UMA THANIGAI ARASU
Postdoctoral Researcher
Studying the extracellular matrix and functional changes of the adipose tissue during atherosclerosis.
Contact info
Organization
Faculty of Health Sciences, A.I. Virtanen Institute for Molecular Sciences
uma.thanigai@uef.fi
Phone
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Research groups - UEF
Links
Publications
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Thanigai Arasu, Uma (ed.) . 2020. Hyaluronan-coated extracellular vesicles : regulation of their secretion and interaction with their target cells. Itä-Suomen yliopisto. Publications of the University of Eastern Finland. Dissertations in Health Sciences 557. 2020
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Arasu, Uma Thanigai; Härkönen, Kai; Koistinen, Arto; Rilla, Kirsi. 2019. Correlative light and electron microscopy is a powerful tool to study interactions of extracellular vesicles with recipient cells Experimental cell research 376 2: 149-158. 2019
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Arasu, UT; Deen, AJ; Pasonen-Seppänen, S; Heikkinen, S; Lalowski, M; Kärnä, R; Härkönen, K; Mäkinen, P; Lázaro-Ibáñez, E; Siljander, PR; Oikari, S; Levonen, AL; Rilla, K. 2019. HAS3-induced extracellular vesicles from melanoma cells stimulate IHH mediated c-Myc upregulation via the hedgehog signaling pathway in target cells Cellular and molecular life sciences [Published: 09 December 2019]: 1-23. 2019
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Härkönen, K; Oikari, S; Kyykallio, H; Capra, J; Hakkola, S; Ketola, K; Thanigai Arasu, U; Daaboul, G; Malloy, A; Oliveira, C; Jokelainen, O; Sironen, R; Hartikainen, JM; Rilla, K. 2019. CD44s Assembles Hyaluronan Coat on Filopodia and Extracellular Vesicles and Induces Tumorigenicity of MKN74 Gastric Carcinoma Cells Cells 8 3: 276. 2019
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Melero-Fernandez de Mera, RM; Arasu, UT; Kärnä, R; Oikari, S; Rilla, K; Vigetti, D; Passi, A; Heldin, P; Tammi, MI; Deen, AJ. 2019. Effects of mutations in the post-translational modification sites on the trafficking of hyaluronan synthase 2 (HAS2) Matrix biology 80: 85-103. 2019
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Rilla, Kirsi; Mustonen, Anne-Mari; Thanigai, Arasu Uma; Härkönen, Kai; Matilainen, Johanna; Nieminen, Petteri. 2019. Extracellular vesicles are integral and functional components of the extracellular matrix Matrix biology 75-76: 201-219. 2019
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Arasu UT, Kärnä R, Härkönen K, Oikari S, Koistinen A, Kröger H, Qu C, Lammi MJ, Rilla K. 2017. Human mesenchymal stem cells secrete hyaluronan-coated extracellular vesicles. MATRIX BIOLOGY 64: 54-68. 2017
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Koistinen Ville, Härkönen Kai, Kärnä Riikka, Arasu Uma Thanigi, OIkari Sanna, Rilla Kirsi. 2017. EMT induced by EGF and wounding activates hyaluronan synthesis machinery and EV shedding in rat primary mesothelial cells. MATRIX BIOLOGY 63: 38-54. 2017
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Lazaro-Ibanez Elisa, Neuvonen Maarit, Takatalo Maarit, Arasu Uma Thanigai, Capasso Cristian, Cerullo Vincenzo, Rhim Johng S, Rilla Kirsi, Yliperttula Marjo, Siljander Pia R -M. 2017. Metastatic state of parent cells influences the uptake and functionality of prostate cancer cell-derived extracellular vesicles. Journal of Extracellular Vesicles 6 1: 1354645. 2017
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Deen AJ, Arasu UT, Pasonen-Seppänen S, Hassinen A, Takabe P, Wojciechowski S, Kärnä R, Rilla K, Kellokumpu S, Tammi R, Tammi M, Oikari S. 2016. UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression. CELLULAR AND MOLECULAR LIFE SCIENCES: CMLS 73 16: 3183-3204. 2016