Tuure Kinnunen
Professor
Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences
tuure.kinnunen@uef.fi | +358 50 562 9349
Professor in Clinical Microbiology and Immunology, Specialist in Clinical Microbiology.
Research focus: human immunology, especially immune dysfunction in autoimmune diseases.
Twitter: @kinnunenlab
Research groups
Academic Degrees
- Docent (adjunct professor, immunology), University of Eastern Finland, 2013
- Specialist in Clinical Microbiology, University of Eastern Finland, 2012
- PhD (Immunology), University of Kuopio, 2007
- MD, University of Kuopio, 2005
- MSc (Biotechnology), University of Kuopio, 2000
Major Positions and Appointments
- Academy Researcher, University of Eastern Finland, 2016-2020
- Clinical Instructor, University of Eastern Finland, 2012-2016
- Post-doctoral fellow, Yale University, USA, 2010-2011
- Post-doctoral fellow, University of Kuopio, 2007-2009
- Researcher, University of Kuopio 2000-2006
Publications
51 items-
DNA methylation differences within INS, PTPN22 and IL2RA promoters in lymphocyte subsets in children with type 1 diabetes and controls
Pahkuri, Sirpa; Ekman, Ilse; Vandamme, Céline; Näntö-Salonen, Kirsti; Toppari, Jorma; Veijola, Riitta; Knip, Mikael; Kinnunen, Tuure; Ilonen, Jorma; Lempainen, Johanna. 2023. Autoimmunity. 56: 1-8 -
Evaluation of plasma IL-21 as a potential biomarker for type 1 diabetes progression
Schroderus, Anna-Mari; Poorbaugh, Josh; McElyea, Samantha; Beasley, Stephanie; Zhang, Lin; Näntö-Salonen, Kirsti; Rintamäki, Reeta; Pihlajamäki, Jussi; Knip, Mikael; Veijola, Riitta; Toppari, Jorma; Ilonen, Jorma; Benschop, Robert J; Kinnunen, Tuure. 2023. Frontiers in immunology. 14: . 1157265 -
Skin, gut, and sand metagenomic data on placebo-controlled sandbox biodiversity intervention study
Roslund, Marja I; Parajuli, Anirudra; Hui, Nan; Puhakka, Riikka; Grönroos, Mira; Soininen, Laura; Nurminen, Noora; Oikarinen, Sami; Cinek, Ondřej; Kramná, Lenka; Schroderus, Anna-Mari; Laitinen, Olli H; Kinnunen, Tuure; Hyöty, Heikki; Sinkkonen, Aki. 2023. Data in brief. 47: -
A Placebo-controlled double-blinded test of the biodiversity hypothesis of immune-mediated diseases: Environmental microbial diversity elicits changes in cytokines and increase in T regulatory cells in young children
Roslund, Marja I.; Parajuli, Anirudra; Hui, Nan; Puhakka, Riikka; Grönroos, Mira; Soininen, Laura; Nurminen, Noora; Oikarinen, Sami; Cinek, Ondřej; Kramná, Lenka; Schroderus, Anna-Mari; Laitinen, Olli H.; Kinnunen, Tuure; Hyöty, Heikki; Sinkkonen, Aki; Cerrone, Damiano; Grönroos, Mira; Laitinen, Olli H.; Luukkonen, Anna; Mäkelä, Iida; Nurminen, Noora; Oikarinen, Sami; Parajuli, Anirudra; Puhakka, Riikka; Roslund, Marja I.; Saarenpää, Mika; Soininen, Laura; Rajaniemi, Juho; Hyöty, Heikki; Sinkkon. 2022. Ecotoxicology and environmental safety. 242: -
Single-cell characterization of dog allergen–specific T cells reveals TH2 heterogeneity in allergic individuals
Vandamme, C; Rytkönen-Nissinen, M; Lönnberg, T; Randell, J; Harvima RJ; Kinnunen, T; Virtanen, T. 2022. Journal of allergy and clinical immunology. 149: 1732-1743.e15 -
Generation of self-reactive, shared T-cell receptor α chains in the human thymus
Heikkilä, Nelli; Sormunen, Silja; Mattila, Joonatan; Härkönen, Taina; Knip, Mikael; Ihantola, Emmi-Leena; Kinnunen, Tuure; Mattila, Ilkka P.; Saramäki, Jari; Arstila, T. Petteri. 2021. Journal of autoimmunity. 119: 102616 -
B-cell helper T cells and type 1 diabetes
Vandamme, Céline; Kinnunen, Tuure. 2020. Scandinavian journal of immunology. 92: e12943 -
Biodiversity intervention enhances immune regulation and health-associated commensal microbiota among daycare children
Roslund, Marja I; Puhakka, Riikka; Grönroos, Mira; Nurminen, Noora; Oikarinen, Sami; Gazali, Ahmad M; Cinek, Ondrej; Kramná, Lenka; Siter, Nathan; Vari, Heli K; Soininen, Laura; Parajuli, Anirudra; Rajaniemi, Juho; Kinnunen, Tuure; Laitinen, Olli H; Hyöty, Heikki; Sinkkonen, Aki, ADELE research group. 2020. Science advances. 6: eaba2578 -
Characterization of Proinsulin T Cell Epitopes Restricted by Type 1 Diabetes-Associated HLA Class II Molecules
Ihantola, Emmi-Leena; Ilmonen, Henna; Kailaanmäki, Anssi; Rytkönen-Nissinen, Marja; Azam, Aurélien; Maillère, Bernard; Lindestam Arlehamn, Cecilia; Sette, Alessandro; Motwani, Keshav; Seay, Howard; Brusko, Todd; Knip, Mikael; Veijola, Riitta; Toppari, Jorma; Ilonen, Jorma; Kinnunen, Tuure. 2020. Journal of immunology. 204: 2349-2359 -
Mucosal-associated invariant T cell alterations during the development of human type 1 diabetes
Gazali, Ahmad M; Schroderus, Anna-Mari; Näntö-Salonen, Kirsti; Rintamäki, Reeta; Pihlajamäki, Jussi; Knip, Mikael; Veijola, Riitta; Toppari, Jorma; Ilonen, Jorma; Kinnunen, Tuure. 2020. Diabetologia. 63: 2396-2409