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Tuomo Rantanen

Tuomo Rantanen

Professor

Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences

[email protected] | +358 40 358 9905

Information Publications

Research groups

Gastroenterological surgery 01.01.2022 -

Publications

71/71 items

Epidural analgesia during esophagectomy and esophageal cancer prognosis: A population‐based nationwide study in Finland
Petäjäkangas, Pia H.; Helminen, Olli; Helmiö, Mika; Huhta, Heikki; Kallio, Raija; Koivukangas, Vesa; Kokkola, Arto; Laine, Simo; Lietzen, Elina; Meriläinen, Sanna; Pohjanen, Vesa‐Matti; Rantanen, Tuomo; Ristimäki, Ari; Räsänen, Jari V.; Saarnio, Juha; Sihvo, Eero; Toikkanen, Vesa; Tyrväinen, Tuula; Valtola, Antti; Kauppila, Joonas H.. 2025. Acta anaesthesiologica scandinavica. 69: . e70016 A1 Journal article (refereed), original research
Incidence trends of surgical complications after oesophagectomy for oesophageal cancer: a population-based, nationwide cohort study in Finland over 30 years
Sirviö, Ville E.J.; Räsänen, Jari V.; Helminen, Olli; Helmiö, Mika; Huhta, Heikki; Kallio, Raija; Koivukangas, Vesa; Kokkola, Arto; Laine, Simo; Lietzen, Elina; Meriläinen, Sanna; Pohjanen, Vesa-Matti; Rantanen, Tuomo; Ristimäki, Ari; Saarnio, Juha; Sihvo, Eero; Toikkanen, Vesa; Tyrväinen, Tuula; Uimonen, Mikko; Valtola, Antti; Kauppila, Joonas H.. 2025. World journal of surgical oncology. 23: 1-10 A1 Journal article (refereed), original research
Preoperative predictors of postoperative complications after gastrectomy for gastric cancer, a population-based study in Finland
Putila, Emilia; Helminen, Olli; Helmiö, Mika; Huhta, Heikki; Jalkanen, Aapo; Junttila, Anna; Kallio, Raija; Koivukangas, Vesa; Kokkola, Arto; Lietzen, Elina; Louhimo, Johanna; Meriläinen, Sanna; Pohjanen, Vesa Matti; Rantanen, Tuomo; Ristimäki, Ari; Räsänen, Jari V; Sihvo, Eero; Toikkanen, Vesa; Tyrväinen, Tuula; Valtola, Antti; Kauppila, Joonas H; on behalf of the FINEGO group. 2025. Ejso. 51: . 109682 A1 Journal article (refereed), original research
A randomized double-blind noninferiority clinical multicenter trial on oral moxifloxacin versus placebo in the outpatient treatment of uncomplicated acute appendicitis: APPAC IV study protocol
Lund, Heidi; Haijanen, Jussi; Suominen, Saku; Hurme, Saija; Sippola, Suvi; Rantanen, Tuomo; Rautio, Tero; Mattila, Anne; Pinta, Tarja; Nordstrom, Pia; Kossi, Jyrki; Ilves, Imre; Salminen, Paulina. 2024. Scandinavian journal of surgery. 114: 3-12 A1 Journal article (refereed), original research
Comparison of Postoperative Complications After Gastrectomy for Gastric Cancer with Antecolic Versus Retrocolic Reconstruction: A Population-Based Study
Junttila, Anna; Helminen, Olli; Helmiö, Mika; Huhta, Heikki; Jalkanen, Aapo; Kallio, Raija; Koivukangas, Vesa; Kokkola, Arto; Laine, Simo; Lietzen, Elina; Louhimo, Johanna; Meriläinen, Sanna; Pohjanen, Vesa Matti; Rantanen, Tuomo; Ristimäki, Ari; Räsänen, Jari V. Saarnio, Juha; Sihvo, Eero; Toikkanen, Vesa; Tyrväinen, Tuula; Valtola, Antti; Kauppila, Joonas H. 2024. Annals of surgical oncology. 31: 5263-5272 A1 Journal article (refereed), original research
Impact of Splenectomy on Long-term Outcomes after Gastrectomy for Gastric Cancer - a Population-based Study
Junttila, Anna; Helminen, Olli; Helmiö, Mika; Huhta, Heikki; Jalkanen, Aapo; Kallio, Raija; Koivukangas, Vesa; Kokkola, Arto; Laine, Simo; Lietzen, Elina; Louhimo, Johanna; Meriläinen, Sanna; Pohjanen, Vesa-Matti; Rantanen, Tuomo; Ristimäki, Ari; Räsänen, Jari V.; Saarnio, Juha; Sihvo, Eero; Toikkanen, Vesa; Tyrväinen, Tuula; Valtola, Antti; Kauppila, Joonas H; FINEGO group. 2024. Journal of gastrointestinal surgery. 28: 2090-2096 A1 Journal article (refereed), original research
Impact of an appendicolith and its characteristics on the severity of acute appendicitis
Sula, Sami; Paananen, Timo; Tammilehto, Ville; Hurme, Saija; Mattila, Anne; Rantanen, Tuomo; Rautio, Tero; Pinta, Tarja; Sippola, Suvi; Haijanen, Jussi M; Salminen, Paulina. 2024. BJS open. 8: A1 Journal article (refereed), original research
Intraoperative Bleeding Complications Leading to Blood Transfusions (BloTs) in 17,412 Cholecystectomies in Finland: A Study With Special Reference to Elderly Patients
Kivivuori, Antti; Lammi, Pekka; Eskelinen, Matti; Rantanen, Tuomo; Paajanen, Hannu; Pulkkinen, Jukka; Ukkonen, Mika. 2024. Anticancer research. 44: 4449-4456 A1 Journal article (refereed), original research
Postoperative Delayed Emptying after Total, Subtotal, or Distal Gastrectomy for Gastric Cancer - a Population-based Study
Junttila, Anna; Helminen, Olli; Helmiö, Mika; Huhta, Heikki; Jalkanen, Aapo; Kallio, Raija; Koivukangas, Vesa; Kokkola, Arto; Laine, Simo; Lietzen, Elina; Louhimo, Johanna; Meriläinen, Sanna; Pohjanen, Vesa-Matti; Rantanen, Tuomo; Ristimäki, Ari; Räsänen, Jari V; Saarnio, Juha; Sihvo, Eero; Toikkanen, Vesa; Tyrväinen, Tuula; Valtola, Antti; Kauppila, Joonas H; on behalf of the FINEGO group. 2024. Journal of gastrointestinal surgery. 28: 1083-1088 A1 Journal article (refereed), original research
Stapled vs handsewn anastomosis and anastomotic leaks in gastric cancer surgery—a population-based nationwide study in Finland
Kvist, Elina; Helminen, Olli; Helmiö, Mika; Huhta, Heikki; Jalkanen, Aapo; Junttila, Anna; Kallio, Raija; Koivukangas, Vesa; Kokkola, Arto; Laine, Simo; Lietzen, Elina; Louhimo, Johanna; Meriläinen, Sanna; Pohjanen, Vesa Matti; Rantanen, Tuomo; Ristimäki, Ari; Räsänen, Jari V; Saarnio, Juha; Sihvo, Eero; Toikkanen, Vesa; Tyrväinen, Tuula; Valtola, Antti; Kauppila, Joonas H; on behalf of the FINEGO group. 2024. Journal of gastrointestinal surgery. 28: 820-823 A1 Journal article (refereed), original research
Three-Year Outcomes of Oral Antibiotics vs Intravenous and Oral Antibiotics for Uncomplicated Acute Appendicitis
Selänne, Liisa; Haijanen, Jussi; Sippola, Suvi; Hurme, Saija; Rautio, Tero; Nordström, Pia; Rantanen, Tuomo; Pinta, Tarja; Ilves, Imre; Mattila, Anne; Rintala, Jukka; Marttila, Harri; Meriläinen, Sanna; Laukkarinen, Johanna; Sävelä, Eeva-Liisa; Paajanen, Hannu; Grönroos, Juha; Salminen, Paulina. 2024. JAMA surgery. 159: 727-735 A1 Journal article (refereed), original research
Five-year Survival after McKeown Compared to Ivor-Lewis Esophagectomy for Esophageal Cancer: A Population-based Nationwide Study in Finland
Junttila, Anna; Helminen, Olli; Helmio, Mika; Huhta, Heikki; Kallio, Raija; Koivukangas, Vesa; Kokkola, Arto; Laine, Simo; Lietzen, Elina; Merilainen, Sanna; Pohjanen, Vesa Matti; Rantanen, Tuomo; Ristimäki, Ari; Räsänen, Jari V; Saarnio, Juha; Sihvo, Eero; Toikkanen, Vesa; Tyrvainen, Tuula; Valtola, Antti; Kauppila, Joonas H. 2023. Annals of surgery. 277: 964-970 A1 Journal article (refereed), original research
Five-year follow-up of appendiceal neoplasm risk in periappendicular abscess in the Peri-Appendicitis Acuta Randomized Clinical Trial
Salminen, Roosa; Rautio, Tero; Nordstrom, Pia; Rantanen, Tuomo; Mallinen, Jari; Gronroos, Juha; Salminen, Paulina. 2023. Scandinavian journal of surgery. 112: 265-268 A1 Journal article (refereed), original research
Laparoscopic cholecystectomy versus antibiotic therapy for acute cholecystitis in patients over 75 years: Randomized clinical trial and retrospective cohort study
Kivivuori, Antti; Salminen, Paulina; Ukkonen, Mika; Ilves, Imre; Vihervaara, Hanna; Zalevskaja, Kristina; Pajari, Jenni; Paajanen, Hannu; Rantanen, Tuomo. 2023. Scandinavian journal of surgery. 114: 219-226 A1 Journal article (refereed), original research
Population-based nationwide incidence of complications after gastrectomy for gastric adenocarcinoma in Finland
Putila, Emilia; Helminen, Olli; Helmiö, Mika; Huhta, Heikki; Jalkanen, Aapo; Kallio, Raija; Koivukangas, Vesa; Kokkola, Arto; Laine, Simo; Lietzen, Elina; Louhimo, Johanna; Meriläinen, Sanna; Pohjanen, Vesa-Matti; Rantanen, Tuomo; Ristimäki, Ari; Räsänen, Jari V; Saarnio, Juha; Sihvo, Eero; Toikkanen, Vesa; Tyrväinen, Tuula; Valtola, Antti; Kauppila, Joonas H. 2023. BJS open. 7: . zrad101 A1 Journal article (refereed), original research
Postoperative Complications After Neoadjuvant Chemotherapy Versus Upfront Surgery in Gastric Adenocarcinoma: A Population-Based Nationwide Study in Finland
Putila, Emilia; Helminen, Olli; Helmiö, Mika; Huhta, Heikki; Jalkanen, Aapo; Kallio, Raija; Koivukangas, Vesa; Kokkola, Arto; Laine, Simo; Lietzen, Elina; Louhimo, Johanna; Meriläinen, Sanna; Pohjanen, Vesa-Matti; Rantanen, Tuomo; Junttila, Anna; Ristimäki, Ari; Räsänen, Jari V; Saarnio, Juha; Sihvo, Eero; Toikkanen, Vesa; Tyrväinen, Tuula; Valtola, Antti; Kauppila, Joonas H; the FINEGO Group. 2023. Annals of surgical oncology. 2024; 31: 2689-2698 A1 Journal article (refereed), original research
Preoperative Esophageal Stenting and 5-Year Survival in Patients Undergoing Esophagectomy for Esophageal Cancer: a Population-Based Nationwide Study from Finland
Helminen, Olli; Sihvo, Eero; Helmio, Mika; Huhta, Heikki; Kallio, Raija; Koivukangas, Vesa; Kokkola, Arto; Laine, Simo; Lietzen, Elina; Merilainen, Sanna; Pohjanen, Vesa-Matti; Rantanen, Tuomo; Ristimaki, Ari; Rasanen, Jari V; Saarnio, Juha; Toikkanen, Vesa; Tyrvainen, Tuula; Valtola, Antti; Kauppila, Joonas H. 2023. Journal of gastrointestinal surgery. 27: 1078-1088 A1 Journal article (refereed), original research
Wait-and-see strategy is justified after ERCP and endoscopic sphincterotomy in elderly patients with common biliary duct stones
Kivivuori, Antti; Mattila, Laura; Siiki, Antti; Laukkarinen, Johanna; Rantanen, Tuomo; Ukkonen, Mika. 2023. Journal of trauma and acute care surgery. 94: 443-447 A1 Journal article (refereed), original research
