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Raili Riikonen

Raili Riikonen

Professor, Emerita

Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences

[email protected]

Information Publications

Publications

70/70 items

Biochemical mechanisms in pathogenesis of infantile epileptic spasm syndrome
Riikonen, Raili, 2023, Seizure: european journal of epilepsy, 105, 1-9. A2 Review article, Literature review, Systematic review
Could prevention of infantile spasms have been possible in a historical cohort of 31 tuberous sclerosis patients?
Riikonen, Raili, 2021, European journal of paediatric neurology, 35, 153-157. A1 Journal article (refereed), original research
Insulin-Like Growth Factors in the Pathogenesis and Treatment of Neurological Disorders in Children
Riikonen, Raili, 2021, Gan, Yong X, New Visions in Science and Technology Vol. 3, 30-49. A3 Book section, Chapters in research books
Teleneurology based management of Infantile spasms during COVID-19 pandemic: a consensus report by the South Asia Allied West Syndrome Research Group
Madaan, Priyanka; Kumar Sahu, Jitendra; Wanigasinghe, Jithangi; Fatema, Kanij; Linn, Kyaw; Lhamu Mynak, Mimi; Garófalo Gómez, Nicolás; Samia, Pauline; Poudel, Prakash; Chand, Prem; Riikonen, Raili for the South Asia Allied West Syndrome Research Group, 2021, Epilepsy & behavior reports, 15, 100423. A1 Journal article (refereed), original research
18q12.3-q21.1 Microdeletion Detected in the Prenatally Alcohol-Exposed Dizygotic Twin With Discordant Fetal Alcohol Syndrome Phenotype
Kahila, Hanna; Marjonen, Heidi; Auvinen, Pauliina; Avela, Kristiina; Riikonen, Raili; Kaminen-Ahola, Nina, 2020, Molecular genetics & genomic medicine, 8, 4, e1192. A1 Journal article (refereed), original research
ACTH treatment of infantile spasms: Low-moderate vs high dose, natural vs synthetic ACTH. A retrospective study
Riikonen, Raili; Lähdetie, Jaana; Kokki, Hannu, 2020, Pediatric neurology, 111, 46-50. A1 Journal article (refereed), original research
Infantile Spasms: Outcome in Clinical Studies
Riikonen, Raili, 2020, Pediatric neurology, 108, 54-64. A2 Review article, Literature review, Systematic review
Management practices for West syndrome in South Asia: A survey study and meta-analysis
Madaan, Priyanka; Chand, Prem; Linn, Kyaw; Wanigasinghe, Jithangi; Lhamu Mynak, Mimi; Poudel, Prakash; Riikonen, Raili; Kumar, Amit; Dhir, Pooja; Negi, Sandeep; Sahu, Jitendra Kumar, 2020, Epilepsia open, 5, 3, 461-474. A1 Journal article (refereed), original research
Rett Syndrome: Search for Prognostic Factors
Kokki, Hannu; Vanhala, Raija; Riikonen, Raili, 2020, Neurology and neurobiology, [Epub ahead of print 24 Jan 2020], 1-8. A1 Journal article (refereed), original research
Is adrenocorticotropic hormone (ACTH) therapy loaded with severe side effects? Do not use synthetic ACTH at the same dosages as "natural" ACTH
Riikonen, Raili, 2019, Epilepsia, 60, 7, 1482-1482. B1 Non-refereed journal articles
CSF nerve growth factor (ß-NGF) is increased but CSF insulin-like growth factor-(IGF-1) is normal in children with tuberous sclerosis and infantile spasms
Riikonen, Raili; Kokki, Hannu, 2018, European journal of paediatric neurology, 2019; 23, 1, 191-196. A1 Journal article (refereed), original research
Insulin-Like Growth Factors in the Pathogenesis of Neurological Diseases in Children
Riikonen Raili, 2017, International journal of molecular sciences, 18, 10, 2056. A2 Review article, Literature review, Systematic review
Combination therapy for treatment of infantile spasms
Riikonen Raili, 2016, The Lancet Neurology, 2017; 16, 1, 19-20. A1 Journal article (refereed), original research
Long-term mortality of patients with West syndrome
Sillanpää Matti, Riikonen Raili, Saarinen Maiju M, Schmidt Dieter, 2016, Epilepsia open, 1, 1-2, 61-66. A1 Journal article (refereed), original research
Treatment of autistic spectrum disorder with insulin-like growth factors
Riikonen Raili, 2016, European journal of paediatric neurology, 20, 6, 816-823. A2 Review article, Literature review, Systematic review
WONOEP appraisal: Molecular and cellular biomarkers for epilepsy
Walker Lauren E, Janigro Damir, Heinemann Uwe, Riikonen Raili, Bernard Christophe, Patel Manisha, 2016, Epilepsia, 57, 9, 1354-1362. A2 Review article, Literature review, Systematic review
Does vigabatrin treatment for infantile spasms cause visual field defects? An international multicentre study
Riikonen R, Rener-Primec Z, Carmant L, Dorofeeva M, Hollody K, Szabo I, Krajnc BS, Wohlrab G, Sorri I, 2015, Developmental medicine and child neurology, 57, 1, 60-67. A1 Journal article (refereed), original research
High-Lights of Epilepsy 2015
Riikonen Raili, 2015, Journal of Systems and Integrative Neuroscience, 1, 2. B1 Non-refereed journal articles
Infantile spasms and 15q11.2q13.1 chromosome duplication in two successive generations
Riikonen Raili Sylvia, Wallden Tiina, Kokkonen Hannaleena, 2015, European journal of paediatric neurology, 2016; 20, 1, 164-167. A1 Journal article (refereed), original research
Long-term outcome in children with infantile spasms treated with vigabatrin: A cohort of 180 patients
Riikonen Raili, 2015, Epilepsia, 56, 5, 807-809. B1 Non-refereed journal articles
Long-term outcome in pyridoxine-responsive infantile epilepsy
Riikonen R, Mankinen K, Gaily E, 2015, European journal of paediatric neurology, 19, 6, 647-651. A1 Journal article (refereed), original research
Psychological distress of children with early-onset type 1 diabetes and their mothers' well-being
Hannonen R, Eklund K, Tolvanen A, Komulainen J, Riikonen R, Delamater AM, Ahonen T, 2015, Acta paediatrica, 104, 11, 1144-9. A1 Journal article (refereed), original research
Serotonin and dopamine transporter binding in children with autism determined by SPECT
Makkonen I, Riikonen R, Kokki H, Airaksinen MM, Kuikka JT, 2008, Developmental medicine and child neurology, 50, 593-597. A1 Journal article (refereed), original research
Neurotrophic factors in the pathenogenesis of neurological disorders with mental retardation in children
Riikonen R, 2007, Current pediatric reviews, 3, 3, 207-213. A1 Journal article (refereed), original research
Nosological aspects of West syndrome
Riikonen R, 2007, Guzzetta F, Dalla Bernadina B, Guerrini R, Progress in Epileptic Spasms and West syndrome, 1-14. A3 Book section, Chapters in research books
Cerebrospinal fluid insulin-like growth factors IGF-1 and IGF-2 in infantile autism
Riikonen R, Makkonen I, Vanhala R, Turpeinen U, Kuikka J, Kokki H, 2006, Developmental medicine and child neurology, 48, 751-755. A1 Journal article (refereed), original research
Childhood convulsive status epilepticus
Riikonen R, 2006, The Lancet.
Insulin-like growth factor delivery across the blood-brain barrier
Riikonen R, 2006, Chemotherapy, 52, 279-281. A1 Journal article (refereed), original research
Therapy and outcome of infants with infantile spasms
Riikonen R, 2006, 10th International Child Neurology Congress. International Proceedings, 51-57. A4 Conference proceedings
Analysis of four neuroligin genes as candidates for autism
Ylisaukko-oja T, Rehnström K, Auranen M, Vanhala R, Alen R, Kempas E, Ellonen P, Turunen JA, Makkonen I, Riikonen R, Nieminen-von Wendt T, von Wendt L, Peltonen L, Järvelä I, 2005, European journal of human genetics, 13, 1285-1292. A1 Journal article (refereed), original research
Cerebrospinal fluid insulin-like growth factor 1 is low in acute and chronic white-matter diseases of children
Riikonen R, Turpeinen U, 2005, Journal of child neurology, 20, 181-184. A1 Journal article (refereed), original research
Deep serotonergic and dopaminergic structures in fetal alcoholic syndrome: A study with nor-beeta-CIT-single-photon emission computed tomography and magnetic resonance imaging volumetry
Riikonen RS, Nokelainen P, Valkonen K, Kolehmainen AI, Kumpulainen KI, Könönen M, Vanninen R-LS, Kuikka JT, 2005, Biological psychiatry, 57, 1565-1572. A1 Journal article (refereed), original research
The latest on infantile spasms
Riikonen R, 2005, Current opinion in neurology, 18, 91-95. A2 Review article, Literature review, Systematic review
