Maria Pikkarainen

Obesity and Brain Vulnerability in Normal and Abnormal Aging: A Multimodal MRI Study

Dake, Manmohi D; De Marco, Matteo; Blackburn, Daniel J; Wilkinson, Iain D; Remes, Anne; Liu, Yawu; Pikkarainen, Maria; Hallikainen, Merja; Soininen, Hilkka; Venneri, Annalena. 2021. Journal of Alzheimer's disease reports

Metabolic Profiles Help Discriminate Mild Cognitive Impairment from Dementia Stage in Alzheimer's Disease.

Jääskeläinen, O; Hall, A; Tiainen, M; van Gils, M; Lötjönen, J; Kangas, AJ; Helisalmi, S; Pikkarainen, M; Hallikainen, M; Koivisto, A; Hartikainen, P; Hiltunen, M; Ala-Korpela, M; Soininen, P; Soininen, H; Herukka, S-K. 2020. Journal of Alzheimer's disease

White Matter Hyperintensities are No Major Confounder for Alzheimer's Disease Cerebrospinal Fluid Biomarkers

van Waalwijk van Doorn, Linda J C; Ghafoorian, Mohsen; van Leijsen, Esther M C; Claassen, Jurgen A H R; Arighi, Andrea; Bozzali, Marco; Cannas, Jorge; Cavedo, Enrica; Eusebi, Paolo; Farotti, Lucia; Fenoglio, Chiara; Fortea, Juan; Frisoni, Giovanni B; Galimberti, Daniela; Greco, Viviana; Herukka, Sanna-Kaisa; Liu, Yawu; Lleó, Alberto; de Mendonça, Alexandre; Nobili, Flavio M; et al. [incl. Pikkarainen, Maria; Soininen, Hilkka]. 2020. Journal of Alzheimer's disease

cCOG: A web-based cognitive test tool for detecting neurodegenerative disorders

Rhodius-Meester, HFM; Paajanen, T; Koikkalainen, J; Mahdiani, S; Bruun, M; Baroni, M; Lemstra, AW; Scheltens, P; Herukka, SK; Pikkarainen, M; Hall, A; Hänninen, T; Ngandu, T; Kivipelto, M; van Gils, M; Hasselbalch, SG; Mecocci, P; Remes, A; Soininen, H; van der Flier, WM; Lötjönen, J. 2020. Alzheimer's & dementia : diagnosis, assessment & disease monitoring

Low Serum High-Density Lipoprotein Cholesterol Levels Associate with the C9orf72 Repeat Expansion in Frontotemporal Lobar Degeneration Patients

Jääskeläinen, O; Solje, E; Hall, A; Katisko, K; Korhonen, V; Tiainen, M; Kangas, AJ; Helisalmi, S; Pikkarainen, M; Koivisto, A; Hartikainen, P; Hiltunen, M; Ala-Korpela, M; Soininen, H; Soininen, P; Haapasalo, A; Remes, AM; Herukka, SK. 2019. Journal of Alzheimer's disease

Association Between Later Life Lifestyle Factors and Alzheimer's Disease Biomarkers in Non-Demented Individuals: A Longitudinal Descriptive Cohort Study

Reijs BLR, Vos SJB, Soininen H, Lötjonen J, Koikkalainen J, Pikkarainen M, Hall A, Vanninen R, Liu Y, Herukka SK, Freund-Levi Y, Frisoni GB, Frölich L, Nobili F, Rikkert MO, Spiru L, Tsolaki M, Wallin ÅK, Scheltens P1, Verhey F, Visser PJ. 2017. Journal of Alzheimer's disease

Hippocampal Sclerosis and Epilepsy in Elderly Population

Rauramaa Tuomas, Solomon Alina, Pikkarainen Maria, Kälviäinen Reetta, Alafuzoff Irina. 2017. Journal of Alzheimer's disease & Parkinsonism

Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes

van Waalwijk van Doorn LC, Gispert JD, Kuiperij HB, Claassen, JAHR, Arighi A, Baldeiras I, Blennow K, Bozzali M, Castelo-Branco M, Cavedo E, Emek-Savas D, Eren E, Eusebi P, Farotti L, Fenoglio C, Ormaechea JF, Freund-Levi Y, Frisoni G, Galimberti D, Genc S et al. 2017. Journal of Alzheimer's disease

