Teemu Natunen
University Lecturer
Institute of Biomedicine, School of Medicine, Faculty of Health Sciences
[email protected] | +358 50 387 1272
Publications
21/21 items-
Lithium chloride alters Tau phosphorylation, kinase activity, and Rho GTPase signaling in cell models
Hoffmann, Dorit; Ahola, Virpi; Huber, Nadine; Natunen, Teemu; Leskelä, Stina; Takalo, Mari; Martiskainen, Henna; Ballweg, Stephanie; Vorontsov, Egor; Selzer, Stefan; Kallio, Pekka; Pike, Ian; Sirviö, Jouni; Haapasalo, Annakaisa; Hiltunen, Mikko, 2026, Biomedicine and pharmacotherapy, 198, 119347. A1 Journal article (refereed), original research -
Mitigation of Acute Seizures and Neuropathology after Traumatic Brain Injury by Structure-Based Discovery-Identified Drugs
Kajevu, Natallie; Banuelos, Ivette; Andrade, Pedro; Hämäläinen, Elina; Sabatier, Laureano; Couyoupetrou, Manuel; Villalba, María Luisa; Gavernet, Luciana; Lipponen, Anssi; Natunen, Teemu; Puhakka, Noora; Hiltunen, Mikko; Talevi, Alan; Pitkänen, Asla, 2025, Journal of neurotrauma, 42, 15-16, 1433-1452. A1 Journal article (refereed), original research -
The protective PLCγ2-P522R variant mitigates Alzheimer’s disease-associated pathologies by enhancing beneficial microglial functions
Takalo, Mari; Jeskanen, Heli; Rolova, Taisia; Kervinen, Inka; Hellén, Marianna; Heikkinen, Sami; Koivisto, Hennariikka; Jokivarsi, Kimmo; Müller, Stephan A.; Koivumäki, Esa-Mikko; Mäkinen, Petra; Juopperi, Sini-Pauliina; Willman, Roosa-Maria; Sinisalo, Rosa; Hoffmann, Dorit; Jäntti, Henna; Peitz, Michael; Fließbach, Klaus; Kuulasmaa, Teemu; Natunen, Teemu; Kemppainen, Susanna; Poutiainen, Pekka; Leinonen, Ville; Malm, Tarja; Martiskainen, Henna; Ramirez, Alfredo; Haapasalo, Annakaisa; Lichtentha, 2025, Journal of neuroinflammation, 22, 1, 64. A1 Journal article (refereed), original research -
Three‐dimensional view of microglia—amyloid plaque interactions
Gotkiewicz, Maria; Capra, Janne; Miettinen, Pasi O; Natunen, Teemu; Tanila, Heikki, 2024, Glia, 73, 1, 196-209. A1 Journal article (refereed), original research -
Gene Expression Profile as a Predictor of Seizure Liability
Lipponen, Anssi; Kajevu, Natallie; Natunen, Teemu; Ciszek, Robert; Puhakka, Noora; Hiltunen, Mikko; Pitkänen, Asla, 2023, International journal of molecular sciences, 24, 4, 4116. A1 Journal article (refereed), original research -
Protective Alzheimer's disease-associated APP A673T variant predominantly decreases sAPPβ levels in cerebrospinal fluid and 2D/3D cell culture models
Wittrahm, Rebekka; Takalo, Mari; Kuulasmaa, Teemu; Mäkinen, Petra M; Mäkinen, Petri; Končarević, Saša; Fartzdinov, Vadim; Selzer, Stefan; Kokkola, Tarja; Antikainen, Leila; Martiskainen, Henna; Kemppainen, Susanna; Marttinen, Mikael; Jeskanen, Heli; Rostalski, Hannah; Rahunen, Eija; Kivipelto, Miia; Ngandu, Tiia; Natunen, Teemu; Lambert, Jean-Charles; Tanzi, Rudolph E; Kim, Doo Yeon; Rauramaa, Tuomas; Herukka, Sanna-Kaisa; Soininen, Hilkka; Laakso, Markku; Pike, Ian; Leinonen, Ville; Haapasalo,, 2023, Neurobiology of disease, 182, 106140. A1 Journal article (refereed), original research -
Treatment of Status Epilepticus after Traumatic Brain Injury Using an Antiseizure Drug Combined with a Tissue Recovery Enhancer Revealed by Systems Biology
Kajevu, Natallie; Lipponen, Anssi; Andrade, Pedro; Bañuelos, Ivette; Puhakka, Noora; Hämäläinen, Elina; Natunen, Teemu; Hiltunen, Mikko; Pitkänen, Asla, 2023, International journal of molecular sciences, 24, 18, 14049. A1 Journal article (refereed), original research -
Enhanced drug delivery by a prodrug approach effectively relieves neuroinflammation in mice
Montaser, Ahmed B.; Kuiri, Janita; Natunen, Teemu; Hruška, Pavel; Potěšil, David; Auriola, Seppo; Hiltunen, Mikko; Terasaki, Tetsuya; Lehtonen, Marko; Jalkanen, Aaro; Huttunen, Kristiina M, 2022, Life sciences, 310, 121088. A1 Journal article (refereed), original research -
Effects of Alzheimer's Disease-Associated Risk Loci on Cerebrospinal Fluid Biomarkers and Disease Progression: A Polygenic Risk Score Approach
Martiskainen Henna, Helisalmi Seppo, Viswanathan Jayashree, Kurki Mitja, Hall Anette, Herukka Sanna-Kaisa, Sarajärvi Timo, Natunen Teemu, Kurkinen Kaisa M.A., Huovinen Jaakko, Mäkinen Petra, Laitinen Marjo, Koivisto Anne M., Mattila Kari M., Lehtimäki Terho, Remes Anne M., Leinonen Ville, Haapasalo Annakaisa, Soininen Hilkka, Hiltunen Mikko, 2015, Journal of Alzheimer's disease, 43, 2, 565-573. A1 Journal article (refereed), original research -
Genetic Variation in delta-Opioid Receptor Associates with Increased ß- and gamma-Secretase Activity in the Late Stages of Alzheimer's Disease
Sarajärvi Timo, Marttinen Mikael, Natunen Teemu, Kauppinen Tarja, Mäkinen Petra, Helisalmi Seppo, Laitinen Marjo, Rauramaa Tuomas, Leinonen Ville, Petäjä-Repo Ulla, Soininen Hilkka, Haapasalo Annakaisa, Hiltunen Mikko, 2015, Journal of Alzheimer's disease, 48, 2, 507-516. A1 Journal article (refereed), original research