ASO Visual Abstract: Long-Term Survival after Transhiatal Compared with Transthoracic Esophagectomy—a Population-Based Nationwide Study in Finland
Junttila, Anna; Helminen, Olli; Helmiö, Mika; Huhta, Heikki; Kallio, Raija; Koivukangas, Vesa; Kokkola, Arto; Laine, Simo; Lietzen, Elina; Meriläinen, Sanna; Pohjanen, Vesa-Matti; Rantanen, Tuomo; Ristimäki, Ari; Räsänen, Jari V; Saarnio, Juha; Sihvo, Eero; Toikkanen, Vesa; Tyrväinen, Tuula; Valtola, Antti; Kauppila, Joonas H; the FINEGO group. 2022. Annals of surgical oncology abstract
Antibiotics versus placebo in adults with CT-confirmed uncomplicated acute appendicitis (APPAC III): randomized double-blind superiority trial
Salminen, Paulina; Sippola, Suvi; Haijanen, Jussi; Nordström, Pia; Rantanen, Tuomo; Rautio, Tero; Sallinen, Ville; Löyttyniemi, Eliisa; Hurme, Saija; Tammilehto, Ville; Laukkarinen, Johanna; Savolainen, Heini; Meriläinen, Sanna; Leppäniemi, Ari; Grönroos, Juha. 2022. British journal of surgery. 109: 503-509 A1 Journal article (refereed), original research
Long-Term Survival After Transhiatal Versus Transthoracic Esophagectomy: A Population-Based Nationwide Study in Finland
Junttila, Anna; Helminen, Olli; Helmiö, Mika; Huhta, Heikki; Kallio, Raija; Koivukangas, Vesa; Kokkola, Arto; Laine, Simo; Lietzen, Elina; Meriläinen, Sanna; Pohjanen, Vesa-Matti; Rantanen, Tuomo; Ristimäki, Ari; Räsänen, Jari V.; Saarnio, Juha; Sihvo, Eero; Toikkanen, Vesa; Tyrväinen, Tuula; Valtola, Antti; Kauppila, Joonas H.; on behalf of the FINEGO Group. 2022. Annals of surgical oncology. 29: 8159-8167 A1 Journal article (refereed), original research
Robotic versus hybrid assisted ventral hernia repair: a prospective one-year comparative study of clinical outcomes
Käkelä, Pirjo; Mustonen, Kirsi; Rantanen, Tuomo; Paajanen, Hannu. 2022. Acta chirurgica Belgica. [Published online: 04 May 2022]: 1-7 A1 Journal article (refereed), original research
The association between appendicitis severity and patient age with appendiceal neoplasm histology : a population-based study
Alajääski, Jenny; Lietzén, Elina; Grönroos, Juha M.; Mecklin, Jukka Pekka; Leppäniemi, Ari; Nordström, Pia; Rautio, Tero; Rantanen, Tuomo; Sand, Juhani; Paajanen, Hannu; Ollila, Helena; Salminen, Paulina. 2022. International journal of colorectal disease. 37: 1173-1180 A1 Journal article (refereed), original research
Discrimination between Pancreatic Cancer, Pancreatitis and Healthy Controls Using Urinary Polyamine Panel
Nissinen, Samuli I; Venäläinen, Markus; Kumpulainen, Pekka; Roine, Antti; Häkkinen, Merja R; Vepsäläinen, Jouko; Oksala, Niku; Rantanen, Tuomo. 2021. Cancer control. 29: 1-9 A1 Journal article (refereed), original research
Effect of Oral Moxifloxacin vs Intravenous Ertapenem Plus Oral Levofloxacin for Treatment of Uncomplicated Acute Appendicitis: The APPAC II Randomized Clinical Trial
Sippola, Suvi; Haijanen, Jussi; Grönroos, Juha; Rautio, Tero; Nordström, Pia; Rantanen, Tuomo; Pinta, Tarja; Ilves, Imre; Mattila, Anne; Rintala, Jukka; Löyttyniemi, Eliisa; Hurme, Saija; Tammilehto, Ville; Marttila, Harri; Meriläinen, Sanna; Laukkarinen, Johanna; Sävelä, Eeva-Liisa; Savolainen, Heini; Sippola, Tomi; Aarnio, Markku; Paajanen, Hanu; Salminen, Pauliina. 2021. JAMA : Journal of the American Medical Association. 325: 353-362 A1 Journal article (refereed), original research
Fatal complications after an interrupted gastric bypass operation in a patient with non-alcoholic fatty liver disease and massive obesity: a case report
Käkelä, Pirjo; Rantanen, Tuomo; Paajanen, Hannu; Virtanen, Kirsi A. 2021. Journal of surgical case reports. : rjab247 B1 Non-refereed journal articles
The Importance of Intestinal Length in Triglyceride Metabolism and in Predicting the Outcomes of Comorbidities in Laparoscopic Roux-en-Y Gastric Bypass-a Narrative Review
Käkelä, Pirjo; Rantanen, Tuomo; Virtanen, Kirsi A. 2021. Obesity surgery. 31: 3291-3295 A2 Review article, Literature review, Systematic review
Cohort profile: a nationwide population-based retrospective assessment of oesophageal cancer in the Finnish National Esophago-Gastric Cancer Cohort (FINEGO)
Söderström, Henna K; Räsänen, Jari; Saarnio, Juha; Toikkanen, Vesa; Tyrväinen, Tuula; Rantanen, Tuomo; Valtola, Antti; Ohtonen, Pasi; Pääaho, Minna; Kokkola, Arto; Kallio, Raija; Karttunen, Tuomo J; Pohjanen, Vesa-Matti; Ristimäki, Ari; Laine, Simo; Sihvo, Eero; Kauppila, Joonas H. 2020. BMJ open. 10: e039575 A1 Journal article (refereed), original research
Cohort profile: gastric cancer in the population-based, Finnish National Esophago-Gastric Cancer Cohort (FINEGO) Study
Kauppila, Joonas H; Ohtonen, Pasi; Rantanen, Tuomo; Tyrväinen, Tuula; Toikkanen, Vesa; Pääaho, Minna; Valtola, Antti; Räsänen, Jari; Kallio, Raija; Sihvo, Eero; Saarnio, Juha; Karttunen, Tuomo J; Pohjanen, Vesa-Matti; Ristimäki, Ari; Laine, Simo; Kokkola, Arto. 2020. BMJ open. 10: e039574 A1 Journal article (refereed), original research
Perioperative Changes in Hemoglobin Levels During Major Hepatopancreatic Surgery in Transfused and Non-Transfused Patients
Lammi, J P; Eskelinen, M; Tuimala, J; Selander, T; Saarnio, J; Rantanen, T. 2020. Scandinavian journal of surgery. 2021; 110: 407-413 A1 Journal article (refereed), original research
Prognostic role of radiological peritoneal cancer index in malignant peritoneal mesothelioma: national cohort study
Salo, Silja A S; Lantto, Eila; Robinson, Eric; Myllärniemi, Marjukka; Laaksonen, Sanna; Salo, Jarmo A; Rantanen, Tuomo; Ilonen, Ilkka. 2020. Scientific reports. 10: 13257 A1 Journal article (refereed), original research
Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis A Secondary Analysis of a Randomized Clinical Trial
Sippola, Suvi; Haijanen, Jussi; Viinikainen, Lauri; Grönroos, Juha; Paajanen, Hannu; Rautio, Tero; Nordström, Pia; Aarnio, Markku; Rantanen, Tuomo; Hurme, Saija; Mecklin, Jukka-Pekka; Sand, Juhani; Jartti, Airi; Salminen, Paulina. 2020. JAMA surgery. 155: 283-289 A1 Journal article (refereed), original research
Superior primary fascial closure rate and lower mortality after open abdomen using negative pressure wound therapy with continuous fascial traction.
Rasilainen, Suvi; Mentula, Panu; Salminen, Paulina; Koivukangas, Vesa; Hyöty, Marja; Mäntymäki, Leena-Maija; Pinta, Tarja; Haikonen, Jyrki; Rintala, Jukka; Rantanen, Tuomo; Strander, Tapani; Leppäniemi, Ari. 2020. Journal of trauma and acute care surgery. 89: 1136-1142 A1 Journal article (refereed), original research
Cost analysis of antibiotic therapy versus appendectomy for treatment of uncomplicated acute appendicitis: 5-year results of the APPAC randomized clinical trial
Haijanen, Jussi; Sippola, Suvi; Tuominen, Risto; Grönroos, Juha; Paajanen, Hannu; Rautio, Tero; Nordström, Pia; Aarnio, Markku; Rantanen, Tuomo; Hurme, Saija; Salminen, Paulina. 2019. PLoS ONE. 14: e0220202 A1 Journal article (refereed), original research
Detection of Pancreatic Cancer by Urine Volatile Organic Compound Analysis
Nissinen, SI; Roine, A; Hokkinen, L; Karjalainen, M; Venäläinen, M; Helminen, H; Niemi, R; Lehtimäki, T; Rantanen, T; Oksala, N. 2019. Anticancer research. 39: 73-79 A1 Journal article (refereed), original research
Finnish National Esophago-Gastric Cancer Cohort (FINEGO) for studying outcomes after oesophageal and gastric cancer surgery: a protocol for a retrospective, population-based, nationwide cohort study in Finland
Kauppila, JH; Ohtonen, P; Karttunen, TJ; Kokkola, A; Laine, S; Rantanen, T; Ristimäki, A; Räsänen, JV; Saarnio, J; Sihvo, E; Toikkanen, V; Tyrväinen, T. 2019. BMJ open. 9: e024094 A1 Journal article (refereed), original research
Malignant Peritoneal Mesothelioma: Treatment Options and Survival
Salo, SAS; Ilonen, I; Laaksonen, S; Myllärniemi, M; Salo, JA; Rantanen, T. 2019. Anticancer research. 39: 839-845 A1 Journal article (refereed), original research
Overexpression of HSP27 and HSP70 is associated with decreased survival among patients with esophageal adenocarcinoma
Söderstrom, Henna K; Kauppi, Juha T; Oksala, Niku; Paavonen, Timo; Krogerus, Leena; Räsänen, Jan; Rantanen, Tuomo. 2019. World journal of clinical cases. 7: 260-269 A1 Journal article (refereed), original research
Prospective multicentre cohort trial on acute appendicitis and microbiota, aetiology and effects of antimicrobial treatment: study protocol for the MAPPAC (Microbiology APPendicitis ACuta) trial
Vanhatalo, Sanja; Munukka, Eveliina; Sippola, Suvi; Jalkanen, Sirpa; Grönroos, Juha; Marttila, Harri; Eerola, Erkki; Hurme, Saija; Hakanen, Antti J; Salminen, Paulina; The APPAC collaborative study group [incl. Rantanen, Tuomo; Paajanen, Hannu]. 2019. BMJ open. 9: e031137 A1 Journal article (refereed), original research
A randomised placebo-controlled double-blind multicentre trial comparing antibiotic therapy with placebo in the treatment of uncomplicated acute appendicitis: APPAC III trial study protocol
Sippola, S; Grönroos, J; Sallinen, V; Rautio, T; Nordström, P; Rantanen, T; Hurme, S; Leppäniemi, A; Meriläinen, S; Laukkarinen, J; Savolainen, H; Virtanen, J; Salminen, P. 2018. BMJ open. 8: e023623 A1 Journal article (refereed), original research
Altered polyamine profiles in colorectal cancer
Venäläinen, Markus K; Roine, Antti N; Häkkinen, Merja R; Vepsäläinen, Jouko J; Kumpulainen, Pekka S; Kiviniemi, Mikko S; Lehtimäki, Terho; Oksala, Niku K; Rantanen, Tuomo K. 2018. Anticancer research. 38: 3601-3607 A1 Journal article (refereed), original research
Appendiceal neoplasm risk associated with complicated acute appendicitis - a population based study
Lietzén, E; Grönroos, JM; Mecklin, J-P; Leppäniemi, A; Nordström, P; Rautio, T; Rantanen, T; Sand, J; Paajanen, H; Kaljonen, A; Salminen, P. 2018. International journal of colorectal disease. 2019; 34: 39-46 A1 Journal article (refereed), original research
Blood Transfusions in Major Pancreatic Surgery: A 10-Year Cohort Study Including 1404 Patients Undergoing Pancreatic Resections in Finland
Lammi, JP; Eskelinen, M; Tuimala, J; Saarnio, J; Rantanen, T. 2018. Scandinavian journal of surgery. 2019; 108: 1-6 A1 Journal article (refereed), original research
Cholecystectomy Patients with High Plasma Level of Catalase Have Significantly Lower Analgesia Requirement: A Prospective Study of Two Different Cholecystectomy Techniques with Special Reference to Patients with Cancer
Saimanen, Iina; Kuosmanen, Viivi; Kärkkäinen, Jari; Selander, Tuomas; Aspinen, Samuli; Holopainen, Anu; Rantanen, Tuomo; Eskelinen, Matti. 2018. Anticancer research. 38: 5417-5422 A1 Journal article (refereed), original research
Five-Year Follow-up of Antibiotic Therapy for Uncomplicated Acute Appendicitis in the APPAC Randomized Clinical Trial
Salminen, Paulina; Tuominen, Risto; Paajanen, Hannu; Rautio, Tero; Nordström, Pia; Aarnio, Markku; Rantanen, Tuomo; Hurme, Saija; Mecklin, Jukka-Pekka; Sand, Juhani; Virtanen, Johanna; Jartti, Airi; Grönroos, Juha M. 2018. JAMA : Journal of the American Medical Association. 320: 1259-1265 A1 Journal article (refereed), original research
Need of Emergency Surgery in Elderly Patients with Upper Gastrointestinal Bleeding: Survival Analysis during 2009-2015
Miilunpohja, S; Kärkkäinen, J; Hartikainen, J; Jyrkkä, J; Rantanen, T; Paajanen, H. 2018. Digestive surgery. 2019; 36: 20-26 A1 Journal article (refereed), original research
Optimising the antibiotic treatment of uncomplicated acute appendicitis: a protocol for a multicentre randomised clinical trial (APPAC II trial)
Haijanen, J; Sippola, S; Grönroos, J; Rautio, T; Nordström, P; Rantanen, T; Aarnio, M; Ilves, I; Hurme, S; Marttila, H; Virtanen, J; Mattila, A; Paajanen, H; Salminen, P. 2018. Bmc surgery. 18: 117 A1 Journal article (refereed), original research
Risk of Appendiceal Neoplasm in Periappendicular Abscess in Patients Treated With Interval Appendectomy vs Follow-up With Magnetic Resonance Imaging: 1-year Outcomes of the Peri-Appendicitis Acuta Randomized Clinical Trial
Mällinen, Jari; Rautio, Tero, Grönroos, Juha; Rantanen, Tuomo; Nordström, Pia; Savolainen, Heini; Ohtonen, Pasi; Hurme, Saija; Salminen, Paulina. 2018. JAMA surgery. 2019; 154: 200-207 A1 Journal article (refereed), original research
Does Nissen Fundoplication Provide Lifelong Reflux Control? Symptomatic Outcome After 31-33 Years
Neuvonen P, Sand J, Matikainen M, Rantanen T. 2017. World journal of surgery. 41: 2046-2052 A1 Journal article (refereed), original research
Does rectus sheath block analgesia alter levels of the oxidative stress biomarker glutathione peroxidase: A randomised trial of patients with cancer and benign disease
Purdy M, Kärkkäinen J, Kokki M, Anttila M, Aspinen S, Juvonen P, Kokki H, Pulkki K, Rantanen T, Eskelinen M. 2017. Anticancer research. 37: 897-902 A1 Journal article (refereed), original research
Economic evaluation of antibiotic therapy versus appendicectomy for the treatment of uncomplicated acute appendicitis from the APPAC randomized clinical trial
Sippola S, Grönroos J, Tuominen R, Paajanen H, Rautio T, Nordström P, Aarnio M, Rantanen T, Hurme S, Salminen P. 2017. British journal of surgery. 104: 1355-1361 A1 Journal article (refereed), original research
Epidemiology of malignant peritoneal mesothelioma: A population-based study
Salo Silja AS, Ilonen Ilkka, Laaksonen Sanna, Myllärniemi Marjukka, Salo Jarmo A, Rantanen Tuomo. 2017. Cancer epidemiology. 51: 81-86 A1 Journal article (refereed), original research
Long-term mortality and causes of death in endoscopically verified upper gastrointestinal bleeding: comparison of bleeding patients and population controls
Miilunpohja S, Jyrkkä J, Kärkkäinen J, Kastarinen H, Heikkinen M, Paajanen H, Rantanen T, Hartikainen J. 2017. Scandinavian journal of gastroenterology. 52: 1211-1218 A1 Journal article (refereed), original research
Outcomes of high-frequency gastric electric stimulation for the treatment of severe, medically refractory gastroparesis in Finland
Laine, M; Sirén, J; Koskenpato, J; Punkkinen, J; Rantanen, T; Typpö, I; Kokkola, A; Sallinen, V. 2017. Scandinavian journal of surgery. 2018; 107: 124-129 A1 Journal article (refereed), original research
The accuracy of the computed tomography diagnosis of acute appendicitis:Does the experience of the radiologist matter?
Lietzén E, Salminen P, Rinta-Kiikka I, Paajanen H, Rautio T, Nordström P, Aarnio M, Rantanen T, Sand J, Mecklin JP, Jartti A, Virtanen J, Ohtonen P, Ånäs N, Grönroos JM. 2017. Scandinavian journal of surgery. 2018; 107: 43-47 A1 Journal article (refereed), original research
Adenocarcinoma of the Oesophagus and Oesophagogastric Junction: Analysis of Incidence and Risk Factors
