Uma Thanigai Arasu
Postdoctoral Researcher
Studying the extracellular matrix and functional changes of the adipose tissue during atheroscle...
A.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences
uma.thanigai@uef.fi
Research groups
Projects
Publications
17/17 items-
An abdominal obesity missense variant in the adipocyte thermogenesis gene TBX15 is implicated in adaptation to cold in Finns
Deal, Milena; Kar, Asha; Lee, Seung Hyuk T.; Alvarez, Marcus; Rajkumar, Sandhya; Arasu, Uma Thanigai; Kaminska, Dorota; Männistö, Ville; Heinonen, Sini; van der Kolk, Birgitta W.; Säiläkivi, Ulla; Saarinen, Tuure; Juuti, Anne; Pihlajamäki, Jussi; Kaikkonen, Minna U.; Laakso, Markku; Pietiläinen, Kirsi H.; Pajukanta, Päivi. 2024. American journal of human genetics. 111: 2542-2560 A1 Journal article (refereed), original research -
Increased secretion of adipocyte-derived extracellular vesicles is associated with adipose tissue inflammation and the mobilization of excess lipid in human obesity
Matilainen, Johanna; Berg, Viivi; Vaittinen, Maija; Impola, Ulla; Mustonen, Anne-Mari; Männistö, Ville; Malinen, Marjo; Luukkonen, Veera; Rosso, Natalia; Turunen, Tanja; Käkelä, Pirjo; Palmisano, Silvia; Arasu, Uma Thanigai; Sihvo, Sanna P.; Aaltonen, Niina; Härkönen, Kai; Caddeo, Andrea; Kaminska, Dorota; Pajukanta, Päivi; Kaikkonen, Minna U.; Tiribelli, Claudio; Käkelä, Reijo; Laitinen, Saara; Pihlajamäki, Jussi; Nieminen, Petteri; Rilla, Kirsi. 2024. Journal of translational medicine. 22: . 623 A1 Journal article (refereed), original research -
Oncogenic KEAP1 mutations activate TRAF2-NFκB signaling to prevent apoptosis in lung cancer cells
Deen, Ashik Jawahar; Adinolfi, Simone; Härkönen, Jouni; Patinen, Tommi; Liu, Xiaonan; Laitinen, Tuomo; Takabe, Piia; Kainulainen, Kirsi; Pasonen-Seppänen, Sanna; Gawriyski, Lisa M; Arasu, Uma Thanigai; Selvarajan, Ilakya; Mäkinen, Petri; Laitinen, Hanna; Kansanen, Emilia; Kaikkonen, Minna U; Poso, Antti; Varjosalo, Markku; Levonen, Anna-Liisa. 2024. Redox biology. 69: A1 Journal article (refereed), original research -
Single nucleus RNA-sequencing integrated into risk variant colocalization discovers 17 cell-type-specific abdominal obesity genes for metabolic dysfunction-associated steatotic liver disease
Lee, Seung Hyuk T; Garske, Kristina M; Arasu, Uma Thanigai; Kar, Asha; Miao, Zong; Alvarez, Marcus; Koka, Amogha; Darci-Maher, Nicholas; Benhammou, Jihane N; Pan, David Z; Örd, Tiit; Kaminska, Dorota; Männistö, Ville; Heinonen, Sini; Wabitsch, Martin; Laakso, Markku; Agopian, Vatche G; Pisegna, Joseph R; Pietiläinen, Kirsi H; Pihlajamäki, Jussi; Kaikkonen, Minna U; Pajukanta, Päivi. 2024. EBioMedicine. 106: . 105232 A1 Journal article (refereed), original research -
Single-Cell Gene-Regulatory Networks of Advanced Symptomatic Atherosclerosis
Mocci, Giuseppe; Sukhavasi, Katyayani; Örd, Tiit; Bankier, Sean; Singha, Prosanta; Arasu, Uma Thanigai; Agbabiaje, Olayinka Oluwasegun; Mäkinen, Petri; Ma, Lijiang; Hodonsky, Chani J; Aherrahrou, Redouane; Muhl, Lars; Liu, Jianping; Gustafsson, Sonja; Byandelger, Byambajav; Wang, Ying; Koplev, Simon; Lendahl, Urban; Owens, Gary; Leeper, Nicholas J; Pasterkamp, Gerard; Vanlandewijck, Michael; Michoel, Tom; Ruusalepp, Arno; Hao, Ke; Ylä-Herttuala, Seppo; Väli, Marika; Järve, Heli; Mokry, Michal; C. 2024. Circulation research. 134: 1405-1423 A1 Journal article (refereed), original research -
Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease
Darci-Maher, Nicholas; Alvarez, Marcus; Arasu, Uma Thanigai; Selvarajan, Ilakya; Lee, Seung Hyuk T.; Pan, David Z.; Miao, Zong; Das, Sankha Subhra; Kaminska, Dorota; Örd, Tiit; Benhammou, Jihane N.; Wabitsch, Martin; Pisegna, Joseph R.; Männistö, Ville; Pietiläinen, Kirsi H.; Laakso, Markku; Sinsheimer, Janet S.; Kaikkonen, Minna U.; Pihlajamäki, Jussi; Pajukanta, Päivi. 2023. EBioMedicine. 92: A1 Journal article (refereed), original research -
Exploring the genetic basis of coronary artery disease using functional genomics
López Rodríguez, Maykel; Arasu, Uma Thanigai; Kaikkonen, Minna U. 2023. Atherosclerosis. 374: 87-98 A2 Review article, Literature review, Systematic review -
Hyaluronan-coated extracellular vesicles : regulation of their secretion and interaction with their target cells
Thanigai Arasu, Uma. 2020. Publications of the University of Eastern Finland. Dissertations in Health Sciences G5 Doctoral dissertation (article) -
CD44s Assembles Hyaluronan Coat on Filopodia and Extracellular Vesicles and Induces Tumorigenicity of MKN74 Gastric Carcinoma Cells
Härkönen, K; Oikari, S; Kyykallio, H; Capra, J; Hakkola, S; Ketola, K; Thanigai Arasu, U; Daaboul, G; Malloy, A; Oliveira, C; Jokelainen, O; Sironen, R; Hartikainen, JM; Rilla, K. 2019. Cells. 8: 276 A1 Journal article (refereed), original research -
Correlative light and electron microscopy is a powerful tool to study interactions of extracellular vesicles with recipient cells
Arasu, Uma Thanigai; Härkönen, Kai; Koistinen, Arto; Rilla, Kirsi. 2019. Experimental cell research. 376: 149-158 A1 Journal article (refereed), original research