Timo Leppänen
Associate Professor
Co-head of the Sleep Technology and Analytics Research Group (STAR)
Department of Technical Physics, Faculty of Science, Forestry and Technology
timo.leppanen@uef.fi | +358 50 310 1828
I started my studies in the University of Eastern Finland in 2011 after two years in the service for the Finnish Defense Forces. I got my bachelor, master and doctoral degrees in five years in 2016 at the age of 26 years and my thesis earned a grade of approved with distinction (which is awarded only if dissertation falls in the category of top 5% of its field). Since then, I have been a co-head and principal investigator in the STAG, a research team focusing on sleep-related disorders and development of novel methods and computational tools for sleep data analysis. Furthermore, I have established a wide international collaboration network with world’s top-level scientists and research infrastructures as well as companies operating at business sector. My research is mainly funded by the the Academy of Finland (Postdoctoral Researcher), Business Finland (NordicPerMed project NordSleep) and private foundations.
My research is focused on development of novel diagnostic parameters, mathematical solutions, and paradigms for severity estimation of obstructive sleep apnea. Therefore, it is very closely related to medical physics but it has also strong interface with clinical medicine. Thus, my research is a great example of interdisciplinary research in University of Eastern Finland but also of active research collaboration between University of Eastern Finland and Kuopio University Hospital.
Research groups
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Publications
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Beat-to-beat cardiac repolarization lability increases during hypoxemia and arousals in obstructive sleep apnea patients
Ebrahimian, Serajeddin; Sillanmäki, Saara; Hietakoste, Salla; Kulkas, Antti; Töyräs, Juha; Bailón, Raquel; Hernando, David; Lombardi, Carolina; Grote, Ludger; Bonsignore, Maria R; Saaresranta, Tarja; Pépin, Jean-Louis; Leppänen, Timo; Kainulainen, Samu. 2024. American journal of physiology : heart and circulatory physiology. 326: H1094-H1104 -
Increased Flow Limitation During Sleep Is Associated With Increased Psychomotor Vigilance Task Lapses in Individuals With Suspected OSA
Staykov, Eric; Mann, Dwayne L.; Duce, Brett; Kainulainen, Samu; Leppänen, Timo; Töyräs, Juha; Azarbarzin, Ali; Georgeson, Thomas; Sands, Scott A.; Terrill, Philip I.. 2024. Chest. 165: 990-1003 -
Increased flow limitation during sleep is associated with decreased psychomotor vigilance task performance in individuals with suspected obstructive sleep apnea: a multi-cohort study
Staykov, Eric; Mann, Dwayne L; Leppänen, Timo; Töyräs, Juha; Kainulainen, Samu; Azarbarzin, Ali; Duce, Brett; Sands, Scott A; Terrill, Philip I; The STAGES Cohort Investigator Group. 2024. Sleep. 47: -
Interhemispheric differences of electroencephalography signal characteristics in different sleep stages
Tashakori, Masoumeh; Rusanen, Matias; Karhu, Tuomas; Grote, Ludger; Nath, Rajdeep Kumar; Leppänen, Timo; Nikkonen, Sami. 2024. Sleep medicine. 117: 201-208 -
Nocturnal oxygen resaturation parameters are associated with cardiorespiratory comorbidities
Howarth, Timothy P; Sillanmäki, Saara; Karhu, Tuomas; Rissanen, Marika; Islind, Anna Sigridur; Hrubos-Strøm, Harald; de Chazal, Philip; Huovila, Juuso; Kainulainen, Samu; Leppänen, Timo. 2024. Sleep medicine. 118: 101-112 -
Prolonged lung-to-finger circulation time indicates an increased risk of intermittent hypoxaemia in sleep apnoea patients
Pahari, Purbanka; Korkalainen, Henri; Arnardóttir, Erna Sif; Islind, Anna Sigridur; August, Elias; Oksenberg, Arie; Töyräs, Juha; Leppänen, Timo; Nikkonen, Sami. 2024. ERJ open research. 10: . 01051-2023 -
Respiratory event index underestimates severity of sleep apnea compared to apnea-hypopnea index
Pitkänen, Minna; Nath, Rajdeep Kumar; Korkalainen, Henri; Nikkonen, Sami; Mahamid, Alaa; Oksenberg, Arie; Duce, Brett; Töyräs, Juha; Kainulainen, Samu; Leppänen, Timo. 2024. Sleep advances. 5: . zpad054 -
The role of physical activity on obstructive sleep apnea severity and hypoxic load, and the mismatch between subjective and objective physical activity assessments
Fridgeirsdottir, Katrin Y; Olafsdottir, Kristin A; Islind, Anna Sigridur; Leppänen, Timo; Arnardottir, Erna S; Saavedra, Jose M. 2024. Journal of sleep research. [Epub ahead of print 13 March 2024]: 1-9 -
Variation in the Photoplethysmogram Response to Arousal From Sleep Depending on the Cause of Arousal and the Presence of Desaturation
Luukinen, Mieli; Pitkänen, Henna; Leppänen, Timo; Töyräs, Juha; Islind, Anna Sigridur; Kainulainen, Samu; Korkalainen, Henri. 2024. IEEE journal of translational engineering in health and medicine. 12: 328-339 -
Verbal memory is linked to average oxygen saturation during sleep, not the apnea-hypopnea index nor novel hypoxic load variables
Thorisdottir, K; Hrubos-Strøm, H; Karhu, T; Nikkonen, S; Dammen, T; Nordhus, IH; Leppänen, T; Jónsdóttir, MK; Arnardottir, ES. 2024. Sleep medicine. 123: 29-36