The Modified Frontal Behavioral Inventory (FBI-mod) for Patients with Frontotemporal Lobar Degeneration, Alzheimer's Disease, and Mild Cognitive Impairment

Suhonen NM, Hallikainen I, Hänninen T, Jokelainen J, Krüger J, Hall A, Pikkarainen M, Soininen H, Remes AM. 2017. Journal of Alzheimer's disease

The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer's pathology

Westwood S, Liu B, Baird AL, Anand S, Nevado-Holgado AJ, Newby D, Pikkarainen M, Hallikainen M, Kuusisto J, Streffer JR, Novak G, Blennow K, Andreasson U, Zetterberg H, Smith U, Laakso M, Soininen H, Lovestone S. 2017. Alzheimer's research and therapy

Biological confounders for the values of cerebrospinal fluid proteins in Parkinson's disease and related disorders

Mollenhauer Brit, Parnetti Lucilla, Rektorova Irena, Kramberger Milica G, Pikkarainen Maria, Schulz-Schaeffer Walter J, Aarsland Dag, Svenningsson Per, Farotti Lucia, Verbeek Marcel M, Schlossmacher Michael G. 2016. Journal of neurochemistry

Alzheimer's disease: a report from the 7th Kuopio Alzheimer symposium

Haapasalo Annakaisa, Pikkarainen Maria, Soininen Hilkka. 2015. Neurodegenerative disease management

Chasing the effects of pre-analytical confounders - a multicenter study on CSF-AD biomarkers

Leitão Maria João, Baldeiras Inês, Herukka Sanna-Kaisa, Pikkarainen Maria, Leinonen Ville, Simonsen Anja Hviid, Perret-Liaudet Armand, Fourier Anthony, Quadrio Isabelle, Veiga Pedro Mota, de Oliveira Catarina Resende. 2015. Frontiers in neurology

Erratum to: Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium (vol 122, pg 957, 2015)

Alafuzoff Irina, Pikkarainen Maria, Neumann Manuela, Arzberger Thomas, Al-Sarraj Safa, Bodi Istvan, Bogdanovic Nenad, Bugiani Orso, Ferrer Isidro, Gelpi Ellen, Gentleman Stephen, Giaccone Giorgio, Graeber Manuel B., Hortobagyi Tibor, Ince Paul G., Ironside James W., Kavantzas Nikolaos, King Andrew, Korkolopoulou Penelope, Kovacs Gabor G. et al.. 2015. Journal of neural transmission

Synucleinopathies

Alafuzoff Irina, Pikkarainen Maria, Parkkinen Laura. 2015. Cambridge University Press

Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium

Alafuzoff I, Pikkarainen M, Neumann M, Arzberger T, Al-Sarraj S, Bodi I, Bogdanovic N, Bugiani O, Ferrer I, Gelpi E, Gentleman S, Giaccone G, Graeber MB, Hortobagyi T, Ince PG, Ironside JW, Kavantzas N, King A, Korkolopoulou P, Kovács GG, et al.. 2014. Journal of neural transmission

Consensus recommendations on pathologic changes in the hippocampus: A postmortem multicenter inter-rater study

Rauramaa T, Pikkarainen M, Englund E, Ince PG, Jellinger K, Paetau A, Alafuzoff I. 2013. Journal of neuropathology and experimental neurology

GRN variant rs5848 reduces plasma and brain levels of granulin in Alzheimer's disease patients

Kämäläinen A, Viswanathan J, Natunen T, Helisalmi S, Kauppinen T, Pikkarainen M, Pursiheimo J-P, Alafuzoff I, Kivipelto M, Haapasalo A, Soininen H, Herukka S-K, Hiltunen M. 2013. Journal of Alzheimer's disease

An antibody with high reactivity for disease-associated alfa-synuclein reveals extensive brain pathology

Kovacs G, Wagner U, Dumont B, Pikkarainen M, Osman AA, Streichenberger N, Leisser I, Verchere J, Baron T, Alafuzoff I, Budka H, Perret-Liaudet A, Lachmann I. 2012. Acta neuropathologica

Unusual clinical presentation and neuropathology in two subjects with fused-in sarcoma (FUS) positive inclusions

Hartikainen PH, Pikkarainen M, Hänninen T, Soininen H, Alafuzoff I. 2012. Neuropathology

Cardiovascular diseases and hippocampal infarcts

Rauramaa T, Pikkarainen M, Englund E, Ince PG, Jellinger K, Paetau A, Parkkinen L, Alafuzoff I. 2011. Hippocampus

Distribution and pattern of pathology in subjects with familial or sporadic late-onset cerebellar Ataxia as assessed by p62/Sequestosome immunohistochemistry

Pikkarainen M, Hartikainen P, Soininen H, Alafuzoff I. 2011. Cerebellum

TAR-DNA binding protein-43 and anterations in the hippocampus

Rauramaa T, Pikkarainen M, Englund E, Ince PG, Jellinger K, Paetau A, Alafuzoff I. 2011. Journal of neural transmission

Brain pathology in three subjects from the same pedigree with presenilin-1 (PSEN1) P264L mutation

Martikainen P, Pikkarainen M, Pöntynen K, Hiltunen M, Lehtovirta M, Tuisku S, Soininen H & Alafuzoff I. 2010. Neuropathology and applied neurobiology

Assessment of beta-amyloid deposits in human brain: a study of the BrainNet Europe Consortium

Alafuzoff I, Thal DR, Arzberger T, Bogdanovic N, Ala-sarraj S, Bodi I, Boluda S, Bugiani O, Duyckaerts C, Gelpi E..., Pikkarainen M, Revesz T.... 2009. Acta neuropathologica

Expression of collagen XVII and ubiquitin-binding protein p62 in motor neuron disease

Seppänen A, Pikkarainen M, Hartikainen P, Hofmann SC, Majamaa K, Alafuzoff I. 2009. Brain research

Hyperphosphorylated Tau in the occipital cortex in aged nondemented subjects

Pikkarainen M, Kauppinen T, Alafuzoff I. 2009. Journal of neuropathology and experimental neurology

Neuropathologic features of frontotemporal lobar degeneration with ubiquitin-positive inclusions visualized with ubiquitin-binding protein p62 immunohistochemistry

Pikkarainen M, Hartikainen P, Alafuzoff I. 2008. Journal of neuropathology and experimental neurology

Interlaboratory comparison of assessments of Alzheimer disease-related lesions: a study of the BrainNet Europe consortium

Alafuzoff I, Pikkarainen M, Al-Sarraj S, Arzberger T, Bell J, Bodi I, Bogdanovic N, Budka H, Bugiani O, Ferrer I, Gelpi E, Giaccone G, ... et al.. 2006. Journal of neuropathology and experimental neurology

Projections from the amygdaloid complex to the claustrum and the endopiriform nucleus: a Phaseolus vulgaris leucoagglutinin study in the rat

Majak K, Pikkarainen M, Kemppainen S, Jolkkonen E, Pitkänen A. 2002. Journal of comparative neurology

Projections from the amygdaloid complex to the magnocellular cholinergic basal forebrain in rat

Jolkkonen E, Miettinen R, Pikkarainen M, Pitkänen A. 2002. Neuroscience

Interconnectivity between the amygdaloid complex and the amygdalostriatal transition area: a PHA-L study in rat

Jolkkonen E, Pikkarainen M, Kemppainen S, Pitkänen A. 2001. Journal of comparative neurology

Projections from the lateral, basal and accessory basal nuclei of the amygdala to the perirhinal and postrhinal cortices in rat

Pikkarainen M, Pitkanen A. 2001. Cerebral cortex

The Rat Parahippocampal Region. Chemoarchitectonics and Afferent Connections from the Amygdala with Special Emphasis on the Entorhinal Cortex

Pikkarainen M. 2001. Kuopion yliopiston julkaisuja C. Luonnontieteet ja ympäristötieteet

Reciprocal connections between the amygdala and the hippocampal formation, perirhinal cortex, and postrhinal cortex in rat: a review

Pitkänen A, Pikkarainen M, Nurminen N, Ylinen A. 2000. Annals of the New York Academy of Sciences

Projections from the lateral, basal, and accessory basal nuclei of the amygdala to the hippocampal formation in rat

Pikkarainen M, Rönkkö S, Savander V, Insausti R, Pitkänen A. 1999. Journal of comparative neurology