Cerebrospinal fluid insulin-like growth factor (IGF-1) and insulin-like growth factor binding protein (IGFBP-2) in children with acute lymphoblastic leukemia
Riikonen R, Vettenranta K, Riikonen P, Turpeinen U, Saarinen-Pihkala UM, 2004, Pediatric blood and cancer, 43, 110-114. A1 Journal article (refereed), original research
Cerebrospinal fluid insulin-like growth factor-1, insulin growth factor binding protein-2 or nitric oxide are not increased in MS or ALS
Pirttilä T, Vanhatalo S, Turpeinen U, Riikonen R, Pirttilä T, 2004, Acta neurologica scandinavica, 109, 337-341. A1 Journal article (refereed), original research
Comparison of regional cerebral perfusion, EEG and cognitive functions in type 1 diabetic children with and without severe hypoglycaemia
Tupola S, Salonen I, Hannonen R, Verho S, Saar P, Riikonen R, 2004, European journal of pediatrics, 163, 335-336. A2 Review article, Literature review, Systematic review
Infantile spasms: Therapy and outcome
Riikonen R, 2004, Journal of child neurology, 19, 401-404. A2 Review article, Literature review, Systematic review
Lasten päänsärky
Suomen Lastenneurologinen Yhdistys ry:n asettama työryhmä, Riikonen R, 2003, Duodecim, 119, 16, 1592-1598. A1 Journal article (refereed), original research
Neurocognitive functioning in children with type-1 diabetes with and without episodes of severe hypoglycaemia
Hannonen R, Tupola S, Ahonen T, Riikonen R, 2003, Developmental medicine and child neurology, 45, 262-268. A1 Journal article (refereed), original research
Neurotrophic factors in the pathogenesis of Rett syndrome
Riikonen R, 2003, Journal of child neurology, 18, 693-697. A1 Journal article (refereed), original research
Vertebral artery insufficiency as a possible mechanism for sudden infant death - in vivo evidence does not support findings from postmortem studies
Vanhatalo S, Nikolajev K, Kiekara O, Seuri R, Riikonen R, 2003, Brain and development, 25, 322-325. A1 Journal article (refereed), original research
Diabetesta sairastavat lapset ja oppimisvaikeudet
Hannonen R, Tupola S, Ahonen T, Riikonen R, 2002, NMI-bulletin, 12, 2, 15-19. D1 Article in a trade journal
ACTH therapy of West syndrome: Finnish views
Riikonen R, 2001, Brain and development, 23, 642-646. A2 Review article, Literature review, Systematic review
Epidemiological data of West syndrome in Finland
Riikonen R, 2001, Brain and development, 23, 539-541. A2 Review article, Literature review, Systematic review
Long-term outcome of patients with West syndrome
Riikonen R, 2001, Brain and development, 23, 683-687. A2 Review article, Literature review, Systematic review
Low levels of insulin-like growth factor-I in cerebrospinal fluid in children with autism
Vanhala R, Turpeinen U, Riikonen R, 2001, Developmental medicine and child neurology, 43, 614-616. A1 Journal article (refereed), original research
MECP2 gene analysis in classical Rett syndrome and in patients with Rett-like features
Auranen M, Vanhala R, Vosman M, Levander M, Varilo T, Hietala M, Riikonen R, Peltonen L, Järvelä I, 2001, Neurology, 56, 611-617. A1 Journal article (refereed), original research
Neurotrophic factors in the pathogenesis of Rett syndrome
Riikonen R, 2001, Kerr A, Engerström IW, Rett Disorder and the Developing Brain, 127-129. A3 Book section, Chapters in research books
Nitric oxide metabolites, nitrates and nitrites in the cerebrospinal fluid in children with west syndrome
Vanhatalo S, Riikonen R, 2001, Epilepsy research, 46, 3-13. A1 Journal article (refereed), original research
Reversed visual field constrictions in children after vigabatrin withdrawal-true retinal recovery or improved test performance only?
Vanhatalo S, Alen R, Riikonen R, Rantala H, Aine M-R, Mustonen K, Nousiainen I, 2001, Seizure: european journal of epilepsy, 10, 7, 508-511. A1 Journal article (refereed), original research
The PEHO syndrome
Riikonen R, 2001, Brain and development, 23, 765-769. A2 Review article, Literature review, Systematic review
CSF insulin-like growth factor-1 in infantile neuronal ceroid lipofusinosis