Rantanen Tuomo, Oksala Niku, Sand Juhani. 2016. Anticancer research. 36: 2323-2329 A1 Journal article (refereed), original research
Clinical and laboratory findings in the diagnosis of right lower quadrant abdominal pain: outcome analysis of the APPAC trial
Lietzén E, Ilves I, Salminen P, Paajanen H, Rautio T, Nordström P, Aarnio M, Rantanen T, Kauko T, Jartti A, Sand J, Mecklin JP, Grönroos JM. 2016. Clinical chemistry and laboratory medicine. [epub ahead of print 24 March 2016]: - A1 Journal article (refereed), original research
Is preoperative distinction between complicated and uncomplicated acute appendicitis feasible without imaging?
Lietzén Elina, Mällinen Jari, Grönroos Juha M, Rautio Tero, Paajanen Hannu, Nordström Pia, Aarnio Markku, Rantanen Tuomo, Sand Juhani, Mecklin Jukka-Pekka, Jartti Airi, Virtanen Johanna, Ohtonen Pasi, Salminen Paulina. 2016. Surgery. 160: 789-795 A1 Journal article (refereed), original research
Long-Term Effect of Endoscopic Sympathetic Nerve Reconstruction for Side Effects after Endoscopic Sympathectomy
Rantanen Tuomo, Telaranta Timo. 2016. Thoracic and cardiovascular surgeon. 65: 484-490 A1 Journal article (refereed), original research
Mortality Related to Appendectomy: a Population Based Analysis over Two Decades in Finland
Kotaluoto Sannamari, Ukkonen Mika, Pauniaho Satu-Liisa, Helminen Mika, Sand Juhani, Rantanen Tuomo. 2016. World journal of surgery. [First online 17 Aug 2016]: 1-6 A1 Journal article (refereed), original research
Severe Sepsis in Elderly Patients Undergoing Gastrointestinal Surgery - a Prospective Multicenter Follow-up Study of Finnish Intensive Care Units
Ukkonen Mika, Karlsson Sari, Laukkarinen Johanna, Rantanen Tuomo, Paajanen Hannu, Finnsepsis Study Group. 2016. Journal of gastrointestinal surgery. 20: 1028-1033 A1 Journal article (refereed), original research
Alcohol Abuse Increases Rebleeding Risk and Mortality in Patients with Non-variceal Upper Gastrointestinal Bleeding
Kärkkäinen Jussi M, Miilunpohja Sami, Rantanen Tuomo, Koskela Jenni M, Jyrkkä Johanna, Hartikainen Juha, Paajanen Hannu. 2015. Digestive diseases and sciences. published online 16 Jul 2015: - A1 Journal article (refereed), original research
Antibiotic Therapy vs Appendectomy for Treatment of Uncomplicated Acute Appendicitis: The APPAC Randomized Clinical Trial
Salminen Paulina, Paajanen Hannu, Rautio Tero, Nordström Pia, Aarnio Markku, Rantanen Tuomo, Tuominen Risto, Hurme Saija, Virtanen Johanna, Mecklin Jukka-Pekka, Sand Juhani, Jartti Airi, Rinta-Kiikka Irina, Grönroos Juha M. 2015. JAMA : Journal of the American Medical Association. 313: 2340-2348 A1 Journal article (refereed), original research
Emergency Abdominal Operations in the Elderly: A Multivariate Regression Analysis of 430 Consecutive Patients with Acute Abdomen
Ukkonen Mika, Kivivuori Antti, Rantanen Tuomo, Paajanen Hannu. 2015. World journal of surgery. 39: 2854-2861 A1 Journal article (refereed), original research
Esophageal Ulcer as a Cause of Death: A Population-Based Study. Mortality of Esophageal Ulcer Disease
Rantanen TK, Sihvo EI, Räsänen JV, Hynninen M, Salo JA. 2015. Digestion. 91: 272-276 A1 Journal article (refereed), original research
Severe Complications of Laparoscopic and Conventional Appendectomy Reported to the Finnish Patient Insurance Centre
Kotaluoto Sannamari, Pauniaho Satu-Liisa K, Helminen Mika T, Sand Juhani A, Rantanen Tuomo K. 2015. World journal of surgery. 2016; 40: 277-283 A1 Journal article (refereed), original research
Continuous Absorbable Intradermal Sutures Yield Better Cosmetic Results than Nonabsorbable Interrupted Sutures in Open Appendectomy Wounds: A Prospective, Randomized Trial
Koskela A, Kotaluoto S, Kaartinen I, Pauniaho SL, Rantanen T, Kuokkanen H. 2014. World journal of surgery. 38: 1044-1050 A1 Journal article (refereed), original research
Effect of omeprazole dose, nonsteroidal anti-inflammatory agents, and smoking on repair mechanisms in acute peptic ulcer bleeding
Rantanen T, Udd M, Honkanen T, Miettinen P, Kärjä V, Rantanen L, Julkunen R, Mustonen H, Paavonen T, Oksala N. 2014. Digestive diseases and sciences. 59: 2666-2674 A1 Journal article (refereed), original research
Endoscopic evaluation of laparoscopic nissen fundoplication: 89 % success rate 10 years after surgery
Neuvonen P1, Iivonen M, Rantanen T. 2014. World journal of surgery. 38: 882-889 A1 Journal article (refereed), original research
Health-related quality of life 10 years after laparoscopic Nissen fundoplication-results of a community-based hospital
Neuvonen P, Iivonen M, Sintonen H, Rantanen T. 2014. Journal of laparoendoscopic and advanced surgical techniques. 24: 134-138 A1 Journal article (refereed), original research
Refluksileikkaus sittenkin lääkitystä kustannustehokkaampi?
Rantanen Tuomo. 2014. Duodecim. 130: 475-481 A2 Review article, Literature review, Systematic review

