Katja Kanninen
Professori
Professori
Terveystieteiden tiedekunta, A. I. Virtanen -instituutti
katja.kanninen@uef.fi | 046 921 0065
Johdan ’Soluneurobiologia’ -tutkimusryhmää A.I.Virtanen -instituutissa, jossa toimin professorina. Tutkimme ympäristön vaikutuksia aivoterveyteen ja Alzheimerin tautiin. Käytämme tutkimuksessa potilasperäisiä solumalleja.
Lisätietoa tutkimusryhmästä osoitteessa: https://uefconnect.uef.fi/en/group/cellular-neurobiology/#information
Julkaisut
76 kappaletta-
Regular Physical Exercise Modulates Iron Homeostasis in the 5xFAD Mouse Model of Alzheimer's Disease
Belaya, Irina; Kucháriková, Nina; Górová, Veronika; Kysenius, Kai; Hare, Dominic J.; Crouch, Peter J.; Malm, Tarja; Atalay, Mustafa; White, Anthony R.; Liddell, Jeffrey R.; Kanninen, Katja M.. International journal of molecular sciences 22 16: 8715. 2021 -
An arylthiazyne derivative is a potent inhibitor of lipid peroxidation and ferroptosis providing neuroprotection in vitro and in vivo
Keuters, Meike Hedwig; Keksa-Goldsteine, Velta; Dhungana, Hiramani; Huuskonen, Mikko T; Pomeshchik, Yuriy; Savchenko, Ekaterina; Korhonen, Paula K; Singh, Yajuvinder; Wojciechowski, Sara; Lehtonen, Šárka; Kanninen, Katja M; Malm, Tarja; Sirviö, Jouni; Muona, Anu; Koistinaho, Milla; Goldsteins, Gundars; Koistinaho, Jari. Scientific reports 11 1: 3518. 2021 -
Systemic inflammation induced changes in protein expression of ABC transporters and ionotropic glutamate receptor subunit 1 in the cerebral cortex of familial Alzheimer`s disease mouse model
Puris, Elena; Auriola, Seppo; Korhonen, Paula; Loppi, Sanna; Kanninen, Katja M; Malm, Tarja; Koistinaho, Jari; Gynther, Mikko. Journal of pharmaceutical sciences 110 12: 3953-3962. 2021 -
Metabolomic and lipidomic changes triggered by lipopolysaccharide-induced systemic inflammation in transgenic APdE9 mice
Puris, Elena; Kouril, Štepán; Najdekr, Lukáš; Loppi, Sanna; Korhonen, Paula; Kanninen, Katja M.; Malm, Tarja; Koistinaho, Jari; Friedecký, David; Gynther, Mikko. Scientific reports 11 1: 13076. 2021 -
Increased iron content in the heart of the Fmr1 knockout mouse
Talvio, Karo; Kanninen, Katja M; White, Anthony R; Koistinaho, Jari; Castrén, Maija L. Biometals 34 4: 947-954. 2021 -
Astrocyte remodeling in the beneficial effects of long-term voluntary exercise in Alzheimer's disease
Belaya, Irina; Ivanova, Mariia; Sorvari, Annika; Ilicic, Marina; Loppi, Sanna; Koivisto, Hennariikka; Varricchio, Alessandra; Tikkanen, Heikki; Walker, Frederick R; Atalay, Mustafa; Malm, Tarja; Grubman, Alexandra; Tanila, Heikki; Kanninen, Katja M. Journal of neuroinflammation 17 1: 271. 2020 -
Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-ß from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy
Carare, RO; Aldea, R; Agarwal, N; Bacskai, BJ; Bechman, I; Boche, D; Bu, G; Bulters, D; Clemens, A; Counts, SE; de Leon, M; Eide, PK; Fossati, S; Greenberg, SM; Hamel, E; Hawkes, CA; Koronyo-Hamaoui, M; Hainsworth, AH; Holtzman, D; Ihara, M; et al [incl. Kanninen, K; Leinonen, V; Malm, T]. Alzheimer's & dementia : diagnosis, assessment & disease monitoring 21 1: e12053. 2020 -
Impairment of mitochondrial function by particulate matter: Implications for the brain
Chew, S; Kolosowska, N; Saveleva, L; Malm, T; Kanninen, KM. Neurochemistry international 135: 104694. 2020 -
Urban air particulate matter induces mitochondrial dysfunction in human olfactory mucosal cells
Chew, Sweelin; Lampinen, Riikka; Saveleva, Liudmila; Korhonen, Paula; Mikhailov, Nikita; Grubman, Alexandra; Polo, Jose M; Wilson, Trevor; Komppula, Mika; Rönkkö, Teemu; Gu, Cheng; Mackay-Sim, Alan; Malm, Tarja; White, Anthony R; Jalava, Pasi; Kanninen, Katja M. Particle and fibre toxicology 17 1: 18. 2020 -
Proteomic and functional analyses in disease models reveal CLN5 protein involvement in mitochondrial dysfunction
Doccini, S; Morani, F; Nesti, C; Pezzini, F; Calza, G; Soliymani, R; Signore, G; Rocchiccioli, S; Kanninen, KM; Huuskonen, MT; Baumann, MH; Simonati, A; Lalowski, MM; Santorelli, FM. Cell death discovery 6 1: 18. 2020