K, Töyräs Juha, Saarakkala Simo. 2015. Annals of biomedical engineering. 44: 1698 -
Merge of motion analysis, multibody dynamics and finite element method for the subject-specific analysis of cartilage loading patterns during gait: differences between rotation and moment-driven models of human knee joint
Klodowski Adam, Mononen Mika E, Kulmala Juha P, Valkeapää Antti, Korhonen Rami K, Avela Janne, Kiviranta Ilkka, Jurvelin Jukka S, Mikkola Aki. 2015. Multibody system dynamics. [epub ahead of print 29 July 2015]: 1-20 -
Modeling of interstitial fluid movement in soft tissue under negative pressure - relevance to treatment of tissue swelling
Iivarinen Jarkko T, Korhonen Rami K, Jurvelin Jukka S. 2015. Computer methods in biomechanics and biomedical engineering. [epub ahead of print 24 Oct 2015]: - -
New Concept to Restore Normal Cell Responses in Osteoarthritic Knee Joint Cartilage
Korhonen Rami K, Tanska Petri, Kaartinen Siru M, Fick James M, Mononen Mika E. 2015. Exercise and sport sciences reviews. 43: 143-152 -
Site-dependent biomechanical responses of chondrocytes in the rabbit knee joint
Fick JM, Ronkainen A, Herzog W, Korhonen RK. 2015. Journal of biomechanics. 48: 4010-4019 -
Three dimensional patient-specific collagen architecture modulates cartilage responses in the knee joint during gait
Räsänen LP, Mononen ME, Lammentausta E, Nieminen MT, Jurvelin JS, Korhonen RK. 2015. Computer methods in biomechanics and biomedical engineering. [epub ahead of print 30 Dec 2015]: -
Topographical investigation of changes in depth-wise proteoglycan distribution in rabbit femoral articular cartilage at 4 weeks after transection of the anterior cruciate ligament
Arokoski Mikko EA, Tiitu Virpi, Jurvelin Jukka S, Korhonen Rami K, Fick James M. 2015. Journal of orthopaedic research. 33: 1278-1286 -
Very early osteoarthritis changes sensitively fluid flow properties of articular cartilage
Mäkelä JTA, Han S-K, Herzog W, Korhonen RK. 2015. Journal of biomechanics. -: - -
Adiabatic rotating frame relaxation of MRI reveals early cartilage degeneration in a rabbit model of anterior cruciate ligament transection
Rautiainen Jari, Nissi Mikko J, Liimatainen Timo, Herzog Walter, Korhonen Rami K, Nieminen Miika T. 2014. Osteoarthritis and cartilage. 22: 1444-1452 -
Alterations in subchondral bone plate, trabecular bone and articular cartilage properties of rabbit femoral condyles at 4 weeks after anterior cruciate ligament transection
Florea Cristina, Malo Markus KH, Rautiainen Jari, Mäkelä Janne TA, Fick James M, Nieminen Miika T, Jurvelin Jukka S, Davidescu Arjana, Korhonen Rami K. 2014. Osteoarthritis and cartilage. [Epub ahead of print]: [Epub ahead of print] -
Automated determination of zone thicknesses of articular cartilage based on chondrocyte shapes
Turunen MJ, Jurvelin JS, Korhonen RK. 2014. WCB Transactions -
Back-side wear in HexLoc cups clinico-radiological, immunohistopathological, finite element and retrieval analysis studies
Kawaji H, Koistinen AP, Korhonen RK, Lappalainen R, Lohman M, Soininen A, Gomez-Barrena E, Konttinen YT, Ylinen P, Talloroth K. 2014. Journal of long-term effects of medical implants. 24: 319-331 -
Cell-tissue interactions in osteoarthritic human hip joint articular cartilage
Huttu Mari RJ, Puhakka Jani, Mäkelä Janne TA, Takakubo Yuya, Tiitu Virpi, Saarakkala Simo, Konttinen Yrjö T, Kiviranta Ilkka, Korhonen Rami K. 2014. Connective tissue research. 55: 282-91 -
Collagen content is increased in lapine femoral condyle cartilage four weeks after anterior cruciate ligament transection
Makela JTA, Herzog W, Korhonen RK. 2014. Orthopaedic Research Society -
Deformation of articular cartilage during static loading of a knee joint - Experimental and finite element analysis
Halonen KS, Mononen ME, Jurvelin JS, Töyräs J, Salo J, Korhonen RK. 2014. Journal of biomechanics. 47: 2467-2474 -
Determination of mechanical properties of chondrocytes in articular cartilage using atomic force microscopy
Florea C, Jakorinne A, Lammi M, Davidescu A, Korhonen RK. 2014. Solid state phenomena. 216: 134-139 -
Experimental and numerical analysis of soft tissue stiffness measurement using manual indentation device--significance of indentation geometry and soft tissue thickness
Iivarinen JT, Korhonen RK, Jurvelin JS. 2014. Skin research and technology. 20: 347-354 -
Importance of Material Properties and Porosity of Bone on Mechanical Response of Articular Cartilage in Human Knee Joint - A Two-Dimensional Finite Element Study
Venäläinen Mikko S, Mononen Mika E, Jurvelin Jukka S, Töyräs Juha, Virén Tuomas, Korhonen Rami K. 2014. Journal of biomechanical engineering: transactions of the ASME. 136: 121005 -
In vitro glycation of articular cartilage alters the biomechanical response of chondrocytes in a depth-dependent manner
Fick JM, Huttu MRJ, Lammi MJ, Korhonen RK. 2014. Osteoarthritis and cartilage. 22: 1410-1418 -
Site-dependent changes in structure and function of lapine articular cartilage 4 weeks after anterior cruciate ligament transection.
Mäkelä JTA, Rezaeian ZS, Mikkonen S, Madden R, Han S-K, Jurvelin JS, Herzog W, Korhonen RK.. 2014. Osteoarthritis and cartilage. 22: 869-878 -
A review of the combination of experimental measurements and fibril-reinforced modeling for investigation of articular cartilage and chondrocyte response to loading
Julkunen P, Wilson W, Isaksson H, Jurvelin JS, Herzog W and Korhonen RK. 2013. Computational and mathematical methods in medicine. 2013: 326150 -
Alternative Methods for Transforming T2 Anisotropy of MRI Into Collagen Architecture of Articular Cartilage - The Effect on Knee Joint Mechanics - Data From the Osteoarthritis Initiative (OAI)
Räsänen LP, Mononen ME, Nieminen MT, Lammentausta E, Jurvelin JS and Korhonen RK. 2013. -
Comparison of nonlinear mechanical properties of bovine articular cartilage and meniscus
Danso Elvis K, Honkanen Juuso TJ, Saarakkala Simo, Korhonen Rami K. 2013. Journal of biomechanics. [Epub ahead of print]: x-x -
Computational Models of Articular Cartilage
Korhonen RK, Julkunen P, Li LP, van Donkelaar CC. 2013. Computational and mathematical methods in medicine. 2013: 254507 -
Diffusion of ionic and non-ionic contrast agents in articular cartilage with increased cross-linking-contribution of steric and electrostatic effects
Kulmala KAM, Karjalainen HM, Kokkonen HT, Tiitu V, Kovanen V, Lammi MJ, Jurvelin JS, Korhonen RK, Töyräs J. 2013. Medical engineering and physics. 35: 1415-1420 -
Effect of Latewood Proportion on Mechanical Properties of Finnish Pine Wood Modified with Compression Drying
Mikkola Mika T, Korhonen Rami K. 2013. Wood and fiber science. 45: 335-342 -
Effect of latewood proportion on Finnish pine wood modified with compression drying
Mikkola MT, Korhonen RK. 2013. Wood and fiber science. 45: 335-342 -
Effects of radial tears and partial meniscectomy of lateral meniscus on the knee joint mechanics during the stance phase of the gait cycle - A 3D finite element study
Mononen ME, Jurvelin JS, Korhonen RK. 2013. Journal of orthopaedic research. 31: 1208-1217 -
Implementation of a gait cycle loading into healthy and meniscectomised knee joint models with fibril-reinforced articular cartilage
Mononen ME, Jurvelin JS, Korhonen RK. 2013. Computer methods in biomechanics and biomedical engineering. 2015; 18: 141-152 -
Importance of Patient-Specific Collagen Architecture on Knee Joint Stresses and Strains During Walk
Räsänen LP, Mononen ME, Jurvelin JS and Korhonen RK. 2013. -
Importance of depth-wise distribution of collagen and proteoglycans in articular cartilage - A 3D finite element study of stresses and strains in human knee joint
Halonen KS, Mononen ME, Jurvelin JS, Töyräs J, Korhonen RK. 2013. Journal of biomechanics. 46: 1184-1192 -
Site-Dependent Changes in Collagen Orientation and Elastic Moduli in Lapine Articular Cartilage at 4 Weeks After Anterior Cruciate Ligament Transection
Mäkelä JTA, Rezaeian ZS, Mikkonen S, Madden R, Han S-K, Jurvelin JS, Herzog W, Korhonen RK. 2013. -
Superficial Collagen Fibril Modulus and Pericellular Fixed Charge Density Modulate Chondrocyte Volumetric Behaviour in Early Osteoarthritis
Petri Tanska, Siru M. Turunen, Sang Kuy Han, Petro Julkunen, Walter Herzog, Rami K. Korhonen. 2013. Computational and mathematical methods in medicine. Volume 2013: 01-14 -
Tensile strains may be more important than compressive strains to modulate proteoglycan synthesis in dynamically loaded articular cartilage
Tanska, PK; Julkunen, P; Lammi, MJ; Korhonen, RK. 2013. -
A finite element study of micropipette aspiration of single cells: effect of compressibility
Jafari Bidhendi A, Korhonen RK. 2012. Computational and mathematical methods in medicine. Volume 2012: 9 -
Cell deformation behavior in a rabbit model of early OA
Turunen SM, Han S-K, Herzog W, Korhonen RK. 2012. -
Cell deformation behavior in mechanically loaded rabbit articular cartilage 4 weeks after anterior cruciate ligament transection
Turunen SM, Han SK, Herzog W, Korhonen RK.. 2012. Osteoarthritis and cartilage. -: - -
Changes in collagen orientation and proteoglycan content four weeks after anterior cruciate ligament transection modulate cell morphology in mechanically loaded rabbit cartilage
Turunen Siru M, Han Sang Kuy, Herzog Walter, Korhonen Rami K. 2012. -
Contrast-Enhanced Micro-Computed Tomography in Evaluation of Spontaneous Repair of Equine Cartilage
K.A.M. Kulmala, H.J. Pulkkinen, L. Rieppo, V. Tiitu, I. Kiviranta, A. Brünott, H. Brommer, R. van Weeren, P.A.J. Brama, M.T. Mikkola, R.K. Korhonen, J.S. Jurvelin, J.Töyräs. 2012. Cartilage. 3: 235-244 -
Effect of Lateral Meniscus Tears and Partial Meniscectomy on Stress Concentrations in Knee Joint During Walking
Mononen, M E; Jurvelin, J S; Korhonen, R K. Teoksessa: Smith & Nephew, Inc.(toim.) , 2012. Transactions of the Orthopaedic Research Society. s. 1881. -
Effect of superficial collagen patterns and fibrillation of femoral articular cartilage on knee joint mechanics-A 3D finite element analysis.
Mononen ME, Mikkola MT, Julkunen P, Ojala R, Nieminen MT, Jurvelin JS, Korhonen RK. 2012. Journal of biomechanics. 45: 579-87 -
Effects of Medium and Temperature on Cellular Responses in the Superficial Zone of Hypo-Osmotically Challenged Articular Cartilage
Huttu Mari, Turunen Siru, Sokolinski Viktoria, Tiitu Virpi, Lammi Mikko, Korhonen Rami K. 2012. Journal of functional biomaterials. 3: 544-555 -
Experimental and computational analysis of soft tissue mechanical response under negative pressure in forearm.
Iivarinen JT, Korhonen RK, Julkunen P, Jurvelin JS.. 2012. Skin research and technology. [Epub ahead of print]: - -
Implementation of Subject-Specific Collagen Architecture of Cartilage Into a 2D Computational Model of a Knee Joint - Data from the Osteoarthritis Initiative (OAI)
Räsänen LP, Mononen ME, Nieminen MT, Lammentausta E, Jurvelin JS, Korhonen RK. 2012. Journal of orthopaedic research. 31: 10-22 -
Implementation of a Gait Cycle in a 3D Fibril Reinforced Finite Element Model of a Knee Joint
Mononen, M E; Jurvelin, J S; Korhonen, R K. 2012. -
Relationships between cell volume, structure, composition and mechanical properties of osteoarthritic human hip articular cartilage
Huttu Mari, Puhakka Jani, Mäkelä Janne, Takakubo Yuya, Tiitu Virpi, Saarakkala Simo, Konttinen Yrjö, Kiviranta Ilkka, Korhonen Rami K. Teoksessa: ORS(toim.) , 2012. Transactions of the Orthopaedic Research Society. s. 1823. -
Structure-function relationships in osteoarthritic human articular cartilage
Makela JTA, Huttu MRJ, Korhonen R. Teoksessa: Smith & Nephew, Inc.(toim.) , 2012. Transactions of the Orthopaedic Research Society. s. 1800. -
Structure-function relationships in osteoarthritic human hip joint articular cartilage
Mäkelä JTA, Huttu MR, Korhonen RK.. 2012. Osteoarthritis and cartilage. 20: 1268-1277 -
The effect of collagen degradation on chondrocyte volume and morphology in bovine articular cartilage following a hypotonic challenge
Turunen SM, Lammi MJ, Saarakkala S, Han S-K, Herzog W, Tanska P, Korhonen RK. 2012. Biomechanics and modeling in mechanobiology. 2012: - -
A finite element study of micropipette aspiration of single cells: effect of compressibility
Jafari Bidhendi A, Korhonen RK. Teoksessa: Van Sint Jan S, Feipel V, Aerenhouts D, Baeyens J-P, Carpentier A, Cattrysse E, Clarys J-P, Duchateau J, Guissard N, Leloup T, Provyn S, Rooze M, Scafoglieri A, Schuind F, Van Roy P, Warzée N(toim.) , 2011. ISB2011 Brussels Conference book Program & Abstracts. s. International Society of Biomechanics. -
Alterations in structure and properties of collagen network of osteoarthritic and repaired cartilage modify knee joint stresses
Mononen ME, Julkunen P, Toyras J, Jurvelin JS, Kiviranta I, Korhonen RK. 2011. Biomechanics and modeling in mechanobiology. 10: 357-369 -
Biomechanics and modeling of skeletal soft tissues
Rami K. Korhonen, Simo Saarakkala. 2011. . . Intech media -
Can Collagen Fibrillation or Proteoglycan Depletion of Cartilage Explain Changed Deformation Behavior of Chondrocytes 9 Weeks after Anterior Cruciate Ligament Transaction?
Mäkitalo J, Saarakkala S, Rieppo L, Han S-K, Herzog W, Korhonen RK. 2011. Transactions of the annual meeting of the Orthopaedic Research Society -
Chondrocyte Volume and Morphology Following Mechanical Loading of Articular Cartilage are Altered Four Weeks After Anterior Cruciate Ligament Transaction in Rabbits
Turunen SM, Han S-K, Herzog W, Korhonen RK. 2011. -
Collagen Fibrils of Articular Cartilage Modulate Cell Deformations in Early Osteoarthritis
Tanska P, Julkunen P, Korhonen RK. 2011. -
Computed tomography detects changes in contrast agent diffusion after collagen cross-linking typical to natural aging of articular cartilage
Kokkonen HT, Mäkelä J, Kulmala KAM, Rieppo L, Jurvelin JS, Tiitu V, Karjalainen HM, Korhonen RK, Kovanen V, Töyräs J. 2011. Osteoarthritis and cartilage. 19: 1190-1198 -
Contrast enhanced computed tomography in evaluation of spontaneous cartilage repair
Kulmala K.A.M, Pulkkinen H.J, Rieppo L, Tiitu V, Kiviranta I, Brünott A, Brommer H, van Weeren R, Brama P.A.J, Mikkola M.T, Korhonen R.K, Jurvelin J.S, Töyräs J.. 2011. -
Early bone growth on the surface of titanium implants in rat femur is enhanced by an amorphous diamond coating
Jaatinen JJ, Korhonen RK, Pelttari A, Helminen HJ, Korhonen H, Lappalainen R, Kröger H. 2011. Acta orthopaedica. 82: 499-503 -
Effects of medium and temperature on cell mechanics in osmotically challenged articular cartilage
Huttu MRJ, Turunen SM, Sokolinski V, Tiitu V, Lammi MJ, Korhonen RK. 2011. -
Experimental and computational analysis of soft tissue stiffness in forearm using a manual indentation device
Iivarinen JT, Korhonen RK, Julkunen P, Jurvelin JS.. 2011. Medical engineering and physics. 33: 1245-53 -
Hyperosmolaric Contrast Agents in Cartilage Tomography May Expose Cartilage to Overload- Induced Cell Death
Turunen MJ, Töyräs J, Lammi MJ, Jurvelin JS, Korhonen RK. 2011. Journal of biomechanics. 45: 497-503 -
Hypotonic Challenge Alters Cell Volumes Differently in Enzymatically Treated and Intact Articular Cartilage
Turunen SM, Lammi MJ, Saarakkala S, Han S-K, Herzog W, Tanska P, Korhonen RK.. 2011. -
Hypotonic challenge modulates cell volumes differently in the superficial zone of intact articular cartilage and cartilage explant
Turunen Siru, Lammi Mikko, Saarakkala Simo, Koistinen Arto, Korhonen Rami. 2011. Biomechanics and modeling in mechanobiology. 11: 665-675 -
Implementation of Collagen Architecture from T2 Relaxation Time of MRI into a Biomechanical Model May Improve Estimation of Knee Joint Stresses
Räsänen LP, Mononen ME, Nieminen MT, Lammentausta E, Jurvelin JS, Korhonen RK. Teoksessa: Smith & Nephew, Inc.(toim.) , 2011. Transactions of Orthopaedic Research Society. s. xx. Orthopaedic Research Society -
Implementation of Collagen Architecture from T2 Relaxation Time of MRI into a Biomechanical Model May Improve Estimation of Knee Joint Stresses
Räsänen LP, Mononen ME, Nieminen MT, Lammentausta E, Jurvelin JS and Korhonen RK. 2011. -
Split-line Patterns and Structural Changes of Cartilage Control Strain and Stress Distributions Within a Knee Joint - A Patient Specific Functional Imaging Study
Mononen ME, Mikkola M, Julkunen P, Ojala R, Nieminen MT, Jurvelin JS and Korhonen RK. Teoksessa: Smith & Nephew, Inc.(toim.) , 2011. Transactions of the Annual Meeting of the Orthopaedic Research Society. ORS 2011 Annual Meeting. s. 36. -
Structural and Compositional Changes in Peri- and Extracellular Matrix of Osteoarthritic Cartilage Modulate Chondrocyte Morphology
Korhonen RK, Julkunen P, Jurvelin JS and Saarakkala S. 2011. Cellular and molecular bioengineering. 4: 484-494 -
Tietokonemallin avulla kohti parempaa nivelrikon ennaltaehkäisyä?
Rami K. Korhonen. 2011. NIVELTIETO. 4: 13 -
Cell Volume Changes in Intact Articular Cartilage and Cartilage Explants Following Hypo-osmotic Challenge
Turunen S, Lammi MJ, Saarakkala S, Koistinen A, Korhonen RK. Teoksessa: Orthopaedic Research Society(toim.) , 2010. Trans Orthop Res Soc. s. 957. -
Cell Volume Changes in Intact Articular Cartilage and Cartilage Explants Following Hypo-osmotic Challenge
Turunen SM, Lammi MJ, Saarakkala S, Koistinen A, Korhonen RK. 2010. -
Collagen Fibrillation and Reduced Proteoglycan Content of Articular Cartilage Modulate Cell Shape Changes as Osteoarthritis Progresses
Julkunen P, Saarakkala S, Korhonen RK. Teoksessa: Orthopaedic Research Society(toim.) , 2010. Tarns Orthop Res Soc. s. 792. -
Collagen Network of Cartilage Repair Tissue Modifies Intrinsic Stresses of Knee Joint Articular Cartilage
Mononen, M E; Julkunen, P; Jurvelin, J S; Kiviranta, I; Korhonen, R K. Teoksessa: Smith & Nephew, Inc.(toim.) , 2010. Transactions of the Orthopaedic Research Society. s. 914. -
Compositional Changes in the Pericellular Matrix of Human Articular Cartilage and Chondrocyte Morphology in Osteoarthritis
Mäkitalo J, Korhonen RK, Rieppo L. Jurvelin JS, Saarakkala S. Teoksessa: Orthopaedic Research Society(toim.) , 2010. Trans Orthop Res Soc. s. 791. -
Compressive and tensile properties of articular cartilage in axial loading are modulated differently by osmotic environment
Korhonen RK, Jurvelin JS. 2010. Medical engineering and physics. 32: 155-160 -
Deformation behavior of cells in articular cartilage - integration of imaging, biomechanics and modeling
Korhonen RK, Julkunen P, Turunen SM, Saarakkala S, Han S-K, Herzog W. Teoksessa: CT Lim, JCH Goh(toim.) , 2010. International Federation for Medical and Biological Engineering. s. 102. Springer -
Depth-Dependent Collagen Content, Orientation and Tensile Properties of Equine Cartilage During Growth and Maturation
Sinisaari M, Rieppo L, Iivarinen J, Brama P, Jurvelin JS, Saarakkala S, Korhonen RK, Helminen HJ. Teoksessa: Orthopaedic Research Society(toim.) , 2010. Trans Orthop Res Soc. s. 921. -
Depth-wise progression of osteoarthritis in human articular cartilage: investigation of composition, structure and biomechanics
Saarakkala S, Julkunen P, Kiviranta P, Mäkitalo J, Jurvelin JS, Korhonen RK. 2010. Osteoarthritis and cartilage. 18: 73-81 -
Diffusion coefficients of articular cartilage for different CT and MRI contrast agents
Kulmala K.A.M.,Korhonen R.K.,Julkunen P,Jurvelin J.S.,Quinn T.M.,Kröger H,Töyräs J. 2010. Medical engineering and physics. 32: 878-882 -
Diffusion of CT and MRI contrast agents in articular cartilage in vitro
Kulmala KAM, Korhonen RK, Julkunen P, Jurvelin JS, Quinn TM, Kröger H, Töyräs J. 2010. -
Effect of Degenerative Changes of Articular Cartilage on Knee Joint Stresses ¿ Functional Imaging by Combining Clinical MRI and Finite Element Modeling
Mononen, M E; Julkunen, P; Jurvelin, J S; Töyräs, J; Korhonen, R K. Teoksessa: Smith & Nephew, Inc.(toim.) , 2010. Transactions of the Orthopaedic Research Society. s. 865. -
Functional imaging of articular cartilage
Jurvelin, J S; Mononen, M E; Julkunen. Teoksessa: -(toim.) , 2010. In Proceedings of the 6th World Congress on Biomechanics. s. -. -
Osmotic Loading of in Situ Chondrocytes in Their Native Environment
Rami K Korhonen, Sang-Kuy Han, Walter Herzog. 2010. Molecular and cellular biomechanics. 7: 125-134 -
Osmotic loading of articular cartilage modulates cell deformations along primary collagen fibril directions
Korhonen RK, Han SK, Herzog W. 2010. Journal of biomechanics. 43: 783-787 -
Composition of the pericellular matrix modulates the deformation behaviour of chondrocytes in articular cartilage under static loading
Julkunen P, Wilson W, Jurvelin JS, Korhonen RK. 2009. Medical and biological engineering and computing. 47: 1281-1290 -
Importance of collagen orientation and depth-dependent fixed charge densities of cartilage on mechanical behavior of chondrocytes
Korhonen RK, Julkunen P, Wilson W, Herzog W. 2008. Journal of biomechanical engineering: transactions of the ASME. 130: 21003 -
Mechanical characterization of articular cartilage by combining magnetic resonance imaging and finite-element analysis - a potential functional imaging technique
Julkunen P, Korhonen RK, Nissi MJ, Jurvelin JS. 2008. Physics in medicine and biology. : 2425-2438 -
Characterization of articular cartilage by combining microscopic analysis with a fibril-reinforced finite-element model
Julkunen P, Kiviranta P, Wilson W, Jurvelin JS, Korhonen RK. 2007. Journal of biomechanics. 40: 1862-1870 -
Collagen network of articular cartilage modulates fluid flow and mechanical stresses in chondrocyte
Korhonen RK, Julkunen P, Rieppo J, Lappalainen R, Konttinen YT, Jurvelin JS. 2006. Biomechanics and modeling in mechanobiology. 5: 150-159 -
Can mechanical myotonometry or electromyography be used for the prediction of intramuscular pressure?
Korhonen RK, Vain A, Vanninen E, Viir R, Jurvelin JS. 2005. Physiological measurement. 26: 951-963 -
The effect of geometry and abduction angle on the stresses in cemented UHMWPE acetabular cups - finite element simulations and experimental tests
Korhonen RK, Koistinen A, Konttinen YT, Santavirta SS, Lappalainen R. 2005. Biomedical engineering online. 4: -
Experimental Analysis and Finite Element Modeling of Normal and Degraded Articular Cartilage
Korhonen R. 2003. Kuopion yliopiston julkaisuja C. Luonnontieteet ja ympäristötieteet -
Fibril reinforced poroelastic model predicts specifically mechanical behavior of normal, proteoglycan depleted and collagen degraded articular cartilage
Korhonen RK, Laasanen MS, Töyräs J, Lappalainen R, Helminen HJ, Jurvelin JS. 2003. Journal of biomechanics. 36: 1373-1379 -
Ultrasound indentation of bovine knee articular cartilage in situ
Laasanen MS, Saarakkala S, Töyräs J, Hirvonen J, Rieppo J, Korhonen RK, Jurvelin JS. 2003. Journal of biomechanics. 36: 1259-1267 -
Comparison of the equilibrium response of articular cartilage in unconfined compression, confined compression and indentation
Korhonen RK, Laasanen MS, Töyräs J, Rieppo J, Hirvonen J, Helminen HJ, Jurvelin JS. 2002. Journal of biomechanics. 35: 903-909 -
Importance of the superficial tissue layer for the indentation stiffness of articular cartilage
Korhonen RK, Wong M, Arokoski J, Lindgren R, Helminen HJ, Hunziker EB, Jurvelin JS. 2002. Medical engineering and physics. 24: 99-108 -
Novel mechano-acoustic technigue and instrument for diagnosis of cartilage degeneration
Laasanen MS, Töyräs J, Hirvonen J, Saarakkala S, Korhonen RK, Nieminen MT, Kiviranta I, Jurvelin JS. 2002. Physiological measurement. 23: 491-503 -
Real-time ultrasound analysis of articular cartilage degradation in vitro
Nieminen HJ, Töyräs J, Rieppo J, Nieminen MT, Hirvonen J, Korhonen R, Jurvelin JS. 2002. Ultrasound in medicine and biology. 28: 519-525