Anssi Lipponen

Low prevalence of CWH43 variants among Finnish and Norwegian idiopathic normal pressure hydrocephalus patients: a cohort-based observational study

Räsänen, Joel; Helisalmi, Seppo; Heikkinen, Sami; Raivo, Joose; Korhonen, Ville E.; Martiskainen, Henna; Junkkari, Antti; Grenier-Boley, Benjamin; Bellenguez, Céline; Oinas, Minna; Avellan, Cecilia; Frantzen, Janek; Kotkansalo, Anna; Rinne, Jaakko; Ronkainen, Antti; Kauppinen, Mikko; von und zu Fraunberg, Mikael; Lönnrot, Kimmo; Satopää, Jarno; Perola, Markus; Koivisto, Anne M.; Julkunen, Valtteri; Portaankorva, Anne M.; Mannermaa, Arto; Soininen, Hilkka; Jääskeläinen, Juha E.; Lambert, Jean-Cha. 2025. Fluids and barriers of the cns. 22: . 17 A1 Journal article (refereed), original research

Molecular and functional changes in GABAergic transmission during epileptogenesis in a rat model of post-traumatic epilepsy

Puhakka, Noora; Cifelli, Pierangelo; Ruffolo, Gabriele; Gaeta, Alessandro; Roseti, Cristina; De Iacovo, Angela; Tiilikainen, Johanna; Ndode-Ekane, Xavier Ekolle; Lipponen, Anssi; Drexel, Meinrad; Sperk, Günther; Pitkänen, Asla; Palma, Eleonora. 2025. Experimental neurology. 387: A1 Journal article (refereed), original research

Wastewater based genomic surveillance key to population level monitoring of AmpC/ESBL producing Escherichia coli

Al-Mustapha, Ahmad Ibrahim; Tiwari, Ananda; Laukkanen-Ninios, Riikka; Lehto, Kirsi-Maarit; Oikarinen, Sami; Lipponen, Anssi; Pitkänen, Tarja; Heikinheimo, Annamari; WastPan Study Group. 2025. Scientific reports. 15: . 7400 A1 Journal article (refereed), original research

Detection of SARS-COV-2 variants and their proportions in wastewater samples using next-generation sequencing in Finland

Lipponen, Anssi; Kolehmainen, Aleksi; Oikarinen, Sami; Hokajärvi, Anna-Maria; Lehto, Kirsi-Maarit; Heikinheimo, Annamari; Halkilahti, Jani; Juutinen, Aapo; Luomala, Oskari; Smura, Teemu; Liitsola, Kirsi; Blomqvist, Soile; Savolainen-Kopra, Carita; Pitkänen, Tarja; Länsivaara, Annika; Hyder, Rafiqul; Janhonen, Erja; Heikinheimo, Annamari; Heljanko, Viivi; Johansson, Venla; Kurittu, Paula; Tiwari, Ananda; Al-Mustapha, Ahmad; Sarekoski, Anniina; Möttönen, Teemu; Räisänen, Kati; Savolainen-Kopra, Ca. 2024. Scientific reports. 14: . 7751 A1 Journal article (refereed), original research

Risk Variants Associated With Normal Pressure Hydrocephalus: Genome-Wide Association Study in the FinnGen Cohort

Räsänen, Joel; Heikkinen, Sami; Mäklin, Kiira; Lipponen, Anssi; Kuulasmaa, Teemu; Mehtonen, Juha; Korhonen, Ville E; Junkkari, Antti; Grenier-Boley, Benjamin; Bellenguez, Celine; Oinas, Minna; Avellan, Cecilia; Frantzén, Janek; Kotkansalo, Anna; Rinne, Jaakko; Ronkainen, Antti; Kauppinen, Mikko; von und zu Fraunberg, Mikael; Lönnrot, Kimmo; Satopää, Jarno; Perola, Markus; Koivisto, Anne M; Julkunen, Valtteri; Portaankorva, Anne M; Mannermaa, Arto; Soininen, Hilkka; Helisalmi, Seppo; Jääskeläinen. 2024. Neurology. 103: A1 Journal article (refereed), original research

