Virve Kärkkäinen
Senior Researcher
Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences
Publications
12/12 items-
Altered tear fluid protein expression in persons with mild Alzheimer's disease in proteins involved in oxidative stress, protein synthesis, and energy metabolism
Kärkkäinen, Virve; Saari, Toni; Hannonen, Sanna; Rusanen, Minna; Lehtola, Juha-Matti; Uusitalo, Hannu; Leinonen, Ville; Thiede, Bernd; Kaarniranta, Kai; Koivisto, Anne M; Utheim, Tor P. 2025. Journal of Alzheimer's disease. 105: 292-301 A1 Journal article (refereed), original research -
Neuroinflammation Markers in Tear Fluid of Mild Alzheimer’s Disease
Kärkkäinen, Virve; Saari, Toni; Rusanen, Minna; Uusitalo, Hannu; Leinonen, Ville; Thiede, Bernd; Kaarniranta, Kai; Koivisto, Anne M.; Utheim, Tor P.. 2025. Journal of molecular neuroscience. 75: . 73 A1 Journal article (refereed), original research -
The Annual Incidence of Vascular Dementia and Other Dementias: A Population-Based Study in Eastern Finland
Tuominen, Ada; Kärkkäinen, Virve; Jetsonen, Viivi; Selander, Tuomas; Lappalainen, Olli; Jäkälä, Pekka; Koivisto, Anne. 2025. Neuroepidemiology. [Epub ahead of print 12 Mar 2025]: 1-7 A1 Journal article (refereed), original research -
Gut Microbiome Changes in Patients With Idiopathic Normal Pressure Hydrocephalus
Brandt, Emilia; Koivisto, Anne; Pereira, Pedro; Mustanoja, Ella; Auvinen, Petri; Saari, Toni; Lehtola, Juha-Matti; Hannonen, Sanna; Rusanen, Minna; Leinonen, Ville; Scheperjans, Filip; Kärkkäinen, Virve. 2024. Alzheimer disease and associated disorders. 38: 133-139 A1 Journal article (refereed), original research -
Tear fluid reflects the altered protein expressions of Alzheimer's disease patients in proteins involved in protein repair and clearance system or the regulation of cytoskeleton
Kärkkäinen, V; Hannonen, S; Rusanen M; Lehtola, JM; Saari, T; Uusitalo, H; Leinonen, V; Thiede, B; Kaarniranta, K; Koivisto, AM; Utheim, T. 2024. Journal of Alzheimer's disease. [First published online November 18, 2024]: 1-8 A1 Journal article (refereed), original research -
Prevalence of pre-eclampsia in 265 patients with an intracranial aneurysm, 393 female relatives versus a control cohort: A case–control study
Kotikoski, Satu; Paavola, Juho; Nurmonen, Heidi J; Kärkkäinen, Virve; Huuskonen, Terhi J; Huttunen, Jukka; Koivisto, Timo; von und zu Fraunberg, Mikael; Jääskeläinen, Juha E; Lindgren, Antti E. 2023. European journal of neurology. 2024; 31: A1 Journal article (refereed), original research -
Computer-based Eye-tracking Analysis of King-Devick Test Differentiates Persons With Idiopathic Normal Pressure Hydrocephalus From Cognitively Unimpaired
Lehtola, Juha-Matti; Kärkkäinen, Virve; Andberg, Sami; Hannonen, Sanna; Rusanen, Minna; Saari, Toni; Korhonen, Ville; Hokkanen, Laura; Hallikainen, Merja; Hänninen, Tuomo; Kaarniranta, Kai; Bednarik, Roman; Leinonen, Ville; Koivisto, Anne M. 2022. Alzheimer disease and associated disorders. 36: 340-346 A1 Journal article (refereed), original research -
ADAMTS-4 promotes neurodegeneration in a mouse model of amyotrophic lateral sclerosis
Lemarchant S, Pomeshchik Y, Kidin I, Kärkkäinen V, Valonen P, Lehtonen S, Goldsteins G, Malm T, Kanninen K, Koistinaho J. 2016. Molecular neurodegeneration. 11: 10 A1 Journal article (refereed), original research -
Erratum to: ADAMTS-4 promotes neurodegeneration in a mouse model of amyotrophic lateral sclerosis
Lemarchant S, Pomeshchik Y, Kidin I, Kärkkäinen V, Valonen P, Lehtonen S, Goldsteins G, Malm T, Kanninen K, Koistinaho J. 2016. Molecular neurodegeneration. 11: 15 A1 Journal article (refereed), original research -
Metabotropic glutamate receptor 5 responses dictate differentiation of neural progenitors to NMDA-responsive cells in fragile X syndrome
Achuta VS, Grym H, Putkonen N, Louhivuori V, Kärkkäinen V, Koistinaho J, Roybon L, Castrén ML. 2016. Developmental neurobiology. [Epub ahead of print 28 July 2016]: 1-16 A1 Journal article (refereed), original research