Sanna-Kaisa Herukka

Kenvin, Sebastian; Torregrosa-Muñumer, Ruben; Reidelbach, Marco; Pennonen, Jana; Turkia, Jeremi J; Rannila, Erika; Kvist, Jouni; Sainio, Markus T; Huber, Nadine; Herukka, Sanna-Kaisa; Haapasalo, Annakaisa; Auranen, Mari; Trokovic, Ras; Sharma, Vivek; Ylikallio, Emil; Tyynismaa, Henna. 2022. Threshold of heteroplasmic truncating MT-ATP6 mutation in reprogramming, Notch hyperactivation and motor neuron metabolism Human molecular genetics [Corrected proof 19 Nov 2021]: 1 - 46. 2022

Katisko, Kasper; Cajanus, Antti; Huber, Nadine; Jääskeläinen, Olli; Kokkola, Tarja; Kärkkäinen, Virve; Rostalski, Hannah; Hartikainen, Paivi; Koivisto, Anne M; Hannonen, Sanna; Lehtola, Juha-Matti; Korhonen, Ville E; Helisalmi, Seppo; Koivumaa-Honkanen, Heli; Herukka, Sanna-Kaisa; Remes, Anne M; Solje, Eino; Haapasalo, Annakaisa. 2021. GFAP as a biomarker in frontotemporal dementia and primary psychiatric disorders: diagnostic and prognostic performance Journal of neurology neurosurgery and psychiatry 92 12: 1305-1312. 2021

Lukkarinen, Heikki; Tesseur, Ina; Pemberton, Darrel; Van Der Ark, Peter; Timmers, Maarten; Slemmon, Randy; Janssens, Luc; Streffer, Johannes; Van Nueten, Luc; Bottelbergs, Astrid; Rauramaa, Tuomas; Koivisto, Anne M.; Herukka, Sanna-Kaisa; Korhonen, Ville E.; Junkkari, Antti; Hiltunen, Mikko; Engelborghs, Sebastiaan; Blennowk, Kaj; Zetterbergk, Henrik; Kolb, Hartmuth C.; Leinonen, Ville. 2021. Time Trends of Cerebrospinal Fluid Biomarkers of Neurodegeneration in Idiopathic Normal Pressure Hydrocephalus Journal of Alzheimer's disease 80 4: 1629-1642. 2021

Niiranen, Marja; Kontkanen, Aleksi; Jääskeläinen, Olli; Tertsunen, Hanna-Mari; Selander, Tuomas; Hartikainen, Päivi; Huber, Nadine; Solje, Eino; Haapasalo, Annakaisa; Kokkola, Tarja; Lohioja, Tarja; Herukka, Sanna-Kaisa; Simula, Sakari; Remes, Anne M.. 2021. Serum GFAP and NfL levels in benign relapsing-remitting multiple sclerosis Multiple sclerosis and related disorders 56: 103280. 2021

Toft, Anders; Roos, Peter; Jääskeläinen, Olli; Musaeus, Christian Sandoe; Henriksen, Emil Elbaek; Johannsen, Peter; Nielsen, Troels Tolstrup; Herukka, Sanna-Kaisa; Hviid Simonsen, Anja; Nielsen, Jorgen Erik. 2021. Serum Neurofilament Light in Patients with Frontotemporal Dementia Caused by CHMP2B Mutation Dementia and geriatric cognitive disorders 49 6: 533-538. 2021

Vanninen, Aleksi; Nakajima, Madoka; Miyajima, Masakazu; Rauramaa, Tuomas; Kokki, Merja; Musialowicz, Tadeusz; Mäkinen, Petra M; Herukka, Sanna-Kaisa; Koivisto, Anne M; Jääskeläinen, Juha E; Hiltunen, Mikko; Leinonen, Ville. 2021. Elevated CSF LRG and Decreased Alzheimer's Disease Biomarkers in Idiopathic Normal Pressure Hydrocephalus Journal of clinical medicine 10 5: 1105. 2021

Kaipainen, Aku L; Pitkänen, Johanna; Haapalinna, Fanni; Jääskeläinen, Olli; Jokinen, Hanna; Melkas, Susanna; Erkinjuntti, Timo; Vanninen, Ritva; Koivisto, Anne M; Lötjönen, Jyrki; Koikkalainen, Juha; Herukka, Sanna-Kaisa; Julkunen, Valtteri. 2021. A novel CT-based automated analysis method provides comparable results with MRI in measuring brain atrophy and white matter lesions Neuroradiology 63 12: 2035-2046. 2021

Nakajima, Madoka; Rauramaa, Tuomas; Mäkinen, Petra M; Hiltunen, Mikko; Herukka, Sanna-Kaisa; Kokki, Merja; Musialowicz, Tadeusz; Jyrkkänen, Henna-Kaisa; Danner, Nils; Junkkari, Antti; Koivisto, Anne M; Jääskeläinen, Juha E; Miyajima, Masakazu; Ogino, Ikuko; Furuta, Akiko; Akiba, Chihiro; Kawamura, Kaito; Kamohara, Chihiro; Sugano, Hidenori; Tange, Yuichi; et al. [incl. Leinonen, Ville]. 2020. PTPR type Q in cerebrospinal fluid reflects ependymal cells dysfunction and is a potential biomarker for adult chronic hydrocephalus European journal of neurology 2021; 28 2: 389-400. 2020

Rhodius-Meester, HFM; van Maurik, IS; Koikkalainen, J; Tolonen, A; Frederiksen, KS; Hasselbalch, SG; Soininen, H; Herukka, SK; Remes, AM; Teunissen, CE; Barkhof, F; Pijnenburg, YAL; Scheltens, P; Lötjönen, J; van der Flier, WM. 2020. Selection of memory clinic patients for CSF biomarker assessment can be restricted to a quarter of cases by using computerized decision support, without compromising diagnostic accuracy PLoS ONE 15 1: e0226784. 2020

Rhodius-Meester, HFM; Paajanen, T; Koikkalainen, J; Mahdiani, S; Bruun, M; Baroni, M; Lemstra, AW; Scheltens, P; Herukka, SK; Pikkarainen, M; Hall, A; Hänninen, T; Ngandu, T; Kivipelto, M; van Gils, M; Hasselbalch, SG; Mecocci, P; Remes, A; Soininen, H; van der Flier, WM; Lötjönen, J. 2020. cCOG: A web-based cognitive test tool for detecting neurodegenerative disorders Alzheimer's & dementia : diagnosis, assessment & disease monitoring 12 1: e12083. 2020

Onatsu, Juha; Vanninen, Ritva; Jäkälä, Pekka; Mustonen, Pirjo; Pulkki, Kari; Korhonen, Miika; Hedman, Marja; Höglund, Kina; Blennow, Kaj; Zetterberg, Henrik; Herukka, Sanna-Kaisa; Taina, Mikko. 2020. Tau, S100B and NSE as Blood Biomarkers in Acute Cerebrovascular Events In vivo 34 5: 2577-2586. 2020

van Waalwijk van Doorn, Linda J C; Ghafoorian, Mohsen; van Leijsen, Esther M C; Claassen, Jurgen A H R; Arighi, Andrea; Bozzali, Marco; Cannas, Jorge; Cavedo, Enrica; Eusebi, Paolo; Farotti, Lucia; Fenoglio, Chiara; Fortea, Juan; Frisoni, Giovanni B; Galimberti, Daniela; Greco, Viviana; Herukka, Sanna-Kaisa; Liu, Yawu; Lleó, Alberto; de Mendonça, Alexandre; Nobili, Flavio M; et al. [incl. Pikkarai. 2020. White Matter Hyperintensities are No Major Confounder for Alzheimer's Disease Cerebrospinal Fluid Biomarkers Journal of Alzheimer's disease 2021; 79 1: 163-175. 2020

Muurling, Marijn; Rhodius-Meester, Hanneke; Pärkkä, Juha; van Gils, Mark; Frederiksen, Kristian S; Bruun, Marie; Hasselbalch, Steen G; Soininen, Hilkka; Herukka, Sanna-Kaisa; Hallikainen, Merja; Teunissen, Charlotte E; Visser, Pieter; Scheltens, Philip; van der Flier, Wiesje M; Mattila, Jussi; Lötjönen, Jyrki; de Boer, Casper. 2020. Gait Disturbances are Associated with Increased Cognitive Impairment and Cerebrospinal Fluid Tau Levels in a Memory Clinic Cohort Journal of Alzheimer's disease 76 3: 1061-1070. 2020

Kaipainen, Aku; Jääskeläinen, Olli; Liu, Yawu; Haapalinna, Fanni; Nykänen, Niko; Vanninen, Ritva; Koivisto, Anne M; Julkunen, Valtteri; Remes, Anne M; Herukka, Sanna-Kaisa. 2020. Cerebrospinal Fluid and MRI Biomarkers in Neurodegenerative Diseases: A Retrospective Memory Clinic-Based Study Journal of Alzheimer's disease 75 3: 751-765. 2020

Jääskeläinen, O; Hall, A; Tiainen, M; van Gils, M; Lötjönen, J; Kangas, AJ; Helisalmi, S; Pikkarainen, M; Hallikainen, M; Koivisto, A; Hartikainen, P; Hiltunen, M; Ala-Korpela, M; Soininen, P; Soininen, H; Herukka, S-K. 2020. Metabolic Profiles Help Discriminate Mild Cognitive Impairment from Dementia Stage in Alzheimer's Disease. Journal of Alzheimer's disease 74 1: 277-286. 2020

Hänninen, Katariina; Jääskeläinen, Olli; Herukka, Sanna-Kaisa; Soilu-Hänninen, Merja. 2020. Vitamin D supplementation and serum neurofilament light chain in interferon-beta-1b-treated MS patients Brain and behavior 10 9: e01772. 2020

Cajanus, Antti; Katisko, Kasper; Kontkanen, Aleksi; Jääskeläinen, Olli; Hartikainen, Päivi; Haapasalo, Annakaisa; Herukka, Sanna-Kaisa; Vanninen, Ritva; Solje, Eino; Hall, Anette; Remes, Anne. 2020. Serum neurofilament light chain in FTLD: association with C9orf72, clinical phenotype, and prognosis Annals of clinical and translational neurology 7 6: 903-910. 2020

Anttila, Margareta; Hartikainen, Sirpa; Herukka, Sanna-Kaisa; Kaasinen, Valtteri; Tolppanen, Anna-Maija. 2020. Parkinsonin taudin lääkkeiden erityiskorvausoikeuden saajien määrän muutos vuosina 1996-2015 Lääkärilehti 75 43-44: 2297-2303. 2020

van Maurik, IS; Vos, SJ; Bos, I; Bouwman, FH; Teunissen, CE; Scheltens, P; Barkhof, F; Frolich, L; Kornhuber; J; Wiltfang, J; Maier, W; Peters, O; Rüther, E; Nobili, F; Frisoni, GB; Spiru, L; Freund-Levi, Y; Wallin, AK; Hampel, H; Soininen, H; Tsolaki, M; et al. (incl. Herukka, SK). 2019. Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study The Lancet Neurology 18 11: 1034-1044. 2019

Tuusa, Jussi; Lindgren, Outi; Tertsunen, Hanna-Mari; Nishie, Wataru; Kokkonen, Nina; Huilaja, Laura; Izumi, Kentaro; Herukka, Sanna-Kaisa; Miettunen, Jouko; Shimizu, Hiroshi; Remes, Anne M; Tasanen, Kaisa. 2019. BP180 Autoantibodies Target Different Epitopes in Multiple Sclerosis or Alzheimer's Disease than in Bullous Pemphigoid Journal of investigative dermatology 139 2: 293-299. 2019

Rinne, JO; Suotunen, T; Rummukainen, J; Herukka, SK; Nerg, O; Koivisto, AM; Rauramaa, T; Någren, K; Hiltunen, M; Alafuzoff, I; Rinne, J; Jääskeläinen, JE; Soininen, H; Leinonen, V. 2019. [11C]PIB PET Is Associated with the Brain Biopsy Amyloid-ß Load in Subjects Examined for Normal Pressure Hydrocephalus Journal of Alzheimer's disease 67 4: 1343-1351. 2019

Onatsu, Juha; Vanninen, Ritva; Jäkälä, Pekka; Mustonen, Pirjo; Pulkki, Kari; Korhonen, Miika; Hedman, Marja; Zetterberg, Henrik; Blennow, Kaj; Höglund, Kina; Herukka, Sanna-Kaisa; Taina, Mikko. 2019. Serum Neurofilament Light Chain Concentration Correlates with Infarct Volume but Not Prognosis in Acute Ischemic Stroke Journal of stroke and cerebrovascular diseases 28 8: 2242-2249. 2019

Luikku, AJ; Hall, A; Nerg, O; Koivisto, AM; Hiltunen, M; Helisalmi, S; Herukka, SK; Junkkari, A; Sutela, A; Kojoukhova, M; Korhonen, V; Mattila, J; Lötjönen, J; Rummukainen, J; Alafuzoff, I; Jääskeläinen, JE; Remes, AM; Solomon, A; Kivipelto, M; Soininen, H; et al. [Incl. Rauramaa, T; Leinonen, V]. 2019. Predicting Development of Alzheimer's Disease in Patients with Shunted Idiopathic Normal Pressure Hydrocephalus Journal of Alzheimer's disease 71 4: 1233-1243. 2019

Katisko, K; Solje, E; Korhonen, P; Jääskeläinen, O; Loppi, S; Hartikainen, P; Koivisto, AM; Kontkanen, A; Korhonen, VE; Helisalmi, S; Malm, T; Herukka, SK; Remes, AM; Haapasalo, A. 2019. Peripheral inflammatory markers and clinical correlations in patients with frontotemporal lobar degeneration with and without the C9orf72 repeat expansion Journal of neurology 2020; 267: 76-86. 2019