University of Eastern Finland Joensuu, Kuopio © University of Eastern Finland

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Tuomo Rantanen

Research groups

Epidural analgesia during esophagectomy and esophageal cancer prognosis: A population‐based nationwide study in Finland

Incidence trends of surgical complications after oesophagectomy for oesophageal cancer: a population-based, nationwide cohort study in Finland over 30 years

Preoperative predictors of postoperative complications after gastrectomy for gastric cancer, a population-based study in Finland

A randomized double-blind noninferiority clinical multicenter trial on oral moxifloxacin versus placebo in the outpatient treatment of uncomplicated acute appendicitis: APPAC IV study protocol

Comparison of Postoperative Complications After Gastrectomy for Gastric Cancer with Antecolic Versus Retrocolic Reconstruction: A Population-Based Study

Impact of Splenectomy on Long-term Outcomes after Gastrectomy for Gastric Cancer - a Population-based Study

Impact of an appendicolith and its characteristics on the severity of acute appendicitis

Intraoperative Bleeding Complications Leading to Blood Transfusions (BloTs) in 17,412 Cholecystectomies in Finland: A Study With Special Reference to Elderly Patients

Postoperative Delayed Emptying after Total, Subtotal, or Distal Gastrectomy for Gastric Cancer - a Population-based Study

Stapled vs handsewn anastomosis and anastomotic leaks in gastric cancer surgery—a population-based nationwide study in Finland

Three-Year Outcomes of Oral Antibiotics vs Intravenous and Oral Antibiotics for Uncomplicated Acute Appendicitis

Five-year Survival after McKeown Compared to Ivor-Lewis Esophagectomy for Esophageal Cancer: A Population-based Nationwide Study in Finland

Five-year follow-up of appendiceal neoplasm risk in periappendicular abscess in the Peri-Appendicitis Acuta Randomized Clinical Trial

Laparoscopic cholecystectomy versus antibiotic therapy for acute cholecystitis in patients over 75 years: Randomized clinical trial and retrospective cohort study

Population-based nationwide incidence of complications after gastrectomy for gastric adenocarcinoma in Finland

Postoperative Complications After Neoadjuvant Chemotherapy Versus Upfront Surgery in Gastric Adenocarcinoma: A Population-Based Nationwide Study in Finland

Preoperative Esophageal Stenting and 5-Year Survival in Patients Undergoing Esophagectomy for Esophageal Cancer: a Population-Based Nationwide Study from Finland

Wait-and-see strategy is justified after ERCP and endoscopic sphincterotomy in elderly patients with common biliary duct stones

ASO Visual Abstract: Long-Term Survival after Transhiatal Compared with Transthoracic Esophagectomy—a Population-Based Nationwide Study in Finland

Antibiotics versus placebo in adults with CT-confirmed uncomplicated acute appendicitis (APPAC III): randomized double-blind superiority trial

Long-Term Survival After Transhiatal Versus Transthoracic Esophagectomy: A Population-Based Nationwide Study in Finland

Robotic versus hybrid assisted ventral hernia repair: a prospective one-year comparative study of clinical outcomes

The association between appendicitis severity and patient age with appendiceal neoplasm histology : a population-based study

Discrimination between Pancreatic Cancer, Pancreatitis and Healthy Controls Using Urinary Polyamine Panel

Effect of Oral Moxifloxacin vs Intravenous Ertapenem Plus Oral Levofloxacin for Treatment of Uncomplicated Acute Appendicitis: The APPAC II Randomized Clinical Trial

Fatal complications after an interrupted gastric bypass operation in a patient with non-alcoholic fatty liver disease and massive obesity: a case report

The Importance of Intestinal Length in Triglyceride Metabolism and in Predicting the Outcomes of Comorbidities in Laparoscopic Roux-en-Y Gastric Bypass-a Narrative Review

Cohort profile: a nationwide population-based retrospective assessment of oesophageal cancer in the Finnish National Esophago-Gastric Cancer Cohort (FINEGO)

Cohort profile: gastric cancer in the population-based, Finnish National Esophago-Gastric Cancer Cohort (FINEGO) Study

Perioperative Changes in Hemoglobin Levels During Major Hepatopancreatic Surgery in Transfused and Non-Transfused Patients

Prognostic role of radiological peritoneal cancer index in malignant peritoneal mesothelioma: national cohort study

Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis A Secondary Analysis of a Randomized Clinical Trial

Superior primary fascial closure rate and lower mortality after open abdomen using negative pressure wound therapy with continuous fascial traction.

