
STEFFI GOFFART
Senior Researcher
Contact info
Organization
Faculty of Science and Forestry, Department of Environmental and Biological Sciences
steffi.goffart@uef.fi
Phone
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Research groups - UEF
Publications
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Aasumets, Koit; Basikhina, Yuliya; Pohjoismäki, Jaakko L; Goffart, Steffi; Gerhold, Joachim. 2021. TFAM knockdown-triggered mtDNA-nucleoid aggregation and a decrease in mtDNA copy number induce the reorganization of nucleoid populations and mitochondria-associated ER-membrane contacts Biochemistry and biophysics reports 28: 101142. 2021
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Goffart, S; Tikkanen, P; Michell, C; Wilson, T; Pohjoismäki, JLO. 2021. The Type and Source of Reactive Oxygen Species Influences the Outcome of Oxidative Stress in Cultured Cells Cells 10 5: 1075. 2021
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Luzwick, Jessica W.; Dombi, Eszter; Boisvert, Rebecca A.; Roy, Sunetra; Park, Soyoung; Kunnimalaiyaan, Selvi; Goffart, Steffi; Schindler, Detlev; Schlacher, Katharina. 2021. MRE11-dependent instability in mitochondrial DNA fork protection activates a cGAS immune signaling pathway Science advances 7 51: eabf9441. 2021
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Hämäläinen, Riikka H; Landoni, Juan C; Ahlqvist, Kati J; Goffart, Steffi; Ryytty, Sanna; Rahman, M Obaidur; Brilhante, Virginia; Icay, Katherine; Hautaniemi, Sampsa; Wang, Liya; Laiho, Marikki; Suomalainen, Anu. 2020. Reply to: Proofreading deficiency in mitochondrial DNA polymerase does not affect total dNTP pools in mouse embryos Nature metabolism 2 8: 676-677. 2020
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Ankudze, Bright; Asare, Bismark; Goffart, Steffi; Koistinen, Arto; Nuutinen, Tarmo; Matikainen, Antti; Andoh, Sampson Saj; Roussey, Matthieu;, Pakkanen, Tuula. T. 2019. Hydraulically pressed silver nanowire-cotton fibers as an active platform for filtering and surface-enhanced Raman scattering detection of bacteria from fluid Applied surface science 479: 663-668. 2019
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Goffart, S; Hangas, A; Pohjoismäki, JLO. 2019. Twist and Turn - Topoisomerase Functions in Mitochondrial DNA Maintenance International journal of molecular sciences 20 8: 2041. 2019
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Hämäläinen, Riikka H; Landoni, Juan C; Ahlqvist, Kati J; Goffart, Steffi; Ryytty, Sanna; Rahman, M Obaidur; Brilhante, Virginia; lcay, Katherine; Hautaniemi, Sampsa; Wang, Liya; Laiho, Marikki; Suomalainen, Anu. 2019. Defects in mtDNA replication challenge nuclear genome stability through nucleotide depletion and provide a unifying mechanism for mouse progerias Nature metabolism 1: 958-965. 2019
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Torregrosa-Muñumer, R; Hangas, A; Goffart, S; Blei, D; Zsurka, G; Griffith, J; Kunz ,WS; Pohjoismäki, JLO. 2019. Replication fork rescue in mammalian mitochondria Scientific reports 9 1: 8785. 2019
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Yadak, Rana; Cabrera-Pérez, Raquel; Torres-Torronteras, Javier; Bugiani, Marianna; Haeck, Joost C; Huston, Marshall W; Bogaerts, Elly; Goffart, Steffi; Jacobs, Edwin H; Stok, Merel; Leonardelli, Lorena; Biasco, Luca; Verdijk, Robert M; Bernsen, Monique R; Ruijter, George; Martí, Ramon; Wagemaker, Gerard; van Til, Niek P; de Coo, Irenaeus FM. 2018. Preclinical Efficacy and Safety Evaluation of Hematopoietic Stem Cell Gene Therapy in a Mouse Model of MNGIE. Molecular Therapy - Methods and Clinical Development 8: 152-165. 2018
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Pohjoismäki, Jaakko LO; Forslund, Josefin ME; Goffart, Steffi; Torregrosa-Muñumer, Ruben; Wanrooij, Sjoerd. 2018. Known Unknowns of Mammalian Mitochondrial DNA Maintenance BIOESSAYS 40 9: 1800102. 2018