JARI NISSINEN

Yhteystiedot

Julkaisut

• Nissinen J, Andrade P, Natunen T, Hiltunen M, Malm T, Kanninen K, Soares JI, Shatilloa O, Sallinen J, Ndode-Ekanea XE, Pitkänen A. 2017. Disease-modifying effect of atipamezole in a model of post-traumatic epilepsy. EPILEPSY RESEARCH 136: 18-34. 2017
• Andrade Pedro, Nissinen Jari, Pitkanen Asla. 2017. Generalized Seizures after Experimental Traumatic Brain Injury Occur at the Transition from Slow-Wave to Rapid-Eye-Movement Sleep. JOURNAL OF NEUROTRAUMA (NEW YORK NY) 34 7: 1482-1487. 2017
• Pitkänen A, Immonen R, Ndode-Ekane X, Gröhn O, Stöhr T, Nissinen J. 2014. Effect of lacosamide on structural damage and functional recovery after traumatic brain injury in rats. EPILEPSY RESEARCH 2014 May;108(4): 653-65. 2014
• Niskanen JP, Airaksinen AM, Sierra A, Huttunen JK, Nissinen J, Karjalainen PA, Pitkänen A, Gröhn OH. 2013. Monitoring functional impairment and recovery after traumatic brain injury in rats by FMRI. JOURNAL OF NEUROTRAUMA (NEW YORK NY) 2013 Apr 1;30(7): 546-56. 2013
• Ziyatdinova Sofya, Gurevicius Kestutis, Kutchiashvili Nino, Bolkvadze Tamuna, Nissinen Jari, Tanila Heikki, Pitkänen Asla. 2011. Spontaneous epileptiform discharges in a mouse model of Alzheimer's disease are suppressed by antiepileptic drugs that block sodium channels. EPILEPSY RESEARCH 94: 75-85. 2011
• Airaksinen AM, Niskanen JP, Chamberlain R, Huttunen JK, Nissinen J, Garwood M, Pitkänen A & Gröhn O. 2010. Simultaneous fMRI and local field potential measurements during epileptic seizures in medetomidine-sedated rats using raser pulse sequence MAGNETIC RESONANCE IN MEDICINE 64: 1191-1199. 2010
• Noè F, Pool AH, Nissinen J, Gobbi M, Bland R, Rizzi M, Balducci C, Ferraguti F, Sperk G, During MJ, Pitkänen A, Vezzani A. 2008. Neuropeptide Y gene therapy decreases chronic spontaneous seizures in a rat model of temporal lobe epilepsy. BRAIN 131 6: 1506-1515. 2008
• Pitkänen A, Kharatisvili I, Karhunen H, Lukasiuk K, Immonen R, Nairismägi J, Gröhn O, Nissinen J. 2007. Epileptogenesis in experimental models. EPILEPSIA. SUPPLEMENT 48 2: 13-20. 2007
• Pitkänen A, Mathiesen C, Rønn LCB, Møller A, Nissinen J. 2007. Effect of novel AMPA antagonist, NS1209, on status epilepticus. An experimental study in rat EPILEPSY RESEARCH 74 1: 45-54. 2007
• Karhunen H, Bezvenyuk Z, Nissinen J, Sivenius J, Jolkkonen J, Pitkänen A, Sivenius J. 2007. Epileptogenesis after cortical photothrombotic brain lesion in rats. NEUROSCIENCE 148 1: 314-324. 2007
• Noe' F, Nissinen J, Pitkänen A, Gobbi M, Sperk G, During M, Vezzani A. 2007. Gene therapy in epilepsy: The focus on NPY. PEPTIDES 28 2: 377-383. 2007
• Nissinen J, Pitkänen A. 2007. Effect of antiepileptic drugs on spontaneous seizures in epileptic rats. EPILEPSY RESEARCH 73 2: 181-191. 2007
• Goffin K, Nissinen J, Van Laere K, Pitkänen A. 2007. Cyclicity of spontaneous recurrent seizures in pilocarpine model of temporal lobe epilepsy in rat. EXPERIMENTAL NEUROLOGY 205: 501-505. 2007
• Karhunen H, Nissinen J, Sivenius J, Jolkkonen J, Pitkänen A. 2006. A long-term video-EEG and behavioral follow-up after endothelin-1 induced middle cerebral artery occlusion in rats. EPILEPSY RESEARCH 72: 25-38. 2006
• Kemppainen EJS, Nissinen J, Pitkänen A. 2006. Fear conditioning is impaired in systemic kainic acid and amygdala-stimulation models of epilepsy. EPILEPSIA (NY) 47 5: 820-829. 2006
• Kharatishvili I, Nissinen JP, McIntosh TK, Pitkänen A. 2006. A model of posttraumatic epilepsy induced by lateral fluid-percussion brain injury in rats. NEUROSCIENCE 140: 685-697. 2006
• Nissinen J. 2006. Characterization of a Rat Model of Human Temporal Lobe Epilepsy. Kuopion yliopiston julkaisuja G.- A.I. Virtanen -instituutti. 2006
• Päivinen N, Lammi S, Pitkänen A, Nissinen J, Penttonen M, Grönfors T. 2005. Epileptic seizure detection: A nonlinear viewpooint. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE 79 2: 151-159. 2005
• Pitkänen A, Kharatishvili I, Narkilahti S, Lukasiuk K, Nissinen J. 2005. Administration of diazepam during status epilepticus reduces development and severity of epilepsy in rat. EPILEPSY RESEARCH 63: 27-42. 2005
• Pirttilä TJ, Manninen A, Jutila L, Nissinen J, Kälviäinen R, Vapalahti M, Immonen A, Paljärvi L, Karkola K, Alafuzoff I, Mervaala E, Pitkänen A. 2005. Cystatin C expression is associated with granule cell dispersion in epilepsy. ANNALS OF NEUROLOGY 58 2: 211-223. 2005
• Nairismägi J, Gröhn OHJ, Kettunen MI, Nissinen J, Kauppinen RA, Pitkänen A. 2004. Progression of brain damage after status epilepticus and its association with epileptogenesis: a quantitative MRI study in a rat model of temporal lobe epilepy EPILEPSIA (NY) 45 9: 1024-1034. 2004
• Niittykoski M, Nissinen J, Penttonen M, Pitkänen A. 2004. Electrophysiologic changes in the lateral and basal amygdaloid nuclei in temporal lobe epilepsy: an in vitro study in epileptic rats. NEUROSCIENCE 124: 269-281. 2004
• Nissinen J, Large CH, Stratton SC, Pitkänen A. 2004. Effect of lamotrigine treatment on epileptogenesis: an experimental study in rat EPILEPSY RESEARCH 58 2-3: 119-132. 2004
• Pitkänen A, Narkilahti S, Bezvenyuk Z, Haapalinna A, Nissinen J. 2004. Atipamezole, an alfa2-adrenoceptor antagonist, has disease modifying effects on epileptogenesis in rats EPILEPSY RESEARCH 61: 119-140. 2004
• Karhunen H, Pitkänen A, Virtanen T, Gureviciene I, Pussinen R, Ylinen A, Sivenius J, Nissinen J, Jolkkonen J. 2003. Long-term functional consequences of transient occlusion of the middle cerebral artery in rats: a 1-year follow-up of the development of epileptogenesis and memory impairment in relation to sensorimotor deficits. EPILEPSY RESEARCH 54 1: 1-10. 2003
• Laurén HB, Pitkänen A, Nissinen J, Soini SL, Korpi ER, Holopainen IE. 2003. Selective changes in gamma-aminobutyric acid type A receptor subunits in the hippocampus in spontaneously seizing rats with chronic temporal lobe epilepsy. NEUROSCIENCE LETTERS 349: 58-62. 2003
• Narkilahti S, Nissinen J, Pitkänen A. 2003. Administration of caspase 3 inhibitor during and after status epilepticus in rat: effect on neuronal damage and epileptogenesis. NEUROPHARMACOLOGY 44: 1068-1088. 2003
• Pitkänen A, Nissinen J, Nairismägi J, Lukasiuk K, Gröhn OHJ, Miettinen R, Kauppinen R. 2002. Progression of neuronal damage after status epilepticus and during spontaneous seizures in a rat model of temporal lobe epilepsy: Sutula T, Pitkänen A, Do Seizures Damage the Brain.Elsevier. Progress in Brain Research. 67-83. 2002
• Lähteinen S, Pitkänen A, Saarelainen T, Nissinen J, Koponen E, Castrén E. 2002. Decreased BDNF signalling in transgenic mice reduces epileptogenesis. EUROPEAN JOURNAL OF NEUROSCIENCE (OXFORD) 15: 721-734. 2002
• Halonen T, Nissinen J, Pitkanen A. 2001. Effect of lamotrigine treatment on status epilepticus-induced neuronal damage and memory impairment in rat. EPILEPSY RESEARCH 46 3: 205-223. 2001
• Halonen T, Nissinen J, Pitkänen A. 2001. Chronic elevation of brain GABA levels beginning two days after status epilepticus does not prevent epileptogenesis in rats. NEUROPHARMACOLOGY 40 4: 536-550. 2001
• Nissinen J, Lukasiuk K, Pitkänen A. 2001. Is mossy fiber sprouting present at the time of the first spontaneous seizures in rat experimental temporal lobe epilepsy?. HIPPOCAMPUS 11 3: 299-310. 2001
• Nissinen J, Halonen T, Koivisto E, Pitkänen A. 2000. A new model of chronic temporal lobe epilepsy induced by electrical stimulation of the amygdala in rat. EPILEPSY RESEARCH 38 2-3: 177-205. 2000
• Pitkänen A, Nissinen J, Lukasiuk K, Jutila L, Paljärvi L, Salmenperä T, Karkola K, Vapalahti M, Ylinen A. 2000. Association between the density of mossy fiber sprouting and seizure frequency in experimental and human temporal lobe epilepsy EPILEPSIA. SUPPLEMENT 41 6: S24-S29. 2000
• Halonen T, Nissinen J, Pitkänen A. 1999. Neuroprotective effect of remacemide hydrochloride in a perforant pathway stimulation model of status epilepticus in the rat. EPILEPSY RESEARCH 34: 251-269. 1999
• Pitkänen A, Nissinen J, Jolkkonen E, Tuunanen J, Halonen T. 1999. Effects of vigabatrin treatment on status epilepticus-induced neuronal damage and mossy fiber sprouting in the rat hippocampus. EPILEPSY RESEARCH 33: 67-85. 1999
• Halonen T, Nissinen J, Jansen JA, Pitkänen A. 1996. Tiagabine prevents seizures, neuronal damage and memory impairment in experimental status epilepticus. EUROPEAN JOURNAL OF PHARMACOLOGY 299: 69-81. 1996
• Jolkkonen J, Halonen T, Jolkkonen E, Nissinen J, Pitkänen A. 1996. Seizure-induced damage to the hippocampus is prevented by modulation of the GABAergic system. NEUROREPORT 7: 2031-2035. 1996