Pirkko J. Pussinen
Deputy Head of Unit
Professor
Professor of translational dentistry
Institute of Dentistry, School of Medicine, Faculty of Health Sciences
In translational dentistry, the goal is to perform multi-disciplinary research to enhance the translation of scientific knowledge to clinical dental practice and to identify research requirements from the clinical practice to be brought to the laboratory. The aim is to encourage and promote collaboration between laboratory and clinical researchers. The objective is to clarify how oral inflammations and dysbiosis contribute to the risk of general chronic health problems. On the other hand, the aim is to spread the word among medical practitioners and the general audience on the systemic risks associated with oral infections.
Publications
42/42 items-
Denture-associated oral microbiome in dentate and edentulous older adults living in long-term care facilities
Manzoor, Muhammed; Pussinen, Pirkko J; Saarela, Riitta KT; Pitkälä, Kaisu; Hiltunen, Kaija; Mäntylä, Päivi, 2026, Journal of oral microbiology, 18, 1, 2641915. A1 Journal article (refereed), original research -
Microbial burden of periodontal diseases and its clinical application: The stage, grade, and furcation matter
Dong, Anbo; Paju, Susanna; Leskelä, Jaakko; Manzoor, Muhammed; Putaala, Jukka; Ylikotila, Pauli; Könönen, Eija; Pussinen, Pirkko; Zaric, Svetislav, 2026, Journal of periodontology, [First published: 17 May 2026], 1-14. A1 Journal article (refereed), original research -
Modulation of LPS-associated virulence activity for reduction of periodontal inflammatory burden
Dong, Anbo; Lehto, Markku; Putaala, Jukka; Paju, Susanna; Pussinen, Pirkko; Zaric, Svetislav, 2026, Frontiers in microbiology, 17, 1728315. A1 Journal article (refereed), original research -
Obstructive sleep apnea and periodontitis: a systematic review with considerations on CPAP therapy
Kukila, Aida; Manzoor, Muhammed; Salminen, Aino; Mäntylä, Päivi; Pussinen, Pirkko, 2026, Acta odontologica scandinavica, 85, 453-459. A2 Review article, Literature review, Systematic review -
Oral microbiota and periodontal health: the oral–brain axis in cognitive ageing
Pussinen, Pirkko; Manzoor, Muhammed, 2026, EBioMedicine, 126, 106234. B1 Non-refereed journal articles -
Periodontitis and Endotoxemia: Clinical and Microbiological Insights
Dong, Anbo; Manzoor, Muhammed; Leskelä, Jaakko; Putaala, Jukka; Könönen, Eija; Jin, Yi; Pussinen, Pirkko; Paju, Susanna; Zaric, Svetislav, 2026, Journal of clinical periodontology, 53, 8, 1344-1354. A1 Journal article (refereed), original research -
Serum TIMP-1 concentrations are associated with cancer incidence and cancer-related mortality in a population-based cohort
Nieminen, MT; Brandt, E; Havulinna, AS; Kambur, O; Tervahartiala, T; Zeller, T; Blankenberg, S; Salomaa, V; Sorsa, T; Pussinen, PJ; Salminen, A, 2026, Scientific reports, 16, 23048. A1 Journal article (refereed), original research -
Shotgun Metagenomic Analysis Reveals Taxonomic and Functional Transitions in the Salivary Microbiome During Periodontal Disease Progression
Manzoor, Muhammed; Leskela, Jaakko; Kononen, Eija; Lahti, Leo; Putaala, Jukka; Pussinen, Pirkko J; Paju, Susanna, 2026, Journal of clinical periodontology, [First published: 09 August 2026], 1-13. A1 Journal article (refereed), original research -
Systemic Lipidomics Identifies Altered Ceramide-Phospholipid Balance Associated With Periodontitis Severity: A Cross-Sectional Study With 12-Year Follow-Up
Tuomivaara, Minja; Halme, Anne-Mari; Manzoor, Muhammed; Salasuo, Elina; Paju, Susanna; Mäntylä, Päivi; Buhlin, Kåre; Lahdentausta-Suomalainen, Laura; Laaksonen, Reijo; Sinisalo, Juha; Pussinen, Pirkko; Salminen, Aino, 2026, Journal of clinical periodontology, [Epub ahead of print 2 Aug 2026], 1-12. A1 Journal article (refereed), original research -
Association of Subgingival Microbiota Composition With Risk, Severity, and Outcome of Cryptogenic Ischemic Stroke in Young Adults
Manzoor, Muhammed; Zaric, Svetislav; Dong, Anbo; Leskelä, Jaakko; Pietiäinen, Milla; Könönen, Eija; Ylikotila, Pauli; Enzinger, Christian; Ropele, Stefan; Gattringer, Thomas; Eppinger, Sebastian; Sinisalo, Juha; Putaala, Jukka; Pussinen, Pirkko J; Paju, Susanna, 2025, Journal of the american heart association: Cardiovascular and cerebrovascular disease, 14, 24, e043495. A1 Journal article (refereed), original research