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Capsaicin-Inspired Hydroxamate Hybrids as Selective HDAC6 Inhibitors with Antiproliferative Activity in Hematological Malignancies
Gimenez Borges, Lara; Alves, Thais Nascimento de Oliveira; Vassiliades, Sandra Valeria; Carlos, Jorge Antonio Elias Godoy; Waitman, Karoline de Barros; Hilscher, Sebastian; Schutkowski, Mike; Sippl, Wolfgang; Tavares, Maurício Temotheo; Toledo, Monica Franco Zannini Junqueira; Costa-Lotufo, Letícia Veras; Kronenberger, Thales; Machado-Neto, João Agostinho; Parise-Filho, Roberto, 2026, ACS omega, 11, 5, 8415-8430. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
Identification of an N-methylpyrazole derivative as a selective inhibitor of breast cancer resistance protein (BCRP/ABCG2)
Siridó, Andrezza Braiane Ferreira; Gomes de Oliveira, Arthur Henrique; Poletto, Julia; Kronenberger, Thales; Rego, Fabiane Gomes de Moraes; Picheth, Geraldo; Le Borgne, Marc; Boumendjel, Ahcène; Rosa, Fernanda Andreia; Valdameri, Glaucio; Moure, Vivian Rotuno, 2026, Archives of biochemistry and biophysics, 779, 110761. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
Inhibitors Targeting SARS‐CoV‐2 Papain‐Like Protease: Screening, Design, Synthesis, and Biological Evaluation
Iuga, Elena‐Oriana; Gone, Nilu; de Godoy, Mariana Ortiz; Verissimo, Gabriel Correa; de Jesus Agostinetto, Giovanna; Urich, Liam; Krüger, Nadine; Kronenberger, Thales; Guido, Rafael Victorio Carvalho; O’Donoghue, Anthony J; Laufer, Stefan A; Pillaiyar, Thanigaimalai, 2026, Chemmedchem, 21, 9, e202600007. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
Repositioning HDAC Inhibitors for Glioma Treatment: Synthesis and Biological Evaluation
Furtado, Luciana Costa; Waitman, Karoline de Barros; Silva, Nuno ATF; Gouvea, Leticia Marcelino; Kronenberger, Thales; Toledo, Mônica Franco Zannini Junqueira; Ferreira, Elthon Gois; Machado-Neto, João Agostinho; Kruyt, Frank A E; Parise Filho, Roberto; Costa-Lotufo, Letícia V, 2026, ACS omega, 11, 6, 10104-10120. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
Repurposing 6-Anilinopurine Derivatives ThatExhibit PfHDAC1 Inhibition and Antimalarial Activity against Asexualand Sexual Stages of
Dias, Barbara K. M.; Maiolini, Pedro N.; Santos, Natacha Diesca; Waitman, Karoline B.; Tavares, Mauricio T.; Verotti, Joao P. F.; Toledo, Monica F. Z. J.; Kronenberger, Thales; Parise-Filho, Roberto; Garcia, Celia R. S., 2026, ACS omega, [Epub ahead of print July 6, 2026], 1-11. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
The metabolome of an E. coli CRISPRi library identifies benefits of minimal metabolite levels and targets for engineering
Rapp, Johanna; Verhülsdonk, Andreas; Garcke, Anton; Stadelmann, Amelie; Farke, Niklas; Troßmann, Felicia; Kronenberger, Thales; Alvarado, Alejandra; Petras, Daniel; Link, Hannes, 2026, Cell systems, 17, 4, 101518. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
A Twist of Fate: The Helix–Turn–Helix Motif in Pseudomonas aeruginosa ExsA Can Allosterically Stabilize the Ligand-Binding Domain
Medarametla, Prasanthi; Greenhalgh, Jack Calum; Pöhner, Ina; Welch, Martin; Poso, Antti; Kronenberger, Thales; Rahman, Taufiq, 2025, Journal of chemical information and modeling, 65, 22, 12448-12463. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
A twist in the tale: shifting from covalent targeting of a tyrosine in JAK3 to a lysine in MK2
Hillebrand, Laura; Wang, Guiqun; Rasch, Alexander; Masberg, Benedikt; Chaikuad, Apirat; Kronenberger, Thales; Günther, Ellen; Forster, Michael; Poso, Antti; Lämmerhofer, Michael; Laufer, Stefan A.; Knapp, Stefan; Gehringer, Matthias, 2025, RSC medicinal chemistry, 16, 10, 4906-4919. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
Activation of steroid hormone receptors by metabolism-disrupting chemicals
Pitkänen, Sini; Niskanen, Jonna; Mysore, Raghavendra; Niskanen, Einari A; Palvimo, Jorma J; Pijnenburg, Dirk; van Beuningen, Rinie; Rashidian, Azam; Kronenberger, Thales; Poso, Antti; Levonen, Anna-Liisa; Küblbeck, Jenni; Honkakoski, Paavo, 2025, Toxicology and applied pharmacology, 499, 117335. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
Continuous exchange of an inner-membrane ring component is required for assembly and function of the type III secretion system
Brianceau, Corentin; Wimmi, Stephan; Kronenberger, Thales; Diepold, Andreas, 2025, Nature communications, 16, 1, 9889. A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä