Timo Leppänen
Associate Professor
Co-head of the Sleep Technology and Analytics Research Group (STAR)
Department of Technical Physics, Faculty of Science, Forestry and Technology
timo.leppanen@uef.fi | +358 50 310 1828
I started my studies in the University of Eastern Finland in 2011 after two years in the service for the Finnish Defense Forces. I got my bachelor, master and doctoral degrees in five years in 2016 at the age of 26 years and my thesis earned a grade of approved with distinction (which is awarded only if dissertation falls in the category of top 5% of its field). Since then, I have been a co-head and principal investigator in the STAG, a research team focusing on sleep-related disorders and development of novel methods and computational tools for sleep data analysis. Furthermore, I have established a wide international collaboration network with world’s top-level scientists and research infrastructures as well as companies operating at business sector. My research is mainly funded by the the Academy of Finland (Postdoctoral Researcher), Business Finland (NordicPerMed project NordSleep) and private foundations.
My research is focused on development of novel diagnostic parameters, mathematical solutions, and paradigms for severity estimation of obstructive sleep apnea. Therefore, it is very closely related to medical physics but it has also strong interface with clinical medicine. Thus, my research is a great example of interdisciplinary research in University of Eastern Finland but also of active research collaboration between University of Eastern Finland and Kuopio University Hospital.
Research groups
Keywords
Publications
98/98 items-
A comparative analysis of unsupervised machine‐learning methods in PSG‐related phenotyping
Ghorvei, Mohammadreza; Karhu, Tuomas; Hietakoste, Salla; Ferreira‐Santos, Daniela; Hrubos‐Strøm, Harald; Islind, Anna Sigridur; Biedebach, Luka; Nikkonen, Sami; Leppänen, Timo; Rusanen, Matias. 2024. Journal of sleep research. [First published: 24 October 2024]: 1-13 A1 Journal article (refereed), original research -
Arousal burden is highest in supine sleeping position and during light sleep
Pitkänen, Minna; Huovinen, Juho; Rissanen, Marika; Pitkänen, Henna; Kainulainen, Samu; Penzel, Thomas; Fanfulla, Francesco; Anttalainen, Ulla; Saaresranta, Tarja; Grote, Ludger; Hedner, Jan; Staats, Richard; Duce, Brett; Töyräs, Juha; Oksenberg, Arie; Leppänen, Timo. 2024. Journal of clinical sleep medicine. [Published Online October 4, 2024]: . A1 Journal article (refereed), original research -
Beat-to-beat cardiac repolarization lability increases during hypoxemia and arousals in obstructive sleep apnea patients
Ebrahimian, Serajeddin; Sillanmäki, Saara; Hietakoste, Salla; Kulkas, Antti; Töyräs, Juha; Bailón, Raquel; Hernando, David; Lombardi, Carolina; Grote, Ludger; Bonsignore, Maria R; Saaresranta, Tarja; Pépin, Jean-Louis; Leppänen, Timo; Kainulainen, Samu. 2024. American journal of physiology : heart and circulatory physiology. 326: H1094-H1104 A1 Journal article (refereed), original research -
Hypoxaemic load in sleep apnoea is associated with acute changes in T-wave amplitude
Sillanmäki, Saara; Ebrahimian, Serajeddin; Hietakoste, Salla; Hernando, David; Bailon, Raquel; Leppänen, Timo; Kainulainen, Samu. 2024. ERJ open research. 10: 00341-2024 A1 Journal article (refereed), original research -
Increased Flow Limitation During Sleep Is Associated With Increased Psychomotor Vigilance Task Lapses in Individuals With Suspected OSA
Staykov, Eric; Mann, Dwayne L.; Duce, Brett; Kainulainen, Samu; Leppänen, Timo; Töyräs, Juha; Azarbarzin, Ali; Georgeson, Thomas; Sands, Scott A.; Terrill, Philip I.. 2024. Chest. 165: 990-1003 A1 Journal article (refereed), original research -
Increased flow limitation during sleep is associated with decreased psychomotor vigilance task performance in individuals with suspected obstructive sleep apnea: a multi-cohort study
Staykov, Eric; Mann, Dwayne L; Leppänen, Timo; Töyräs, Juha; Kainulainen, Samu; Azarbarzin, Ali; Duce, Brett; Sands, Scott A; Terrill, Philip I; The STAGES Cohort Investigator Group. 2024. Sleep. 47: A1 Journal article (refereed), original research -
Interhemispheric differences of electroencephalography signal characteristics in different sleep stages
Tashakori, Masoumeh; Rusanen, Matias; Karhu, Tuomas; Grote, Ludger; Nath, Rajdeep Kumar; Leppänen, Timo; Nikkonen, Sami. 2024. Sleep medicine. 117: 201-208 A1 Journal article (refereed), original research -
Nocturnal oxygen resaturation parameters are associated with cardiorespiratory comorbidities
Howarth, Timothy P; Sillanmäki, Saara; Karhu, Tuomas; Rissanen, Marika; Islind, Anna Sigridur; Hrubos-Strøm, Harald; de Chazal, Philip; Huovila, Juuso; Kainulainen, Samu; Leppänen, Timo. 2024. Sleep medicine. 118: 101-112 A1 Journal article (refereed), original research -
Prolonged lung-to-finger circulation time indicates an increased risk of intermittent hypoxaemia in sleep apnoea patients
Pahari, Purbanka; Korkalainen, Henri; Arnardóttir, Erna Sif; Islind, Anna Sigridur; August, Elias; Oksenberg, Arie; Töyräs, Juha; Leppänen, Timo; Nikkonen, Sami. 2024. ERJ open research. 10: . 01051-2023 A1 Journal article (refereed), original research -
Respiratory event index underestimates severity of sleep apnea compared to apnea-hypopnea index
Pitkänen, Minna; Nath, Rajdeep Kumar; Korkalainen, Henri; Nikkonen, Sami; Mahamid, Alaa; Oksenberg, Arie; Duce, Brett; Töyräs, Juha; Kainulainen, Samu; Leppänen, Timo. 2024. Sleep advances. 5: . zpad054 A1 Journal article (refereed), original research