The effects of RT-qPCR standards on reproducibility and comparability in monitoring SARS-CoV-2 levels in wastewater

Juutinen, Aapo; Tiwari, Ananda; Hokajärvi, Anna-Maria; Luomala, Oskari; Kolehmainen, Aleksi; Nurmi, Eveliina; Salmivirta, Elisa; Pitkänen, Tarja; Lipponen, Anssi. 2024. Scientific reports. 14: . 25582 A1 Journal article (refereed), original research

Gene Expression Profile as a Predictor of Seizure Liability

Lipponen, Anssi; Kajevu, Natallie; Natunen, Teemu; Ciszek, Robert; Puhakka, Noora; Hiltunen, Mikko; Pitkänen, Asla. 2023. International journal of molecular sciences. 24: A1 Journal article (refereed), original research

Treatment of Status Epilepticus after Traumatic Brain Injury Using an Antiseizure Drug Combined with a Tissue Recovery Enhancer Revealed by Systems Biology

Kajevu, Natallie; Lipponen, Anssi; Andrade, Pedro; Bañuelos, Ivette; Puhakka, Noora; Hämäläinen, Elina; Natunen, Teemu; Hiltunen, Mikko; Pitkänen, Asla. 2023. International journal of molecular sciences. 24: . 14049 A1 Journal article (refereed), original research

Regulation of parvalbumin interactome in the perilesional cortex after experimental traumatic brain injury

Hiltunen, Johanna; Ndode-Ekane, Xavier Ekolle; Lipponen, Anssi; Drexel, Meinrad; Sperk, Günther; Puhakka, Noora; Pitkänen, Asla. 2021. Neuroscience

A systems biology approach for identification and stepwise validation of pharmacotherapy candidates for traumatic brain injury

Lipponen, Anssi. 2020. Publications of the University of Eastern Finland. Dissertations in Health Sciences

Plau/Plaur double-deficiency did not worsen lesion severity or vascular integrity after traumatic brain injury

Kyyriäinen, Jenni; Tapiala, Jesse; Lipponen, Anssi; Ekolle Ndode-Ekane, Xavier; Pitkänen, Asla. 2020. Neuroscience letters

Deficiency of urokinase-type plasminogen activator and its receptor affects social behavior and increases seizure susceptibility

Kyyriäinen, J; Bolkvadze, T; Koivisto, H; Lipponen, A; Pérez, LO; Ekolle Ndode-Ekane, X; Tanila, H; Pitkänen, A. 2019. Epilepsy research

Dynamics of clusterin protein expression in the brain and plasma following experimental traumatic brain injury

Das Gupta, S; Lipponen, A; Paldanius, KMA; Puhakka, N; Pitkänen, A. 2019. Scientific reports

Extracellular Vesicles as Diagnostics and Therapeutics for Structural Epilepsies

Karttunen, J; Heiskanen, M; Lipponen, A; Poulsen, D; Pitkänen, A. 2019. International journal of molecular sciences

In Vitro and In Vivo Pipeline for Validation of Disease-Modifying Effects of Systems Biology-Derived Network Treatments for Traumatic Brain Injury - Lessons Learned

Lipponen, A; Natunen, T; Hujo, M; Ciszek, R; Hämäläinen, E; Tohka, J; Hiltunen, M; Paananen, J; Poulsen, D; Kansanen, E; Ekolle Ndode-Ekane, X; Levonen, AL; Pitkänen, A. 2019. International journal of molecular sciences

Age- and quality-dependent DNA methylation correlate with melanin-based coloration in a wild bird

Soulsbury, Carl D; Lipponen, Anssi; Wood, Kristie; Mein, Charles A; Hoffman, Joseph I; Lebigre, Christophe. 2018. Ecology and evolution

Effect of resource availability on evolution of virulence and competition in an environmentally transmitted pathogen

Pulkkinen, Katja; Pekkala, Nina; Ashrafi, Roghaieh; Hämäläinen, Dorrit M; Nkembeng, Aloysius N; Lipponen, Anssi; Hiltunen, Teppo; Valkonen, Janne K; Taskinen, Jouni. 2018. Fems microbiology ecology