Riikonen R, Vanhanen S-L, Tyynelä J, Santavuori P, Turpeinen U, 2000, Neurology, 54, 1828-1832. A1 Journal article (refereed), original research
Decreased cerebrosbinal fluid levels of beta-phenylethylamine in patients with Rett syndrome
Satoi M, Matsuishi T, Yamada S, Yamashita Y, Ohtaki E, Mori K, Riikonen R, Kato H, Percy AK, 2000, Annals of neurology.
Markedly elevated nitrate/nitrite levels in the cerebrospinal fluid of children with progressive encephalopathy with edema, hypsarrhythmia, and optic atrophy (PEHO syndrome)
Vanhatalo S, Riikonen R, 2000, Epilepsia, 41, 6, 705-708. A1 Journal article (refereed), original research
Posttraumatic tremor and Arnold Chiari malformation: no sign of compression, but cure after surgical decompression
Vanhatalo S, Paetau R, Mustonen K, Hernesniemi J, Riikonen R, 2000, Movement disorders.
Steroids or vigabatrin in the treatment of infantile spasms?
Riikonen R, 2000, Pediatric neurology, 23, 5, 403-408. A1 Journal article (refereed), original research
Aivoinfarkti
Riikonen R, Pääkkönen L, 1999, Jääskeläinen J, Herrgård E, Komulainen J, Tikanoja T, Korppi M, Lastenlääkärin päivystyskirja, 39-41. D2 Article in a professional book (incl. an introduction by the editor)
Akuutti polyradikuliitti (Guillain-Barrén syndrooma)
Riikonen R, Pääkkönen L, 1999, Jääskeläinen J, Herrgård E, Komulainen J, Tikanoja T, Korppi M, Lastenlääkärin päivystyskirja, 37-38. D2 Article in a professional book (incl. an introduction by the editor)
Brain perfusion SPECT and MRI in foetal alcohol syndrome
Riikonen R, Salonen I, Partanen K, Verho S, 1999, Developmental medicine and child neurology, 41, 652-659. A1 Journal article (refereed), original research
Cerebrospinal nerve growth factor - a marker of asphyxia?
Riikonen RS, Korhonen LT, Lindholm DB, 1999, Pediatric neurology, 20, 137-141. A1 Journal article (refereed), original research
Infantiilispasmi-oireyhtymä
Riikonen R, Kiviranta T, Airaksinen E, 1999, Jääskeläinen J, Herrgård E, Komulainen J, Tikanoja T, Korppi M, Lastenlääkärin päivystyskirja, 34. D2 Article in a professional book (incl. an introduction by the editor)
Levels of cerebrospinal fluid nerve-growth factor differ in infantile autism and Rett syndrome
Riikonen R, Vanhala R, 1999, Developmental medicine and child neurology, 41, 148-152. A1 Journal article (refereed), original research
Low insulin-like growth factor (IGF-1) in the cerebrospinal fluid of children with progressive encephalopathy, hypsarrhythmia, and optic atrophy (PEHO) syndrome and cerebellar degeneration
Riikonen R, Somer M, Turpeinen U, 1999, Epilepsia, 40, 11, 1642-1648. A1 Journal article (refereed), original research
Brain derived neurotrophic factor is increased in cerebrospinal fluid of children suffering from asphyxia
Korhonen L, Riikonen R, Nawa H, Lindholm D, 1998, Neuroscience letters, 240, 151-154. A1 Journal article (refereed), original research
Neurotrophic factors in cerebrospinal fluid and serum of patients with Rett syndrome
Vanhala R, Korhonen L, Mikelsaar M, Lindholm D, Riikonen R, 1998, Journal of child neurology, 13, 429-433. A1 Journal article (refereed), original research
Overstimulation of nerve growth factors in postinfectious and autoimmune diseases
Riikonen RS, Söderström S, Korhonen LT, Lindholm DB, 1998, Pediatric neurology, 18, 231-235. A1 Journal article (refereed), original research
Pons tumour behind a phenotypic Rett syndrome presentation
Vanhala R, Gaily E, Paetau A, Riikonen R, 1998, Developmental medicine and child neurology, 40, 836-839. A1 Journal article (refereed), original research
Resistance to activated protein C (APC) in childhood hydrocephalus
Riikonen R, Kekomäki R, 1998, Thrombosis and haemostasis.
Infantiilispasmipotilaiden ennuste on oletettua parempi
Riikonen R, 1997, Lääkärilehti, 52, 13, 1549-1551. D1 Article in a trade journal
West syndrome: Cerebrospinal fluid nerve growth factor and effect of ACTH
Riikonen RS, Söderström S, Vanhala R, Ebendal T, Lindholm DB, 1997, Pediatric neurology, 17, 3, 224-229. A1 Journal article (refereed), original research

