Riikka Lampinen - UEFConnect

Refine your search

Information Publications

My research interest is to study the role of mitochondrial dysfunction in Alzheimer’s disease with patient-derived cellular model.

Research groups

Cellular Neurobiology 01.01.2017 -

Keywords

Alzheimer's disease astrocytes brain health environmental factors mild cognitive impairment mitochondria olfactory mucosal cells sense of smell

Publications

19/19 items

Traffic-related ultrafine particles influence gene regulation in olfactory mucosa cells altering PI3K/AKT signaling
Mussalo, Laura; Afonin, Alexey M.; Zavodna, Tana; Krejcik, Zdenek; Honkova, Katerina; Fayad, Claire; Shahbaz, Muhammad Ali; Kalapudas, Juho; Penttilä, Elina; Löppönen, Heikki; Koivisto, Anne M; Malm, Tarja; Topinka, Jan; Jalava, Pasi; Lampinen, Riikka; Kanninen, Katja M, 2025, Environment international, 199, 109484. A1 Journal article (refereed), original research
A technological comparison of freeze-dried poly-ɛ-caprolactone (PCL) and poly (lactic-co-glycolic acid) (PLGA) nanoparticles loaded with clozapine for nose-to-brain delivery
Lombardo, Rosamaria; Ruponen, Marika; Rautio, Jarkko; Lampinen, Riikka; Kanninen, Katja M.; Koivisto, Anne M.; Penttilä, Elina; Löppönen, Heikki; Demartis, Sara; Giunchedi, Paolo; Rassu, Giovanna; Fragalà, Maria Elena; Pignatello, Rosario, 2024, Journal of drug delivery science and technology, 93, 105419. A1 Journal article (refereed), original research
Exposure to urban particulate matter alters responses of olfactory mucosal cells to SARS-CoV-2 infection
Shahbaz, Muhammad Ali; Kuivanen, Suvi; Mussalo, Laura; Afonin, Alexey M; Kumari, Kajal; Behzadpour, Donya; Kalapudas, Juho; Koivisto, Anne M; Penttilä, Elina; Löppönen, Heikki; Jalava, Pasi; Vapalahti, Olli; Balistreri, Giuseppe; Lampinen, Riikka; Kanninen, Katja M, 2024, Environmental research, 249, 118451. A1 Journal article (refereed), original research
Traffic-related ultrafine particles impair mitochondrial functions in human olfactory mucosa cells – Implications for Alzheimer's disease
Mussalo, Laura; Lampinen, Riikka; Avesani, Simone; Závodná, Táňa; Krejčík, Zdeněk; Kalapudas, Juho; Penttilä, Elina; Löppönen, Heikki; Koivisto, Anne M; Malm, Tarja; Topinka, Jan; Giugno, Rosalba; Jalava, Pasi; Kanninen, Katja M, 2024, Redox biology, 75, 103272. A1 Journal article (refereed), original research
Upregulation of Integrin beta-3 in astrocytes upon Alzheimer's disease progression in the 5xFAD mouse model
Ivanova, Mariia; Belaya, Irina; Kucháriková, Nina; de Sousa Maciel, Izaque; Saveleva, Liudmila; Alatalo, Arto; Juvonen, Ilona; Thind, Navjot; Andrès, Clarisse; Lampinen, Riikka; Chew, Sweelin; Kanninen, Katja M, 2024, Neurobiology of disease, 191, 106410. A1 Journal article (refereed), original research
Development of Lyophilised Eudragit® Retard Nanoparticles for the Sustained Release of Clozapine via Intranasal Administration
Lombardo, Rosamaria; Ruponen, Marika; Rautio, Jarkko; Ghelardini, Carla; Di Cesare Mannelli, Lorenzo; Calosi, Laura; Bani, Daniele; Lampinen, Riikka; Kanninen, Katja M.; Koivisto, Anne M; Penttilä, Elina; Löppönen, Heikki; Pignatello, Rosario, 2023, Pharmaceutics, 15, 5, 1554. A1 Journal article (refereed), original research
Emissions from modern engines induce distinct effects in human olfactory mucosa cells, depending on fuel and aftertreatment
Mussalo, Laura; Avesani, Simone; Shahbaz, Muhammad Ali; Zavodna, Tana; Saveleva, Liudmila; Järvinen, Anssi; Lampinen, Riikka; Belaya, Irina; Krejcik, Zdenek; Ivanova, Mariia; Hakkarainen, Henri; Kalapudas, Juho; Penttilä, Elina; Löppönen, Heikki; Koivisto, Anne M; Malm, Tarja; Topinka, Jan; Giugno, Rosalba; Aakko-Saksa, Päivi; Chew, Sweelin; Rönkkö, Topi; Jalava, Pasi; Kanninen, Katja M, 2023, Science of the total environment, 905, 167038. A1 Journal article (refereed), original research
Human-derived air–liquid interface cultures decipher Alzheimer’s disease–SARS-CoV-2 crosstalk in the olfactory mucosa
Shahbaz, Muhammad Ali; Kuivanen, Suvi; Lampinen, Riikka; Mussalo, Laura; Hron, Tomáš; Závodná, Táňa; Ojha, Ravi; Krejčík, Zdeněk; Saveleva, Liudmila; Tahir, Numan Ahmad; Kalapudas, Juho; Koivisto, Anne M; Penttilä, Elina; Löppönen, Heikki; Singh, Prateek; Topinka, Jan; Vapalahti, Olli; Chew, Sweelin; Balistreri, Giuseppe; Kanninen, Katja M, 2023, Journal of neuroinflammation, 20, 1, 299. A1 Journal article (refereed), original research
An Alzheimer’s Disease Patient-Derived Olfactory Stem Cell Model Identifies Gene Expression Changes Associated with Cognition
Rantanen, Laura M.; Bitar, Maina; Lampinen, Riikka; Stewart, Romal; Quek, Hazel; Oikari, Lotta E.; Cunί-Lόpez, Carla; Sutharsan, Ratneswary; Thillaiyampalam, Gayathri; Iqbal, Jamila; Russell, Daniel; Penttilä, Elina; Löppönen, Heikki; Lehtola, Juha-Matti; Saari, Toni; Hannonen, Sanna; Koivisto, Anne M.; Haupt, Larisa M.; Mackay-Sim, Alan; Cristino, Alexandre S.; Kanninen, Katja M.; White, Anthony R., 2022, Cells, 11, 20, 3258. A1 Journal article (refereed), original research
Biometal Dyshomeostasis in Olfactory Mucosa of Alzheimer’s Disease Patients
Lampinen, Riikka; Górová, Veronika; Avesani, Simone; Liddell, Jeffrey R; Penttilä, Elina; Závodná, Táňa; Krejčík, Zdeněk; Lehtola, Juha-Matti; Saari, Toni; Kalapudas, Juho; Hannonen, Sanna; Löppönen, Heikki; Topinka, Jan; Koivisto, Anne M; White, Anthony R; Giugno, Rosalba; Kanninen, Katja M, 2022, International journal of molecular sciences, 23, 8, 4123. A1 Journal article (refereed), original research
Mitochondrial dysfunction in non-neuronal cells in Alzheimer’s disease
Lampinen, Riikka, 2022, Publications of the University of Eastern Finland. Dissertations in Health Sciences. G5 Doctoral dissertation (article)
Neuron-astrocyte transmitophagy is altered in Alzheimer's disease
Lampinen, Riikka; Belaya, Irina; Saveleva, Liudmila; Liddell, Jeffrey R; Rait, Dzhessi; Huuskonen, Mikko T; Giniatullina, Raisa; Sorvari, Annika; Soppela, Liisi; Mikhailov, Nikita; Boccuni, Isabella; Giniatullin, Rashid; Cruz-Haces, Marcela; Konovalova, Julia; Koskuvi, Marja; Domanskyi, Andrii; Hämäläinen, Riikka H; Goldsteins, Gundars; Koistinaho, Jari; Malm, Tarja; Chew, Sweelin; Rilla, Kirsi; White, Anthony R; Marsh-Armstrong, Nicholas; Kanninen, Katja M, 2022, Neurobiology of disease, 170, 105753. A1 Journal article (refereed), original research
Single-Cell RNA-Seq Analysis of Olfactory Mucosal Cells of Alzheimer’s Disease Patients
Lampinen, Riikka; Fazaludeen, Mohammad Feroze; Avesani, Simone; Örd, Tiit; Penttilä, Elina; Lehtola, Juha-Matti; Saari, Toni; Hannonen, Sanna; Saveleva, Liudmila; Kaartinen, Emma; Fernández Acosta, Francisco; Cruz-Haces, Marcela; Löppönen, Heikki; Mackay-Sim, Alan; Kaikkonen, Minna U; Koivisto, Anne M; Malm, Tarja; White, Anthony R; Giugno, Rosalba; Chew, Sweelin; Kanninen, Katja M, 2022, Cells, 11, 4, 676. A1 Journal article (refereed), original research
Olfactory cell cultures to investigate health effects of air pollution exposure: implications for neurodegeneration
Kanninen, KM; Lampinen, R; Rantanen, LM; Odendaal, L; Jalava, P; Chew, S; White, AR, 2020, Neurochemistry international, 136, 104729, . A2 Review article, Literature review, Systematic review
Urban air particulate matter induces mitochondrial dysfunction in human olfactory mucosal cells
Chew, Sweelin; Lampinen, Riikka; Saveleva, Liudmila; Korhonen, Paula; Mikhailov, Nikita; Grubman, Alexandra; Polo, Jose M; Wilson, Trevor; Komppula, Mika; Rönkkö, Teemu; Gu, Cheng; Mackay-Sim, Alan; Malm, Tarja; White, Anthony R; Jalava, Pasi; Kanninen, Katja M, 2020, Particle and fibre toxicology, 17, 1, 18, . A1 Journal article (refereed), original research
Mitochondrial Function in Alzheimer's Disease: Focus on Astrocytes
Lampinen, Riikka; Belaya, Irina; Boccuni, Isabella; Malm, Tarja; Kanninen, Katja M, 2018, Gentile, Maria Teresa, Astrocyte: Physiology and Pathology, 139-162. A3 Book section, Chapters in research books
PPARß/DELTA-agonist GW0742 ameliorates dysfunction in fatty acid oxidation in PSEN1deltaE9 astrocytes
Konttinen, H; Gureviciene, I; Oksanen, M; Grubman, A; Loppi, S; Huuskonen, MT; Korhonen, P; Lampinen, R; Keuters, M; Belaya, I; Tanila, H; Kanninen, KM; Goldsteins, G; Landreth, G; Koistinaho, J; Malm, T, 2018, Glia, 2019; 67, 1, 146-159, . A1 Journal article (refereed), original research
Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration
Abdalkader, Moataz; Lampinen, Riikka; Kanninen, Katja M; Malm, Tarja M; Liddell, Jeffrey R, 2018, Frontiers in neuroscience, 12, 466, . A2 Review article, Literature review, Systematic review
Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping
Lempiäinen Joanna K, Niskanen Einari A, Vuoti Kaisa-Mari, Lampinen Riikka E, Göös Helka, Varjosalo Markku, Palvimo Jorma J, 2017, Molecular and cellular proteomics, 16, 8, 1462-1474, . A1 Journal article (refereed), original research