Distribution of calretinin-immunoreactivity in the rat entorhinal cortex:coexistence with GABA

Miettinen M, Pitkänen A, Miettinen R. 1997. Journal of comparative neurology

Coexistence of parvalbumin and GABA in nonpyramidal neurons of the rat entorhinal cortex

Miettinen M, Koivisto E, Riekkinen P Sr, Miettinen R. 1996. Brain research

Tarkenna hakuasi

Tutkimusryhmät

Projektit

Obesity and Brain Vulnerability in Normal and Abnormal Aging: A Multimodal MRI Study

Metabolic Profiles Help Discriminate Mild Cognitive Impairment from Dementia Stage in Alzheimer's Disease.

White Matter Hyperintensities are No Major Confounder for Alzheimer's Disease Cerebrospinal Fluid Biomarkers

cCOG: A web-based cognitive test tool for detecting neurodegenerative disorders

Low Serum High-Density Lipoprotein Cholesterol Levels Associate with the C9orf72 Repeat Expansion in Frontotemporal Lobar Degeneration Patients

Association Between Later Life Lifestyle Factors and Alzheimer's Disease Biomarkers in Non-Demented Individuals: A Longitudinal Descriptive Cohort Study

Hippocampal Sclerosis and Epilepsy in Elderly Population

Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes

The Modified Frontal Behavioral Inventory (FBI-mod) for Patients with Frontotemporal Lobar Degeneration, Alzheimer's Disease, and Mild Cognitive Impairment

The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer's pathology

Biological confounders for the values of cerebrospinal fluid proteins in Parkinson's disease and related disorders

Alzheimer's disease: a report from the 7th Kuopio Alzheimer symposium

Chasing the effects of pre-analytical confounders - a multicenter study on CSF-AD biomarkers

Erratum to: Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium (vol 122, pg 957, 2015)

Synucleinopathies

Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium

Consensus recommendations on pathologic changes in the hippocampus: A postmortem multicenter inter-rater study

GRN variant rs5848 reduces plasma and brain levels of granulin in Alzheimer's disease patients

An antibody with high reactivity for disease-associated alfa-synuclein reveals extensive brain pathology

Unusual clinical presentation and neuropathology in two subjects with fused-in sarcoma (FUS) positive inclusions

Cardiovascular diseases and hippocampal infarcts

Distribution and pattern of pathology in subjects with familial or sporadic late-onset cerebellar Ataxia as assessed by p62/Sequestosome immunohistochemistry

TAR-DNA binding protein-43 and anterations in the hippocampus

Brain pathology in three subjects from the same pedigree with presenilin-1 (PSEN1) P264L mutation

Assessment of beta-amyloid deposits in human brain: a study of the BrainNet Europe Consortium

Expression of collagen XVII and ubiquitin-binding protein p62 in motor neuron disease

Hyperphosphorylated Tau in the occipital cortex in aged nondemented subjects

Neuropathologic features of frontotemporal lobar degeneration with ubiquitin-positive inclusions visualized with ubiquitin-binding protein p62 immunohistochemistry

Interlaboratory comparison of assessments of Alzheimer disease-related lesions: a study of the BrainNet Europe consortium

Projections from the amygdaloid complex to the claustrum and the endopiriform nucleus: a Phaseolus vulgaris leucoagglutinin study in the rat

Projections from the amygdaloid complex to the magnocellular cholinergic basal forebrain in rat

Interconnectivity between the amygdaloid complex and the amygdalostriatal transition area: a PHA-L study in rat

Projections from the lateral, basal and accessory basal nuclei of the amygdala to the perirhinal and postrhinal cortices in rat

The Rat Parahippocampal Region. Chemoarchitectonics and Afferent Connections from the Amygdala with Special Emphasis on the Entorhinal Cortex

Reciprocal connections between the amygdala and the hippocampal formation, perirhinal cortex, and postrhinal cortex in rat: a review

Projections from the lateral, basal, and accessory basal nuclei of the amygdala to the hippocampal formation in rat

Distribution of calretinin-immunoreactivity in the rat entorhinal cortex:coexistence with GABA

Coexistence of parvalbumin and GABA in nonpyramidal neurons of the rat entorhinal cortex