Suvi Linna-Kuosmanen - UEFConnect

Refine your search

Information Publications

Research groups

Molecular Physiology 01.01.2009 -

Publications

19/19 items

Genetics, transcriptomics, metagenomics, and metabolomics in the pathogenesis and prediction of atrial fibrillation
Linna-Kuosmanen, Suvi; Vuori, Matti; Kiviniemi, Tuomas; Palmu, Joonatan; Niiranen, Teemu. 2024. European heart journal supplements. 26: iv33-iv40 A1 Journal article (refereed), original research
Integrative multi-omics profiling in human decedents receiving pig heart xenografts
Schmauch, Eloi; Piening, Brian; Mohebnasab, Maedeh; Xia, Bo; Zhu, Chenchen; Stern, Jeffrey; Zhang, Weimin; Dowdell, Alexa K; Kim, Jacqueline I; Andrijevic, David; Khalil, Karen; Jaffe, Ian S; Loza, Bao Li; Gragert, Loren; Camellato, Brendan R; Oliveira, Michelli F; O’Brien, Darragh P; Chen, Han M; Weldon, Elaina; Gao, Hui; Gandla, Divya; Chang, Andrew; Bhatt, Riyana; Gao, Sarah; Lin, Xiangping; Reddy, Kriyana P; Kagermazova, Larisa; Habara, Alawi H; Widawsky, Sophie; Liang, Feng Xia; Sall, Josep. 2024. Nature medicine. 30: 1448-1460 A1 Journal article (refereed), original research
Targeting IL-1 controls refractory pityriasis rubra pilaris
Schmauch, Eloi; Severin, Yannik; Xing, Xianying; Mangold, Aaron; Conrad, Curdin; Johannsen, Pål; Kahlenberg, J Michelle; Mellett, Mark; Navarini, Alexander; Nobbe, Stefan; Sarkar, Mrinal K; Satyam, Abhigyan; Tsoi, Lam C; French, Lars E; Nilsson, Jakob; Linna-Kuosmanen, Suvi; Kaikkonen, Minna U; Snijder, Berend; Kellis, Manolis; Gudjonsson, Johann E.; Tsokos, George C; Contassot, Emmanuel; Kolios, Antonios GA. 2024. Science advances. 10: . eado2365 A1 Journal article (refereed), original research
Transcriptomic and spatial dissection of human ex vivo right atrial tissue reveals proinflammatory microvascular changes in ischemic heart disease
Linna-Kuosmanen, Suvi; Schmauch, Eloi; Galani, Kyriakitsa; Ojanen, Johannes; Boix, Carles A; Örd, Tiit; Toropainen, Anu; Singha, Prosanta K; Moreau, Pierre R; Harju, Kristiina; Blazeski, Adriana; Segerstolpe, Åsa; Lahtinen, Veikko; Hou, Lei; Kang, Kai; Meibalan, Elamaran; Agudelo, Leandro Z; Kokki, Hannu; Halonen, Jari; Jalkanen, Juho; Gunn, Jarmo; MacRae, Calum A; Hollmén, Maija; Hartikainen, Juha EK; Kaikkonen, Minna U; García-Cardeña, Guillermo; Tavi, Pasi; Kiviniemi, Tuomas; Kellis, Manolis. 2024. Cell reports medicine. 5: . 101556 A1 Journal article (refereed), original research
Genomic approaches to identify and investigate genes associated with atrial fibrillation and heart failure susceptibility
Patel, Kush Ketan; Venkatesan, Cynthia; Abdelhalim, Habiba; Zeeshan, Saman; Arima, Yuichiro; Linna-Kuosmanen, Suvi; Ahmed, Zeeshan. 2023. Human genomics. 17: . 47 A2 Review article, Literature review, Systematic review
NRF2 is a key regulator of endothelial microRNA expression under proatherogenic stimuli
Linna-Kuosmanen, Suvi; Bosch, Vanesa Tomas; Moreau, Pierre R; Bouvy-Liivrand, Maria; Niskanen, Henri; Kansanen, Emilia; Kivelä, Annukka; Hartikainen, Juha; Hippeläinen, Mikko; Kokki, Hannu; Tavi, Pasi; Levonen, Anna-Liisa; Kaikkonen, Minna U. 2021. Cardiovascular research. 117: 1339-1357 A1 Journal article (refereed), original research
Profiling of Primary and Mature miRNA Expression in Atherosclerosis Associated Cell Types
Moreau, PR; Tomas Bosch, V; Bouvy-Liivrand,M; Õunap, K; Örd, T; Pulkkinen, HH; Pölönen, P; Heinäniemi, M; Ylä-Herttuala, S; Laakkonen, JP; Linna-Kuosmanen, S; Kaikkonen, MU. 2021. Arteriosclerosis, thrombosis, and vascular biology. 41: 2149-2167 A1 Journal article (refereed), original research
Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma
Pölönen, P; Jawahar Deen, A; Leinonen, HM; Jyrkkänen, HK; Kuosmanen, S; Mononen, M; Jain, A; Tuomainen, T; Pasonen-Seppänen, S; Hartikainen, JM; Mannermaa, A; Nykter, M; Tavi, P; Johansen, T; Heinäniemi, M; Levonen, AL. 2019. Oncogene. 38: 7473-7490 A1 Journal article (refereed), original research
MicroRNAs mediate the senescence-associated decline of NRF2 in endothelial cells
Kuosmanen, SM; Sihvola, V; Kansanen, E; Kaikkonen, MU; Levonen, AL. 2018. Redox biology. 18: 77-83 A1 Journal article (refereed), original research
MicroRNA Profiling Reveals Distinct Profiles for Tissue-Derived and Cultured Endothelial Cells
Kuosmanen Suvi M, Kansanen Emilia, Sihvola Virve, Levonen Anna-Liisa. 2017. Scientific reports. 7: 10943 A1 Journal article (refereed), original research
MicroRNAs in endothelial aging and atherosclerosis
Kuosmanen Suvi. 2017. Publications of the University of Eastern Finland. Dissertations in Health Sciences G5 Doctoral dissertation (article)
NRF2 regulates endothelial glycolysis and proliferation with miR-93 and mediates the effects of oxidized phospholipids on endothelial activation
Kuosmanen SM, Kansanen E, Kaikkonen MU, Sihvola V, Pulkkinen K, Jyrkkänen H-K, Tuoresmäki P, Hartikainen J, Hippeläinen M, Kokko H, Tavi P, Heikkinen S, Levonen A-M. 2017. Nucleic acids research. 2018; 46: 1124-1138 A1 Journal article (refereed), original research
Nitro-Oleic Acid Regulates Endothelin Signaling in Human Endothelial Cells
Kansanen Emilia, Kuosmanen Suvi M, Ruotsalainen Anna-Kaisa, Hynynen Heidi, Levonen Anna-Liisa. 2017. Molecular pharmacology. 92: 481-490 A1 Journal article (refereed), original research
The Effects of Sequence Variation on Genome-wide NRF2 Binding - New Target Genes and Regulatory SNPs
Kuosmanen Suvi M, Viitala Sari, Laitinen Tuomo, Peräkylä Mikael, Pölönen Petri, Kansanen Emilia, Leinonen Hanna, Raju Suresh, Wienecke-Baldacchino Anke, Närvänen Ale, Poso Antti, Heinäniemi Merja, Heikkinen Sami, Levonen Anna-Liisa. 2016. Nucleic acids research. 44: 1760-1775 A1 Journal article (refereed), original research
MicroRNA profiling of pericardial fluid samples from patients with heart failure
Kuosmanen Suvi M, Hartikainen Juha, Hippeläinen Mikko, Kokki Hannu, Levonen Anna-Liisa, Tavi Pasi. 2015. PLoS ONE. 10: e0119646 A1 Journal article (refereed), original research
The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer
Kansanen Emilia, Kuosmanen Suvi M, Leinonen Hanna, Levonen Anna-Liisa. 2013. Redox biology. Volume 1, Issue 1, 2013: 45-49 A2 Review article, Literature review, Systematic review
Oxidative stress-regulated lentiviral TK/GCV gene therapy for lung cancer treatment
Leinonen HM, Ruotsalainen AK, Määttä AM, Laitinen HM, Kuosmanen SM, Kansanen E, Pikkarainen JT, Lappalainen JP, Samaranayake H, Lesch HP, Kaikkonen MU, Ylä-Herttuala S, Levonen AL. 2012. Cancer research. 2012 Oct 9. [Epub ahead of print]: - - A1 Journal article (refereed), original research
Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism
Kansanen Emilia, Bonacci Gustavo, Schopfer Francisco J, Kuosmanen Suvi M, Tong Kit I, Leinonen Hanna, Woodcock Steven R, Yamamoto Masayuk, Carlberg Carsten, Ylä-Herttuala Seppo, Freeman Bruce A, Levonen Anna-Liisa. 2011. Journal of biological chemistry. 286: 14019-14027 A1 Journal article (refereed), original research
Novel insights into the regulation of antioxidant-response-element-mediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2
Jyrkkänen HK, Kuosmanen S, Heinäniemi M, Laitinen H, Kansanen E, Mella-Aho E, Leinonen H, Ylä-Herttuala S, Levonen AL. 2011. Biochemical journal. : 167-74 A1 Journal article (refereed), original research