Katisko, K; Cajanus, A; Jääskeläinen, O; Kontkanen, A; Hartikainen, P; Korhonen, VE; Helisalmi, S; Haapasalo, A; Koivumaa-Honkanen, H; Herukka, SK; Remes, AM; Solje, E. 2019. Serum neurofilament light chain is a discriminative biomarker between frontotemporal lobar degeneration and primary psychiatric disorders Journal of neurology 2020; 267 1: 162-167. 2019

Jääskeläinen, O; Solje, E; Hall, A; Katisko, K; Korhonen, V; Tiainen, M; Kangas, AJ; Helisalmi, S; Pikkarainen, M; Koivisto, A; Hartikainen, P; Hiltunen, M; Ala-Korpela, M; Soininen, H; Soininen, P; Haapasalo, A; Remes, AM; Herukka, SK. 2019. Low Serum High-Density Lipoprotein Cholesterol Levels Associate with the C9orf72 Repeat Expansion in Frontotemporal Lobar Degeneration Patients Journal of Alzheimer's disease 72 1: 127-137. 2019

Jeppsson, Anna; Wikkelsö, Carsten; Blennow, Kaj; Zetterberg, Henrik; Constantinescu, Radu; Remes, Anne M; Herukka, Sanna-Kaisa; Rauramaa, Tuomas; Nagga, Katarina; Leinonen, Ville; Tullberg, Mats. 2019. CSF biomarkers distinguish idiopathic normal pressure hydrocephalus from its mimics Journal of neurology neurosurgery and psychiatry 90 10: 1117-1123. 2019

Bruun, M; Frederiksen, KS; Rhodius-Meester, HFM; Baroni, M; Gjerum, L; Koikkalainen, J; Urhemaa, T; Tolonen, A; van Gils, M; Rueckert, D; Dyremose, N; Andersen, BB; Lemstra, AW; Hallikainen, M; Kurl, S; Herukka, SK; Remes, AM; Waldemar, G; Soininen, H; Mecocci, P; et al. 2019. Impact of a clinical decision support tool on prediction of progression in early-stage dementia: a prospective validation study Alzheimer's research and therapy 11: 25. 2019

Bruun, M; Frederiksen, KS; Rhodius-Meester, HFM; Baroni, M; Gjerum, L; Koikkalainen, J; Urhema, T; Tolonen, A; van Gils, M; Tong, T; Rueckert, D; Dyremos, N; Bo Andersen, B; Simonsen, AH; Lemstra, A; Hallikainen, M; Kurl, S; Herukka, SK; Remes, AM; Waldemar, G; et al. (incl. Soininen, Hilkka). 2019. Impact of a clinical decision support tool on dementia diagnostics in memory clinics: The PredictND validation study Current alzheimer research 16 2: 91-101. 2019

Leinonen, V; Rauramaa, T; Johansson, J; Bottelbergs, A; Tesseur, I; van der Ark, P; Pemberton, D; Koivisto, AM; Jääskeläinen, JE; Hiltunen, M; Herukka, SK; Blennow, K; Zetterberg, H; Jokinen, P; Rokka, J; Helin, S; Haaparanta-Solin, M; Solin, O; Okamura, N; Kolb, HC; et al.. 2018. S-[18F]THK-5117-PET and [11C]PIB-PET Imaging in Idiopathic Normal Pressure Hydrocephalus in Relation to Confirmed Amyloid-ß Plaques and Tau in Brain Biopsies Journal of Alzheimer's Disease 64 1: 171-179. 2018

Teunissen, Charlotte E; Otto, Markus; Engelborghs, Sebastiaan; Herukka, Sanna-Kaisa; Lehmann, Sylvain; Lewczuk, Piotr; Lleó, Alberto; Perret-Liaudet, Armand; Tumani, Hayrettin; Turner, Martin R; Verbeek, Marcel M; Wiltfang, Jens; Zetterberg, Henrik; Parnetti, Lucilla; Blennow, Kaj. 2018. White paper by the Society for CSF Analysis and Clinical Neurochemistry: Overcoming barriers in biomarker development and clinical translation Alzheimer's research and therapy 10 1: 30. 2018

Oliveira, F; Leuzy, A; Castelhano, J; Chiotis, K; Hasselbalch, SG; Rinne, J; Mendonça, A; Otto, M; Lleó, A; Santana, I; Johansson, J; Anderl-Straub, S; Arnim, C; Beer, A; Blesa, R; Fortea, J; Herukka, S-K; Portelius, E; Pannee, J; Zetterberg, H; et al.. 2018. Data driven diagnostic classification in Alzheimer's disease based on different reference regions for normalization of PiB-PET images and correlation with CSF concentrations of Aß species NEUROIMAGE: CLINICAL 20: 603-610. 2018

Mattsson, N; Groot, C; Jansen, WJ; Landau, S; Villemagne, V; Engelborghs, S; Mintun, M; Lleo, A; Molinuevo, JL; Jagust, W; Frisoni, GB; Ivanoiu, A; Chételat, G; Resende de Oliveira, C; Rodrigue, KM; Kornhuber, J; Wallin, A; Klimkowicz-Mrowiec, A; Kandimella, R; Popp, J et al [Incl Herukka, Kaisa]. 2018. Prevalence of the apolipoprotein E epsilon4 allele in amyloid ß positive subjects across the spectrum of Alzheimer's disease Alzheimers and dementia 14 7: 913-924. 2018

Martiskainen, Henna; Takalo, Mari; Solomon, Alina; Stancáková, Alena; Marttinen, Mikael; Natunen, Teemu; Haapasalo, Annakaisa; Herukka, Sanna-Kaisa; Kuusisto, Johanna; Soininen, Hilkka; Kivipelto, Miia; Laakso, Markku; Hiltunen, Mikko. 2018. Decreased plasma C-reactive protein levels in APOE E 4 allele carriers Annals of Clinical and Translational Neurology 5 10: 1229-1240. 2018

Katisko, K; Solje, E; Koivisto, AM; Krüger, J; Kinnunen, T; Hartikainen, P; Helisalmi, S; Korhonen, V; Herukka, S-K; Haapasalo, A; Remes, AM. 2018. Prevalence of immunological diseases in a Finnish frontotemporal lobar degeneration cohort with the C9orf72 repeat expansion carriers and non-carriers Journal of neuroimmunology 321: 29-35. 2018

Leal, NS; Dentoni, G; Schreiner, B; Kämäräinen, OP; Partanen, N; Herukka, SK; Koivisto, AM; Hiltunen, M; Rauramaa, T; Leinonen, V; Ankarcrona, M. 2018. Alterations in mitochondria-endoplasmic reticulum connectivity in human brain biopsies from idiopathic normal pressure hydrocephalus patients Acta neuropathologica communications 6: 102. 2018

Katisko, Kasper; Kokkonen, Nina; Krüger, Johanna; Hartikainen, Päivi; Koivisto, Anne; Helisalmi, Seppo; Korhonen, Ville; Kokki, Merja; Tuusa, Jussi; Herukka, Sanna-Kaisa; Solje, Eino; Haapasalo, Annakaisa; Tasanen, Kaisa; Remes, Anne. 2018. The association between frontotemporal lobar degeneration and bullous pemphigoid Journal of Alzheimer's disease 66 2: 743-750. 2018

Katisko, Kasper; Haapasalo, Annakaisa; Koivisto, Anne; Kruger, Johanna; Hartikainen, Päivi; Korhonen, Ville; Helisalmi, Seppo; Herukka, Sanna-Kaisa; Remes, Anne M; Solje, Eino. 2018. Low Prevalence of Cancer in Patients with Frontotemporal Lobar Degeneration Journal of Alzheimer's disease 62 2: 789-794. 2018

de Matos, MR; Ferreira, C; Herukka, SK; Soininen, H; Janeiro, A; Santana, I; Baldeiras, I; Almeida, MR; Lleó, A; Dols-Icardo, O; Alcolea, D; Benussi, L; Binetti, G; Paterlini, A; Ghidoni, R; Nacmias, B; Meulenbroek, O; van Waalwijk van Doorn, LJC; Kuiperij, HB; Hausner, L; et al. 2018. Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers Journal of Alzheimer's Disease 66 2: 639-652. 2018

Haapalinna, F; Kokki, M; Jääskeläinen, O; Hallikainen, M; Helisalmi, S; Koivisto, A; Kokki, H; Paajanen, T; Penttinen, J; Pikkarainen, M; Rautiainen, M; Soininen, H; Solje, E; Remes, AM; Herukka, SK. 2018. Subtle Cognitive Impairment and Alzheimer's Disease-Type Pathological Changes in Cerebrospinal Fluid are Common Among Neurologically Healthy Subject Journal of Alzheimer's disease 62 1: 165-174. 2018

Koivisto, Anne M; Paajanen, Teemu; Rinne, Juha; Hokkanen, Laura; Vanninen, Ritva; Herukka, Sanna-Kaisa; Lötjönen, Jyrki; Hallikainen, Merja. 2018. Alzheimerin taudin varhainen tunnistaminen Duodecim 134 24: 2519-2528. 2018

Martiskainen H, Herukka SK, Stancáková A, Paananen J, Soininen H, Kuusisto J, Laakso M, Hiltunen M. 2017. Decreased plasma ß-amyloid in the Alzheimer's disease APP A673T variant carriers. ANNALS OF NEUROLOGY 82 1: 128-132. 2017

van Waalwijk van Doorn LC, Gispert JD, Kuiperij HB, Claassen, JAHR, Arighi A, Baldeiras I, Blennow K, Bozzali M, Castelo-Branco M, Cavedo E, Emek-Savas D, Eren E, Eusebi P, Farotti L, Fenoglio C, Ormaechea JF, Freund-Levi Y, Frisoni G, Galimberti D, Genc S et al. 2017. Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes. Journal of Alzheimer's Disease 56 2: 543-555. 2017

Simonsen AH, Herukka SK, Andreasen N, Baldeiras I, Bjerke M, Blennow K, Engelborghs S, Frisoni GB, Gabryelewicz T, Galluzzi S, Handels R, Kramberger MG, Kulczynska A, Molinuevo JL, Mroczko B, Nordberg A, Oliveira CR, Otto M, Rinne JO, Rot U et al.. 2017. Recommendations for CSF AD biomarkers in the diagnostic evaluation of dementia. Alzheimer's & Dementia 13 3: 274-284. 2017

Jansen WJ, Ossenkoppele R, Tijms BM, Fagan AM, Hansson O, Klunk WE, van der Flier WM, Villemagne VL, Frisoni GB, Fleisher AS, Lleó A, Mintun MA, Wallin A, Engelborghs S, Na DL, Chételat G, Molinuevo JL, Landau SM, Mattsson N, Kornhuber J et al.. 2017. Association of Cerebral Amyloid-ß Aggregation With Cognitive Functioning in Persons Without Dementia JAMA psychiatry 75 1: 84-95. 2017

Lautner R, Insel PS, Skillbäck T, Olsson B, Landén M, Frisoni GB, Herukka SK, Hampel H, Wallin A, Minthon L, Hansson O, Blennow K, Mattsson N, Zetterberg H. 2017. Preclinical effects of APOE [epsilon]4 on cerebrospinal fluid Aß42 concentrations Alzheimer's research and therapy 9 1: 87. 2017

Herukka SK, Simonsen AH, Andreasen N, Baldeiras I, Bjerke M, Blennow K, Engelborghs S, Frisoni GB, Gabryelewicz T, Galluzzi S, Handels R, Kramberger MG, Kulczynska A, Molinuevo JL, Mroczko B, Nordberg A, Oliveira CR, Otto M, Rinne JO, Rot U et al.. 2017. Recommendations for cerebrospinal fluid Alzheimer's disease biomarkers in the diagnostic evaluation of mild cognitive impairment. Alzheimer's & Dementia 13 3: 285-295. 2017

Bos I, Vos SJ, Frölich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Engelborghs S, Niemantsverdriet E, De Roeck EE, Tsolaki M, Freund-Levi Y, Johannsen P, Vandenberghe R, Lleó A, Alcolea D, Frisoni GB, Galluzzi S, Nobili F et al., the Alzheimer's Disease Neuroimaging Initiative. 2017. The frequency and influence of dementia risk factors in prodromal Alzheimer's disease. NEUROBIOLOGY OF AGING 56: 33-40. 2017

Luikku Antti J, Hall Anette, Nerg Ossi, Koivisto Anne M, Hiltunen Mikko, Helisalmi Seppo, Herukka Sanna-Kaisa, Sutela Anna, Kojoukhova Maria, Mattila Jussi, Lötjönen Jyrki, Rummukainen Jaana, Alafuzoff Irina, Jääskeläinen Juha E, Remes Anne M, Soininen Hilkka, Leinonen Ville. 2016. Multimodal analysis to predict shunt surgery outcome of 284 patients with suspected idiopathic normal pressure hydrocephalus Acta neurochirurgica 158 12: 2311-2319. 2016

Oeckl P, Jardel C, Salachas F, Lamari F, Andersen PM, Bowser R, de Carvalho M, Costa J, van Damme P, Gray E, Grosskreutz J, Hernández-Barral M, Herukka SK, Huss A, Jeromin A, Kirby J, Kuzma-Kozakiewicz M, Amador MDM, Mora JS, Morelli C et al. 2016. Multicenter validation of CSF neurofilaments as diagnostic biomarkers for ALS. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 17 5-6: 404-413. 2016

Muñoz-Ruiz MÁ, Hall A, Mattila J, Koikkalainen J, Herukka S-K, Husso M, Hänninen T, Vanninen R, Liu Y, Hallikainen M, Lötjönen J, Remes AM, Alafuzoff I, Soininen H, Hartikainen P. 2016. Using the Disease State Fingerprint Tool for Differential Diagnosis of Frontotemporal Dementia and Alzheimer's Disease. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 6 2: 313-329. 2016

Miller AM, Rutkowska A, Bahl JM, Herukka SK, Koel-Simmelink MJ, Kruse N, Mollenhauer B, Siloaho M, Skinningsrud A, Zetterberg H, Teunissen CE, Lawlor BA. 2016. Multicenter immunoassay validation of cerebrospinal fluid neurofilament light: a biomarker for neurodegeneration. Bioanalysis 8 21: 2243-2254. 2016

