I’m a philosopher and cognitive scientist. My current research focuses on systems science. My favorite part is the thrill of exploring the foundational aspects.
I unite infodynamics, control theory, causal analysis, and modeling to understand how the multiscale of complex adaptive (dynamical) systems emerges. Another goal of my research is to understand how structures formed by functional relations in a system, such as geometrically driven interactions that are inspired by neural networks.
The potential outcome of my research is to improve geometric model solutions, supervise scientific experiments, and highlight the importance of model solutions in considering operational propositions at the geoeconomic level of a system.
Additionally, I am interested in how formal methods and measurements based on cognitive dynamics can be used to acquire both the phenomenological level and content of natural language expressions.
I am conducting doctoral research in the field of guidance, focusing on the agency and capabilities in educational and career pathways for educated adults who have migrated to Finland and are enrolled in Finnish-language programs at universities of applied sciences.
In parallel with my doctoral research, I work as a lecturer in social services at a university of applied sciences. Additionally, I work as a professional supervisor, employing a psychodynamic-systemic theoretical framework.
The Cancer Cell Plasticity research group investigates how prostate cancer cells adopt stem-like, neuroplastic, and neuroendocrine states to drive therapy resistance and disease progression. The group studies how cancer cells transition between cellular states in response to both therapeutic pressure and signals from the tumor microenvironment. These include immune cell–derived factors, neural and neuroendocrine-associated programs, and mechanical cues such as extracellular matrix (ECM) stiffness, which actively regulate cancer cell behavior. The research integrates advanced imaging with functional genomics and epigenomics to capture dynamic changes in chromatin state and gene regulation. Genome-wide approaches (RNA-seq, ATAC-seq, ChIP-seq) are combined with live-cell high-content imaging, drug screening, and patient-derived models, including organoids and liquid biopsies. Zebrafish metastasis models are further used to study cancer cell dissemination and plasticity in vivo.
Key intrinsic regulators of plasticity have been identified, including transcription factors such as SIX2, which drive stem-like and androgen receptor–independent states through chromatin reprogramming. Key plasticity-associated effectors such as DPYSL5 supports neuroplasticity-associated phenotypes and antiandrogen resistance. In addition, DNA repair pathways, including the Fanconi anemia pathway (FANCI), support therapy resistance. Recent work demonstrates that ECM stiffness directly regulates chromatin accessibility and androgen receptor signaling, with stiff matrices promoting aggressive transcriptional programs associated with poor clinical outcome.
The overall goal is to identify novel therapeutic targets and biomarkers and to develop strategies to prevent or reverse treatment resistance in advanced prostate cancer.
Find Ketola Lab pages: https://uefconnect.uef.fi/en/group/cancer-cell-plasticity-ketola-lab/
My research focuses particularly on the guidance offered in schools and educational institutions and the implementation of the principle of the whole school approach to guidance. In addition to the context of general upper secondary school education, my expertise includes theoretical and methodological discussions of agency and guidance.
Scientific research in mechanistic and molecular toxicology, supervision of PhD studies, teaching in basic and advanced courses in toxicology
I am an early stage researcher, nutritionist and expert of food sciences. I currently work at the Stop Diabetes (StopDia) project in the Department of Clinical Nutrition in Kuopio. The StopDia study was set to create and implement evidence-based and digitally supported strategies for the prevention of type 2 diabetes at population level in three regions in Finland. It is funded by the Strategic Research Council and lasts until year 2019. I take care of practical issues of the StopDia randomized controlled trial and handle the RCT data.
I am interested in eating behavior and eating competence of the StopDia study participants, who are at increased risk for type 2 diabetes. With my study I hope to enhance knowledge on eating-related behavior and it’s association with obesity and type 2 diabetes. My goal is to find more efficient ways to make long-lasting healthy lifestyle changes and to conduct effective lifestyle interventions in healthcare and thus, preventing type 2 diabetes.
I’d like to build a research network. I am also active in social media and write nutrition-related blog posts.
I am a PhD researcher in nutrition science, a licensed dietitian and an expert in food science. I am currently working on the Kuopio campus in the Unit of Public Health and Clinical Nutrition in the Stop Diabetes (StopDia) project. The goal of the StopDia study was to create and implement ways to prevent type 2 diabetes in Finland based on scientific evidence and utilize digital tools. The study was funded by the Academy of Finland, Strategic Research. I take care of the practical matters of the randomized controlled trial StopDia, communication and analyse data. I also work in the T2D-Data project, which aims to find out who will benefit from using the BitHabit app in terms of type 2 diabetes prevention.
I also work as a nutrition expert in the national FOODNUTRI project, where we develop a measure of diet quality, the Healthy Diet Index, as a digital app for health promotion and health care services. The goal of the Healthy Diet Index app is to improve the effectiveness of nutritional counselling.
In my dissertation, I study the quality of the diet, the Healthy Diet Index, and eating behavior, more specifically the Satter Eating competence, and their connection to risk factors for type 2 diabetes in the StopDia data. With my research, I hope to increase knowledge on eating-related behavior and its connection to obesity and type 2 diabetes. My goal is to find more effective ways to make long-term health-promoting lifestyle changes, implement effective lifestyle interventions in healthcare and municipalities, and thereby prevent type 2 diabetes.
I would like to build my research network. I am also active on Twitter and I like to participate in nutrition communication.
Dr. K. Tamarov obtained his Specialist degree in Physics in 2013 from M.V. Lomonosov Moscow State University (MSU). After that he proceeded his studies in joint Ph.D. program in MSU and University of Eastern Finland (UEF) and received his Ph.D. degree in Applied Physics with distinction at UEF in 2017. Since then he works as a postdoctoral researcher at Department of Applied Physics, UEF.
His current research interests include:
• Metal-assisted catalytic etching of Si powders and its recently discovered low-load form.
• Regenerative electroless etching of Si powders and wafers to produce photoluminescent Si particles at large scale.
• Physical and chemical mechanisms of metal-assisted catalytic etching, regenerative electroless etching and electrochemical anodization.
• Hyperpolarization of Si and application of hyperpolarized Si nanoparticles for magnetic resonance imaging.
I investigate how growth factors regulating lymphatic development influence the progression of cardiometabolic diseases, with a particular focus on metabolic dysfunction–associated steatotic liver disease (MASLD) and liver recovery capacity. In addition to my research work, I coordinate the Cardiovascular Diseases Research Community (CVD RC).
Research focuses on corporate sustainability reporting and the use of sustainability information and reporting practices in strategic decision-making and management.
Prodrug expert and group leader (Docent/Adjunct Professor, Ph.D.), who is interested in drug targeting, e.g. into the brain and within the brain, but also into other tissues and cell types by utilizing endogenous transporter proteins. Read more about our activities from the UEF Connect group site, our official websites (WordPress) and/or our Blog (links above and behind the research group introduction).
