Svetlana Laidinen - UEFConnect

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Information Publications

Research groups

Molecular Medicine 01.01.1995 -

Publications

19/19 items

ErbB signalling is a potential therapeutic target for vascular lesions with fibrous component
Jauhiainen, Suvi; Ilmonen, Henna; Vuola, Pia; Rasinkangas, Heta; Pulkkinen, Heidi H; Keränen, Sara; Kiema, Miika; Liikkanen, Jade J; Laham Karam, Nihay; Laidinen, Svetlana; Beter, Mustafa; Aavik, Einari; Lappalainen, Kimmo; Lohi, Jouko; Aronniemi, Johanna; Örd, Tiit; Kaikkonen, Minna U; Salminen, Päivi; Tukiainen, Erkki; Ylä-Herttuala, Seppo; Laakkonen, Johanna P. 2023. eLife. 12: A1 Journal article (refereed), original research
Intranasal administration of adenoviral vaccines expressing SARS-CoV-2 spike protein improves vaccine immunity in mouse models
Freitag, Tobias L; Fagerlund, Riku; Karam, Nihay Laham; Leppänen, Veli-Matti; Ugurlu, Hasan; Kant, Ravi; Mäkinen, Petri; Tawfek, Ahmed; Kumar, Sawan; Strandin, Tomas; Leskinen, Katarzyna; Hepojoki, Jussi; Kesti, Tapio; Kareinen, Lauri; Kuivanen, Suvi; Koivulehto, Emma; Sormunen, Aino; Laidinen, Svetlana; Khattab, Ayman; Saavalainen, Päivi; Meri, Seppo; Kipar, Anja; Sironen, Tarja; Vapalahti, Olli; Alitalo, Kari; Ylä-Herttuala, Seppo; Saksela, Kalle. 2023. Vaccine. 41: 3233-3246 A1 Journal article (refereed), original research
Lymphatic insufficiency leads to distinct myocardial infarct content assessed by magnetic resonance TRAFFn, T1ρ and T2 relaxation times
Ylä-Herttuala, Elias; Vuorio, Taina; Kettunen, Sanna; Laidinen, Svetlana; Ylä-Herttuala, Seppo; Liimatainen, Timo. 2023. Scientific reports. 13: . 1579 A1 Journal article (refereed), original research
Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction
Vuorio, Taina; Ylä-Herttuala, Elias; Laakkonen, Johanna P; Laidinen, Svetlana; Liimatainen, Timo; Ylä-Herttuala, Seppo. 2018. Scientific reports. 8: 16709 A1 Journal article (refereed), original research
Peroxisome Proliferator-activated Receptor-gamma Coactivator 1 alfa1 Induces a Cardiac Excitation-contraction Coupling Phenotype Without Metabolic Remodelling
Mutikainen Maija, Tuomainen Tomi, Naumenko Nikolay, Huusko Jenni, Smirin Boris, Laidinen S, Kokki K, Hynynen H, Ylä-Herttuala S, Heinäniemi M, Ruas JL, Tavi P. 2016. Journal of physiology: london. 594: 7049-7071 A1 Journal article (refereed), original research
Mouse ECG findings in aging, with conduction system affecting drugs and in cardiac pathologies: Development and validation of ECG analysis algorithm in mice
Merentie M, Lipponen JA, Hedman M, Hedman A, Hartikainen J, Huusko J, Lottonen-Raikaslehto L, Parviainen V, Laidinen S, Karjalainen PA, Ylä-Herttuala S. 2015. Psychological reports. 3: e12639 A1 Journal article (refereed), original research
Epigenetic upregulation of endogenous VEGF-A reduces myocardial infarct size in mice
Turunen Mikko P, Husso Tiia, Musthafa Haja, Laidinen Svetlana, Dragneva Galina, Laham-Karam Nihay, Honkanen Sanna, Paakinaho Anne, Laakkonen Johanna P, Gao Erhe, Vihinen-Ranta Maija, Liimatainen Timo, Ylä-Herttuala Seppo. 2014. PLoS ONE. 2014 Feb 26;9(2):e89979: e89979 A1 Journal article (refereed), original research
Hypoxia-inducible factor 1-induced G protein-coupled receptor 35 expression is an early marker of progressive cardiac remodelling
Ronkainen Veli-Pekka, Tuomainen Tomi, Huusko Jenni, Laidinen Svetlana, Malinen Marjo, Palvimo Jorma J, Ylä-Herttuala Seppo, Vuolteenaho Olli, Tavi Pasi. 2014. Cardiovascular research. 2014 Jan 1;101(1): 69-77 A1 Journal article (refereed), original research
LDLR(-/-)ApoB(100/100) mice with insulin-like growth factor II overexpression reveal a novel form of retinopathy with photoreceptor atrophy and altered morphology of the retina