Halbgebauer Steffen, Nagl Magdalena, Klafki Hans, Haußmann Ute, Steinacker Petra, Oeckl Patrick, Kassubek Jan, Pinkhardt Elmar, Ludolph Albert C, Soininen Hilkka, Herukka Sanna-Kaisa, Wiltfang Jens, Otto Markus. 2016. Modified serpinA1 as risk marker for Parkinson's disease dementia: analysis of baseline data. Scientific Reports 6: 1-8. 2016

Leuzy Antoine, Chiotis Konstantinos, Hasselbalch Steen G, Rinne Juha O, de Mendonça Alexandre, Otto Markus, Lleó Alberto, Castelo-Branco Miguel, Santana Isabel, Johansson Jarkko, Anderl-Straub Sarah, von Arnim Christine AF, Beer Ambros, Blesa Rafael, Fortea Juan, Herukka Sanna-Kaisa, Portelius Erik, Pannee Josef, Zetterberg Henrik, Blennow Kaj et al. 2016. Pittsburgh compound B imaging and cerebrospinal fluid amyloid-ß in a multicentre European memory clinic study. BRAIN [ONLINE] 139 9: 2540-2553. 2016

Lelental N, Brandner S, Kofanova O, Blennow K, Zetterberg H, Andreasson U, Engelborghs S, Mroczko B, Gabryelewicz T, Teunissen C, Mollenhauer B, Parnetti L, Chiasserini D, Molinuevo JL, Perret-Liaudet A, Verbeek MM, Andreasen N, Brosseron F, Bahl JM, Herukka SK et al. 2016. Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics. Journal of Alzheimer's Disease 52 1: 51-64. 2016

Kokkonen N, Herukka SK, Huilaja L, Kokki M, Koivisto AM, Hartikainen P, Remes AM, Tasanen K. 2016. Increased Levels of the Bullous Pemphigoid BP180 Autoantibody Are Associated with More Severe Dementia in Alzheimer's Disease. JOURNAL OF INVESTIGATIVE DERMATOLOGY 2017; 137 1: 71-76. 2016

Junttila A, Kuvaja M, Hartikainen P, Siloaho M, Helisalmi S, Moilanen V, Kiviharju A, Jansson L, Tienari PJ, Remes AM, Herukka SK. 2016. Cerebrospinal Fluid TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis Patients with and without the C9ORF72 Hexanucleotide Expansion. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 6 1: 142-149. 2016

Haapalinna F, Paajanen T, Penttinen J, Kokki H, Kokki M, Koivisto AM, Hartikainen P, Solje E, Hänninen T, Remes AM, Herukka SK. 2016. Low Cerebrospinal Fluid Amyloid-Beta Concentration Is Associated with Poorer Delayed Memory Recall in Women Dementia and geriatric cognitive disorders extra 6 2: 303-312. 2016

Zwan Marissa D, Rinne Juha O, Hasselbalch Steen G, Nordberg Agneta, Lleó Alberto, Herukka Sanna-Kaisa, Soininen Hilkka, Law Ian, Bahl Justyna MC, Carter Stephen F, Fortea Juan, Blesa Rafael, Teunissen Charlotte E, Bouwman Femke H, van Berckel Bart NM, Visser Pieter J. 2015. Use of amyloid-PET to determine cutpoints for CSF markers: A multicenter study. NEUROLOGY 86 (2016) 1: 50-58. 2015

Lleó Alberto, Cavedo Enrica, Parnetti Lucilla, Vanderstichele Hugo, Herukka Sanna-Kaisa, Andreasen Niels, Ghidoni Roberta, Lewczuk Piotr, Jeromin Andreas, Winblad Bengt, Tsolaki Magda, Mroczko Barbara, Visser Pieter Jelle, Santana Isabel, Svenningsson Per, Blennow Kaj, Aarsland Dag, Molinuevo José Luis, Zetterberg Henrik, Mollenhauer Brit. 2015. Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases. Nature Reviews Neurology 11: 41-55. 2015

Vos Stephanie JB, Verhey Frans, Frölich Lutz, Kornhuber Johannes, Wiltfang Jens, Maier Wolfgang, Peters Oliver, Rüther Eckart, Nobili Flavio, Morbelli Silvia, Frisoni Giovanni B, Drzezga Alexander, Didic Mira, van Berckel Bart NM, Simmons Andrew, Soininen Hilkka, Kloszewska Iwona, Mecocci Patrizia, Tsolaki Magda, Vellas Bruno, Lovestone Simon, Muscio Cristina, Herukka Sanna-Kaisa, Salmon Eric, Bas. 2015. Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage. BRAIN 138 5: 1327-1338. 2015

Simonsen Anja Hviid, Kuiperij Bea, Ali El-Agnaf Omar Mukhtar, Engelborghs Sebastian, Herukka Sanna-Kaisa, Parnetti Lucilla, Rektorova Irena, Vanmechelen Eugeen, Kapaki Elisabeth, Verbeek Marcel, Mollenhauer Britt. 2015. The utility of alfa-synuclein as biofluid marker in neurodegenerative diseases: a systematic review of the literature. Biomarkers in Medicine [posted online August 28, 2015]: -. 2015

Martiskainen Henna, Helisalmi Seppo, Viswanathan Jayashree, Kurki Mitja, Hall Anette, Herukka Sanna-Kaisa, Sarajärvi Timo, Natunen Teemu, Kurkinen Kaisa M.A., Huovinen Jaakko, Mäkinen Petra, Laitinen Marjo, Koivisto Anne M., Mattila Kari M., Lehtimäki Terho, Remes Anne M., Leinonen Ville, Haapasalo Annakaisa, Soininen Hilkka, Hiltunen Mikko. 2015. Effects of Alzheimer's Disease-Associated Risk Loci on Cerebrospinal Fluid Biomarkers and Disease Progression: A Polygenic Risk Score Approach. Journal of Alzheimer's Disease 43 2: 565-573. 2015

Haanpää RM, Suhonen N-M, Hartikainen P, Koivisto A M, Moilanen V, Herukka S-K, Hänninen T, Remes AM. 2015. The CERAD Neuropsychological Battery in Patients with Frontotemporal Lobar Degeneration. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 5 1: 147-154. 2015

Leitão Maria João, Baldeiras Inês, Herukka Sanna-Kaisa, Pikkarainen Maria, Leinonen Ville, Simonsen Anja Hviid, Perret-Liaudet Armand, Fourier Anthony, Quadrio Isabelle, Veiga Pedro Mota, de Oliveira Catarina Resende. 2015. Chasing the effects of pre-analytical confounders - a multicenter study on CSF-AD biomarkers. Frontiers in Neurology 6: 153. 2015