Precipitation-based extracellular vesicle isolation from rat plasma co-precipitate vesicle-free microRNAs

Karttunen, Jenni; Heiskanen, Mette; Navarro-Ferrandis, Vicente; Das Gupta, Shalini; Lipponen, Anssi; Puhakka, Noora; Rilla, Kirsi; Koistinen, Arto; Pitkänen, Asla. 2018. Journal of extracellular vesicles

Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury

Lipponen, Anssi; El-Osta, Assam; Kaspi, Antony; Ziemann, Mark; Khurana, Ishant; Harikrishnan, K N; Navarro-Ferrandis, Vicente; Puhakka, Noora; Paananen, Jussi; Pitkänen, Asla. 2018. Acta neuropathologica communications

Analysis of Post-Traumatic Brain Injury Gene Expression Signature Reveals Tubulins, Nfe2l2, Nfkb, Cd44, and S100a4 as Treatment Targets

Lipponen Anssi, Paananen Jussi, Puhakka Noora, Pitkänen Asla. 2016. Scientific reports

High Nutrient Concentration Can Induce Virulence Factor Expression and Cause Higher Virulence in an Environmentally Transmitted Pathogen

Penttinen Reetta, Kinnula Hanna, Lipponen Anssi, Bamford Jaana KH, Sundberg Lotta-Riina. 2016. Microbial ecology

Gender issues in antiepileptogenic treatments

Pitkänen A, Huusko N, Ndode-Ekane XE, Kyyriäinen J, Lipponen A, Lipsanen A, Sierra A, Bolkvadze T. 2014. Neurobiology of disease

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Low prevalence of CWH43 variants among Finnish and Norwegian idiopathic normal pressure hydrocephalus patients: a cohort-based observational study

Molecular and functional changes in GABAergic transmission during epileptogenesis in a rat model of post-traumatic epilepsy

Wastewater based genomic surveillance key to population level monitoring of AmpC/ESBL producing Escherichia coli

Detection of SARS-COV-2 variants and their proportions in wastewater samples using next-generation sequencing in Finland

Risk Variants Associated With Normal Pressure Hydrocephalus: Genome-Wide Association Study in the FinnGen Cohort

The effects of RT-qPCR standards on reproducibility and comparability in monitoring SARS-CoV-2 levels in wastewater

Gene Expression Profile as a Predictor of Seizure Liability

Treatment of Status Epilepticus after Traumatic Brain Injury Using an Antiseizure Drug Combined with a Tissue Recovery Enhancer Revealed by Systems Biology

Regulation of parvalbumin interactome in the perilesional cortex after experimental traumatic brain injury

A systems biology approach for identification and stepwise validation of pharmacotherapy candidates for traumatic brain injury

Plau/Plaur double-deficiency did not worsen lesion severity or vascular integrity after traumatic brain injury

Deficiency of urokinase-type plasminogen activator and its receptor affects social behavior and increases seizure susceptibility

Dynamics of clusterin protein expression in the brain and plasma following experimental traumatic brain injury

Extracellular Vesicles as Diagnostics and Therapeutics for Structural Epilepsies

In Vitro and In Vivo Pipeline for Validation of Disease-Modifying Effects of Systems Biology-Derived Network Treatments for Traumatic Brain Injury - Lessons Learned

Age- and quality-dependent DNA methylation correlate with melanin-based coloration in a wild bird

Effect of resource availability on evolution of virulence and competition in an environmentally transmitted pathogen

Precipitation-based extracellular vesicle isolation from rat plasma co-precipitate vesicle-free microRNAs

Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury

Analysis of Post-Traumatic Brain Injury Gene Expression Signature Reveals Tubulins, Nfe2l2, Nfkb, Cd44, and S100a4 as Treatment Targets

High Nutrient Concentration Can Induce Virulence Factor Expression and Cause Higher Virulence in an Environmentally Transmitted Pathogen

Gender issues in antiepileptogenic treatments