Tatu Lajunen

DNA Origami Uptake in Y-79 Retinoblastoma Cells Driven by Oligolysine Coating

Klose, Anna; Gounani, Zahra; Raik, Sergei; Koivuniemi, Artturi; Korhonen, Sonja; Reinisalo, Mika; Lajunen, Tatu; Linko, Veikko; Laaksonen, Timo, 2026, Small structures, 7, 10, e70628. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Effective process for screening melanin binding affinity of small molecule drugs and new drug candidates

Vanhanen, Pekka; Reinisalo, Mika; Lajunen, Tatu; Kalinin, Stanislav; Leskinen, Jari; Urtti, Arto, 2026, International journal of pharmaceutics, 698, 126964. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Hyaluronic Acid Decoration Facilitates CD44‐Mediated Targeting and Alters Protein Corona Formation of Extracellular Vesicles

Kyykallio, Heikki; Scurti, Elena; Hanzlíková, Martina; Härkönen, Kirsti; Salo, Tuovi; Keinonen, Veera; Capra, Janne; Viitala, Tapani; Teppo, Jaakko; Lajunen, Tatu; Rilla, Kirsi, 2026, Journal of extracellular vesicles, 15, 4, e70263. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Light-responsive liposomes for on-demand degradation of cellulose-based hydrogels

Gangurde, Puja; Cheng, Yu; Arola, Suvi; Marjamaa, Kaisa; Chan, Feng-Yueh; Efimov, Alexander; Lauren, Patrick; Lajunen, Tatu; Uchihashi, Takayuki; Gounani, Zahra; Laaksonen, Timo, 2026, Carbohydrate polymers, 392, 125855. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Photothermal and photo-oxidation mediated release of lipophilic paclitaxel from liposomes: from formulation to in vitro efficacy and molecular dynamics simulations

Ilvesroiha, Eija; Heinonen, Suvi; Rimmisto, Riikka; Oksanen, Timo; Durandin, Nikita; Bunker, Alex; Koivuniemi, Artturi; Lajunen, Tatu; Laaksonen, Timo, 2026, International journal of pharmaceutics, 702, 127191. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Sustained intravitreal dissolution and kinase inhibition by an inhibitory cGMP analogue after its injection as a suspension of a poorly soluble salt

Valkama, Eetu; Toropainen, Elisa; Singh, Simar Pal; Valtari, Annika; Koskela, Ali; Merivaara, Arto; Perez, Oswaldo; Ruponen, Marika; Groten, John; Schipper, Nicolaas; Urtti, Arto; Vellonen, Kati-Sisko; Lajunen, Tatu; Puranen, Jooseppi, 2026, Biomedicine and pharmacotherapy, 199, 119387. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Drug release and pharmacokinetics of intravitreal liposomal injections: a case study with cyclic guanosine monophosphate derivative

Valkama, Eetu; Sadeghi, Amir; Toropainen, Elisa; Perez, Oswaldo; Schipper, Nicolaas; Ruponen, Marika; Urtti, Arto; Lajunen, Tatu, 2025, European journal of pharmaceutical sciences, 214, 107291. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Fluorescence Anisotropy for Detailed Analysis of Doxorubicin Loading into DNA Origami Nanocarriers for Drug Delivery

Lisitsyna, Ekaterina S; Klose, Anna; Vuorimaa-Laukkanen, Elina; Ijäs, Heini; Lajunen, Tatu; Suhling, Klaus; Linko, Veikko; Laaksonen, Timo, 2025, ACS applied nano materials, 8, 26, 13274-13284. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Harnessing liposomal nanocellulose hydrogel for NIR-light driven on-demand drug delivery

Gangurde, Puja; Gounani, Zahra; Zini, Jacopo; Polez, Roberta Teixeira; Osterberg, Monika; Lauren, Patrick; Lajunen, Tatu; Laaksonen, Timo, 2025, Carbohydrate polymer technologies and applications, 10, 100787. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

In vitro biophysical and biological profiling of commercial lipid-based dry eye products

Jäntti, Janika; Viitaja, Tuomo; Sevón, Julia; Moilanen, Jukka; Lajunen, Tatu; Pajula, Katja; Ekholm, Filip. S.; Ruponen, Marika, 2025, European journal of pharmaceutical sciences, 209, 107104. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

