Tutkimusryhmät
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Computational drug repurposing: approaches, evaluation of in silico resources and case studies
Tanoli, Ziaurrehman; Fernández-Torras, Adrià; Özcan, Umut Onur; Kushnir, Aleksandr; Nader, Kristen Michelle; Gadiya, Yojana; Fiorenza, Laura; Ianevski, Aleksandr; Vähä-Koskela, Markus; Miihkinen, Mitro; Seemab, Umair; Leinonen, Henri; Seashore-Ludlow, Brinton; Tampere, Marianna; Kalman, Adelinn; Ballante, Flavio; Benfenati, Emilio; Saunders, Gary; Potdar, Swapnil; Gómez García, Ismael; García-Serna, Ricard; Talarico, Carmine; Beccari, Andrea Rosario; Schaal, Wesley; Polo, Andrea; Costantini, Sus. 2025. Nature reviews drug discovery. 24: 521-542 A2 Katsausartikkeli tieteellisessä aikakauslehdessä -
Selection of locally administered ocular tissue-targeting RNA aptamers using in vivo SELEX
Stenberg, Katja; Korhonen, Sonja; Seemab, Umair; Dupont, Daniel Miotto; Kjems, Jørgen; Honkakoski, Paavo; Subrizi, Astrid. 2025. European journal of pharmaceutical sciences. 212: A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
A combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models
Leinonen, Henri; Zhang, Jianye; Occelli, Laurence M; Seemab, Umair; Choi, Elliot H; LP Marinho, Luis Felipe; Querubin, Janice; Kolesnikov, Alexander V; Galinska, Anna; Kordecka, Katarzyna; Hoang, Thanh; Lewandowski, Dominik; Lee, Timothy T; Einstein, Elliott E; Einstein, David E; Dong, Zhiqian; Kiser, Philip D; Blackshaw, Seth; Kefalov, Vladimir J; Tabaka, Marcin; Foik, Andrzej; Petersen-Jones, Simon M; Palczewski, Krzysztof. 2024. Nature communications. 15: . 5943 A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä -
Targeting ocular tissues with intravenously administered aptamers selected by in vivo SELEX
Korhonen, Sonja; Stenberg, Katja; Seemab, Umair; Bartos, Piia; Mäkiniemi, Katariina; Kjems, Jørgen; Dupont, Daniel Miotto; Subrizi, Astrid. 2024. Molecular therapy nucleic acids. 35: A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä