
REETTA KäLVIäINEN
Professor
Chair of Neurology, University of Eastern Finland
Director of Kuopio Epilepsy Center, Kuopio University Hospital, Member of EpiCARE ERN
Chair of Board, Neurocenter Finland
Reetta Kälviäinen is the Full Professor and Chair of Neurology in the University of Eastern Finland and the Director of the Kuopio Epilepsy Center in the Kuopio University Hospital. Her special research interest is clinical epileptology including identifying biomarkers of seizure activity, epileptogenesis, progression, and drug-resistancy in cohorts of newly diagnosed and drug-resistant chronic patients. These aspects of scientific projects are combined with therapeutic neuropharmacological interventions. She serves in the steering group of the European Reference Network for rare and complex epilepsies EpiCARE (of which Kuopio Epilepsy Center is a member) and co-chairs the Epilepsy Scientific Panel of the European Academy of Neurology. She is the chair of the steering group for the Establishment Phase of Neurocenter Finland.
Contact info
Organization
School of Medicine, Institute of Clinical Medicine
reetta.kalviainen@uef.fi
Phone
+358 40 583 9249
Keywords
Research groups - UEF
Links
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Twitter @rkalviainen
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LinkedIn reetta-kalviainen
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Research gate Reetta_Kaelviaeinen
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Orcid 0000-0003-2935-5131
Publications
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Zhao, Lanqing; Li, Jinwei; Kälviäinen, Reetta; Jolkkonen, Jukka; Zhao, Chuansheng. 2022. Impact of drug treatment and drug interactions in post-stroke epilepsy Pharmacology and therapeutics [In press, corrected proof]: 108030. 2022
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Kuusisto, Hanna; Kälviäinen, Reetta; Jylhä, Virpi; Saranto, Kaija. 2021. Jaettu päätöksenteko epilepsian hoidossa EPILEPSIA-LEHTI 52 3: 12 - 13. 2021
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Altmann, A; Ryten, M; Di Nunzio, M; Ravizza, T; Tolomeo, D; Reynolds, RH; Somani, A; Bacigaluppi, M; Iori, V; Micotti, E; Di Sapia, R; Cerovic, M; Palma, E; Ruffolo, G; Botía, JA; Absil, J; Alhusaini, S; Alvim, MKM; Auvinen, P; Bargallo, N; et al. [Incl. Kälviäinen, R]. 2021. A systems-level analysis highlights microglial activation as a modifying factor in common epilepsies Neuropathology and applied neurobiology 2022; 48 1: e12758. 2021
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Äikiä, Marja; Hyppönen, Jelena; Mervaala, Esa; Kälviäinen, Reetta. 2021. Cognitive functioning in progressive myoclonus epilepsy type 1 (Unverricht-Lundborg Disease, EPM1) Epilepsy and behavior 122: 108157. 2021
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Wagstyl, Konrad; Whitaker, Kirstie; Raznahan, Armin; Seidlitz, Jakob; Vértes, Petra E.; Foldes, Stephen; Humphreys, Zachary; Hu, Wenhan; Mo, Jiajie; Likeman, Marcus; Davies, Shirin; Lenge, Matteo; Cohen, Nathan T.; Tang, Yingying; Wang, Shan; Ripart, Mathilde; Chari, Aswin; Tisdall, Martin; Bargallo, Nuria; Conde-Blanco, Estefanía; et al. [Incl. Liu, Yawu; Kälviäinen, Reetta]. 2021. Atlas of lesion locations and postsurgical seizure freedom in focal cortical dysplasia: A MELD study Epilepsia 2022; 63 1: 61-74. 2021
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Sipilä, Jussi; Kälviäinen, Reetta. 2021. Unverricht-Lundborgin taudin epidemiologia Suomessa Duodecim 137 11: 1125 - 1126. 2021
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Sairanen, Joni J; Kantanen, Anne-Mari; Hyppölä, Harri T; Kälviäinen, Reetta K. 2021. Status epilepticus: Practice variation and adherence to treatment guideline in a large community hospital Journal of the neurological sciences 427: 117542. 2021
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Rissanen, Saara M; Hyppönen, Jelena; Silvennoinen, Katri; Säisänen, Laura; Karjalainen, Pasi A; Mervaala, Esa; Kälviäinen, Reetta. 2021. Wearable monitoring of positive and negative myoclonus in progressive myoclonic epilepsy type 1 Clinical neurophysiology 132 10: 2464-2472. 2021
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Sipilä, Jussi OT; Kälviäinen, Reetta. 2021. Adult-Onset Epilepsy Incidence in Finland over 34 Years: a nationwide registry-study European journal of neurology 2022; 29 2: 605-608. 2021
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Koko, Mahmoud; Krause, Roland; Sander, Thomas; Bobbili, Dheeraj Reddy; Nothnagel, Michael; May, Patrick; Lerche, Holger; Epi25 Collaborative [incl. Kälviäinen, Reetta; Auvinen, Pia; Saarela, Anni]. 2021. Distinct gene-set burden patterns underlie common generalized and focal epilepsies EBioMedicine 72: 103588. 2021
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Järvelä, Irma; Määttä, Tuomo; Acharya, Anushree; Leppälä, Juha; Jhangiani, Shalini N; Arvio, Maria; Siren, Auli; Kankuri-Tammilehto, Minna; Kokkonen, Hannaleena; Palomäki, Maarit; Varilo, Teppo; Fang, Mary; Hadley, Trevor D; Jolly, Angad; Linnankivi, Tarja; Paetau, Ritva; Saarela, Anni; Kälviäinen, Reetta; Olme, Jan; Nouel-Saied, Liz M et al.. 2021. Exome sequencing reveals predominantly de novo variants in disorders with intellectual disability (ID) in the founder population of Finland Human genetics 140 7: 1011-1029. 2021
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Jutila, Leena; Kälviäinen, Reetta; Miettinen, Riia; Immonen, Arto. 2021. Epilepsian leikkaushoito Pinsetti 33 1: 14-19. 2021
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Gleichgerrcht, E; Munsell, BC; Alhusaini, S; Alvim, MKM; Bargalló, N; Bender, B; Bernasconi, A; Bernasconi, N; Bernhardt, B; Blackmon, K; Caligiuri, ME; Cendes, F; Concha, L; Desmond, PM; Devinsky, O; Doherty, CP; Domin, M; Duncan, JS; Focke, NK; Gambardella, A; et al; [incl. Kälviäinen, R]. 2021. Artificial intelligence for classification of temporal lobe epilepsy with ROI-level MRI data: A worldwide ENIGMA-Epilepsy study Neuroimage. clinical 31: 102765. 2021
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Epilepsia. Kälviäinen, Reetta; Pesonen, Tuula, Äikiä, Marja / Kliininen neuropsykiatria (2. uudistettu painos). 2021. 2021
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Epi25 Collaborative [incl. Kälviäinen, Reetta; Timonen, Oskari]. 2021. Sub-genic intolerance, ClinVar, and the epilepsies: A whole-exome sequencing study of 29,165 individuals American journal of human genetics 108 6: 965-982. 2021
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Baumgartner, Tobias; Carreño, Mar; Rocamora, Rodrigo; Bisulli, Francesca; Boni, Antonella; Brázdil, Milan; Horak, Ondrej; Craiu, Dana; Pereira, Cristina; Guerrini, Renzo; San Antonio-Arce, Victoria; Schulze-Bonhage, Andreas; Zuberi, Sameer M; Hallböök, Tove; Kalviainen, Reetta; Lagae, Lieven; Nguyen, Sylvie; Quintas, Sofia; Franco, Ana; Cross, J Helen et al.. 2021. A survey of the European Reference Network EpiCARE on clinical practice for selected rare epilepsies Epilepsia open 6 1: 160-170. 2021
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Niestroj, Lisa-Marie; Perez-Palma, Eduardo; Howrigan, Daniel P; Zhou, Yadi; Cheng, Feixiong; Saarentaus, Elmo; Nürnberg, Peter; Stevelink, Remi; Daly, Mark J; Palotie, Aarno; Lal, Dennis; Epi25 Collaborative (incl. Kälviäinen, Reetta; Auvinen, Pia; Saarela, Anni). 2020. Epilepsy subtype-specific copy number burden observed in a genome-wide study of 17 458 subjects Brain 143 7: 2106-2118. 2020
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Vaikean epilepsian kansallinen koordinaatioryhmä; Kälviäinen, Reetta. 2020. Harvinaisepilepsiat - mistä on kyse? EPILEPSIA-LEHTI 5: 8-11. 2020
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Sisodiya, Sanjay M; Whelan, Christopher D; Hatton, Sean N; Huynh, Khoa; Altmann, Andre; Ryten, Mina; Vezzani, Annamaria; Caligiuri, Maria Eugenia; Labate, Angelo; Gambardella, Antonio; Ives-Deliperi, Victoria; Meletti, Stefano; Munsell, Brent C; Bonilha, Leonardo; Tondelli, Manuela; Rebsamen, Michael; Rummel, Christian; Vaudano, Anna Elisabetta; Wiest, Roland; Balachandra, Akshara R et al. [incl. . 2020. The ENIGMA-Epilepsy working group: Mapping disease from large data sets Human brain mapping [Online ahead of print 29 May 2020]: 1-16. 2020
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Sipilä, Jussi O T; Hyppönen, Jelena; Kytö, Ville; Kälviäinen, Reetta. 2020. Unverricht-Lundborg disease (EPM1) in Finland: A nationwide population-based study Neurology 95 23: e3117-e3123. 2020
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Schijven, Dick; Stevelink, Remi; McCormack, Mark; van Rheenen, Wouter; Luykx, Jurjen J; Koeleman, Bobby PC; Veldink, Jan H; Project MinE ALS GWAS Consortium; International League Against Epilepsy Consortium on Complex Epilepsies [incl. Kälviäinen, Reetta]. 2020. Analysis of shared common genetic risk between amyotrophic lateral sclerosis and epilepsy Neurobiology of aging 92: 153.e1-153.e5. 2020
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Rosenow, Felix; Brandt, Christian; Bozorg, Ali; Dimova, Svetlana; Steiniger-Brach, Björn; Zhang, Ying; Ferrò, Bruno; Holmes, Gregory; Kälviäinen, Reetta. 2020. Lacosamide in Patients With Epilepsy of Cerebrovascular Etiology Acta neurologica scandinavica 141 6: 473-482. 2020
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Raatikainen, M; Kälviäinen, R; Jutila, L; Äikiä, M. 2020. Cognitive functioning in new-onset juvenile myoclonic epilepsy Epilepsy and behavior 106: 107015. 2020
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Pellinen, Jacob; Tafuro, Erica; Yang, Annie; Price, Dana; Friedman, Daniel; Holmes, Manisha; Barnard, Sarah; Detyniecki, Kamil; Hegde, Manu; Hixson, John; Haut, Sheryl; Kälviäinen, Reetta; French, Jacqueline. 2020. Focal nonmotor versus motor seizures: The impact on diagnostic delay in focal epilepsy Epilepsia 61 2643-2652: 1-10. 2020
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Parviainen, Laura; Kälviäinen, Reetta; Jutila, Leena. 2020. Impact of diagnostic delay on seizure outcome in newly diagnosed focal epilepsy Epilepsia open 5 4: 605.610. 2020
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Sairanen, JJ; Kantanen, AM; Hyppölä, HT; Kälviäinen, RK. 2020. Outcome of status epilepticus and the predictive value of the EMSE and STESS scores: A prospective study Seizure: european journal of epilepsy 75: 115-120. 2020
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Mars, Nina; Widén, Elisabeth; Kerminen, Sini; Meretoja, Tuomo; Pirinen, Matti; Parolo, Pietro della Briotta; Palta, Priit; FinnGen, Palotie, Aarno; Kaprio, Jaakko; Joensuu, Heikki; Daly, Mark; Ripatti, Samuli [incl. Hiltunen, Mikko; Heikkinen, Sami; Julkunen, Valtteri; Kosma, Veli-Matti; Mannermaa, Arto; Kälviäinen, Reetta]. 2020. The role of polygenic risk and susceptibility genes in breast cancer over the course of life Nature communications 11 1: 6383. 2020
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Larivière, Sara; Rodríguez-Cruces, Raúl; Royer, Jessica; Caligiuri, Maria Eugenia; Gambardella, Antonio; Concha, Luis; Keller, Simon S; Cendes, Fernando; Yasuda, Clarissa; Bonilha, Leonardo; Gleichgerrcht, Ezequiel; Focke, Niels K; Domin, Martin; von Podewills, Felix; Langner, Soenke; Rummel, Christian; Wiest, Roland; Martin, Pascal; Kotikalapudi, Raviteja; O'Brien, Terence J; et al. [incl. Kälviä. 2020. Network-based atrophy modeling in the common epilepsies: A worldwide ENIGMA study Science advances 6 47: eabc6457. 2020
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Lamberink, Herm J; Otte, Willem M; Blümcke, Ingmar; Braun Kees P J; Aronica, Eleonora; Coras, Roland; Blumcke, Ingmar; Hamer, Hajo; Rössler, Karl; Bien, Christian G; Cloppenborg, Thomas; Grote, Alexander; Schramm, Johannes; Becker, Albert; Elger, Christian; Duncan, John S; De Tisi, Jane; Thom, Maria; Chassoux, Francine; Devaux, Bertrand [incl. Kälviäinen, Reetta]. 2020. Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis The Lancet Neurology 19 9: 748-757. 2020
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Kälviäinen, Reetta. 2020. Lääkkeiden saatavuushäiriöt ovat lisääntyneet merkittävästi EPILEPSIA-LEHTI 51 1: 17-18. 2020
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Arzimanoglou, Alexis; Brandl, Ulrich; Cross, Helen J; Gil-Nagel, Antonio; Lagae, Lieven; Johannessen Landmark, Cecilie ; Specchio, Nicola; Nabbout, Rima; Thiele, Elizabeth A; Gubbay, Oliver; The Cannabinoids International Experts Panel, Collaborators [Incl. Kälviäinen, Reetta]. 2020. Epilepsy and cannabidiol: a guide to treatment Epileptic disorders 22 1: 1-14. 2020
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Kälviäinen, Reetta. 2020. Etävastaanottoihin vauhtia koronakeväänä EPILEPSIA-LEHTI 51 4: 6-7. 2020
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Kälviäinen, Reetta. 2020. Epilepsian digihoitopolku auttaa saaman yhteyden hoitopaikkaan silloin kun on tarve EPILEPSIA-LEHTI 51 4: 4-5. 2020
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Hyppönen, J; Hakala, A; Annala, K; Zhang, H; Peltola, J; Mervaala, E; Kälviäinen, R. 2020. Automatic assessment of the myoclonus severity from videos recorded according to standardized Unified Myoclonus Rating Scale protocol and using human pose and body movement analysis Seizure: european journal of epilepsy 76: 72-78. 2020
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Epilepsiat (aikuiset). Kälviäinen, Reetta; Ansakorpi, Hanna; Immonen, Arto; Keränen, Tapani; Komulainen, Jorma; Komulainen, Sanna; Lamusuo, Salla; Peltola, Jukka / Käypä hoito -suositus. 2020. 2020
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Lehesjoki, Anna-Elina; Kälviäinen, Reetta. 2020. Progressive Myoclonic Epilepsy Type 1: 2004 Jun 24 [Updated 2020 Jul 2] Genereviews [Updated 2020 Jul 2]: 1-16. 2020
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Stevelink, Remi; Pangilinan, Faith; Jansen, Floor E; Braun, Kees PJ; Molloy, Anne M; Brody, Lawrence C; Koeleman, Bobby PC; International League Against Epilepsy Consortium on Complex Epilepsies [Incl. Kälviäinen, Reetta]. 2019. Assessing the genetic association between vitamin B6 metabolism and genetic generalized epilepsy Molecular genetics and metabolism reports 21: 100518. 2019
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Sairanen, JJ; Kantanen, AM; Hyppölä, HT; Kälviäinen, RK. 2019. Treatment delay in status epilepticus - more effective prehospital symptom recognition warranted Scandinavian journal of trauma, resuscitation and emergency medicine 27: 28. 2019
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Zelano, Johan; Klecki, Judith; Christensen, Jakob; Tomson, Torbjörn; Malmgren, Kristina; The ESBACE consortium Collaborators (incl. Kälviäinen, Reetta). 2019. The provision of epilepsy care across Europe 2017: A 17-year follow-up survey Epilepsia open 4 1: 144-152. 2019
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Strzelczyk, A; Knake, S; Kälviäinen, R; Santamarina, E; Toledo, M; Willig, S; Rohracher, A; Trinka, E; Rosenow, F. 2019. Perampanel for treatment of status epilepticus in Austria, Finland, Germany and Spain Acta neurologica scandinavica 139 4: 369-376. 2019
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Tabassum, Rubina; Ramo, Joel T; Ripatti, Pietari; Koskela, Jukka T; Kurki, Mitja; Karjalainen, Juha; Palta, Priit; Hassan, Shabbeer; Nunez-Fontarnau, Javier; Kiiskinen, Tuomo T J; Söderlund, Sanni; Matikainen, Niina; Gerl, Mathias J; Surma, Michal A; Klose, Christian; Stitziel, Nathan O; Laivuori, Hannele; Havulinna, Aki S; Service, Susan K; Salomaa, Veikko et al. (Incl Mannermaa, Arto; Heikkinen,. 2019. Genetic architecture of human plasma lipidome and its link to cardiovascular disease Nature communications 10: 4329. 2019
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Tomson, Torbjörn; Battino, Dina; Bonizzon,i Erminio; Craig, John; Lindhout, Dick; Perucca, Emilio; Sabers, Anne; Thomas, Sanjeev V; Vajda Frank; for The EURAP Study Group [incl. Kälviäinen, R]. 2019. Declining malformation rates with changed antiepileptic drug prescribing: An observational study Neurology 93 9: e831-e840. 2019
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Väätäinen, S; Soini, E; Peltola, J; Charokopou, M; Taiha, M; Kälviäinen, R. 2019. Economic Value of Adjunctive Brivaracetam Treatment Strategy for Focal Onset Seizures in Finland Advances in therapy 2020; 37 1: 477-500. 2019
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Leu, Costin; Stevelink, Remi; Smith, Alexander W; Goleva, Slavina B; Kanai, Masahiro; Ferguson, Lisa; Campbell, Ciaran; Kamatani, Yoichiro; Okada, Yukinori; Sisodiya, Sanjay M; Cavalleri, Gianpiero L; Koeleman, Bobby PC; Lerche, Holger; Jehi, Lara; Davis, Lea K; Najm, Imad M; Palotie, Aarno; Epi25 Consortium (incl. Kälviäinen, Reetta; Auvinen, Pia; Saarela, Anni). 2019. Polygenic burden in focal and generalized epilepsies Brain 142 11: 3473-3481. 2019
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Kälviäinen, Reetta. 2019. Epielpsian Käypä hoito -suositukset on päivitetty EPILEPSIA-LEHTI 50 5: 9-10. 2019
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Kälviäinen, Reetta; Reinikainen, Matti. 2019. Management of prolonged epileptic seizures and status epilepticus in palliative care patients Epilepsy and behavior 101 Part B: 106288. 2019
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Kälviäinen, Reetta. 2019. Epilepsian hoidon kehitys EPILEPSIA-LEHTI 50 4: 5-6. 2019
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Kantanen, Anne-Mari; Sairanen, Joi; Kälviäinen, Reetta. 2019. Incidence of the different stages of status epilepticus in Eastern Finland: A population-based study Epilepsy and behavior 101 Part B: 106413. 2019
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George, Allan; Kuzniecky, Ruben; Rusinek, Henry; Pardoe, Heath R.; French, Jacqueline; Lowenstein, Daniel; Cristofaro, Sabrina; McKenna, Kevin; Mays, Vickie; Shack, Darrell; Barnard, Sarah; Burke, Cheryl; Hegde, Manu; Glauser, Tracy; O'Brien, Terence; Pollard, John; Ting, Tricia; Meador, Kimford; Darby, David; Morrison, Chris et al (Incl Kälviäinen, Reetta). 2019. Standardized Brain MRI Acquisition Protocols Improve StatisticalPower in Multicenter Quantitative Morphometry Studies Journal of neuroimaging 2020; 30 1: 126-133. 2019
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Kälviäinen, Reetta; Straus, Sabine; Dogne, Jean-Michel; Bakchine, Serge; Haas, Manuel. 2018. Reducing valproate use in women with epilepsy The Lancet Neurology 17 7: 580-581. 2018
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Whelan, CD; Altmann, A; Botía, JA; Jahanshad, N; Hibar, DP; Absil, J; Alhusaini, S; Alvim, MKM; Auvinen, P; Bartolini, E; Bergo, FPG; Bernardes, T; Blackmon, K; Braga, B; Caligiuri, ME; Calvo, A; Carr, SJ; Chen, J; Chen, S; Cherubini, A; et al [Incl. Kälviäinen, R]. 2018. Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study BRAIN [ONLINE] 141 2: 391-408. 2018
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Tomson, T; Battino, D; Bonizzoni, E; Craig, J; Lindhout, D; Perucca, E; Sabers, A; Thomas, SV; Vajda, F; Faravelli, F; Pantaleoni, C; Robert-Gnansia, E; Cabral-Lim, L; Cebular, B; De Marinis, A; Kälviäinen, R; Khomeriki, K; Kiteva-Trencevska, G; Kochen, S; EURAP Study Group; et al.(incl. Kälviäinen Reetta). 2018. Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry The Lancet Neurology 17 6: 530-538. 2018
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The International League Against Epilepsy Consortium on Complex Epilepsies; [Incl. Kälviäinen, Reetta]. 2018. Genome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies Nature Communications 9: 5269. 2018
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Shorvon, SD; Bermejo, PE; Gibbs, AA; Huberfeld, G; Kälviäinen, R. 2018. Antiepileptic drug treatment of generalized tonic-clonic seizures: An evaluation of regulatory data and five criteria for drug selection. EPILEPSY & BEHAVIOR 82: 91-103. 2018
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Reijula, Emmi; Halkoaho, Arja; Pietilä, Anna-Maija; Selander, Tuomas; Martikainen, Kirsti; Kälviäinen, Reetta; Keränen, Tapani. 2018. Comparable indicators of therapeutic misconception between epilepsy or Parkinson's disease patients between those with clinical trial experience and trial non-participants. SEIZURE 60: 61-67. 2018
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Virta, LJ; Kälviäinen, R; Villikka, K; Keränen, T. 2018. Declining trend in valproate use in Finland among childbearing-aged females in 2012-2016 - a nationwide registry-based outpatient study. EUROPEAN JOURNAL OF NEUROLOGY 25 6: 869-874. 2018
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Julkunen, Petro; Löfberg, Olli; Kallioniemi, Elisa; Hyppönen, Jelena; Kälviäinen, Reetta; Mervaala, Esa. 2018. Abnormal motor cortical adaptation to external stimulus in Unverricht-Lundborg disease (progressive myoclonus type 1, EPM1) JOURNAL OF NEUROPHYSIOLOGY 120 2: 617-623. 2018
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Helmstaedter, Christoph; Beghi, Ettore; Elger, Christian E; Kälviäinen, Reetta; Malmgren, Kristina; May, Theodor W; Perucca, Emilio; Trinka, Euden; Witt, Juri-Alexander. 2018. No proof of a causal relationship between antiepileptic drug treatment and incidence of dementia. Comment on: Use of antiepileptic drugs and dementia risk - An analysis of Finnish health register and German health insurance data Epilepsia 59 7: 1303-1306. 2018
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Helmstaedter, Christoph; Beghi, Ettore; Elger, Christian E; Kälviäinen, Reetta; Malmgren, Kristina; May, Theodor W; Perucca, Emilio; Trinka, Euden; Witt, Juri-Alexander. 2018. No Evidence of a Causal Role of Antiepileptic Drug Treatment with Regard to the Development of Dementia Journal of the american geriatrics society 66 9: 1850-1852. 2018
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Ferlisi, M; Hocker, S; Trinka, E; Shorvon, S; International Steering Committee of the StEp Audit (incl. Singh, G; Kälviäinen, R; Kramer, U; Godoy, D; Newton, C; O'Brien, T; Cook, M; Rossetti, A; Groppa, S; Kumlien, E; Ercegovac, M; Yasiry, Z; Guecht, A; Wu, T; Nabbout, R; Tripathi, M; et al.). 2018. Etiologies and characteristics of refractory status epilepticus cases in different areas of the world: Results from a global audit Epilepsia 59 S2: 100-107. 2018
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Anttila, V; Bulik-Sullivan, B; Finucane, HK; Walters, RK; Bras, J; Duncan, L; Escott-Price, V; Falcone, GJ; Gormley, P; Malik, R; Patsopoulos, NA; Ripke, S; Wei, Z; Yu, D; Lee, PH; Turley, P; Grenier-Boley, B; Chouraki, V; Kamatani, Y; Berr, C; et al [Incl Kälviäinen, Reetta]. 2018. Analysis of shared heritability in common disorders of the brain Science 360 6395: eaap8757. 2018
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Baud, Maxime O; Perneger, Thomas; Racz, Attila; Pensel, Max C; Elger, Christian; Rydenhag, Bertil; Malmgren, Kristina; Cross, J Helen; McKenna, Grainne; Tisdall, Martin; Lamberink, Herm J; Rheims, Sylvain; Ryvlin, Philippe; Isnard, Jean; Mauguiere, Francois; Arzimanoglou, Alexis; Akkol, Serdar; Deniz, Kaancan; Ozkara, Cigdem; Lossius, Morten et al. [Incl Kälviäinen, Reetta]. 2018. European trends in epilepsy surgery NEUROLOGY 91 2: E96-E106. 2018
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Hynynen, J; Pokka, T; Komulainen-Ebrahim, J; Myllynen, P; Kärppä, M; Pylvänen, L; Kälviäinen, R; Sokka, A; Jyrkilä, A; Lähdetie, J; Haataja, L; Mäkitalo, A; Ylikotila, P; Eriksson, K; Haapala, P; Ansakorpi, H; Hinttala, R; Vieira, P; Majamaa, K; Rantala, H; et al. 2018. Variants p.Q1236H and p.E1143G in mitochondrial DNA polymerase gamma POLG1 are not associated with increased risk for valproate-induced hepatotoxicity or pancreatic toxicity: A retrospective cohort study of patients with epilepsy Epilepsia 59 11: 2125-2136. 2018
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Marson AG, Bolan A, Mahon J, Little A, Dickson R, Boon P, Depondt C, Martikainen J, Ryvlin P, Kälviäinen R. 2017. Cost savings and improved patient outcomes from best management of epilepsy. In: Nutt D, Boyer P, Di luca M, Oertel W (ed.) The value of treatment for brain disorders. EBC Research Project. s. 105-109. 2017
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Vogt VL, Äikiä M, del Barrio A, Boon P, Borbély C, Bran E, Braun K, Carette E, Clark M, Cross JH, Dimova P, Fabo D, Foroglou N, Francione S, Gersamia A, Gil-Nagel A, Guekht A, Harrison S, Hecimovic H, Heminghyt E et al. 2017. Current standards of neuropsychological assessment in epilepsy surgery centers across Europe. EPILEPSIA (NY) 58 3: 343-355. 2017
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The value of treatment for brain disorders. Quoidbach V, Esposito G, Destrebecq F, Kramer S, Tinelli M, Knapp M, Guldemond N, Dodel R, Gaebel W, Kälviäinen R, Kehler U, Mitsikostas D, Sørensen PS, Trenkwalder C, Vanhooren G, Visser PJ. 2017 2017
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Sokka Arja, Olsen Päivi, Kirjavainen Jarkko, Harju Maijakaisa, Keski-Nisula Leea, Räisänen Sari, Heinonen Seppo, Kälviäinen Reetta. 2017. Etiology, syndrome diagnosis, and cognition in childhood-onset epilepsy: A population-based study. Epilepsia Open 2 1: 76-83. 2017
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Reuber Markus, Kälviänen Reetta. 2017. Seizure - European Journal of Epilepsy at age 25: Where are we now and where we are going?. SEIZURE 44: 1-3. 2017
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Reijula E, Pietilä AM, Halkoaho A, Selander T, Martikainen K, Kälviäinen R, Keränen T. 2017. Clinical features of Parkinson's disease patients are associated with therapeutic misconception and willingness to participate in clinical trials. TRIALS [ONLINE] 18 1: 444. 2017
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Rauramaa Tuomas, Solomon Alina, Pikkarainen Maria, Kälviäinen Reetta, Alafuzoff Irina. 2017. Hippocampal Sclerosis and Epilepsy in Elderly Population. Journal of Alzheimers Disease & Parkinsonism 7 5: 384. 2017
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Kimiskidis Vasilios K, Tsimpiris Alkiviadis, Ryvlin Philippe, Kalviainen Reetta, Koutroumanidis Michalis, Valentin Antonio, Laskaris Nikolaos, Kugiumtzis Dimitris. 2017. TMS combined with EEG in Genetic Generalized Epilepsy: A phase II diagnostic accuracy study. CLINICAL NEUROPHYSIOLOGY 128 2: 367-381. 2017
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Kantanen A-M, Reinikainen M, Parviainen I, Kälviäinen R. 2017. Long-term outcome of refractory status epilepticus in adults: A retrospective population-based study. EPILEPSY RESEARCH 133: 13-21. 2017
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Kantanen A-M, Kälviäinen R, Parviainen I, Ala-Peijari M, Bäcklund T, Koskenkari J, Laitio R, Reinikainen M. 2017. Predictors of hospital and one-year mortality in intensive care patients with refractory status epilepticus: a population-based study. CRITICAL CARE (ONLINE) 21 1: 1-7. 2017
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Huttunen J, Lindgren A, Kurki MI, Huttunen T, Frösen J, Koivisto T, von und zu Fraunberg M, Immonen A, Jääskeläinen JE, Kälviäinen R. 2017. Epilepsy-associated long-term mortality after aneurysmal subarachnoid hemorrhage. NEUROLOGY 89 3: 263-268. 2017
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Holtkamp Martin, Beghi Ettore, Benninger Felix, Kälviäinen Reetta, Rocamora Rodrigo, Christensen Hanne. 2017. European Stroke Organisation guidelines for the management of post-stroke seizures and epilepsy. European Stroke Journal 2 2: 103-115. 2017
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Early Intervention : Bridging the Early Diagnosis and Treatment Gap - a policy white paper towards optimizing research and care for brain disorders. Mohr P, Ieven A, Arteel P, Winkler P, La Park A, Boyer P, Galderisi S, Karkkainen H, Wasserman D, Gaebel W,Jaarsma J, Dauvilliers Y, Ferri R, Rijsman R, Sakkas GK, Trenkwalder C, Oertel W, Ahmerkamp-Böhme J, Petersen G, Deuschl G, Michler F et al (incl. Kälviäinen R, Martikainen J). 2017 2017
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Bruun Emmi, Virta Lauri J, Kälviäinen Reetta, Keränen Tapani. 2017. Co-morbidity and clinically significant interactions between antiepileptic drugs and other drugs in elderly patients with newly diagnosed epilepsy. EPILEPSY & BEHAVIOR 73: 71-76. 2017
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Trinka Eugen, Kälviäinen Reetta. 2016. 25 years of advances in the definition, classification and treatment of status epilepticus. SEIZURE 2017; 44: 65-73. 2016
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Mouthaan BE, Rados M, Barsi P, Boon P, Carmichael DW, Carrette E, Craiu D, Cross JH, Diehl B, Dimova P, Fabo D, Francione S, Gaskin V, Gil-Nagel A, Grigoreva E, Guekht A, Hirsch E, Hecimovic H, Helmstaedter C, Jung et al, E-PILEPSY consortium (incl. Kälviäinen R). 2016. Current use of imaging and electromagnetic source localization procedures in epilepsy surgery centers across Europe. EPILEPSIA (NY) 57 5: 770-776. 2016
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Michelucci Roberto, Pasini Elena, Riguzzi Patrizia, Andermann Eva, Kälviäinen Reetta, Genton Pierre. 2016. Myoclonus and seizures in progressive myoclonus epilepsies: pharmacology and therapeutic trials. EPILEPTIC DISORDERS 18 S2: S145-S153. 2016
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Reuber M, Helmstaedter C, Liao W, Loddenkemper T, Thomas R, Kälviäinen R, Mann M. 2016. The future of medicine will be dark without international collaboration. SEIZURE 41 42: 1. 2016
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Kobulashvili T, Höfler J, Dobesberger J, Ernst F, Ryvlin P, Cross JH, Braun K, Dimova P, Francione S, Hecimovic H, Helmstaedter C, Kimiskidis VK, Lossius MI, Malmgren K, Marusic P, Steinhoff BJ, Boon P, Craiu D, Delanty N, Fabo D et al. 2016. Current practices in long-term video-EEG monitoring services: A survey among partners of the E-PILEPSY pilot network of reference for refractory epilepsy and epilepsy surgery. SEIZURE 38: 38-45. 2016
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Kinnunen Ulla-Mari, Kivekäs Eija, Paananen Pekka, Kälviäinen Reetta, Saranto Kaija. 2016. Testing of triggers by data mining of epilepsy patients' structured nursing records. In: Walter Sermeus, Paula M. Procter, Patrick Weber (ed.) Nursing Informatics 2016. Ios press. Studies in Health Technology and Informatics 225. s. 461-465. 2016
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Huttunen Jukka, Lindgren Antti, Kurki Mitja I, Huttunen Terhi, Frösen Juhana, von und zu Fraunberg Mikael, Koivisto Timo, Kälviäinen Reetta, Räikkönen Katri, Viinamäki Heimo, Jääskeläinen Juha E, Immonen Arto. 2016. Antidepressant Use After Aneurysmal Subarachnoid Hemorrhage: A Population-Based Case-Control Study. STROKE 47 9: 2242-8. 2016
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Crespel Arielle, Ferlazzo Edoardo, Franceschetti Silvana, Genton Pierre, Gouider Riadh, Kälviäinen Reetta, Korja Miikka, Lehtinen Maria K, Mervaala Esa, Simonato Michele, Vaarmann Annika. 2016. Unverricht-Lundborg disease. EPILEPTIC DISORDERS 18 Suppl. 2: S28-S37. 2016
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Bruun Emmi, Kälviäinen Reetta, Keränen Tapani. 2016. Outcome of initial antiepileptic drug treatment in elderly patients with newly diagnosed epilepsy. EPILEPSY RESEARCH 127: 60-65. 2016
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Kivekäs Eija, Kinnunen Ulla-Mari, Paananen Pekka, Kälviäinen Reetta, Haatainen Kaisa, Saranto Kaija. 2016. Functionality of Triggers for Epilepsy Patients Assessed by Text and Data Mining of Medical and Nursing Records. In: Sermeus Walter, Procter Paula M, Weber Patrick (ed.) Nursing Informatics 2016. Ios press. Studies in Health Technology and InformaticsY 225. s. 128-132. 2016
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Reijula Emmi, Halkoaho Arja, Pietilä Anna-Maija, Selander Tuomas, Kälviäinen Reetta, Keränen Tapani. 2015. Therapeutic misconception correlates with willingness to participate in clinical drug trials among patients with epilepsy; need for better counseling. EPILEPSY & BEHAVIOR 48: 29-34. 2015
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Könönen Mervi, Danner Nils, Koskenkorva Päivi, Kälviäinen Reetta, Hyppönen Jelena, Mervaala Esa, Karjalainen Pasi, Vanninen Ritva, Niskanen Eini. 2015. Reduced cortical activation in inferior frontal junction in Unverricht-Lundborg disease (EPM1) - A motor fMRI study. EPILEPSY RESEARCH 111: 78-84. 2015
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Muraja-Murro Anu, Mervaala Esa, Westeren-Punnonen Susanna, Lepola Pasi, Töyräs Juha, Myllymaa Sami, Julkunen Petro, Kantanen Anne-Mari, Kälviäinen Reetta, Myllymaa Katja. 2015. Forehead EEG electrode set versus full-head scalp EEG in 100 patients with altered mental state. EPILEPSY & BEHAVIOR 49: 245-249. 2015
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Tomson Torbjörn, Marson Anthony, Boon Paul, Canevini Maria Paola, Covanis Athanasios, Gaily Eija, Kälviäinen Reetta, Trinka Eugen. 2015. Valproate in the treatment of epilepsy in girls and women of childbearing potential. EPILEPSIA (NY) 56 7: 1006-10019. 2015
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Rosenow F, Kelemen A, Ben-Menachem E, McShea C, Isojarvi J, Doty P on behalf of the SP774 study investigators (incl. Reetta Kälviäinen). 2015. Long-term adjunctive lacosamide treatment in patients with partial-onset seizures. ACTA NEUROLOGICA SCANDINAVICA 133 2 (February 2016): 136-144. 2015
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Saavalainen Taavi, Jutila Leena, Mervaala Esa, Kälviäinen Reetta, Vanninen Ritva, Immonen Arto. 2015. Temporal anteroinferior encephalocele: An underrecognized etiology of temporal lobe epilepsy?. NEUROLOGY [epub ahead of print Sep 25, 2015]: -. 2015
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Tomson Torbjörn, Battino Dina, Bonizzoni Erminio, Craig John, Lindhout Dick, Perucca Emilio, Sabers Anne, Thomas Sanjeev V, Vajda Frank for the EURAP Study Group (incl. Reetta Kälviäinen). 2015. Dose-dependent teratogenicity of valproate in mono- and polytherapy : An observational study. NEUROLOGY online before print June 17, 2015. 2015
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Kälviäinen Reetta. 2015. Progressive Myoclonus Epilepsies. Seminars in Neurology 35 3: 293-299. 2015
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Kälviäinen Reetta. 2015. Tiagabine. In: Shorvon Simon D, Perucca Emilio, Engel Jerome Jr. (Eds.) (ed.) Treatment of Epilepsy (4th Edition). WILEY-BLACKWELL. s. 633-641. 2015
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Könönen Mervi, Tamsi Niko, Säisänen Laura, Kemppainen Samuli, Määttä Sara, Julkunen Petro, Jutila Leena, Äikiä Marja, Kälviäinen Reetta, Niskanen Eini, Vanninen Ritva, Karjalainen Pasi, Mervaala Esa. 2015. Non-invasive mapping of bilateral motor speech areas using navigated transcranial magnetic stimulation and functional magnetic resonance imaging. JOURNAL OF NEUROSCIENCE METHODS 248: 32-40. 2015
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Kälviäinen Reetta. 2015. Intranasal therapies for acute seizures. EPILEPSY & BEHAVIOR 49: 303-306. 2015
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Kivekäs Eija, Kinnunen Ulla-Mari, Haatainen Kaisa, Kälviäinen Reetta, Saranto Kaija. 2015. Trigger Development for the Improvement of Neurological Patient Care. In: Indra Neil Sarkar, Andrew Georgiou, Paulo Mazzoncini de Azevedo Marques (ed.) , MEDINFO 2015: eHealth-enabled Health. IOS Press. Studies in Health Technology and InformaticsY 216. s. 1116. 2015
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Kimiskidis Vasilios K, Koutlis Christos, Tsimpiris Alkiviadis, Kälviäinen Reetta, Ryvlin Philippe, Kugiumtzis Dimitris. 2015. Transcranial Magnetic Stimulation Combined with EEG Reveals Covert States of Elevated Excitability in the Human Epileptic Brain. International Journal of Neural Systems 25 5: 20 pages. 2015
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Kantanen Anne-Mari, Reinikainen Matti, Parviainen Ilkka, Ruokonen Esko, Ala-Peijari Marika, Bäcklund Tom, Koskenkari Juha, Laitio Ruut, Kälviäinen Reetta. 2015. Incidence and mortality of super-refractory status epilepticus in adults. EPILEPSY & BEHAVIOR 49: 131-134. 2015
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Hyppönen Jelena, Äikiä Marja, Joensuu Tarja, Julkunen Petro, Danner Nils, Koskenkorva Päivi, Vanninen Ritva, Lehesjoki Anna-Elina, Mervaala Esa, Kälviäinen Reetta. 2015. Refining the phenotype of Unverricht-Lundborg disease (EPM1): a population-wide Finnish study. NEUROLOGY 84 15: 1529-1536. 2015
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Huttunen Jukka, Kurki Mitja I, von und zu Fraunberg Mikael, Koivisto Timo, Ronkainen Antti, Rinne Jaakko, Jääskeläinen Juha E, Kälviäinen Reetta, Immonen Arto. 2015. Epilepsy after aneurysmal subarachnoid hemorrhage: A population-based, long-term follow-up study. NEUROLOGY 84 22: 2229-37. 2015
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Ferlisi M, Hocker S, Grade M, Trinka E, Shorvon S on behalf of the International Steering Committee of the StEp Audit (incl. Reetta Kälviäinen). 2015. Preliminary results of the global audit of treatment of refractory status epilepticus. EPILEPSY & BEHAVIOR 49: 318-324. 2015
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Bruun Emmi, Virta Lauri J, Kälviäinen Reetta, Keränen Tapani. 2015. Choice of the first anti-epileptic drug in elderly patients with newly diagnosed epilepsy: A Finnish retrospective study. SEIZURE 31: 27-32. 2015
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Baulac Michel, de Boer Hanneke, Elger Christian, Glynn Mike, Kälviäinen Reetta, Little Ann, Mifsud Janet, Perucca Emilio, Pitkänen Asla, Ryvlin Philippe. 2015. Epilepsy priorities in Europe: A report of the ILAE-IBE Epilepsy Advocacy Europe Task Force. EPILEPSIA (NY) [epub ahead of print 28 SEP 2015]: -. 2015
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Kälviäinen Reetta, Genton Pierre, Andermann Eva, Andermann Frederick, Magaudda Adriana, Frucht Steven J, Schlit Anne-Françoise, Gerard Danielle, de la Loge Christine, von Rosenstiel Philipp. 2015. Brivaracetam in Unverricht-Lundborg disease (EPM1): Results from two randomized, double-blind, placebo-controlled studies. EPILEPSIA (NY) 57 2 (2016): 210-221. 2015
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Hynynen J, Komulainen T, Tukiainen E, Nordin A, Arola J, Kälviäinen R, Jutila L, Röyttä M, Hinttala R, Majamaa K, Mäkisalo H, Uusimaa J. 2014. Acute Liver Failure After Valproate Exposure in Patients With POLG1 Mutations and the Prognosis After Liver Transplantation. LIVER TRANSPLANTATION 20 11: 1402-1412. 2014
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Kimiskidis Vasilios K, Valentin Antionio, Kälviäinen Reetta. 2014. Transcranial magnetic stimulation for the diagnosis and treatment of epilepsy. CURRENT OPINION IN NEUROLOGY (PHILADELPHIA PA) 27 2: 236-241. 2014
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Jutila Leena, Äikiä Marja, Immonen Arto, Mervaala Esa, Alafuzoff Irina, Kälviäinen Reetta. 2014. Long-term memory performance after surgical treatment of unilateral temporal lobe epilepsy (TLE). EPILEPSY RESEARCH 108 7: 1228-1237. 2014
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Anney RJ, Avbersek A, Balding D, Baum L, Becker F, Berkovic SF, Bradfield JP, Brody LC, Buono RJ, Catarino CB, Cavalleri GL, Cherny SS, Chinthapalli K, Coffey AJ, Compston A, Cossette P, de Haan G-H, De Jonghe P, de Kovel CGF, ..., Kälviäinen R, et al., International League Against Epilepsy Consortium on Complex Epilepsies ,. 2014. Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies. LANCET NEUROLOGY 13: 893-903. 2014
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Manninen O, Koskenkorva P, Lehtimäki KK, Hyppönen J, Könönen M, Laitinen T, Kalimo H, Kopra O, Kälviäinen R, Gröhn O, Lehesjoki AE, Vanninen R. 2013. White Matter Degeneration with Unverricht-Lundborg Progressive Myoclonus Epilepsy: A Translational Diffusion-Tensor Imaging Study in Patients and Cystatin B-Deficient Mice. RADIOLOGY 2013 Jun 20. [Epub ahead of print]: --. 2013
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Suoranta S, Holli-Helenius K, Koskenkorva P, Niskanen E, Könönen M, Aikiä M, Eskola H, Kälviäinen R, Vanninen R. 2013. 3D Texture Analysis Reveals Imperceptible MRI Textural Alterations in the Thalamus and Putamen in Progressive Myoclonic Epilepsy Type 1, EPM1. PLOS ONE [ONLINE] 8 7: e69905. 2013
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Räisänen S, Sokka A, Georgiadis L, Harju M, Gissler M, Keski-Nisula L, Kälviäinen R, Heinonen S. 2013. Infertility treatment and umbilical cord length-novel markers of childhood epilepsy?. PLOS ONE [ONLINE] 8 2: e55394. 2013
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Danner N, Julkunen P, Hyppönen J, Niskanen E, Säisänen L, Könönen M, Koskenkorva P, Vanninen R, Kälviäinen R, Mervaala E. 2013. Alterations of motor cortical excitability and anatomy in Unverricht-Lundborg disease. MOVEMENT DISORDERS (NEW YORK NY) 28 13: 1860-1867. 2013
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Glauser T, Ben-Menachem E, Bourgeois B, Cnaan A, Guerreiro C, Kälviäinen R, Mattson R, French JA, Perucca E, Tomson T. 2013. Updated ILAE evidence review of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes. EPILEPSIA (NY) 54 3: 551-563. 2013
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Kasperaviciute Dalia, Catarino Claudia B, Matarin Mar, Leu Costin, Novy Jan, Tostevin Anna, Leal Barbara, Hessel Ellen VS, Hallman Kerstin, Hildebrand Michael S, Dahl Hans-Henrik M, Ryten Mina, Trabzuni Daniah, Ramasamy Adaikalavan, Alhusaini Saud, Doherty Colin P, Dorn Thomas, Hansen Jörg, Krämer Gunter, Steinhoff Bernhard J, Zumsteg Dominik, Duncan Susan, Kälviäinen Reetta K et.al.. 2013. Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A. BRAIN Published online: 1-11. 2013
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Julkunen P, Säisänen L, Könönen M, Vanninen R, Kälviäinen R, Mervaala E. 2013. TMS-EEG reveals impaired intracortical interactions and coherence in Unverricht-Lundborg type progressive myoclonus epilepsy (EPM1). EPILEPSY RESEARCH S0920-1211 13: 00103-4. 2013
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Koskenkorva P, Niskanen E, Hyppönen J, Könönen M, Mervaala E, Soininen H, Kälviäinen R, Vanninen R. 2012. Sensorimotor, visual, and auditory cortical atrophy in Unverricht-Lundborg Disease mapped with cortical thickness analysis AJNR. AMERICAN JOURNAL OF NEURORADIOLOGY 33: 878-883. 2012
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Kälviäinen R, Dörfler A. 2012. Structural brain imaging. In: Stefan H, Theodore WH (ed.) , Handbook of Clinical Neurology. ss. 359-368. 2012
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Niskanen E, Könönen M, Villberg V, Nissi M, Ranta-aho P, Säisänen L, Karjalainen P, Äikiä M, Kälviäinen R, Mervaala E, Vanninen R. 2012. The effect of fMRI task combinations on determining the hemispheric dominance of language functions. NEURORADIOLOGY 54: 393-405. 2012
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Suoranta S, Manninen H, Koskenkorva P, Könönen M, Laitinen R, Lehesjoki AE, Kälviäinen R, Vanninen R. 2012. Thickened skull, scoliosis and other skeletal findings in Unverricht-Lundborg disease link cystatin B function to bone metabolism. BONE 51 6: 1016-1024. 2012
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Trinka E, Marson AG, Van Paesschen W, Kälviäinen R, Marovac J, Duncan B, Buyle S, Hallström Y, Hon P, Muscas GC, Newton M, Meencke H-J, Smith PE, Pohlmann-Eden B. 2012. KOMET: an unblinded, randomised, two parallel-group, stratified trial comparing the effectiveness of levetiracetam with controlled-release carbamazepine and extended-release sodium valproate as monotherapy in patients with newly diagnosed epilepsy. JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY - 2012 Aug 29. [Epub ahead of print]: 1-10. 2012
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Baulac M, De Boer H, Elger C, Glynn M, Kälviäinen R, Little A, Mifsud J, Perucca E, Pitkänen A. 2012. The Written Declaration on Epilepsy: An important achievement for Europe and beyond SEIZURE 21: 75-76. 2012
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Kupila L, Jutila L, Immonen A, Vanninen R, Mervaala E, Pateau A, Luostarinen L, Kälviäinen R. 2011. Late-onset Rasmussen's encephalitis and long-term remission EPILEPTIC DISORDERS 13 1: 88-91. 2011
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Walker SD, Kälviäinen R. 2011. Non-vision adverse events with vigabatrin therapy ACTA NEUROLOGICA SCANDINAVICA 124: 72-82. 2011
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Kwan P, Brodie MJ, Kälviäinen R, Yurkewicz L, Weaver J, Knapp LE. 2011. Efficacy and safety of pregabalin versus lamotrigine in patients with newly diagnosed partial seizures: a phase 3, double-blind, randomised, parallel-group trial. LANCET NEUROLOGY 10: 881-890. 2011
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Koskenkorva P, Hyppönen J, Aikiä M, Mervaala E, Kiviranta T, Eriksson K, Lehesjoki AE, Vanninen R, Kälviäinen R.. 2011. Severer phenotype in Unverricht-Lundborg disease (EPM1) patients compound heterozygous for the dodecamer repeat expansion and the c.202C>T mutation in the CSTB gene. NEURODEGENERATIVE DISEASES 8 6: 515-522. 2011
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Danner Nils, Säisänen Laura, Määttä Sara, Julkunen Petro, Hukkanen Taina, Könönen Mervi, Hyppönen Jelena, Kälviäinen Reetta, Mervaala Esa. 2011. Motor cortical plasticity is impaired in Unverrich-Lundborg disease. MOVEMENT DISORDERS (NEW YORK NY) 26 11: 2095-2100. 2011
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Danner N, Säisänen L, Määttä S, Julkunen P, Hukkanen T, Könönen M, Hyppönen J, Kälviäinen R, Mervaala E. 2011. Motor cortical plasticity is impaired in Unverricht-Lundborg Disease. MOVEMENT DISORDERS (NEW YORK NY) 26: 2095-2100. 2011
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Danner N, Julkunen P, Könönen M, Hyppönen J, Koskenkorva P, Vanninen R, Lehesjoki A-E, Kälviäinen R, Mervaala E. 2011. Primary motor cortex alterations in a compound heterozygous form of Unverricht-Lundborg disease (EPM1). SEIZURE 20: 65-71. 2011
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Musialowicz T, Mervaala E, Kälviäinen R, Uusaro A, Ruokonen E & Parviainen I. 2010. Can BIS monitoring be used to assess the depth of propofol anesthesia in the treatment of refractory status epilepticus?. EPILEPSIA (NY) 51 8: 1580-1586. 2010
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Säisänen L, Könönen M, Julkunen P, Määttä S, Vanninen R, Immonen A, Jutila L, Kälviäinen R, Jääskeläinen JE & Mervaala E. 2010. Non-invasive preoperative localization of primary motor cortex in epilepsy surgery by navigated transcranial magnetic stimulation. EPILEPSY RESEARCH 92: 134-144. 2010
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Sperling MR, Greenspan A, Cramer JA, Kwan P, Kälviäinen R, Halford JJ, Schmitt J, Yuen E et al. 2010. Carisbamate as adjunctive treatment of partial onset seizures in adults in two randomized, placebo-controlled trials. EPILEPSIA (NY) 51 3: 333-343. 2010
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Sorri I, Brigell MG, Malyusz M, Mahlamäki E, de Meynard C & Kälviäinen R. 2010. Is reduced ornithine-gamma-aminotransferase activity the cause of vigabatrin-associated visual field defects? EPILEPSY RESEARCH 92: 48-53. 2010
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Ryvlin P, Kälviäinen R, Von Raison F, Giordano S, Emir B & Chatamra K. 2010. Pregabalin in partial seizures: a pragmatic 21-week, open-label study (PREPS). EUROPEAN JOURNAL OF NEUROLOGY 17: 726-732. 2010
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Kasperaviciute D, Catarino CB, Heinzen EL, Depondt C, Cavalleri GL, Caboclo LO, Tate SK, Jamnadas-Khoda J et al. 2010. Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study. BRAIN 133: 2136-2147. 2010
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Immonen A, Jutila L, Muraja-MurroA, Mervaala E, Äikiä M, Lamusuo S, Kuikka J, Vanninen E, Alafuzoff I, Ikonen A, Vanninen R, Vapalahti M & Kälviäinen R. 2010. Long-term epilepsy surgery outcomes in patients with MRI-negative temporal lobe epilepsy. EPILEPSIA (NY) 51 11: 2260-2269. 2010
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Heinzen EL, Radtke RA, Urban TJ, Cavalleri GL, Depondt C, Need AC, Walley NM, Nicoletti P, Ge D, Catarino CB et al. 2010. Rare deletions at 16p13.11 predispose to a diverse spectrum of sporadic epilepsy syndromes. AMERICAN JOURNAL OF HUMAN GENETICS 86: 707-718. 2010
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Hakonen AH, Isohanni P, Rantamäki M, Kälviäinen R, Nordin A, Uusimaa J, Paetau A, Udd B, Pihko H & Wartiovaara A. 2010. Mitokondriaalinen resessiivinen ataksiasyndrooma ja valproaattihoidon toksisuus. DUODECIM 126: 1552-1559. 2010
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Eriksson K & Kälviäinen R. 2010. Long-term neurocognitive adverse effects of prenatal antiepileptic drug exposure. Expert Review of Clinical Pharmacology 3 1: 131-137. 2010
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Kälviäinen R. 2009. Clinical trials in status epilepticus-The clinical perspective. EPILEPSIA. SUPPLEMENT 50: 75-76. 2009
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Koskenkorva P, Khyuppenen J, Niskanen E, Könönen M, Bendel P, Mervaala E, Lehesjoki AE, Kälviäinen R, Vanninen R, Könönen M. 2009. Motor cortex and thalamic atrophy in Unverricht-Lundborg disease: Voxel-based morphometric study. NEUROLOGY 73: 606-611. 2009
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Halász P, Kälviäinen R, Mazurkiewicz-Beldrinska M, Rosenow F, Doty P, Hebert D, Sullivan T, on behalf of the SP755 STUDY Group. 2009. Adjunctive lacosamide for partial-onset seizures: Efficacy and safety from a randomized controlled trial. EPILEPSIA (NY) 50: 443-453. 2009
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Danner N, Julkunen P, Khyuppenen J, Hukkanen T, Könönen M, Säisänen L, Koskenkorva P, Vanninen R, Lehesjoki AE, Kälviäinen R, Mervaala E, Könönen M. 2009. Altered cortical inhibition in Unverricht-Lundborg type progressive myoclonus epilepsy (EPM1). EPILEPSY RESEARCH 85: 81-88. 2009
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Eriksson K, Keränen T, Kälviäinen R. 2009. Fosphenytoin. EXPERT OPINION ON DRUG METABOLISM AND TOXICOLOGY 5 6: 695-701. 2009
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O'Dushlaine CT, Dolan C, Weale ME, Stanton A, Croke DT, Kalviainen R, Eriksson K, Kantanen AM, Gibson RA, Hosford D, Sisodiya SM, Gill M, Corvin AP, Morris DW, Delanty N, Cavalleri GL. 2008. An assessment of the Irish population for large-scale genetic mapping studies involving epilepsy an other complex diseases. EUROPEAN JOURNAL OF HUMAN GENETICS 16: 176-183. 2008
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Suomalaisen Lääkäriseuran Duodecimin ja , Suomen Neurologinen Yhdistys ry:n asettama työryhmä, Kälviäinen R, Vapalahti M. 2008. Aikuisten epilepsiat DUODECIM 24: 2874-2888. 2008
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Narkilahti S, Jutila L, Alafuzoff I, Karkola K, Paljärvi L, Immonen A, Vapalahti M, Mervaala E, Kälviäinen R, Pitkänen A. 2007. Increased expression of caspase 2 in experimental and human temporal lobe epilepsy NEUROMOLECULAR MEDICINE 9 2: 129-144. 2007
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Viinikainen K, Heinonen S, Eriksson K, Kälviäinen R. 2007. Fertility in women with active epilepsy. NEUROLOGY 69: 2107-2108. 2007
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Parviainen I, Kälviäinen R, Ruokonen E. 2007. Propofol and barbiturates for the anesthesia of refractory convulsive status epilepticus: pros and cons. NEUROLOGICAL RESEARCH 29 7: 667-671. 2007
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Kälviäinen R. 2007. Status epilepticus treatment guidelines. EPILEPSIA. SUPPLEMENT 48 8: 99-102. 2007
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Kälviäinen R, Eriksson K, Losekoot M, Sorri I, Harvima I, Santavuori P, Järvelä I, Autti T, Vanninen R, Salmenperä T, van Diggelen OP. 2007. Juvenile-onset neuronal ceroid lipofuscinosis with infantile CNL1 mutation and palmitoyl-protein thioesterase deficiency. EUROPEAN JOURNAL OF NEUROLOGY 14: 369-372. 2007
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Koponen A, Seppälä U, Eriksson K, Nieminen P, Uutela A, Sillanpää M, Hyvärinen L, Kälviäinen R. 2007. Social functioning and psychological well-being of 347 young adults with epilpsy only-population-based, controlled study from Finland EPILEPSIA (NY) 48 5: 907-912. 2007
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Herrgård E, Mononen T, Mervaala E, Kuusela L, Äikiä M, Stenbäck U, Pääkkönen L, Airaksinen R-L, Kälviäinen R. 2007. More severe epilepsy and cognitive impairment in the offspring of a mother with mosaicism for the ring 20 chromosome EPILEPSY RESEARCH 73 1: 122-128. 2007
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Cavalleri GL, Weale ME, Shianna KV, Singh R, Lynch JM, Grinton B, Szoeke C, Murphy K, Kinirons P, O'Rourke D, Ge D, Depondt C, Claeys KG, Pandolfo M, Gumbs C, Walley N, McNamara J, Mulley JC, Linney KN, Sheffield LJ, Radtke RA, Tate SK, Chissoe ST, Gibson RA, Hosford D, Stanton A, Graves TD, Hanna MG, Eriksson K, Kantanen A-M, Kalviainen R, ...... 2007. Multicentre search for genetic susceptibility loci in sporadic epilepsy syndrome and seizure types: a case control-study. LANCET NEUROLOGY 6: 970-980. 2007
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Viinikainen K, Eriksson K, Mönkkönen A, Äikiä M, Nieminen P, Heinonen S, Kälviäinen R. 2006. The effects of valproate exposure in utero on behavior and the need for educational support in school-aged children EPILEPSY & BEHAVIOR 9: 636-640. 2006
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Äikiä M, Jutila L, Salmenperä T, Mervaala E, Kälviäinen R. 2006. Long-term effects of tiagabine monotherapy on cognition and mood in adult patients with chronic partial epilepsy. EPILEPSY & BEHAVIOR 8 4: 750-755. 2006
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Äikiä M, Jutila L, Salmenperä T, Mervaala E, Kälviäinen R. 2006. Comparison of the cognitive effects of tiagabine and carbamazepine as monotherapy in newly diagnosed adult patients with partial epilepsy: pooled analysis of two long-term, randomized, follow-up studies EPILEPSIA (NY) 47 7: 1121-1127. 2006
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Viinikainen K, Heinonen S, Eriksson K, Kälviäinen R. 2006. Community-based, prostective, controlled study of obstetric and neonatal outcome of 179 pregnancies in women with epilepsy. EPILEPSIA (NY) 47 1: 186-192. 2006
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Glauser T, Ben-Menachem E, Bourgeois B, Cnaan A, Chadwick D, Guerreiro C, Kalviainen R, Mattson R, Perucca E, Tomson T. 2006. ILAE treatment guidelines: evidence-based analysis of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes EPILEPSIA (NY) 47 7: 1094-1120. 2006
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Sillanpää M, Kälviäinen R, Klaukka T, Helenius H, Shinnar S. 2006. Temporal changes in the incidence of epilepsy in Finland: nationwide study. EPILEPSY RESEARCH 71: 206-215. 2006
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Parviainen I, Uusaro A, Kälviäinen R, Mervaala E, Ruokonen E. 2006. Propofol in the treatment of refractory status epilepticus. INTENSIVE CARE MEDICINE 32: 1075-1079. 2006
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Kälviäinen R, Tomson T. 2006. Optimizing treatment of epilepsy during pregnancy. NEUROLOGY. SUPPLEMENT 67 4: S59-S63. 2006
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Zhang Z, Berg M, Ikonen A, Könönen M, Kälviäinen R, Manninen H, Vanninen R, Könönen M. 2005. Carotid stenosis degree in CT angiography: assessment based on luminal area versus luminal diameter measurements. EUROPEAN RADIOLOGY 15: 2359-2365. 2005
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Sorri I, Rissanen E, Mäntyjärvi M, Kälviäinen R. 2005. Visual function in epilepsy patients treated with initial valproate monotherapy SEIZURE 14: 367-370. 2005
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Sorri I, Kälviäinen R, Mäntyjärvi M. 2005. Color vision and contrast sensitivity in epilepsy patients treated with initial tiagabine monotherapy. EPILEPSY RESEARCH 67 3: 101-107. 2005
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Sorri I, Herrgård E, Viinikainen K, Pääkkönen A, Heinonen S, Kälviäinen R. 2005. Ophthalmologic and neurologic findings in two children exposed to vigabatrin in utero EPILEPSY RESEARCH 65: 117-120. 2005
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Salmenperä T, Könönen M, Roberts N, Vanninen R, Pitkänen A, Kälviäinen R, Könönen M. 2005. Hippocampal damage in newly diagnosed focal epilepsy: a prospective MRI study. NEUROLOGY 64: 62-68. 2005
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Kälviäinen R, Eriksson K, Parviainen I. 2005. Refractory generalised convulsive status epilepticus - A guide to treatment. CNS DRUGS 19 9: 759-768. 2005
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Pirttilä TJ, Manninen A, Jutila L, Nissinen J, Kälviäinen R, Vapalahti M, Immonen A, Paljärvi L, Karkola K, Alafuzoff I, Mervaala E, Pitkänen A. 2005. Cystatin C expression is associated with granule cell dispersion in epilepsy. ANNALS OF NEUROLOGY 58 2: 211-223. 2005
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Goncalves Pereira PM, Insausti R, Artacho-Pérula E, Salmenperä T, Kälviäinen R, Pitkänen A. 2005. MR volumetric analysis of the piriform cortex and cortical amygdala in drug-refractory temporal lobe epilepsy. AJNR. AMERICAN JOURNAL OF NEURORADIOLOGY 26: 319-332. 2005
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Eriksson K, Viinikainen K, Mönkkönen A, Äikiä M, Nieminen P, Heinonen S, Kälviäinen R. 2005. Children exposed to valproate in utero-Population based evaluation of risks and confounding factors for long-term neurocognitive development EPILEPSY RESEARCH 65: 189-200. 2005
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Eriksson K, Peltola J, Kälviäinen R. 2005. Kohtausten hoidosta epilepsian hoitoon - tunnista epilepsiaoireyhtymä DUODECIM 121: 505-512. 2005
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Eriksson K, Kälviäinen R. 2005. Pharmacologic management of convulsive status epilepticus in childhood. EXPERT REVIEW OF NEUROTHERAPEUTICS 5 6: 777-783. 2005
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Berg M, Zhang Z, Ikonen A, Sipola P, Kälviäinen R, Manninen H, Vanninen R. 2005. Multi-detector row CT angiography in the assessment of carotid artery disease in the symtomatic patients: comparison with rotaional angiography and digital subtraction angiography. AJNR. AMERICAN JOURNAL OF NEURORADIOLOGY 26: 1022-1034. 2005
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Kälviäinen R. 2005. Status epilepticuksen hoito - ennusteeseen voidaan vaikuttaa tehokkaalla varhaisella hoidolla ERIKOISLÄÄKÄRI 15 6: 239-242. 2005
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Immonen A, Jutila L, Kälviäinen R, Mervaala E, Partanen K, Partanen J, Vanninen R, Ylinen A, Alafuzoff I, Paljärvi L, Hurskainen H, Rinne J, Puranen M, Vapalahti M. 2004. Preoperative clinical evaluation, outline of surgical technique and outcome in termporal lobe epilepsy ADVANCES AND TECHNICAL STANDARDS IN NEUROSURGERY 29: 87-132. 2004
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Kälviäinen R. 2003. A woman with seven monotherapies EPILEPSY & BEHAVIOR. SUPPLEMENT 4: S8-S11. 2003
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Kälviäinen R. 2002. Temporal lobe resection in a patient with severe psychiatric problems: Schmidt D, Schachter SC, 110 Puzzling Cases of Epilepsy.Martin Dunitz. 395-397. 2002
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Parviainen I, Uusaro A, Kälviäinen R, Kaukanen E, Mervaala E, Ruokonen E. 2002. High-dose thiopental in the treatment of refractory status epilepticus in intensive care unit NEUROLOGY 59: 1249-1251. 2002
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Jutila L, Immonen A, Mervaala E, Partanen J, Partanen K, Puranen M, Kälviäinen R, Alafuzoff I, Hurskainen H, Vapalahti M, Ylinen A. 2002. Long term outcome of temporal lobe epilepsy surgery: analyses of 140 consecutive patients. JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY 73: 486-494. 2002
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Kälviäinen R, Salmenperä T. 2002. Do recurrent seizures cause neuronal damage? A series of studies with MRI volumetry in adults with partial epilepsy: Sutula T, Pitkänen A, Do Seizures Damage the Brain.Elsevier. Progress in Brain Research. 279-295. 2002
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Äikiä M, Salmenperä T, Partanen K, Kälviäinen R. 2001. Verbal memory in newly diagnosed patients and patients with chronic left temporal lobe epilepsy. EPILEPSY & BEHAVIOR 2: 20-27. 2001
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Schmidt D, Arroyo S, Baulac M, Dam M, Dulac O, Friis ML, Kälviäinen R, Krämer G, van Parys J, Pedersen B, Sachdeo R. 2001. Recommendations on the clinical use of oxcarbazepine in the treatment of epilepsy: a consensus view. ACTA NEUROLOGICA SCANDINAVICA 104: 167-170. 2001
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Salmenperä T, Kälviäinen R, Partanen K, Pitkänen A. 2001. Hippocampal and amygdaloid damage in partial epilepsy A cross-sectional MRI study of 241 patients. EPILEPSY RESEARCH 46: 69-82. 2001
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Ojala M, Kälviäinen R. 2001. Insurability of patients with epilepsy: perspectives of physicians and insurance companies. In: Johannessen SI, Tomson T, Sillanpää M, Pedersen B (ed.) , Medical Risks in Epilepsy.Wrightson Biomedical Publishing. ss. 139-140. 2001
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Ojala M, Hyvärinen L, Juntunen J, Keränen T, Kälviäinen R, Mûller K, Wallin A. 2001. Epilepsia ja ajokyvyn arviointi - suomalainen menettelyohje. SUOMEN LÄÄKÄRILEHTI 56 49-50: 5121-5123. 2001
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Nousiainen I, Mäntyjärvi M, Kälviäinen R. 2001. No reversion in vigabatrin-associated visual field defects. NEUROLOGY 57: 1916-1917. 2001
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Lamusuo S, Jutila L, Ylinen A, Kälviäinen R, Mervaala E, Haaparanta M, Jääskeläinen S, Partanen K, Vapalahti M, Rinne J. 2001. [18F] FDG-PET reveals temporal hypometabolism in patients with temporal lobe epilepsy even when quantitative MRI and histopathological analysis show only mild hippocampal damage ARCHIVES OF NEUROLOGY 58: 933-939. 2001
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Kälviäinen R, Äikiä M. 2001. Kognitiiviset häiriöt neurologisissa sairauksissa. Epilepsia: Erkinjuntti T, Rinne J, Alhainen K, Soininen H, Muistihäiriöt ja dementia.Duodecim. 274-278. 2001