New insights on liposomal formulations based upon tear film lipids: A combined study of safety and ocular surface pharmacokinetics

Jäntti, Janika; Puranen, Jooseppi; Merivaara, Arto; Balla, Anusha; Tuomikoski, Eveliina; Paterno, Jussi; Toropainen, Elisa; Raitanen, Jan-Erik; Lajunen, Tatu; Ekholm, Filip. S; Ruponen, Marika, 2025, European journal of pharmaceutical sciences, 215, 107282. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Protective Role and Enhanced Intracellular Uptake of Curcumin in Retinal Cells Using Self-Emulsifying Drug Delivery Systems (SNEDDS)

Zingale, Elide; Masuzzo, Sebastiano; Lajunen, Tatu; Reinisalo, Mika; Rautio, Jarkko; Consoli, Valeria; D’Amico, Agata Grazia; Vanella, Luca; Pignatello, Rosario, 2025, Pharmaceuticals, 18, 2, 265. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Barcode lipids for absolute quantitation of liposomes in ocular tissues

Merivaara, Arto; Puranen, Jooseppi; Sadeghi, Amir; Zashikhina, Natalia; Pirskanen, Lea; Lajunen, Tatu; Terasaki, Tetsuya; Auriola, Seppo; Vellonen, Kati Sisko; Urtti, Arto, 2024, Journal of controlled release, 370, 1-13. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Development of Focused Ultrasound-Assisted Nanoplexes for RNA Delivery

Ranjan, Sanjeev; Bosch, Stef; Lukkari, Hannamari; Schirmer, Johanna; Aaltonen, Niina; Nieminen, Heikki J; Lehto, Vesa-Pekka; Urtti, Arto; Lajunen, Tatu; Rilla, Kirsi, 2024, Nanomaterials, 14, 13, 1089. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Doxorubicin-loaded DNA origami nanostructures: stability in vitreous and their uptake and toxicity in ocular cells

Klose, Anna; Gounani, Zahra; Ijäs, Heini; Lajunen, Tatu; Linko, Veikko; Laaksonen, Timo, 2024, Nanoscale, 16, 37, 17585-17598. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

PL3 CendR peptide shows specific uptake in cultured Y79 retinoblastoma cells with nucleolar accumulation

Korhonen, Sonja; Bosch, Stef; Erkinheimo, Antero; Lajunen, Tatu; Rilla, Kirsi; Teesalu, Tambet; Subrizi, Astrid; Ruponen, Marika; Urtti, Arto; Reinisalo, Mika, 2024, European journal of pharmaceutical sciences, 201, 106866. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Potential of Extracellular Vesicles as Therapeutics in Retinal Diseases

Bosch, Stef; Lajunen, Tatu; Merivaara, Arto; Rilla, Kirsi; Urtti, Arto, 2024, Rilla, Kirsi, Extracellular Vesicles as Matrix Messengers, 199-226. B2 Kirjan tai muun kokoomateoksen osa

Development of Robust Cationic Light-Activated Thermosensitive Liposomes: Choosing the Right Lipids

Gangurde, Puja; Mahmoudzadeh, Mohammad; Gounani, Zahra; Koivuniemi, Artturi; Laurén, Patrick; Lajunen, Tatu; Laaksonen, Timo, 2023, Molecular pharmaceutics, 20, 11, 5728-5738. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Early-Stage Development of an Anti-Evaporative Liposomal Formulation for the Potential Treatment of Dry Eyes

Jantti, Janika; Viitaja, Tuomo; Sevon, Julia; Lajunen, Tatu; Raitanen, Jan-Erik; Schlegel, Cordula; Viljanen, Mira; Paananen, Riku O; Moilanen, Jukka; Ruponen, Marika; Ekholm, Filip. S, 2023, ACS pharmacology & translational science, 6, 10, 1518-1530. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Establishing a simple perfusion cell culture system for light-activated liposomes

Mäki-Mikola, Eija; Lauren, Patrick; Uema, Natsumi; Kikuchi, Kanako; Takashima, Yuuki; Laaksonen, Timo; Lajunen, Tatu, 2023, Scientific reports, 13, 1, 2050. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Selective drug delivery to the retinal cells: Biological barriers and avenues