Jansen WJ, Ossenkoppele R, Knol DL, Tijms BM, Scheltens P, Verhey FR, Visser PJ; Amyloid Biomarker Study Group, Aalten P, Aarsland D, Alcolea D, Alexander M, Almdahl IS, Arnold SE, Baldeiras I, Barthel H, van Berckel BN, Bibeau K, Blennow K, Brooks DJ, van Buchem MA, Camus V, Cavedo E, Chen K, Chetelat G, Cohen AD, Drzezga A, Engelborghs S, Fagan AM, Fladby T, Fleisher AS, van der Flier WM, Ford L. 2015. Prevalence of Cerebral Amyloid Pathology in Persons Without Dementia A Meta-analysis. JAMA - JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 313 19: 1924-1938. 2015

Herukka Sanna-Kaisa, Rummukainen Jaana, Ihalainen Jouni, von und zu Fraunberg Mikael, Koivisto Anne M, Nerg Ossi, Puli Lakshman K, Seppälä Toni T, Zetterberg Henrik, Pyykkö Okko T, Helisalmi Seppo, Tanila Heikki, Alafuzoff Irina, Hiltunen Mikko, Rinne Jaakko, Soininen Hilkka, Jääskeläinen Juha E, Leinonen Ville. 2015. Amyloid-ß and Tau Dynamics in Human Brain Interstitial Fluid in Patients with Suspected Normal Pressure Hydrocephalus. Journal of Alzheimer's Disease 46 1: 261-269. 2015

Herukka Sanna-Kaisa, Remes Anne. 2015. Laboratoriotutkimukset. Teoksessa: Timo Erkinjuntti, Anne Remes, Juha Rinne, Hilkka Soininen (toim.) Muistisairaudet. KUSTANNUS OY DUODECIM. s. 355-359. 2015

Ewers Michael, Mattsson Niklas, Minthon Lennart, Molinuevo José L, Antonell Anna, Popp Julius, Jessen Frank, Herukka Sanna-Kaisa, Soininen Hilkka, Maetzler Walter, Leyhe Thomas, Bürger Katharina, Taniguchi Miyako, Urakami Katsuya, Lista Simone, Dubois Bruno, Blennow Kaj, Hampel Harald. 2015. CSF biomarkers for the differential diagnosis of Alzheimer's disease. A large-scale international multicenter study. Alzheimer's & Dementia 11 11: 1306-1315. 2015

Kämäläinen A, Herukka S-K, Hartikainen P, Helisalmi S, Moilanen V, Knuuttila A, Jansson L, Tienari PJ, Remes AM. 2015. Cerebrospinal Fluid Biomarkers for Alzheimer's Disease in Patients with Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis with the C9ORF72 Repeat Expansion. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 39 5-6: 287-293. 2015

Portelius Erik, Soininen Hilkka, Andreasson Ulf, Zetterberg Henrik, Persson Rita, Karlsson Gösta, Blennow Kaj, Herukka Sanna-Kaisa, Mattsson Niklas. 2014. Exploring Alzheimer Molecular Pathology in Down's Syndrome Cerebrospinal Fluid. NEURODEGENERATIVE DISEASES 14 2: 98-106. 2014

Pyykkö OT, Lumela M, Rummukainen J, Nerg O, Seppälä TT, Herukka SK, Koivisto AM, Alafuzoff I, Puli L, Savolainen S, Soininen H, Jääskeläinen JE, Hiltunen M, Zetterberg H, Leinonen V. 2014. Cerebrospinal Fluid Biomarker and Brain Biopsy Findings in Idiopathic Normal Pressure Hydrocephalus. PLOS ONE [ONLINE] 9 3; e91974: 1-10. 2014

Yang Hongqian, Lyutvinskiy Yaroslav, Herukka Sanna-Kaisa, Soininen Hilkka, Rutishauser Dorothea, Zubarev Roman A. 2014. Prognostic polypeptide blood plasma biomarkers of Alzheimer's Disease progression. Journal of Alzheimer's Disease 40: 659-666. 2014

Portelius Erik, Hölttä Mikko, Soininen Hilkka, Bjerke Maria, Zetterberg Henrik, Westerlund Anni, Herukka Sanna-Kaisa, Blennow Kaj, Mattsson Niklas. 2014. Altered cerebrospinal fluid levels of amyloid beeta and amyloid precursor-like protein 1 peptides in Down's Syndrome. NEUROMOLECULAR MEDICINE 16 2: 510-516. 2014

Lautner R, Palmqvist S, Mattsson N, Andreasson U, Wallin A, Pålsson E, Jakobsson J, Herukka SK, Owenius R, Olsson B, Hampel H, Rujescu D, Ewers M, Landén M, Minthon L, Blennow K, Zetterberg H0, Hansson O; Alzheimer's Disease Neuroimaging Initiative. 2014. Apolipoprotein E Genotype and the Diagnostic Accuracy of Cerebrospinal Fluid Biomarkers for Alzheimer Disease. JAMA Psychiatry 71 10: 1183-1191. 2014

Helisalmi S, Hall A, Meriläinen EH, Väisänen V, Koivisto AM, Herukka SK, Laitinen M, Soininen H, Hiltunen M. 2014. The Effect of TOMM40 Poly-T Repeat Lengths on Age of Onset and Cerebrospinal Fluid Biomarkers in Finnish Alzheimer's Disease Patients. NEURODEGENERATIVE DISEASES 14 4 (Online First Articles): 204-208. 2014

Duits FH, Teunissen CE, Bouwman FH, Visser PJ, Mattsson N, Zetterberg H, Blennow K, Hansson O, Minthon L, Andreasen N, Marcusson J, Wallin A, Rikkert MO, Tsolaki M, Parnetti L, Herukka SK, Hampel H, De Leon MJ, Schröder J, Aarsland D, Blankenstein MA, Scheltens P, van der Flier WM. 2014. The cerebrospinal fluid "Alzheimer profile": Easily said, but what does it mean?. Alzheimer's & Dementia 10 6: 713-723. 2014

Andreasson U, Lautner R, Schott JM, Mattson N, Hansson P, Herukka S-K, Helisalmi S, Ewers M, Hampel H, Wallin A, Minthon L, Hardy J, Blennow K, Zetterberg H. 2013. CSF biomarkers for Alzheimer's pathology and the effect size of APOE epsilon4. MOLECULAR PSYCHIATRY [Epub ahead of print]: 1-2. 2013

Elias-Sonnenschein LS, Helisalmi S, Natunen T, Hall A, Paajanen T, Herukka S-K, Laitinen M, Remes AM, Koivisto AM, Mattila KM, Lehtimäki T, Verhey FRJ, Visser PJ, Soininen H, Hiltunen M. 2013. Genetic loci associated with Alzheimer's Disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort. PLOS ONE [ONLINE] 8 4: e59676. 2013

Kämäläinen A, Viswanathan J, Natunen T, Helisalmi S, Kauppinen T, Pikkarainen M, Pursiheimo J-P, Alafuzoff I, Kivipelto M, Haapasalo A, Soininen H, Herukka S-K, Hiltunen M. 2013. GRN variant rs5848 reduces plasma and brain levels of granulin in Alzheimer's disease patients. Journal of Alzheimer's Disease 33: 23-27. 2013

Liu Y, Mattila J, Muñoz Ruiz MA, Paajanen T, Koikkalainen J, van Gils M, Herukka S-K, Waldemar G, Lötjönen J, Soininen H. 2013. Predicting AD conversion: Comparison between prodromal AD guidelines and computer assisted PredictAD tool. PLOS ONE [ONLINE] 8 2: e55246. 2013

Lundström SL, Yang H, Lyutvinskiy Y, Rutishauser D, Herukka SK, Soininen H, Zubarev RA. 2013. Blood plasma IgG Fc glycans are significantly altered in Alzheimer's Disease and progressive mild cognitive impairment. Journal of Alzheimer's Disease [Epub ahead of print]: -. 2013

Muñoz-Ruiz MA, Hall A, Mattila J, Koikkalainen J, Herukka SK, Vanninen R, Liu Y, Lötjönen J, Soininen H. 2013. Comparing Predictors of Conversion to Alzheimer's Disease Using the Disease State Index. NEURODEGENERATIVE DISEASES epub ahead of print: 3 sivua. 2013

Munoz-Ruiz MA, Hartikainen P, Hall A, Mattila J, Koikkalainen J, Herukka S-K, Julkunen V, Vanninen R, Liu Y, Lötjönen J, Soininen H. 2013. Disease state fingerprint in frontotemporal degeneration with reference to Alzheimer's Disease and mild cognitive impairment. Journal of Alzheimer's Disease 35: 727-739. 2013

Seppälä T, Herukka S-K, Remes AM. 2013. Alzheimerin taudin varhaisdiagnostiikka. DUODECIM 129: 2003-2010. 2013

Seppälä TT, Louhija UM, Appelberg B, Herukka SK, Juva K. 2013. Comparison between clinical diagnosis and CSF biomarkers of Alzheimer Disease in elderly patients with late onset psychosis: Helsinki old age psychosis study (HOPS). AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY [Epub ahead of print]: -. 2013

Zetterberg H, Lunn MP, Herukka S-K. 2012. Clinical use of CSF biomarkers in Alzheimer's disease. Biomarkers in Medicine 6 4: 371-376. 2012

Simonsen AH, Mattila J, Hejl A-M, Frederiksen KS, Herukka S-K, Hallikainen M, van Gils M, Lötjönen J, Soininen H, Waldemar G. 2012. Application of the PredictAD software tool to predict progression in patients with mild cognitive impairment. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 34: 344-350. 2012

Seppälä TT, Nerg O, Koivisto AM, Rummukainen J, Puli L, Zetterberg H, Pyykkö OT, Helisalmi S, Alafuzoff I, Hiltunen M, Jääskeläinen JE, Rinne J, Soininen H, Leinonen V, Herukka S-K. 2012. CSF biomarkers for Alzheimer disease correlate with cortical brain biopsy findings NEUROLOGY 78: 1568-1575. 2012

Natunen T, Helisalmi S, Vepsäläinen S, Sarajärvi T, Antikainen L, Mäkinen P, Herukka S-K, Koivisto AM, Haapasalo A, Soininen H, Hiltunen M. 2012. Genetic analysis of genes involved in amyloid-beta degradation and clearance in Alzheimer's Disease Journal of Alzheimer's Disease 28: 553-559. 2012

Munoz-Ruiz MA, Hartikainen P, Koikkalainen J, Wolz R, Julkunen V, Niskanen E, Herukka S-K, Kivipelto M, Vanninen R, Rueckert D, Liu Y, Lötjönen J, Soininen H. 2012. Structural MRI in frontotemporal dementia: Comparisons between hippocampal volumetry, tensor-based morphometry and voxel-based morphometry PLoS ONE 7 12: e52531. 2012

Lehnert S, Jesse S, Rist W, Steinacker P, Soininen H, Herukka S-K, Tumani H, Lenter M, Oeckl P, Ferger B, Hengerer B, Otto M. 2012. iTRAQ and multiple reaction monitoring as proteomic tools for biomarker search in cerebrospinal fluid of patients with Parkinson's disease dementia EXPERIMENTAL NEUROLOGY 234: 499-505. 2012

Jesse S, Lehnert S, Jahn O, Parnetti L, Soininen H, Herukka S-K, Steinacker P, Tawfik S, Tumani H, von Arnim CSF, Neumann M, Kretzschmar HA, Kulaksiz H, Lenter M, Wiltfang J, Ferger B, Hengerer B, Otto M. 2012. Differential sialylation of serpin A1 in the early diagnosis of Parkinson's Disease Dementia. PLOS ONE [ONLINE] 7 11: e48783. 2012

Hallikainen I, Koivisto AM, Paajanen T, Hiltunen A, Karppi P, Vanhanen M, Välimäki T, Herukka S-K, Soininen H, Hänninen T. 2012. Cognitive and neuropsychiatric symptom differences in early stages of Alzheimer's Disease: Kuopio ALSOVA Study DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 2: 209-218. 2012

Mattson N, Rosen E, Hansson O, Andreasen N, Parnetti L, Jonsson M, Herukka S-K, van der Flier WM, Blankenstein MA, Ewers M, Rich K, Kaiser E, Verbeek MM, Olde Rikkert M, Tsolaki M, Mulugeta E, Aarsland D, Visser PJ, Schröder J, Marcusson J, de Leon M, Hampel H, Scheltens P, Wallin A, Eriksdotter-Jönhagen M, Minthon L, Winblad B, Blennow K, Zetterberg H. 2012. Age and diagnostic performance of Alzheimer disease CSF biomarkers NEUROLOGY 78: 468-476. 2012

Casarotto S, Määttä S, Herukka SK, Pigorini A, Napolitani M, Gosseries O, Niskanen E, Könönen M, Mervaala E, Rosanova M, Soininen H, Massimini M. 2011. Transcranial magnetic stimulation-evoked EEG/cortical potentials in physiological and pathological aging. NEUROREPORT 22 12: 592-597. 2011

Mattson N, Andreasson U, Persson S, Arai H, Dev Batish S, Bernardini S, Bocchio-Chiavetto L, Blankenstein MA, Carrillo MC, Chalbot S, Coart E, Chiasserini D, Cutler N, Dahlbors G, Duller S, Fagan AM, Forlenza O, Frisoni GB, Galasko D, Galimberti D, Hampel H, Handberg A, Heneka MT, Herskovits AZ, Herukka S-K. 2011. The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers Alzheimer's & Dementia 7: 386-395. 2011

Oresic M, Hyötyläinen T, Herukka S-K, Sysi-Aho M, Mattila I, Seppänan-Laakso T, Julkunen V, Gopalacharyulu PV, Hallikainen M, Koikkalainen J, Kivipelto M, Helisalmi S, Lötjönen J, Soininen H. 2011. Metabolome in progression to Alzheimer's disease Translational Psychiatry 1: e57. 2011

Seppälä TT, Koivisto AM, Hartikainen P, Helisalmi S, Soininen H, Herukka S-K. 2011. Longitudinal changes of CSF biomarkers in Alzheimer's Disease. Journal of Alzheimer's Disease 25: 583-594. 2011

