Vesa-Pekka Lehto

Haluska, Ondřej; Rahmani, Arezoo; Salami, Ayobami; Turhanen, Petri; Vepsäläinen, Jouko; Lappalainen, Reijo; Lehto, Vesa-Pekka; Riikonen, Joakim. 2021. Plant-based nanostructured silicon carbide modified with bisphosphonates for metal adsorption Microporous and mesoporous materials 324: 111294. 2021

Liu, Lizhi; Bai, Xuan; Martikainen, Maria-Viola; Kårlund, Anna; Roponen, Marjut; Xu, Wujun; Hu, Guoqing; Tasciotti, Ennio; Lehto, Vesa-Pekka. 2021. Cell membrane coating integrity affects the internalization mechanism of biomimetic nanoparticles Nature communications 12 1: 5726. 2021

Methods for synthesis of nanobiopolymers. Iftekhar, Sidra; Wasayh, Muhammad Abdul; Asif, Muhammad Bilal; Lehto, Vesa-Pekka; Sillanpää, Mika / Biopolymeric Nanomaterials: Fundamentals and Applications. A volume in Micro and Nano Technologies. 2021. 2021

Polysaccharide-derived biopolymeric nanomaterials for wastewater treatment. Asif, Muhammad Bilal; Zhang, Zhenghua; Iftekhar, Sidra; Lehto, Vesa-Pekka / Biopolymeric Nanomaterials: Fundamentals and Applications. A volume in Micro and Nano Technologies. 2021. 2021

Tamarov, K; Wang, JT; Kari, J; Happonen, E; Vesavaara, I; Niemelä, M; Perämäki, P; Al-Jamal, KT; Xu, W; Lehto, VP. 2021. Comparison between Fluorescence Imaging and Elemental Analysis to Determine Biodistribution of Inorganic Nanoparticles with Strong Light Absorption Acs applied materials and interfaces 13 34: 10392-40400. 2021

Thapa, Rinez; Mondal, Subhasish; Riikonen, Joakim; Rantanen, Jimi; Näkki, Simo; Nissinen, Tuomo; Närvänen, Ale; Lehto, Vesa-Pekka. 2021. Biogenic nanoporous silicon carrier improves the efficacy of buparvaquone against resistant visceral leishmaniasis PLoS neglected tropical diseases 15 6: e0009533. 2021

Thapa, Rinez; Rahmani, Arezoo; Turhanen, Petri; Taskinen, Antti; Nissinen, Tuomo; Neitola, Raisa; Vepsäläinen, Jouko; Lehto, Vesa-Pekka; Riikonen, Joakim. 2021. Recovery of uranium with bisphosphonate modified mesoporous silicon Separation and purification technology 272: 118913. 2021

Valkama, Eetu; Haluska, Ondrej; Lehto, Vesa-Pekka; Korhonen, Ossi; Pajula, Katja. 2021. Production and Stability of Amorphous Solid Dispersions Produced by a Freeze-drying Method from DMSO International journal of pharmaceutics 606: 120902. 2021

Kamakura, Remi; Raza, Ghulam Shere; Mäkila, Ermei; Riikonen, Joakim; Kovalainen, Miia; Ueta, Yoichi; Lehto, Vesa-Pekka; Salonen, Jarno; Herzig, Karl-Heinz. 2021. Colonic Delivery of alpha-Linolenic Acid by an Advanced Nutrient Delivery System Prolongs Glucagon-Like Peptide-1 Secretion and Inhibits Food Intake in Mice Molecular nutrition and food research [ePub ahead of print 19 Dec 2021]: 2100978. 2021

Tamarov, Konstantin; Kiviluoto, Riku; Swanson, Joseph D; Unger, Bret A; Ernst, Alexis T; Aindow, Mark; Riikonen, Joakim; Lehto, Vesa-Pekka; Kolasinski, Kurt W. 2020. Low-Load Metal-Assisted Catalytic Etching Produces Scalable Porosity in Si Powders Acs applied materials and interfaces 12: 48969-48981. 2020

Zhao, Xiuyun; Lehto, Vesa-Pekka. 2020. Challenges and prospects of nanosized silicon anodes in lithium-ion batteries Nanotechnology 32 4: 042002. 2020

Xu, Wujun; Cui, Pang; Happonen, Emilia; Leppänen, Jukka; Liu, Lizhi; Rantanen, Jimi; Majda, Dorota; Saukko, Annina; Thapa, Rinez; Nissinen, Tuomo; Tynkkynen, Tuulia; Töyräs, Juha; Fan, Li; Liu, Wenchao; Lehto, Vesa-Pekka. 2020. Tailored Synthesis of PEGylated Bismuth Nanoparticles for X-ray Computed Tomography and Photothermal Therapy: One-Pot, Targeted Pyrolysis, and Self-Promotion Acs applied materials and interfaces 12 42: 47233-47244. 2020

Xu, Wu jun; Leskinen, Jarkko; Tick, Jenni; Happonen, Emilia; Tarvainen, Tanja; Lehto, Vesa-Pekka. 2020. Black Mesoporous Silicon as a Contrast Agent for LED-Based 3D Photoacoustic Tomography Acs applied materials and interfaces 12 5: 5456-5461. 2020

Wen, Huang; Tamarov, Konstantin; Happonen, Emilia; Lehto, Vesa-Pekka; Xu, Wujun. 2020. Inorganic Nanomaterials for Photothermal-Based Cancer Theranostics Advanced therapeutics 2021; 4 2: 2000207. 2020

Tamarov, Konstantin; Swanson, Joseph D; Unger, Bret A; Kolasinski, Kurt W; Ernst, Alexis T; Aindow, Mark; Lehto, Vesa-Pekka; Riikonen, Joakim. 2020. Controlling the Nature of Etched Si Nanostructures: High- versus Low-Load Metal-Assisted Catalytic Etching (MACE) of Si Powders Acs applied materials and interfaces 12 4: 4787-4796. 2020

Liu, Lizhi; Chen, Sheng; Zhang, Xu; Xue, Zhenjie; Cui, Shengjie; Hua, Xiaoting; Yang, Baowei; Yan, Huiling; Liu, Cong; Wang, Jing; Zhang, Zengfeng; Yu, Wei; Wu, Fan; Xu, Wujun; Lehto, Vesa-Pekka; Yue, Tianli; Liu, Yan; Yu, Yunsong; Wang, Tie; Wang, Jianlong. 2020. Mechanical penetration of ß-lactam-resistant Gram-negative bacteria by programmable nanowires Science advances 6 27: eabb9593. 2020

Riikonen, Joakim; Rantanen, Jimi; Thapa, Rinez; Le, Nguyen T; Rigolet, Severinne; Fioux, Philippe; Turhanen, Petri; Bodiford, Nelli K; Kalluri, Jhansi R; lkonen, Timo; Nissinen, Tuomo; Lebeau, Benedicte; Vepsäläinen, Jouko; Coffer, Jeffery L; Lehto, Vesa-Pekka. 2020. Rapid synthesis of nanostructured porous silicon carbide from biogenic silica Journal of the American Ceramic Society 2021; 104 2: 766-775. 2020

Riikonen, Joakim; Nissinen, Tuomo; Alanne, Aino; Thapa, Rinez; Fioux, Philippe; Bonne, Magali; Rigolet, Severinne; Morlet-Savary, Fabrice; Aussenac, Fabien; Marichal, Claire; Lalevee, Jacques; Vepsäläinen, Jouko J; Lebeau, Benedicte; Lehto, Vesa-Pekka. 2020. Stable surface functionalization of carbonized mesoporous silicon Inorganic chemistry frontiers 6 3: 631-641. 2020

Lähde, Anna; Haluska, Ondrej; Alatalo, Sara-Maaria; Sippula, Olli; Mešceriakovas, Arunas; Lappalainen, Reijo; Nissinen, Tuomo; Riikonen, Joakim; Lehto, Vesa-Pekka. 2020. Synthesis of graphene-like carbon from agricultural side stream with magnesiothermic reduction coupled with atmospheric pressure induction annealing Nano Express 1 1: 010014. 2020

Kalidas, N; Riikonen, J; Xu, W; Lahtinen, K; Kallio, T; Lehto, VP. 2020. Cascading use of barley husk ash to produce silicon for composite anodes of Li-ion batteries Materials chemistry and physics 245: 122736. 2020

Ikonen, Timo; Kalidas, Nathiya; Lahtinen, Katja; Isoniemi, Tommi; Toppari, Jussi; Vázquez, Ester; Herrero-Chamorro, Antonia; Fierro, José Luis; Kallio, Tanja; Lehto, Vesa-Pekka. 2020. Conjugation with carbon nanotubes improves the performance of mesoporous silicon as Li-ion battery anode Scientific reports 10: 5589. 2020

Happonen, Emilia; Tamarov, Konstantin; Martikainen, Maria-Viola; Ketola, Kirsi; Roponen, Marjut; Lehto, Vesa-Pekka; Xu, Wujun. 2020. Thermal dose as a universal tool to evaluate nanoparticle-induced photothermal therapy International journal of pharmaceutics 587: 119657. 2020

Soikkeli, Maiju; Kettunen, Mikko I; Nivajärvi, Riikka; Olsson, Venla; Rönkkö, Seppo; Laakkonen, Johanna P; Lehto, Vesa-Pekka; Kavakka, Jari; Heikkinen, Sami. 2019. Assessment of the Relaxation-Enhancing Properties of a Nitroxide-Based Contrast Agent TEEPO-Glc with In Vivo Magnetic Resonance Imaging Contrast media and molecular imaging 2019: 5629597. 2019

Thapa, Rinez; Nissinen, Tuomo; Turhanen, Petri; Määttä, Juha; Vepsäläinen, Jouko; Lehto, Vesa-Pekka; Riikonen, Joakim. 2019. Bisphosphonate modified mesoporous silicon for scandium adsorption Microporous and mesoporous materials 2020; 296: 109980. 2019

Sviridov, Andrey; Tamarov, Konstantin; Fesenko, Ivan; Xu, Wujun; Andreev, Valery; Timoshenko, Victor; Lehto, Vesa-Pekka. 2019. Cavitation Induced by Janus-Like Mesoporous Silicon Nanoparticles Enhances Ultrasound Hyperthermia Frontiers in chemistry 7: 393. 2019

Lumen, D; Näkki, S; Imlimthan, S; Lambidis, E; Sarparanta, M; Xu, W; Lehto, VP; Airaksinen, AJ. 2019. Site-Specific 111In-Radiolabeling of Dual-PEGylated Porous Silicon Nanoparticles and Their In Vivo Evaluation in Murine 4T1 Breast Cancer Model Pharmaceutics 11 12: 686. 2019

Rantanen, Jimi; Majda, Dorota; Riikonen, Joakim; Lehto, Vesa-Pekka. 2019. The atomic local ordering of SBA-15 studied with pair distribution function analysis, and its relationship to porous structure and thermal stability Acta materialia 175: 341-347. 2019

Kamakura, R; Kovalainen, M; Riikonen, J; Nissinen, T; Shere Raza, G; Walkowiak, J; Lehto, VP; Herzig, KH. 2019. Inorganic mesoporous particles for controlled α-linolenic acid delivery to stimulate GLP-1 secretion in vitro European journal of pharmaceutics and biopharmaceutics 144: 132-138. 2019

Honkanen, MKM; Saukko, AEA; Turunen, MJ; Xu, W; Lovric, G; Honkanen, JTJ; Grinstaff, MW; Lehto, VP; Töyräs, J. 2019. Triple Contrast CT Method Enables Simultaneous Evaluation of Articular Cartilage Composition and Segmentation Annals of biomedical engineering 2020; 48 2: 556-567. 2019

Näkki, S; Wang, JT; Wu, J; Fan, L; Rantanen, J; Nissinen, T; Kettunen, MI; Backholm, M; Ras, RHA; Al-Jamal, KT; Lehto, VP; Xu, W. 2018. Designed inorganic porous nanovector with controlled release and MRI features for safe administration of doxorubicin INTERNATIONAL JOURNAL OF PHARMACEUTICS 2019; 554: 327-336. 2018

Tamarov, Konstantin; Näkki, Simo; Xu, Wujun; Lehto, Vesa-Pekka. 2018. Approaches to improve the biocompatibility and systemic circulation of inorganic porous nanoparticles Journal of Materials Chemistry B 6 22: 3632-3649. 2018

Xu, Wujun; Tamarov, Konstantin; Fan, Li; Granroth, Sari; Rantanen, Jimi; Nissinen, Tuomo; Peraniemi, Sirpa; Uski, Oskari; Hirvonen, Maija-Riitta; Lehto, Vesa-Pekka. 2018. Scalable Synthesis of Biodegradable Black Mesoporous Silicon Nanoparticles for Highly Efficient Photothermal Therapy ACS Applied Materials & Interfaces 10 28: 23529-23538. 2018

Näkki Simo, Martinez Jonathan O, Evangelopoulos Michael, Xu Wujun, Lehto Vesa-Pekka, Tasciotti Ennio. 2017. Chlorin e6 Functionalized Theranostic Multistage Nanovectors Transported by Stem Cells for Effective Photodynamic Therapy ACS Applied Materials & Interfaces 9 28: 23441-23449. 2017

Tamarov K, Sviridov A, Xu WJ, Malo M, Andreev V, Timoshenko V, Lehto VP. 2017. Nano Air Seeds Trapped in Mesoporous Janus Nanoparticles Facilitate Cavitation and Enhance Ultrasound Imaging. ACS Applied Materials & Interfaces 9 40: 35234-35243. 2017

Saukko Annina EA, Honkanen Juuso TJ, Xu Wujun, Väänänen Sami P, Jurvelin Jukka S, Lehto Vesa-Pekka, Töyräs Juha. 2017. Dual Contrast CT Method Enables Diagnostics of Cartilage Injuries and Degeneration Using a Single CT Image. ANNALS OF BIOMEDICAL ENGINEERING 45 12: 2857-2866. 2017

Riikonen, Joakim; Xu, Wujun; Lehto, Vesa-Pekka. 2017. Mesoporous systems for poorly soluble drugs - recent trends INTERNATIONAL JOURNAL OF PHARMACEUTICS 2018; 536 1: 178-186. 2017

Majda D, Bhattarai A, Riikonen J, Napruszewska BD, Zimowska M, Michalik-Zym A, Töyräs J, Lehto V-P. 2017. New approach for determining cartilage pore size distribution: NaCl-thermoporometry. Microporous and Mesoporous Materials 241: 238-245. 2017

Kovalainen M, Kamakura R, Riikonen J, Finnilä M, Nissinen T, Rantanen J, Niemelä M, Perämäki P, Mäkinen M, Herzig KH, Lehto VP. 2017. Biodegradation of inorganic drug delivery systems in subcutaneous conditions. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 2018; 122: 113-125. 2017

Ikonen T, Nissinen T, Pohjalainen E, Sorsa O, Kallio T, Lehto V -P. 2017. Electrochemically anodized porous silicon: Towards simple and affordable anode material for Li-ion batteries. Scientific Reports 7: 7880. 2017

Drobczynski Slawomir, Prorok Katarzyna, Tamarov Konstantin, Dus-Szachniewicz Kamila, Lehto Vesa-Pekka, Bednarkiewicz Artur. 2017. Toward Controlled Photothermal Treatment of Single Cell: Optically Induced Heating and Remote Temperature Monitoring In Vitro through Double Wavelength Optical Tweezers. ACS Photonics 4 8: 1993-2002. 2017

Hafshejani LD, Tangsir S, Koponen H, Riikonen J, Karhunen T, Tapper U, Lehto V-P, Moazed H, Naseri AA, Hooshmand A, Jokiniemi J, Bhatnagar A, Lähde A. 2016. Synthesis and characterization of Al2O3 nanoparticles by flame spray pyrolysis (FSP) - Role of Fe ions in the precursor. POWDER TECHNOLOGY 298: 42-49. 2016

Nissinen Tuomo, Ikonen Timo, Lama Mejor, Riikonen Joakim, Lehto Vesa-Pekka. 2016. Improved production efficiency of mesoporous silicon nanoparticles by pulsed electrochemical etching. POWDER TECHNOLOGY 288: 360-365. 2016

Nissinen Tuomo, Näkki Simo, Laakso Hanne, Kuciauskas Dalius, Kaupinis Algirdas, Kettunen Mikko I, Liimatainen Timo, Hyvönen Mervi, Valius Mindaugas, Gröhn Olli, Lehto Vesa-Pekka. 2016. Tailored Dual PEGylation of Inorganic Porous Nanocarriers for Extremely Long Blood Circulation in Vivo. ACS Applied Materials & Interfaces 8 48: 32723-32731. 2016

Peters Björn-Hendrik, Staels Lotte, Rantanen Jimi, Molnár Ferdinand, De Beer Thomas, Lehto Vesa-Pekka, Ketolainen Jarkko. 2016. Effects of Cooling Rate in Microscale and Pilot Scale Freeze-Drying - Variations in Excipient Polymorphs and Protein Secondary Structure. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 95: 72-81. 2016

Tamarov Konstantin, Xu Wujun, Osminkina Liubov, Zinovyev Sergey, Soininen Pasi, Kudryavtsev Andrey, Gongalsky Maxim, Gaydarova Azha, Närvänen Ale, Timoshenko Victor, Lehto Vesa-Pekka. 2016. Temperature responsive porous silicon nanoparticles for cancer therapy - spatiotemporal triggering through infrared and radiofrequency electromagnetic heating. JOURNAL OF CONTROLLED RELEASE 241: 220-228. 2016

Riikonen Joakim, Xu Wujun, Lehto Vesa-Pekka. 2015. Porous Silicon in Drug Delivery Applications. Teoksessa: Dusan Losic, Abel Santos (toim.) Electrochemically engineered nanoporous materials : methods, properties and applications. SPRINGER. s. 163-185. 2015

Veselá Petra, Riikonen Joakim, Nissinen Tuomo, Lehto Vesa-Pekka, Slovák Václav. 2015. Optimisation of thermoporometry measurements to evaluate mesoporous organic and carbon xero-, cryo- and aerogels. Thermochimica Acta 621: 81-89. 2015

Special Issue on the recent trends in Thermal Analysis and Calorimetry in the European Region. Lehto Vesa-Pekka, Lastusaari Mika, Kaljuvee Tiit. 2015 2015

Soikkeli M, Sievänen K, Peltonen J, Kaasalainen T, Timonen M, Heinonen P, Rönkkö S, Lehto V -P, Kavakka JS, Heikkinen S. 2015. Synthesis and in vitro phantom NMR and MRI studies of fully organic free radicals, TEEPO-glucose and TEMPO-glucose, potential contrast agents for MRI. RSC Advances 5 20: 15507-15510. 2015

Xu Wujun, Thapa Rinez, Liu Dongfei, Nissinen Tuomo, Granroth Sari, Närvänen Ale, Suvanto Mika, Santos Hélder A, Lehto Vesa-Pekka. 2015. Smart porous silicon nanoparticles with polymeric coatings for sequential combination therapy. Molecular Pharmaceutics 12 11: 4038-4047. 2015

Riikonen Joakim, Rigolet Severinne, Marichal Claire, Aussenac Fabien, Lalevee Jacques, Morlet-Savary Fabrice, Fioux Philippe, Dietlin Celine, Bonne Magali, Lebeau Benedicte, Lehto Vesa-Pekka. 2015. Endogenous Stable Radicals for Characterization of Thermally Carbonized Porous Silicon by Solid-State Dynamic Nuclear Polarization C-13 NMR. JOURNAL OF PHYSICAL CHEMISTRY. C 119 33: 19272-19278. 2015

Lehto Vesa-Pekka, Lastusaari Mika, Kaljuvee Tiit. 2015. Preface in the Special Issue on the recent trends in Thermal Analysis and Calorimetry in the European Region. Journal of Thermal Analysis and Calorimetry 121 1: 1-5. 2015

Kovalainen Miia, Mönkäre Juha, Riikonen Joakim, Pesonen Ullamari, Vlasova Maria, Salonen Jarno, Lehto Vesa-Pekka, Järvinen Kristiina, Herzig Karl-Heinz. 2015. Novel Delivery Systems for Improving the Clinical Use of Peptides. PHARMACOLOGICAL REVIEWS 67 3: 541-561. 2015

Korhonen Eveliina, Rönkkö Seppo, Hillebrand Satu, Riikonen Joakim, Xu Wujun, Järvinen Kristiina, Lehto Vesa-Pekka, Kauppinen Anu. 2015. Cytotoxicity assessment of porous silicon microparticles for ocular drug delivery. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 2016; 100: 1-8. 2015

Jalkanen Tero, Määttänen Anni, Mäkilä Ermei, Tuura Jaani, Kaasalainen Martti, Lehto Vesa-Pekka, Ihalainen Petri, Peltonen Jouko, Salonen Jarno. 2015. Fabrication of Porous Silicon Based Humidity Sensing Elements on Paper. Journal of Sensors 2015: 927396. 2015

Riikonen Joakim, Correia Alexandra, Kovalainen Miia, Näkki Simo, Lehtonen Marko, Leppänen Jukka, Rantanen Jimi, Xu Wujun, Araújo Francisca, Hirvonen Jouni, Järvinen Kristiina, Santos Hélder A, Lehto Vesa-Pekka. 2015. Systematic in vitro and in vivo study on porous silicon to improve the oral bioavailability of celecoxib. BIOMATERIALS 52: 44-55. 2015

Pajula Katja, Wittoek Lieke, Lehto Vesa-Pekka, Ketolainen Jarkko, Korhonen Ossi. 2014. Phase separation in co-amorphous systems: in silico prediction and the experimental challenge of detection. Molecular Pharmaceutics 11: 2271-2279. 2014

Xu Wujun, Rytkönen Jussi, Rönkkö Seppo, Nissinen Tuomo, Kinnunen Tuure, Suvanto Mika, Närvänen Ale, Lehto Vesa-Pekka. 2014. A Nanostopper Approach To Selectively Engineer the Surfaces of Mesoporous Silicon. CHEMISTRY OF MATERIALS 26 23: 6734-6742. 2014

Vlasova Maria A, Rytkönen Jussi, Riikonen Joakim, Tarasova Olga S, Mönkäre Juha, Kovalainen Miia, Närvänen Ale, Salonen Jarno, Herzig Karl-Heinz, Lehto Vesa-Pekka, Järvinen Kristiina. 2014. Nanocarriers and the delivered drug: effect interference due to intravenous administration. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 63: 96-102. 2014

Vlasova Maria A, Tarasova Olga S, Riikonen Joakim, Raula Janne, Lobach Anatoly S, Borzykh Anna A, Smirin Boris V, Kauppinen Esko I, Eletskii Alexander V, Herzig Karl-Heinz, Salonen Jarno, Tavi Pasi, Lehto Vesa-Pekka, Järvinen Kristiina. 2014. Injected nanoparticles: The combination of experimental systems to assess cardiovascular adverse effects. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 87: 64-72. 2014

Näkki Simo, Rytkönen Jussi, Nissinen Tuomo, Florea Cristina, Riikonen Joakim, Ek Paul, Zhang Hongbo, Santos Helder A, Närvänen Ale, Xu Wujun, Lehto Vesa-Pekka. 2014. Improved stability and biocompatibility of nanostructured silicon drug carrier for intravenous administration. ACTA BIOMATERIALIA 2015; 13: 207-215. 2014

Nissinen Tuomo, Näkki Simo, Latikka Mika, Heinonen Markku, Liimatainen Timo, Xu Wujun, Ras Robin HA, Gröhn Olli, Riikonen Joakim, Lehto Vesa-Pekka. 2014. Facile synthesis of biocompatible superparamagnetic mesoporous nanoparticles for imageable drug delivery. Microporous and Mesoporous Materials 195: 2-8. 2014

Modesto-Lopez Luis B, Miettinen Mirella, Riikonen Joakim, Torvela Tiina, Pfüller Carsten, Lehto Vesa-Pekka, Lähde Anna, Jokiniemi Jorma. 2014. Films of Graphene Nanomaterials Formed by Ultrasonic Spraying of Their Stable Suspensions. AEROSOL SCIENCE AND TECHNOLOGY 2015; 49 1: 45-56. 2014

Dongfei Liu, Hongbo Zhang, Bárbara Herranz-Blanco, Ermei Mäkilä, Vesa-Pekka Lehto, Jarno Salonen, Jouni Hirvonen, Hélder A. Santos. 2014. Microfluidic assembly of monodisperse multistage pH-responsive polymer/porous silicon composites for precisely controlled multi-drug delivery. Small 10 10: 2029-2038. 2014

Lehto Vesa-Pekka, Riikonen Joakim. 2014. Drug loading and characterization of porous silicon materials: Santos Hélder A, Porous Silicon for Biomedical Applications. 337-355. 2014

Turunen Elina, Korhonen Ossi, Lehto Vesa-Pekka, Kauppinen Ari, Ahtiainen Hanne, Järvinen Kristiina, Jarho Pekka. 2013. Effect of storage on the dissolution rate of a fast-dissolving perphenazine/β-cyclodextrin complex. JOURNAL OF PHARMACY AND PHARMACOLOGY 2014:66: 367-377. 2013

Rytkönen Jussi, Arukuusk Piret, Xu Wujun, Kurrikoff Kaido, Langel Ulo, Lehto Vesa-Pekka, Närvänen Ale. 2013. Porous silicon-cell penetrating peptide hybrid nanocarrier for intracellular delivery of oligonucleotides. Molecular Pharmaceutics 2014:11: 382-390. 2013

Priemel Petra A, Laitinen Riikka, Barthold Sarah, Grohganz Holger, Lehto Vesa-Pekka, Rades Thomas, Strachan Clare J. 2013. Inhibition of surface crystallisation of amorphous indomethacin particles in physical drug-polymer mixtures. INTERNATIONAL JOURNAL OF PHARMACEUTICS 456: 301-306. 2013

Liu Dongfei, Bimbo Luis M, Mäkilä Ermei, Villanova Francesca, Kaasalainen Martti, Herranz-Blanco Barbara, Caramella Carla M, Lehto Vesa-Pekka, Salonen Jarno, Herzig Karl-Heinz, Hirvonen Jouni, Santos Hélder A.. 2013. Co-delivery of a hydrophobic small molecule and a hydrophilic peptide by porous silicon nanoparticles. JOURNAL OF CONTROLLED RELEASE 170 2: 268-278. 2013

Lehto Vesa-Pekka, Salonen Jarno, Santos Helder, Riikonen Joakim. 2013. Nanostructured Silicon-Based Materials as a Drug Delivery System for Water-Insoluble Drugs: Dennis Douroumis, Alfred Fahr, Drug Delivery Strategies for Poorly Water-Soluble Drugs. -. 2013

Huotari Anne, Xu Wujun, Mönkäre Juha, Kovalainen Miia, Herzig Karl-Heinz, Lehto Vesa-Pekka, Järvinen Kristiina. 2013. Effect of surface chemistry of porous silicon microparticles on glucagon-like peptide-1 (GLP-1) loading, release and biological activity. INTERNATIONAL JOURNAL OF PHARMACEUTICS 454: 67-73. 2013

Hellstén Sanna, Han Bing, Mäkilä Ermei, Niemi Harri, Salonen Jarno, Lehto Vesa-Pekka, Stelzer Torsten, Louhi-Kultanen Marjatta, Ulrich Joachim. 2013. Insights into the Evaporation Kinetics of Indomethacin Solutions. Chemical Engineering and Technology 36 8: 1300-1306. 2013

Xu Wujun, Riikonen Joakim, Nissinen Tuomo, Suvanto Mika, Rilla Kirsi, Li Bojie, Wang Qiang, Deng Feng, Lehto Vesa-Pekka. 2012. Amine Surface Modifications and Fluorescent Labeling of Thermally Stabilized Mesoporous Silicon Nanoparticles. JOURNAL OF PHYSICAL CHEMISTRY. C 116 42: 22307-22314. 2012

XU Wujun, Riikonen Joakim, Lehto Vesa-Pekka. 2012. Mesoporous systems for poorly soluble drugs. INTERNATIONAL JOURNAL OF PHARMACEUTICS 453 1: 181-197. 2012

Vishal Koradia, Mikko Tenho, Heidi Lopez de Diego, Michiel Ringkjøbing-Elema, Jørn Møller-Sonnergaard, Jarno Salonen, Vesa-Pekka Lehto and Jukka Rantanen. 2012. Investigation of Solid Phase Composition on Tablet Surfaces by Grazing Incidence X-ray Diffraction. PHARMACEUTICAL RESEARCH 29: 134-144. 2012

Riikonen Joakim, Salomäki Mikko, van Wonderen Jessica , Kemell Marianna, Xu, Wujun, Korhonen Ossi, Ritala Mikko, MacMillan Fraser, Salonen Jarno, Lehto Vesa-Pekka. 2012. Surface Chemistry, Reactivity, and Pore Structure of Porous Silicon Oxidized by Various Methods. LANGMUIR 28 28: 10573−10583. 2012

Rytkönen Jussi, Miettinen Riitta, Kaasalainen Martti, Lehto Vesa-Pekka, Salonen Jarno, Närvänen Ale. 2012. Functionalization of mesoporous silicon nanoparticles for targeting and bioimaging purposes. Journal of Nanomaterials 2012: Article ID: 896562. 2012

Tero Jalkanen, Ermei Mäkilä, Anni Määttänen, Jaani Tuura, Martti Kaasalainen, Vesa-Pekka Lehto, Petri Ihalainen, Jouko Peltonen and Jarno Salonen. 2012. Porous silicon micro- and nanoparticles for printed humidity sensors. Applied Physics Letters 101 26: 263110-263113. 2012

Pajula Katja, Lehto Vesa-Pekka, Ketolainen Jarkko, Korhonen Ossi. 2012. Computational approach for fast screening of small molecular candidates to inhibit crystallization in amorphous drugs Molecular Pharmaceutics 9: 2844-2855. 2012

Kovalainen Miia, Mönkäre Juha, Mäkilä Ermei, Salonen Jarno, Lehto Vesa-Pekka, Herzig Karl-Heinz, Järvinen Kristiina. 2012. Mesoporous silicon (PSi) for sustained peptide delivery: effect of PSi microparticle surface chemistry on peptide YY3-36 release PHARMACEUTICAL RESEARCH 29: 837-846. 2012

Kovalainen Miia, Mönkäre Juha, Kaasalainen Martti, Riikonen Joakim, Lehto Vesa-Pekka, Salonen Jarno, Herzig Karl-Heinz, Järvinen Kristiina. 2012. Development of porous silicon nanocarriers for parenteral peptide delivery. Molecular Pharmaceutics 2013:10: 353-359. 2012

Kaasalainen Martti, Mäkilä Ermei, Riikonen Joakim, Kovalainen Miia, Järvinen Kristiina, Herzig Karl-Heinz, Lehto Vesa-Pekka, Salonen Jarno. 2012. Effect of isotonic solutions and peptide adsorption on zeta potential of porous silicon nanoparticle drug delivery formulations. INTERNATIONAL JOURNAL OF PHARMACEUTICS 431 1-2: 230-236. 2012

Järvinen Kristiina, Jokiniemi Jorma, Lammi Mikko, Lappalainen Reijo, Närvänen Ale, Pakkanen Tapani A, Lehto Vesa-Pekka. 2012. Nanoteknologia biomateriaalien ja lääkkeiden kantaja-aineiden pintojen räätälöinnissä. DUODECIM 128: 2085-2092. 2012

Nieminen, P., Paakkonen, T., Eerilä, J., Riikonen, J., Lehto, V.-P., Mustonen, A.-M.. 2012. Freezing Tolerance and Low Molecular Weight Cryoprotectants in an Invasive Parasitic Fly, the Deer Ked (Lipoptena cervi) JOURNAL OF EXPERIMENTAL ZOOLOGY. PART A. COMPARATIVE EXPERIMENTAL BIOLOGY 317: 1-8. 2012

Riikonen J, Salonen J, Lehto V-P. 2011. Utilising thermoporometry to obtain new insights into nanostructured materials - Part 1 Journal of Thermal Analysis and Calorimetry 105: 811-821. 2011

Turunen Elina, Mannila Janne, Laitinen Riikka, Riikonen Joakim, Lehto Vesa-Pekka, Järvinen Tomi, Ketolainen Jarkko, Järvinen Kristiina, Jarho Pekka. 2011. Fast-dissolving sublingual solid dispersion and cyclodextrin complex increase the absorption of perphenazine in rabbits. JOURNAL OF PHARMACY AND PHARMACOLOGY 63: 19 - 25. 2011

Torvela Tiina, Lähde Anna, Mönkäre Juha, Riikonen Joakim, Lehtinen Kari E.J., Järvinen Kristiina, Lehto Vesa-Pekka, Jokiniemi Jorma, Joutsensaari Jorma. 2011. Low-temperature aerosol flow reactor method for preparation of surface stabilized pharmaceutical nanocarriers. JOURNAL OF AEROSOL SCIENCE 42 10: 645-656. 2011

Sarparanta M, Mäkilä E, Heikkilä T, Salonen J, Kukk E, Lehto V-P, Santos H, Hirvonen J, Airaksinen A. 2011. (18)F-labeled modified porous silicon particles for investigation of drug delivery carrier distribution in vivo with positron emission tomography Molecular Pharmaceutics 8: 1799-1806. 2011

Santos H, Bimbo L, Lehto V-P, Airaksinen A, Salonen J, Hirvonen J. 2011. Multifunctional porous silicon for therapeutic drug delivery and imaging CURRENT DRUG DISCOVERY TECHNOLOGIES 8: 228-249. 2011

Riikonen J, Salonen J, Lehto V-P. 2011. Utilising thermoporometry to obtain new insights into nanostructured materials - Part 2 Journal of Thermal Analysis and Calorimetry 105: 823-830. 2011

Santos H, Salonen J, Bimbo L, Lehto V-P, Peltonen L, Hirvonen J. 2011. Mesoporous materials as controlled drug delivery formulations JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY 21: 139-155. 2011

Mönkäre Juha, Riikonen Joakim, Rauma Elina, Salonen Jarno, Lehto Vesa-Pekka, Järvinen Kristiina. 2011. In vitro dissolution methods for hydrophilic and hydrophobic porous silicon microparticles. Pharmaceutics 3 2: 315-325. 2011

Limnell T, Heikkilä T, Santos H, Sistonen S, Hellstén S, Laaksonen T, Peltonen L, Kumar N, Murzin D, Louhi-Kultanen M, Salonen J, Hirvonen J, Lehto V-P. 2011. Physicochemical stability of high indomethacin payload ordered mesoporous silica MCM-41 and SBA-15 microparticles INTERNATIONAL JOURNAL OF PHARMACEUTICS 416: 242-251. 2011

Kovalainen M, Mönkäre J, Mäkilä E, Salonen J, Lehto V-P, Herzig K-H, Järvinen K. 2011. Enhanced bioavailability of peptide YY using nanoporous silicon as a drug carrier: NSTI, Technical Proceedings of the 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011, 3. 322-325. 2011

Koivisto Antti, Mäkinen Maija, Rossi Elina, Lindberg Hanna, Miettinen Mirella, Falck Ghita, Norppa Hannu, Alenius Harri, Korpi Anne, Riikonen Joakim, Vanhala Esa, Vippola Minnamari, Pasanen Pertti, Lehto Vesa-Pekka, Savolainen Kai, Jokiniemi Jorma, Hämeri Kaarle. 2011. Aerosol characterization and lung deposition of synthesized TiO2 nanoparticles for murine inhalation studies. JOURNAL OF NANOPARTICLE RESEARCH 13: 2949-2961. 2011

Kilpeläinen Miia, Mönkäre Juha, Vlasova Maria, Riikonen Joakim, Lehto Vesa-Pekka, Salonen Jarno, Järvinen Kristiina, Herzig Karl-Heinz. 2011. Nanostructured porous silicon microparticles enable sustained peptide (Melanotan II) delivery EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 77: 20-25. 2011

Bimbo L, Mäkilä E, Laaksonen T, Lehto V-P, Salonen J, Hirvonen J, Santos H. 2011. Drug permeation across intestinal epithelial cells using porous silicon nanoparticles BIOMATERIALS 32: 2625-2633. 2011

Miettinen M, Johansson M, Suvanto S, Riikonen J, Tapper U, Pakkanen TT, Lehto V-P, Jokiniemi J, Lähde A. 2011. Atmospheric pressure chemical vapour synthesis of silicon-carbon nanoceramics from hexamethyldisilane in high temperature aerosol reactor JOURNAL OF NANOPARTICLE RESEARCH 13 10: 4631-4645. 2011

Pajula K, Taskinen M, Lehto V-P, Ketolainen J & Korhonen O. 2010. Predicting the formation and stability of amorphous small molecule binary mixtures from computationally determined Flory-Huggins interaction parameter and phase diagram. Molecular Pharmaceutics 7 3: 795-804. 2010

Santos HA, Riikonen J, Salonen J, Mäkilä E, Heikkilä T, Laaksonen T, Peltonen L, Lehto V-P, Hirvonen J. 2010. In vitro cytotoxicity of porous silicon microparticles: Effect of the particle concentration, surface chemistry and size ACTA BIOMATERIALIA 6: 2721-2731. 2010

Raula J, Thielmann F, Naderi M, Lehto V-P, Kauppinen EI. 2010. Investigations on particle surface characteristics vs. dispersion behaviour of L-leucine coated carrier-free inhalable powders. INTERNATIONAL JOURNAL OF PHARMACEUTICS 385: 79-85. 2010

Laitinen R, Suihko E, Bjorkqvist M, Riikonen J, Lehto V-P, Jarvinen K & Ketolainen J. 2010. Perphenazine solid dispersions for orally fast-disintegrating tablets: physical stability and formulation DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY 36 5: 601 - 613. 2010

Lehto V-P, Tenho M, Hämäläinen O-P, Salonen J. 2010. Calorimetric determination of dissolution enthalpy with a novel flow-through method. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 53: 821-825. 2010

Heikkilä T, Santos HA, Kumar N, Murzin DY, Salonen J, Laaksonen T, Peltonen L, Hirvonen J, Lehto V-P. 2010. Cytotoxicity study of ordered mesoporous silica MCM-41 and SBA-15 microparticles on Caco-2 cells EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS 74: 483-494. 2010

Bimbo LM, Sarparanta M, Santos HA, Airaksinen AJ, Mäkilä E, Laaksonen T, Peltonen L, Lehto V-P, Hirvonen J, Salonen J. 2010. Biocompatibility of thermally hydrocarbonized porous silicon nanoparticles and their biodistribution in rats. ACS NANO 4 6: 3023-3032. 2010

Jalkanen T, Torres-Costa V, Salonen J, Björkqvist M, Mäkilä E, Martinez-Duart JM, Lehto V-P. 2009. Optical gas sensing properties of thermally hydrocarbonized porous silicon Bragg reflectors OPTICS EXPRESS: THE INTERNATIONAL ELECTRONIC JOURNAL OF OPTICS 17 7: 5446-5456. 2009

Kilpeläinen M, Riikonen J, Vlasova MA, Huotari A, Lehto VP, Salonen J, Herzig KH, Järvinen K. 2009. In vivo delivery of a peptide, ghrelin antagonist, with mesoporous silicon microparticles JOURNAL OF CONTROLLED RELEASE 137: 166-170. 2009

Miettinen M, Riikonen J, Tapper U, Backman U, Joutsensaari J, Auvinen A, Lehto VP, Jokiniemi J. 2009. Development of a highly controlled gasphase nanoparticle generator for inhalation exposure studies. HUMAN AND EXPERIMENTAL TOXICOLOGY 28: 413-419. 2009

Riikonen J, Mäkilä E, Salonen J, Lehto V-P. 2009. Determination of the physical state of drug molecules in mesoporous silicon with different surface chemistries. LANGMUIR 25 11: 6137-6142. 2009

Riikonen J, Salonen J, Kemell M, Kumar N, Murzin DY, Ritala M, Lehto V-P. 2009. A novel method of quantifying the u-shaped pores in SBA-15. JOURNAL OF PHYSICAL CHEMISTRY. C 113: 20349-20354. 2009

Yhteystiedot

Organisaatio

Sähköposti

Puhelin

Tutkimusryhmät - UEF

PROJEKTIT - UEF

Julkaisut