Ramsay, Eva; Lajunen, Tatu; Bhattacharya, Madhushree; Reinisalo, Mika; Rilla, Kirsi; Kidron, Heidi; Terasaki, Tetsuya; Urtti, Arto, 2023, Journal of controlled release, 361, 1-19. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Imaging, quantitation and kinetic modelling of intravitreal nanomaterials

Sadeghi, Amir; Ruponen, Marika; Puranen, Jooseppi; Cao, Shoupeng; Ridolfo, Roxane; Tavakoli, Shirin; Toropainen, Elisa; Lajunen, Tatu; Ranta, Veli-Pekka; van Hest, Jan; Urtti, Arto, 2022, International journal of pharmaceutics, 621, 121800. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Liposomal sunitinib for ocular drug delivery: A potential treatment for choroidal neovascularization

Tavakoli, Shirin; Puranen, Jooseppi; Bahrpeyma, Sina; Lautala, Veera E.; Karumo, Suvi; Lajunen, Tatu; del Amo, Eva M.; Ruponen, Marika; Urtti, Arto, 2022, International journal of pharmaceutics, 620, 121725. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Nanoparticle release from anionic nanocellulose hydrogel matrix

Auvinen, Vili-Veli; Laurén, Patrick; Shen, Boxuan; Isokuortti, Jussi; Durandin, Nikita; Lajunen, Tatu; Linko, Veikko; Laaksonen, Timo, 2022, Cellulose, 29, 18, 9707-9717. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Tarkenna hakuasi

Tutkimusryhmät

Projektit

Avainsanat

Julkaisut

DNA Origami Uptake in Y-79 Retinoblastoma Cells Driven by Oligolysine Coating

Effective process for screening melanin binding affinity of small molecule drugs and new drug candidates

Hyaluronic Acid Decoration Facilitates CD44‐Mediated Targeting and Alters Protein Corona Formation of Extracellular Vesicles

Light-responsive liposomes for on-demand degradation of cellulose-based hydrogels

Photothermal and photo-oxidation mediated release of lipophilic paclitaxel from liposomes: from formulation to in vitro efficacy and molecular dynamics simulations

Sustained intravitreal dissolution and kinase inhibition by an inhibitory cGMP analogue after its injection as a suspension of a poorly soluble salt

Drug release and pharmacokinetics of intravitreal liposomal injections: a case study with cyclic guanosine monophosphate derivative

Fluorescence Anisotropy for Detailed Analysis of Doxorubicin Loading into DNA Origami Nanocarriers for Drug Delivery

Harnessing liposomal nanocellulose hydrogel for NIR-light driven on-demand drug delivery

In vitro biophysical and biological profiling of commercial lipid-based dry eye products

New insights on liposomal formulations based upon tear film lipids: A combined study of safety and ocular surface pharmacokinetics

Protective Role and Enhanced Intracellular Uptake of Curcumin in Retinal Cells Using Self-Emulsifying Drug Delivery Systems (SNEDDS)

Barcode lipids for absolute quantitation of liposomes in ocular tissues

Development of Focused Ultrasound-Assisted Nanoplexes for RNA Delivery

Doxorubicin-loaded DNA origami nanostructures: stability in vitreous and their uptake and toxicity in ocular cells

PL3 CendR peptide shows specific uptake in cultured Y79 retinoblastoma cells with nucleolar accumulation

Potential of Extracellular Vesicles as Therapeutics in Retinal Diseases

Development of Robust Cationic Light-Activated Thermosensitive Liposomes: Choosing the Right Lipids

Early-Stage Development of an Anti-Evaporative Liposomal Formulation for the Potential Treatment of Dry Eyes

Establishing a simple perfusion cell culture system for light-activated liposomes

Selective drug delivery to the retinal cells: Biological barriers and avenues

Imaging, quantitation and kinetic modelling of intravitreal nanomaterials

Liposomal sunitinib for ocular drug delivery: A potential treatment for choroidal neovascularization

Nanoparticle release from anionic nanocellulose hydrogel matrix