Spitzer P, Schieb H, Kamrowski-Kruck H, Otto M, Chiasserini D, Parnetti L, Herukka S-K, Schuchhardt J, Wiltfang J, Klafki H-W. 2011. Evidence for elevated cerebrospinal fluid ERK1/2 levels in Alzheimer Dementia International Journal of Alzheimer's Disease 2011 ID 739847: 1-9. 2011

Seppälä TT, Herukka SK, Hänninen T, Tervo S, Hallikainen M, Soininen H & Pirttilä T. 2010. Plasma A-beta42 and A-beta40 as markers of cognitive change in follow-up: a prospective, longitudinal, population-based cohort study. JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY 81: 1123-1127. 2010

Spitzer P, Klafki HW, Blennow K, Buee L, Esselmann H, Herukka SK, Jimenez C, Klivenyi P, Lewczuk P, Maler JM et al. 2010. cNEUPRO: Novel biomarkers for neurodegenerative diseases. International Journal of Alzheimer's Disease ID548145: 1-12. 2010

Sarajärvi T, Helisalmi S, Antikainen L, Mäkinen P, Koivisto AM, Herukka SK, Haapasalo A, Soininen H, Hiltunen M. 2010. An association study of 21 potential Alzheimer's disease risk genes in a Finnish population. Journal of Alzheimer's Disease 21 3: 763-767. 2010

Petzold A, Altintas A, Andreoni L, Bartos A, Berthele A, Blankenstein MA, Buee L, Castellazzi M, Cepok S & Comabella M. 2010. Neurofilament ELISA validation JOURNAL OF IMMUNOLOGICAL METHODS 352: 23-31. 2010

Julkunen V, Niskanen E, Koikkalainen J, Herukka SK, Pihlajamäki M, Hallikainen H, Kivipelto M, Muehlboeck S, Evans AC, Vanninen R & Soininen H. 2010. Differences in cortical thickness in healthy controls, subjects with mild cognitive impairment, and Alzheimer's Diseaes patients: A longitudinal study. Journal of Alzheimer's Disease 21: 1141-1151. 2010

Mattsson N, Hansson O, Andreasen N, Parnetti L, Johnsson M, Herukka SK, van der Flier WM..., Marcusson J, de LEON M, Hampel H, Scheltens P, Pirttilä T, Wallin A, Eriksdotter Jönhagen M, Minthon L, Winblad B, Blennow K, Pirttilä T. 2009. CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. JAMA - JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 302 4: 385-393. 2009

Ojala J, Alafuzoff I, Herukka SK, van Groen T, Tanila H, Pirttilä T, Pirttilä T. 2009. Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients. NEUROBIOLOGY OF AGING 30: 198-209. 2009

Tapiola T, Alafuzoff I, Herukka S-K, Parkkinen L, Hartikainen P, Soininen H, Pirttilä T, Soininen H, Pirttilä T. 2009. Cerebrospinal fluid {beta}-amyloid 42 and Tau proteins as biomarkers of Alzheimer-type pathologic changes in the brain. ARCHIVES OF NEUROLOGY 66 3: 382-389. 2009

Lämsä R, Helisalmi S, Herukka S-K, Tapiola T, Pirttilä T, Vepsäläinen S, Hiltunen M, Soininen H, Pirttilä T, Soininen H. 2008. Genetic study evaluating LDLR polymorphisms and Alzheimer's disease NEUROBIOLOGY OF AGING 29: 848-855. 2008

Koivunen J, Pirttilä T, Kemppainen N, Aalto S, Herukka S-K, Jauhiainen AM, Hänninen T, Hallikainen M, Någren K, Rinne JO, Soininen H, Pirttilä T, Soininen H. 2008. PET amyloid ligand (11C)PIB uptake and cerebrospinal fluid beta-amyloid in mild cognitive impairment. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 26: 378-383. 2008

Herukka S-K, Pennanen C, Soininen H, Pirttilä T, Soininen H, Pirttilä T. 2008. CSF Abeeta42, tau and phosphorylated tau correlate with medial temporal lobe atrophy. Journal of Alzheimer's Disease 14: 51-57. 2008

Herukka S-K, Helisalmi S, Hallikainen M, Tervo S, Soininen H, Pirttilä T, Herukka S-K, Helisalmi S, Hallikainen M, Tervo S, Soininen H, Pirttilä T. 2007. CSF Abeta42, tau and phosphorylated tau, APOE epsilon4 allele and MCI type in progressive MCI NEUROBIOLOGY OF AGING 28: 507-514. 2007

Herukka SK. 2007. Usefulness of Cerebrospinal Fluid Biomarkers in Diagnosis of Early Alzheimer's Disease. Kuopion yliopisto. Neurologian klinikan julkaisusarja, No. 2007

Lämsä R, Helisalmi S, Herukka S-K, Tapiola T, Pirttilä T, Vepsäläinen S, Hiltunen M, Soininen H, Lämsä R, Helisalmi S, Herukka S-K, Pirttilä T, Vepsäläinen S, Hiltunen M, Soininen H. 2007. Study on the association between SOAT1 polymorphisms, Alzheimer's disease risk and the level of CSF biomarkers. DEMENTIA AND GERIATRIC COGNITIVE DISORDERS 24: 146-150. 2007

Lämsä R, Helisalmi S, Hiltunen M, Herukka S-K, Tapiola T, Pirttilä T, Vepsäläinen S, Soininen H, Soininen H, Lämsä R, Helisalmi S, Herukka S-K, Pirttilä T, Vepsäläinen S. 2007. The association study between DHCR24 polymorphisms and Alzheimer's disease. AMERICAN JOURNAL OF MEDICAL GENETICS. PART B. NEUROPSYCHIATRIC GENETICS 144B: 906-910. 2007

Herukka S-K, Hallikainen M, Tervo S, Helisalmi S, Tapiola T, Soininen H, Pirttilä T, Hallikainen M, Tervo S, Helisalmi S, Soininen H, Pirttilä T. 2006. Cerebrospinal fluid Abeta42, tau and phosphorylated tau predict progression in patients with cognitive impairment: Vellas B, Winblad B, Grundman M, Fitten LJ, Feldman H, Giacobini E, Kurz A, Research and Practice in Alzheimer¿s Disease.Serdi. 245-250. 2006

Herukka S-K, Hallikainen M, Soininen H, Pirttilä T, Hallikainen M, Soininen H, Pirttilä T. 2005. CSF Abeta42 and tau or phosphorylated tau and prediction of progressive mild cognitive impairment. NEUROLOGY 64: 1294-1297. 2005

Liu L, Herukka S-K, Minkeviciene R, van Groen T, Tanila H. 2004. Longitudinal observation on CSF Abeta42 levels in young to middle-aged amyloid precursor protein/presenilin-1 doubly transgenic mice. NEUROBIOLOGY OF DISEASE (SAN DIEGO CA) 17: 516-523. 2004

Liu L, Tapiola T, Herukka S-K, Heikkilä M, Tanila H. 2003. Abeta levels in serum, CSF and brain, and cognitive deficits in APP + PS1 transgenic mice. NEUROREPORT 14 1: 163-166. 2003

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