SVETLANA LAIDINEN

Contact info

Research groups - UEF

• 
  Molecular Medicine

Publications

• Vuorio, Taina; Ylä-Herttuala, Elias; Laakkonen, Johanna P; Laidinen, Svetlana; Liimatainen, Timo; Ylä-Herttuala, Seppo. 2018. Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction Scientific Reports 8: 16709. 2018
• Mutikainen Maija, Tuomainen Tomi, Naumenko Nikolay, Huusko Jenni, Smirin Boris, Laidinen S, Kokki K, Hynynen H, Ylä-Herttuala S, Heinäniemi M, Ruas JL, Tavi P. 2016. Peroxisome Proliferator-activated Receptor-gamma Coactivator 1 alfa1 Induces a Cardiac Excitation-contraction Coupling Phenotype Without Metabolic Remodelling. JOURNAL OF PHYSIOLOGY (CAMBRIDGE) 594 23: 7049-7071. 2016
• Merentie M, Lipponen JA, Hedman M, Hedman A, Hartikainen J, Huusko J, Lottonen-Raikaslehto L, Parviainen V, Laidinen S, Karjalainen PA, Ylä-Herttuala S. 2015. Mouse ECG findings in aging, with conduction system affecting drugs and in cardiac pathologies: Development and validation of ECG analysis algorithm in mice. PSYCHOLOGICAL REPORTS 3: e12639. 2015
• Ronkainen Veli-Pekka, Tuomainen Tomi, Huusko Jenni, Laidinen Svetlana, Malinen Marjo, Palvimo Jorma J, Ylä-Herttuala Seppo, Vuolteenaho Olli, Tavi Pasi. 2014. Hypoxia-inducible factor 1-induced G protein-coupled receptor 35 expression is an early marker of progressive cardiac remodelling. CARDIOVASCULAR RESEARCH 2014 Jan 1;101(1): 69-77. 2014
• Turunen Mikko P, Husso Tiia, Musthafa Haja, Laidinen Svetlana, Dragneva Galina, Laham-Karam Nihay, Honkanen Sanna, Paakinaho Anne, Laakkonen Johanna P, Gao Erhe, Vihinen-Ranta Maija, Liimatainen Timo, Ylä-Herttuala Seppo. 2014. Epigenetic upregulation of endogenous VEGF-A reduces myocardial infarct size in mice. PLOS ONE [ONLINE] 2014 Feb 26;9(2):e89979: e89979. 2014
• Kinnunen K, Heinonen SE, Kalesnykas G, Laidinen S, Uusitalo-Järvinen H, Uusitalo H, Ylä-Herttuala S. 2013. LDLR(-/-)ApoB(100/100) mice with insulin-like growth factor II overexpression reveal a novel form of retinopathy with photoreceptor atrophy and altered morphology of the retina. MOLECULAR VISION [ONLINE: HTTP://WWW.MOLVIS.ORG/MOLVIS/] 19: 1723-1733. 2013
• Sopo M, Anttila M, Sallinen H, Tuppurainen L, Laurema A, Laidinen S, Hamalainen K, Tuunanen P, Koponen JK, Kosma VM, Heinonen S, Alitalo K, Yla-Herttuala S. 2012. Antiangiogenic gene therapy with soluble VEGF-receptors -1, -2 and -3 together with paclitaxel prolongs survival of mice with human ovarian carcinoma. INTERNATIONAL JOURNAL OF CANCER 131 10: 234-2401. 2012
• Kholová Ivana, Dragneva Galina, Cermáková Petra, Laidinen Svetlana, Kaskenpää Nina, Hazes Thierry, Cermáková Eva, Steiner Ivo, Ylä-Herttuala Seppo. 2011. Lymphatic vasculature is increased in heart valves, ischaemic and inflamed hearts and in cholesterol-rich and calcified atherosclerotic lesions. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 41: 487-497. 2011
• Korpisalo P, Hytönen JP, Laitinen JT, Laidinen S, Parviainen H, Karvinen H, Siponen J, Marjomäki V, Vajanto I, Rissanen TT, Ylä-Herttuala S.. 2011. Capillary enlargement, not sprouting angiogenesis, determines beneficial therapeutic effects and side effects of angiogenic gene therapy EUROPEAN HEART JOURNAL 32: 1664-1672. 2011
• Sallinen H, Heikura T, Laidinen S, Kosma V-M, Heinonen S, Ylä-Herttuala S & Anttila M. 2010. Preoperative angiopoietin-2 serum levels. A marker of malignant potential in ovarian neoplasms and poor prognosis in epithelial ovarian cancer. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER 20 9: 1498-1505. 2010
• Kinnunen K, Kalesnykas G, Mähönen AJ, Laidinen S, Holma L, Heikura T, Airenne K, Uusitalo H, Ylä-Herttuala S, Kinnunen K, Kalesnykas G. 2009. Baculovirus is an efficient vector for the transduction of the eye: comparison of baculovirus- and adenovirus-mediated intravitreal vascular endothelial growth factor D gene transfer in the rabbit eye. JOURNAL OF GENE MEDICINE 11: 382-389. 2009
• Kinnunen K, Puustjärvi T, Teräsvirta M, Nurmenniemi P, Heikura T, Laidinen S, Paavonen T, Uusitalo H, Ylä-Herttuala S, Kinnunen K. 2009. Differences in retinal neovascular tissue and vitreous humour in patients with type 1 and type 2 diabetes. BRITISH JOURNAL OF OPHTHALMOLOGY 93: 1109-1115. 2009
• Viita H, Kinnunen K, Eriksson E, Lähteenvuo J, Babu M, Kalesnykas G, Heikura T, Laidinen S, Takalo T, Ylä-Herttuala S. 2009. Intravitreal adenoviral 15-lipoxygenase- 1 gene transfer prevents vascular endothelial growth factor A-induced neovascularization in rabbit eyes. HUMAN GENE THERAPY 20: 1679-1686. 2009
• Korpisalo P, Rissanen TT, Bengtsson T, Liimatainen T, Laidinen S, Karvinen H, Markkanen JE, Gröhn OH, Ylä-Herttuala S. 2008. Therapeutic angiogenesis with placental growth factor improves exercise tolerance of ischaemic rabbit hindlimbs. CARDIOVASCULAR RESEARCH 80 2: 263-270. 2008
• Rissanen TT, Korpisalo P, Karvinen H, Liimatainen T, Laidinen S, Gröhn OH, Ylä-Herttuala S. 2008. High-resolution ultrasound perfusion imaging of therapeutic angiogenesis. JACC: CARDIOVASCULAR IMAGING 1 1: 83 - 91. 2008
• Viita H, Markkanen J, Eriksson E, Nurminen M, Kinnunen K, Babu M, Heikura T, Turpeinen S, Laidinen S, Takalo T, Ylä-Herttuala S. 2008. 15-lipoxygenase-1 prevents vascular endothelial growth factor A- and placental growth factor-induced angiogenic effects in rabbit skeletal muscles via reduction in growth factor mRNA levels, NO bioactivity, and downregulation of VEGF receptor 2 expression. CIRCULATION RESEARCH 102: 177-184. 2008