University of Eastern Finland Joensuu, Kuopio © University of Eastern Finland

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Raili Riikonen

Biochemical mechanisms in pathogenesis of infantile epileptic spasm syndrome

Could prevention of infantile spasms have been possible in a historical cohort of 31 tuberous sclerosis patients?

Insulin-Like Growth Factors in the Pathogenesis and Treatment of Neurological Disorders in Children

Teleneurology based management of Infantile spasms during COVID-19 pandemic: a consensus report by the South Asia Allied West Syndrome Research Group

18q12.3-q21.1 Microdeletion Detected in the Prenatally Alcohol-Exposed Dizygotic Twin With Discordant Fetal Alcohol Syndrome Phenotype

ACTH treatment of infantile spasms: Low-moderate vs high dose, natural vs synthetic ACTH. A retrospective study

Infantile Spasms: Outcome in Clinical Studies

Management practices for West syndrome in South Asia: A survey study and meta-analysis

Rett Syndrome: Search for Prognostic Factors

Is adrenocorticotropic hormone (ACTH) therapy loaded with severe side effects? Do not use synthetic ACTH at the same dosages as "natural" ACTH

CSF nerve growth factor (ß-NGF) is increased but CSF insulin-like growth factor-(IGF-1) is normal in children with tuberous sclerosis and infantile spasms

Insulin-Like Growth Factors in the Pathogenesis of Neurological Diseases in Children

Combination therapy for treatment of infantile spasms

Long-term mortality of patients with West syndrome

Treatment of autistic spectrum disorder with insulin-like growth factors

WONOEP appraisal: Molecular and cellular biomarkers for epilepsy

Does vigabatrin treatment for infantile spasms cause visual field defects? An international multicentre study

High-Lights of Epilepsy 2015

Infantile spasms and 15q11.2q13.1 chromosome duplication in two successive generations

Long-term outcome in children with infantile spasms treated with vigabatrin: A cohort of 180 patients