Cost analysis of antibiotic therapy versus appendectomy for treatment of uncomplicated acute appendicitis: 5-year results of the APPAC randomized clinical trial

Detection of Pancreatic Cancer by Urine Volatile Organic Compound Analysis

Finnish National Esophago-Gastric Cancer Cohort (FINEGO) for studying outcomes after oesophageal and gastric cancer surgery: a protocol for a retrospective, population-based, nationwide cohort study in Finland

Malignant Peritoneal Mesothelioma: Treatment Options and Survival

Overexpression of HSP27 and HSP70 is associated with decreased survival among patients with esophageal adenocarcinoma

Prospective multicentre cohort trial on acute appendicitis and microbiota, aetiology and effects of antimicrobial treatment: study protocol for the MAPPAC (Microbiology APPendicitis ACuta) trial

A randomised placebo-controlled double-blind multicentre trial comparing antibiotic therapy with placebo in the treatment of uncomplicated acute appendicitis: APPAC III trial study protocol

Altered polyamine profiles in colorectal cancer

Appendiceal neoplasm risk associated with complicated acute appendicitis - a population based study

Blood Transfusions in Major Pancreatic Surgery: A 10-Year Cohort Study Including 1404 Patients Undergoing Pancreatic Resections in Finland

Cholecystectomy Patients with High Plasma Level of Catalase Have Significantly Lower Analgesia Requirement: A Prospective Study of Two Different Cholecystectomy Techniques with Special Reference to Patients with Cancer

Five-Year Follow-up of Antibiotic Therapy for Uncomplicated Acute Appendicitis in the APPAC Randomized Clinical Trial

Need of Emergency Surgery in Elderly Patients with Upper Gastrointestinal Bleeding: Survival Analysis during 2009-2015

Optimising the antibiotic treatment of uncomplicated acute appendicitis: a protocol for a multicentre randomised clinical trial (APPAC II trial)

Risk of Appendiceal Neoplasm in Periappendicular Abscess in Patients Treated With Interval Appendectomy vs Follow-up With Magnetic Resonance Imaging: 1-year Outcomes of the Peri-Appendicitis Acuta Randomized Clinical Trial

Does Nissen Fundoplication Provide Lifelong Reflux Control? Symptomatic Outcome After 31-33 Years

Does rectus sheath block analgesia alter levels of the oxidative stress biomarker glutathione peroxidase: A randomised trial of patients with cancer and benign disease

Economic evaluation of antibiotic therapy versus appendicectomy for the treatment of uncomplicated acute appendicitis from the APPAC randomized clinical trial

Epidemiology of malignant peritoneal mesothelioma: A population-based study

Long-term mortality and causes of death in endoscopically verified upper gastrointestinal bleeding: comparison of bleeding patients and population controls

Outcomes of high-frequency gastric electric stimulation for the treatment of severe, medically refractory gastroparesis in Finland

The accuracy of the computed tomography diagnosis of acute appendicitis:Does the experience of the radiologist matter?

Adenocarcinoma of the Oesophagus and Oesophagogastric Junction: Analysis of Incidence and Risk Factors

Clinical and laboratory findings in the diagnosis of right lower quadrant abdominal pain: outcome analysis of the APPAC trial

Is preoperative distinction between complicated and uncomplicated acute appendicitis feasible without imaging?

Long-Term Effect of Endoscopic Sympathetic Nerve Reconstruction for Side Effects after Endoscopic Sympathectomy

Mortality Related to Appendectomy: a Population Based Analysis over Two Decades in Finland

Severe Sepsis in Elderly Patients Undergoing Gastrointestinal Surgery - a Prospective Multicenter Follow-up Study of Finnish Intensive Care Units

Alcohol Abuse Increases Rebleeding Risk and Mortality in Patients with Non-variceal Upper Gastrointestinal Bleeding

Antibiotic Therapy vs Appendectomy for Treatment of Uncomplicated Acute Appendicitis: The APPAC Randomized Clinical Trial

Emergency Abdominal Operations in the Elderly: A Multivariate Regression Analysis of 430 Consecutive Patients with Acute Abdomen

Esophageal Ulcer as a Cause of Death: A Population-Based Study. Mortality of Esophageal Ulcer Disease

Severe Complications of Laparoscopic and Conventional Appendectomy Reported to the Finnish Patient Insurance Centre

Continuous Absorbable Intradermal Sutures Yield Better Cosmetic Results than Nonabsorbable Interrupted Sutures in Open Appendectomy Wounds: A Prospective, Randomized Trial

Effect of omeprazole dose, nonsteroidal anti-inflammatory agents, and smoking on repair mechanisms in acute peptic ulcer bleeding

Endoscopic evaluation of laparoscopic nissen fundoplication: 89 % success rate 10 years after surgery

Health-related quality of life 10 years after laparoscopic Nissen fundoplication-results of a community-based hospital

Refluksileikkaus sittenkin lääkitystä kustannustehokkaampi?