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Kälviäinen R. 2001. Monotherapy trial design: conversion versus de novo. EPILEPSY RESEARCH 45: 75-78. 2001
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Kälviäinen R. 2001. Long-term safety of tiagabine. EPILEPSIA. SUPPLEMENT 42 3: 46-48. 2001
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Kälviäinen R, Nousiainen I. 2001. Visual field defects with vigabatrin. Epidemiology and therapeutic implications CNS DRUGS 15 3: 217-230. 2001
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Salmenperä T, Kälviäinen R, Partanen K, Pitkänen A. 2000. Quantitative MRI volumetry of the entorhinal cortex in temporal lobe epilepsy. SEIZURE 9: 208-215. 2000
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Schmidt D, Gram L, Brodie M, Krämer G, Perucca E, Kälviäinen R, Elger CE. 2000. Tiagabine in the treatment of epilepsy - a clinical review with a guide for the prescibing physician. EPILEPSY RESEARCH 41: 245-251. 2000
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Nousiainen I, Kälviäinen R, Mäntyjärvi M. 2000. Color vision in epilepsy patients treated with vigabatrin or carbamazepine monotherapy OPHTHALMOLOGY 107: 884-888. 2000
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Salmenperä T, Kälviäinen R, Partanen K, Mervaala E, Pitkänen A. 2000. MRI volumetry of the hippocampus, amygdala, entorhinal cortex, and perirhinal cortex after status epilepticus. EPILEPSY RESEARCH 40: 155-170. 2000
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Nousiainen I, Mäntyjärvi M, Kälviäinen R. 2000. Visual function in patients with the GABAergic anticonvulsant drug tiagabine CLINICAL DRUG INVESTIGATION 20 6: 393-400. 2000
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Nousiainen I, Kälviäinen R, Mäntyjärvi M. 2000. Contrast and glare sensitivity in epilepsy patients treated with vigabatrin or carbamazepine monotherapy compared with healthy volunteers BRITISH JOURNAL OF OPHTHALMOLOGY 84: 622-625. 2000
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Chadwick D, for the Vigabatrin European Monotherapy Study Group, Kälviäinen R. 1999. Safety and efficscy of vigabatrin and carbamazepine in newly diagnosed epilepsy: a multicentre randomised double-blind study LANCET 354: 13-19. 1999
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Kälviäinen R, Nousiainen I, Mäntyjärvi M, Nikoskelainen E, Partanen J, Partanen K, Riekkinen P Sr. 1999. Vigabatrin, a gabaergic antiepileptic drug, causes concentric visual field defects. NEUROLOGY 53: 922-926. 1999
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Kälviäinen R, Pitkänen A. 1999. Prevention of seizure-induced neuronal damage and intellectual deterioration: experimental aspects and clinical implications. In: Sillanpää M, Gram L, Johannessen SI, Tomson T (ed.) , Epilepsy and Mental Retardation.Wrightson Biomedical Publishing . ss. 165 - 178. 1999
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Kälviäinen R. 1999. Cognitive effects of GABAergic antiepileptic drugs. ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY. SUPPLEMENT 50: 458-464. 1999
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Pitkänen A, Salmenperä T, Äikiä M, Partanen K, Kälviäinen R. 1999. Seizure-induced damage to the medial temporal lobe in temporal lobe epilepsy: Sillanpää M, Gram L, Johannessen SI, Tomson T, Epilepsy and Mental Retardation.Wrightson Biomedical Publishing . 147-163. 1999
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Äikiä M, Kälviäinen R, Mervaala E, Riekkinen PJ Sr. 1999. Predictors of seizure outcome in newly diagnosed partial epilepsy: memory performance as a prognostic factor. EPILEPSY RESEARCH 37: 159-167. 1999
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Kälviäinen R, Salmenperä T, Partanen K, Vainio P, Riekkinen P Sr, Pitkänen A. 1998. Recurrent seizures may cause hippocampal damage in temporal lobe epilepsy. NEUROLOGY 50: 1377-1382. 1998
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Mikkonen M, Soininen H, Kälviäinen R, Tapiola T, Ylinen A, Vapalahti M, Paljärvi L, Pitkänen A. 1998. Remodeling of neuronal circuitries in human temporal lobe epilepsy: increased expression of highly polysialylated neural cell adhesion molecule in the hippocampus and the entorhinal cortex. ANNALS OF NEUROLOGY 44: 923-934. 1998
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Pitkänen A, Tuunanen J, Kälviäinen R, Partanen K, Salmenperä T. 1998. Amygdala damage in experimental and human temporal lobe epilepsy. EPILEPSY RESEARCH 32: 233-253. 1998
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Salmenperä T, Kälviäinen R, Partanen K, Pitkänen A. 1998. Hippocampal damage caused by seizures in temporal lobe epilepsy LANCET 351: 35. 1998
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Lamusuo S, Ruottinen HM, Knuuti J, Härkönen R, Ruotsalainen U, Bergman J, Haaparanta M, Solin O, Mervaala E, Nousiainen U, Jääskeläinen S, Ylinen A, Kälviäinen R, Rinne JK, Vapalahti M, Rinne JO. 1997. Comparison of (18F) FDG-PET, (99mTc)-HMPAO-SPECT, and (123)-iomazenil-SPECT in localising the epileptogenic cortex. JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY 63: 743-748. 1997
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Kälviäinen R, Salmenperä T, Partanen K, Vainio P, Riekkinen P Sr, Pitkänen A. 1997. MRI volumetry and T2 relaxometry of the amygdala in newly diagnosed and chronic temporal lobe epilepsy. EPILEPSY RESEARCH 28: 39-50. 1997
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Lafreniére RG, Rochefort DL, Chrétien N, Rommens JM, Cochius JI, Kälviäinen R, Nousiainen U, Patry G, Farrell K, Söderfeldt B, Federico A, Hale BR, Cossio OH, Sorensen T, Pouliot MA, Kmiec T, Uldall P, Janszky J, Pranzatelli MR, Anderman F, Anderman. 1997. Unstable insertion in the 5`flanking region of the cystatin B gene is the most common mutation in progressive myoclonus epilepsy type 1, EPM1. NATURE GENETICS 15: 298-302. 1997
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Kälviäinen R, Partanen K, Äikiä M, Mervaala E, Vainio P, Riekkinen PJ Sr, Pitkänen A. 1997. MRI-based hippocampal volumetry and T2 relaxometry: correlation to verbal memory performance in newly diagnosed epilepsy patients with left-sided temporal lobe focus. NEUROLOGY 48: 286-287. 1997
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Kälviäinen R, Riekkinen PJ Sr. 1996. In reply (to Vigabatrin and carbamazepine monotherapy for newly diagnosed epilepsy). ARCHIVES OF NEUROLOGY 53: 478. 1996
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Kälviäinen R, Äikiä M, Mervaala E, Saukkonen AM, Pitkänen A, Riekkinen PJ Sr. 1996. Long-term cognitive and EEG effects of tiagabine in drug-resistant partial epilepsy. EPILEPSY RESEARCH 25: 291-297. 1996
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Kälviäinen R, Äikiä M, Riekkinen PJ Sr. 1996. Cognitive adverse effects of antiepileptic drugs. Incidence, mechanisms and therapeutic implications. CNS DRUGS 5 5: 358-368. 1996
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Pitkänen A, Laakso M, Kälviäinen R, Partanen K, Vainio P, Lehtovirta M, Riekkinen P Sr, Soininen H. 1996. Severity of hippocampal atrophy correlates with the prolongation of MRI T2 relaxation time in temporal lobe epilepsy but not in Alzheimer's disease NEUROLOGY 46: 1724-1730. 1996
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Salmenperä T, Kälviäinen R, Ylinen A, Riekkinen PJ Sr. 1996. Cost of epilepsy: review of the literature. NEUROLOGIST 2: 230-238. 1996
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Kälviäinen R, Mervaala E, Sivenius J, Riekkinen PJ Sr. 1995. Vigabatrin. Clinical use: Levy RH, Mattson RH, Meldrum BS, Antiepileptic Drugs, Fourth Edition.Raven Press. 925-930. 1995
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Kälviäinen R, Riekkinen PJ Sr. 1995. New anti-epileptic drugs. EXPERT OPINION ON INVESTIGATION DRUGS 4 10: 955-962. 1995
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Kälviäinen R, Äikiä M, Saukkonen AM, Mervaala E, Riekkinen PJ Sr. 1995. Vigabatrin vs carbamazepine monotherapy in patients with newly diagnosed epilepsy ARCHIVES OF NEUROLOGY 52: 989-996. 1995
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Ylinen A, Kälviäinen R, Riekkinen PJ Sr. 1995. Long-term efficacy and cognitive effects of vigabatrin ACTA NEUROLOGICA SCANDINAVICA. SUPPLEMENTUM 162: 47-50. 1995
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Äikiä M, Kälviäinen R, Riekkinen PJ. 1995. Verbal learning and memory in newly diagnosed partial epilepsy. EPILEPSY RESEARCH 22: 157-164. 1995
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Cochius J, Carpenter S, Andermann E, Rouleau G, Nousiainen U, Kälviäinen R, Farrell K, Andermann F. 1994. Sweat gland vacuoles in Unverricht-Lundborg disease: A clue to diagnosis? NEUROLOGY 44: 2372-2375. 1994
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Saukkonen AM, Kälviäinen R, Partanen K, Vainio P, Riekkinen P, Pitkänen A. 1994. Do seizures cause neuronal damage? A MRI study in newly diagnosed and chronic epilepsy. NEUROREPORT 6: 219-223. 1994