Long-term outcome in pyridoxine-responsive infantile epilepsy

Psychological distress of children with early-onset type 1 diabetes and their mothers' well-being

Serotonin and dopamine transporter binding in children with autism determined by SPECT

Neurotrophic factors in the pathenogenesis of neurological disorders with mental retardation in children

Nosological aspects of West syndrome

Cerebrospinal fluid insulin-like growth factors IGF-1 and IGF-2 in infantile autism

Childhood convulsive status epilepticus

Insulin-like growth factor delivery across the blood-brain barrier

Therapy and outcome of infants with infantile spasms

Analysis of four neuroligin genes as candidates for autism

Cerebrospinal fluid insulin-like growth factor 1 is low in acute and chronic white-matter diseases of children

Deep serotonergic and dopaminergic structures in fetal alcoholic syndrome: A study with nor-beeta-CIT-single-photon emission computed tomography and magnetic resonance imaging volumetry

The latest on infantile spasms

Cerebrospinal fluid insulin-like growth factor (IGF-1) and insulin-like growth factor binding protein (IGFBP-2) in children with acute lymphoblastic leukemia

Cerebrospinal fluid insulin-like growth factor-1, insulin growth factor binding protein-2 or nitric oxide are not increased in MS or ALS

Comparison of regional cerebral perfusion, EEG and cognitive functions in type 1 diabetic children with and without severe hypoglycaemia

Infantile spasms: Therapy and outcome

Lasten päänsärky

Neurocognitive functioning in children with type-1 diabetes with and without episodes of severe hypoglycaemia

Neurotrophic factors in the pathogenesis of Rett syndrome

Vertebral artery insufficiency as a possible mechanism for sudden infant death - in vivo evidence does not support findings from postmortem studies

Diabetesta sairastavat lapset ja oppimisvaikeudet

ACTH therapy of West syndrome: Finnish views

Epidemiological data of West syndrome in Finland

Long-term outcome of patients with West syndrome

Low levels of insulin-like growth factor-I in cerebrospinal fluid in children with autism

MECP2 gene analysis in classical Rett syndrome and in patients with Rett-like features

Neurotrophic factors in the pathogenesis of Rett syndrome

Nitric oxide metabolites, nitrates and nitrites in the cerebrospinal fluid in children with west syndrome

Reversed visual field constrictions in children after vigabatrin withdrawal-true retinal recovery or improved test performance only?

The PEHO syndrome

CSF insulin-like growth factor-1 in infantile neuronal ceroid lipofusinosis

Decreased cerebrosbinal fluid levels of beta-phenylethylamine in patients with Rett syndrome

Markedly elevated nitrate/nitrite levels in the cerebrospinal fluid of children with progressive encephalopathy with edema, hypsarrhythmia, and optic atrophy (PEHO syndrome)

Posttraumatic tremor and Arnold Chiari malformation: no sign of compression, but cure after surgical decompression

Steroids or vigabatrin in the treatment of infantile spasms?

Aivoinfarkti

Akuutti polyradikuliitti (Guillain-Barrén syndrooma)

Brain perfusion SPECT and MRI in foetal alcohol syndrome

Cerebrospinal nerve growth factor - a marker of asphyxia?

Infantiilispasmi-oireyhtymä

Levels of cerebrospinal fluid nerve-growth factor differ in infantile autism and Rett syndrome

Low insulin-like growth factor (IGF-1) in the cerebrospinal fluid of children with progressive encephalopathy, hypsarrhythmia, and optic atrophy (PEHO) syndrome and cerebellar degeneration

Brain derived neurotrophic factor is increased in cerebrospinal fluid of children suffering from asphyxia

Neurotrophic factors in cerebrospinal fluid and serum of patients with Rett syndrome

Overstimulation of nerve growth factors in postinfectious and autoimmune diseases

Pons tumour behind a phenotypic Rett syndrome presentation

Resistance to activated protein C (APC) in childhood hydrocephalus

Infantiilispasmipotilaiden ennuste on oletettua parempi

West syndrome: Cerebrospinal fluid nerve growth factor and effect of ACTH