Ville Männistö
Deputy Head of Unit
Professor
Professor of Gastroenterology
Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences
Research groups
Publications
84/84 items-
Adipose single cell epigenome and transcriptome localize genetic risk for cardiometabolic disease and accelerated aging
Lee, Seung Hyuk T; Kar, Asha; Gelev, Kyla Z; Chen, Zeyuan Johnson; Das, Sankha Subhra; Heinonen, Sini; Saarinen, Tuure; Vaittinen, Maija; Kaminska, Dorota; Peltoniemi, Hilkka; Luo, Chongyuan; Juuti, Anne; Männistö, Ville; Pihlajamäki, Jussi; Kaikkonen, Minna U; Pietiläinen, Kirsi H; Balliu, Brunilda; Pajukanta, Päivi, 2026, Nature communications, 17, 5469. A1 Journal article (refereed), original research -
Decreased degree of adipocyte differentiation in visceral adipose tissue contributes to metabolic dysfunction-associated steatotic liver disease
Gelev, Kyla Z; Lee, Seung Hyuk T; Alvarez, Marcus; Mancina, Rosellina M; Tavaglione, Federica; Jamialahmadi, Oveis; Vespasiani-Gentilucci, Umberto; Kar, Asha; Wang, Zitian; Kaminska, Dorota; Kaikkonen, Minna U; Männistö, Ville; Heinonen, Sini; Saarinen, Tuure; Juuti, Anne; Pietiläinen, Kirsi H; Pihlajamäki, Jussi; Romeo, Stefano; Pajukanta, Päivi, 2026, Nature communications, 17, 7101. A1 Journal article (refereed), original research -
Fibrosis-4 index screening beyond hepatology: a signal of systemic vulnerability
Åberg, Fredrik; Männistö, Ville, 2026, Polskie archiwum medycyny wewnetrznej, 136, 3, 17258. B1 Non-refereed journal articles -
Identification of a Functional CYP2C8 Variant Allele that Alters Splicing, Reduces Protein Expression, and Increases Drug Exposure
Mykkänen, Anssi JH; Hirvensalo, Päivi; Klein, Kathrin; Kaminska, Dorota; Grube, Markus; Tapaninen, Tuija; Kiiski, Johanna I; Neuvonen, Mikko; Männistö, Ville T; Pihlajamäki, Jussi; Tzvetkov, Mladen; Schwab, Matthias; Tornio, Aleksi; Backman, Janne T; Niemi, Mikko, 2026, Clinical pharmacology and therapeutics, [First published: 01 July 2026], 1-13. A1 Journal article (refereed), original research -
Liver Metabolomic Profiling Reveals Distinct Signatures Between Steatosis and Metabolic Dysfunction‐Associated Steatohepatitis
Palomurto, Saana; Flam, Emily; Kaminska, Dorota; Virtanen, Kirsi A; Kärjä, Vesa; Käkelä, Pirjo; Pajukanta, Päivi; Eberlé, Delphine; Haas, Joel T; Raverdy, Violeta; Caiazzo, Robert; Pattou, François; Staels, Bart; Pihlajamäki, Jussi; Männistö, Ville, 2026, Liver international, 46, 3, 1-13. A1 Journal article (refereed), original research -
Deep phenotyping of patients with MASLD upon high-intensity interval training
Houttu, Veera; Boulund, Ulrika; Troelstra, Marian; Csader, Susanne; Stols-Gonçalves, Daniela; Mak, Anne Linde; Dijk, Anne-Marieke van; Bouts, Julia; Winkelmeijer, Maaike; Verdoes, Xanthe; van den Berg-Faay, Sandra; Lek, Donne; Ronteltap, Ted; de Haan, Ferdinand; Jorstad, Harald; Männistö, Ville; Savonen, Kai; Pentikäinen, Heikki; Hanhineva, Kati; Babu, Ambrin Farizah; Panagiotou, Gianni; van Delden, Otto; Verheij, Joanne; Doukas, Michial; Nederveen, Aart; Schwab, Ursula; Grefhorst, Aldo; Nieuwdo, 2025, JHEP reports, 7, 3, 101289. A1 Journal article (refereed), original research -
Evidence-based criteria for identifying at-risk individuals requiring liver disease screening
Åberg, Fredrik; Männistö, Ville; Asteljoki, Juho; Salomaa, Veikko; Jula, Antti; Lundqvist, Annamari; Männistö, Satu; Perola, Markus; Luukkonen, Panu K, 2025, Hepatology communications, 9, 4, e0679. A1 Journal article (refereed), original research -
Indole-3-propionic acid promotes hepatic stellate cells inactivation
Ilha, Mariana; Sehgal, Ratika; Matilainen, Johanna; Rilla, Kirsi; Kaminska, Dorota; Gandhi, Shrey; Männistö, Ville; Ling, Charlotte; Romeo, Stefano; Pajukanta, Päivi; Pirinen, Eija; Virtanen, Kirsi A.; Pietiläinen, Kirsi H.; Vaittinen, Maija; Pihlajamäki, Jussi, 2025, Journal of translational medicine, 23, 1, 253. A1 Journal article (refereed), original research -
Metabolic dysfunction-associated steatotic liver disease alters fatty acid profiles in the liver and adipose tissue
Palomurto, Saana; Virtanen, Kirsi A; Kärjä, Vesa; Schwab, Ursula; Kaminska, Dorota; Käkelä, Pirjo; Pihlajamäki, Jussi; Männistö, Ville, 2025, Journal of clinical endocrinology and metabolism, 111, 1, e23-e31. A1 Journal article (refereed), original research -
Prediction of major liver-related events in the population using prognostic models
Åberg, Fredrik; Männistö, Ville, 2025, Gastroenterology report, 13, 1-12. A2 Review article, Literature review, Systematic review