In translational dentistry, the goal is to perform multi-disciplinary research to enhance the translation of scientific knowledge to clinical dental practice and to identify research requirements from the clinical practice to be brought to the laboratory. The aim is to encourage and promote collaboration between laboratory and clinical researchers. The objective is to clarify how oral inflammations and dysbiosis contribute to the risk of general chronic health problems. On the other hand, the aim is to spread the word among medical practitioners and the general audience on the systemic risks associated with oral infections.
Publications
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Burden of oral diseases predicts development of excess weight in early adolescence: a 2-year longitudinal study
Lommi, Sohvi; Leinonen, Jukka; Pussinen, Pirkko; Furuholm, Jussi; Kolho, Kaija-Leena; Viljakainen, Heli. 2024. European journal of pediatrics. 183: 4093-4101 A1 Journal article (refereed), original research -
Multikingdom oral microbiome interactions in early-onset cryptogenic ischemic stroke
Manzoor, Muhammed; Leskelä, Jaakko; Pietiäinen, Milla; Martinez-Majander, Nicolas; Ylikotila, Pauli; Könönen, Eija; Niiranen, Teemu; Lahti, Leo; Sinisalo, Juha; Putaala, Jukka; Pussinen, Pirkko J; Paju, Susanna. 2024. ISME communications. 4: A1 Journal article (refereed), original research -
Periodontitis, Dental Procedures, and Young-Onset Cryptogenic Stroke
Leskelä, J; Putaala, J; Martinez-Majander, N; Tulkki, L; Manzoor, M; Zaric, S; Ylikotila, P; Lautamäki, R; Saraste, A; Suihko, S; Könönen, E; Sinisalo, J; Pussinen, P J; Paju, S. 2024. Journal of dental research. 103: 494-501 A1 Journal article (refereed), original research -
Serum MMP-8 and TIMP-1 concentrations in a population-based cohort: effects of age, gender, and health status
Ranta, Julia; Havulinna, Aki S; Tervahartiala, Taina; Niemi, Katriina; Aarabi, Ghazal; Vihervaara, Terhi; Salomaa, Veikko; Sorsa, Timo; Pussinen, Pirkko J; Salminen, Aino. 2024. Frontiers in dental medicine. 5: A1 Journal article (refereed), original research -
Shotgun metagenomic analysis of the oral microbiome in gingivitis: a nested case-control study
Manzoor, Muhammed; Leskelä, Jaakko; Pietiäinen, Milla; Martinez-Majander, Nicolas; Könönen, Eija; Niiranen, Teemu; Lahti, Leo; Sinisalo, Juha; Putaala, Jukka; Pussinen, Pirkko J.; Paju, Susanna. 2024. Journal of oral microbiology. 16: 1-13 A1 Journal article (refereed), original research -
Suunterveys heijastuu veren aineenvaihduntatuotteiden tasapainoon
Salminen, Aino; Määttä, Anne-Mari; Mäntylä, Päivi; Leskelä, Jaakko; Pietiläinen, Milla; Buhlin, Kåre; Suominen, Liisa; Paju, Susanna; Sattler, Wolfgang; Sinisalo, Juha; Pussinen, Pirkko. 2024. Suomen hammaslääkärilehti. 31: 24 D1 Article in a trade journal -
Dietary inflammatory index in relation to salivary cytokine concentrations and periodontitis: A cross-sectional analysis
Syrjäläinen, Sanna; Männistö, Satu; Könönen, Eija; Pussinen, Pirkko; Gürsoy, Mervi; Suominen, Anna Liisa; Jousilahti, Pekka; Gürsoy, Ulvi Kahraman. 2023. Journal of clinical periodontology. 2024; 51: 406-416 A1 Journal article (refereed), original research -
FinnGen provides genetic insights from a well-phenotyped isolated population
Kurki, Mitja I.; Karjalainen, Juha; Palta, Priit; Sipilä, Timo P.; Kristiansson, Kati; Donner, Kati M.; Reeve, Mary P.; Laivuori, Hannele; Aavikko, Mervi; Kaunisto, Mari A.; Loukola, Anu; Lahtela, Elisa; Mattsson, Hannele; Laiho, Päivi; Della Briotta Parolo, Pietro; Lehisto, Arto A.; Kanai, Masahiro; Mars, Nina; Rämö, Joel; Kiiskinen, Tuomo; Heyne, Henrike O.; Veerapen, Kumar; Rüeger, Sina; Lemmelä, Susanna; Zhou, Wei; Ruotsalainen, Sanni; Pärn, Kalle; Hiekkalinna, Tero; Koskelainen, Sami; Paaja. 2023. Nature. 613: 508-518 A1 Journal article (refereed), original research -
Localization and expression profiles of gingival monocyte chemoattractant protein-1-induced protein-1 (MCPIP-1) and mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT-1)
Yu, Lili; Firatli, Yigit; Elmanfi, Samira; Gürsoy, Mervi; Özdemir Kabalak, Meltem; Kasnak, Gökhan; Pussinen, Pirkko; Bikker, Floris J.; Caglayan, Feriha; Firatli, Erhan; Gürsoy, Ulvi Kahraman. 2023. Clinical oral investigations. 27: 2065-2074 A1 Journal article (refereed), original research -
Parodontiitin vaihe ja riskiluokka yhteydessä verenpainetautiriskiin
Yildirim, Burak; Aksit, Cemilenur; Mutlu, Mesut; Ainola, Mari; Eklund, Kari; Leskelä, Jaakko; Pussinen, Pirkko; Beklen, Arzu. 2023. Suomen hammaslääkärilehti. 30: 25 D1 Article in a trade journal