Kinnunen K, Heinonen SE, Kalesnykas G, Laidinen S, Uusitalo-Järvinen H, Uusitalo H, Ylä-Herttuala S. 2013. Molecular vision. 19: 1723-1733 A1 Journal article (refereed), original research
Antiangiogenic gene therapy with soluble VEGF-receptors -1, -2 and -3 together with paclitaxel prolongs survival of mice with human ovarian carcinoma
Sopo M, Anttila M, Sallinen H, Tuppurainen L, Laurema A, Laidinen S, Hamalainen K, Tuunanen P, Koponen JK, Kosma VM, Heinonen S, Alitalo K, Yla-Herttuala S. 2012. International journal of cancer. 131: 234-2401 A1 Journal article (refereed), original research
Capillary enlargement, not sprouting angiogenesis, determines beneficial therapeutic effects and side effects of angiogenic gene therapy
Korpisalo P, Hytönen JP, Laitinen JT, Laidinen S, Parviainen H, Karvinen H, Siponen J, Marjomäki V, Vajanto I, Rissanen TT, Ylä-Herttuala S.. 2011. European heart journal. 32: 1664-1672 A1 Journal article (refereed), original research
Lymphatic vasculature is increased in heart valves, ischaemic and inflamed hearts and in cholesterol-rich and calcified atherosclerotic lesions
Kholová Ivana, Dragneva Galina, Cermáková Petra, Laidinen Svetlana, Kaskenpää Nina, Hazes Thierry, Cermáková Eva, Steiner Ivo, Ylä-Herttuala Seppo. 2011. European journal of clinical investigation. 41: 487-497 A1 Journal article (refereed), original research
Preoperative angiopoietin-2 serum levels. A marker of malignant potential in ovarian neoplasms and poor prognosis in epithelial ovarian cancer
Sallinen H, Heikura T, Laidinen S, Kosma V-M, Heinonen S, Ylä-Herttuala S & Anttila M. 2010. International journal of gynecological cancer. 20: 1498-1505 A1 Journal article (refereed), original research
Baculovirus is an efficient vector for the transduction of the eye: comparison of baculovirus- and adenovirus-mediated intravitreal vascular endothelial growth factor D gene transfer in the rabbit eye
Kinnunen K, Kalesnykas G, Mähönen AJ, Laidinen S, Holma L, Heikura T, Airenne K, Uusitalo H, Ylä-Herttuala S, Kinnunen K, Kalesnykas G. 2009. Journal of gene medicine. 11: 382-389 A1 Journal article (refereed), original research
Differences in retinal neovascular tissue and vitreous humour in patients with type 1 and type 2 diabetes
Kinnunen K, Puustjärvi T, Teräsvirta M, Nurmenniemi P, Heikura T, Laidinen S, Paavonen T, Uusitalo H, Ylä-Herttuala S, Kinnunen K. 2009. British journal of ophthalmology. 93: 1109-1115 A1 Journal article (refereed), original research
Intravitreal adenoviral 15-lipoxygenase- 1 gene transfer prevents vascular endothelial growth factor A-induced neovascularization in rabbit eyes
Viita H, Kinnunen K, Eriksson E, Lähteenvuo J, Babu M, Kalesnykas G, Heikura T, Laidinen S, Takalo T, Ylä-Herttuala S. 2009. Human gene therapy. 20: 1679-1686 A1 Journal article (refereed), original research
15-lipoxygenase-1 prevents vascular endothelial growth factor A- and placental growth factor-induced angiogenic effects in rabbit skeletal muscles via reduction in growth factor mRNA levels, NO bioactivity, and downregulation of VEGF receptor 2 expression
Viita H, Markkanen J, Eriksson E, Nurminen M, Kinnunen K, Babu M, Heikura T, Turpeinen S, Laidinen S, Takalo T, Ylä-Herttuala S. 2008. Circulation research. 102: 177-184 A1 Journal article (refereed), original research
High-resolution ultrasound perfusion imaging of therapeutic angiogenesis
Rissanen TT, Korpisalo P, Karvinen H, Liimatainen T, Laidinen S, Gröhn OH, Ylä-Herttuala S. 2008. JACC : cardiovascular imaging. 1: 83 - 91 A1 Journal article (refereed), original research
Therapeutic angiogenesis with placental growth factor improves exercise tolerance of ischaemic rabbit hindlimbs
Korpisalo P, Rissanen TT, Bengtsson T, Liimatainen T, Laidinen S, Karvinen H, Markkanen JE, Gröhn OH, Ylä-Herttuala S. 2008. Cardiovascular research. 80: 263-270 A1 Journal article (refereed), original research