Elias Ylä-Herttuala

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Information Publications

Currently working as an Adjunct Professor to develop advanced cardiac MRI methods and molecular MRI for the characterization of different cardiovascular diseases. I am leading the cardiac imaging group (MRI-, hyperpolariztion MRI-field, PET/CT, PET/MR, SPECT, microCT) at AIV-institute at UEF and leading couple of clinical cardiovascular imaging research projects with advanced methods in Kuopio University Hospital.

Research groups

Modern methods in cardiac imaging (MOMESY)
Cardiovascular imaging and predictive markers 01.01.2022 -
Cardiac imaging group 02.08.2021 -

Keywords

cardiovascular diseases magnetic resonance imaging (MRI) medical imaging multimodality medical imaging quantitative imaging

Publications

28/28 items

Characterization of Inflammation in In Vivo Mouse Myocardium Using Longitudinal Rotating Frame Relaxation Time (T1ρ) and T2 Relaxation Time Maps
Ylä‐Herttuala, Elias; Mustafa, Haja Sherief Nazimutheen; Khan, Muhammad Arsalan; Merentie, Mari; Wirth, Galina; Laidinen, Svetlana; Holappa, Lari; Ylä‐Herttuala, Seppo; Liimatainen, Timo, 2026, Nmr in biomedicine, 39, 6, e70304. A1 Journal article (refereed), original research
Enhancing MRI contrast between sub-chronic myocardial infarct, remote and healthy myocardium using periodic irradiation in the rotating frames
Ylä-Herttuala, Elias; Räty, Iida; Montaser, Ahmed; Laidinen, Svetlana; Michaeli, Shalom; Liimatainen, Timo, 2026, Scientific reports, 16, 3888. A1 Journal article (refereed), original research
Rotating Frame Spin‐Lock Cardiac MRI> Method at 9.4 T Can Characterize Diffuse Fibrosis in Progressing Hypertensive Heart Disease in Mice
Kiviluoto, Riku; Törmä, Diana; Tawfek, Ahmed; Leikas, Aleksi; Räihä, Eetu; Merentie, Mari; Ruotsalainen, Anna‐Kaisa; Ylä‐Herttuala, Seppo; Ylä‐Herttuala, Elias, 2026, Magnetic resonance in medicine, [First published: 14 October 2026], 1-13. A1 Journal article (refereed), original research
Simultaneous 3‐D Adiabatic T1ρ, T2*, and Quantitative Susceptibility Mapping for Characterization of Myocardial Infarction in Ex Vivo Mouse
Räty, Iida; Nykänen, Olli; Kettunen, Sanna; Laidinen, Svetlana; Ruotsalainen, Anna‐Kaisa; Nissi, Mikko J; Ylä‐Herttuala, Elias, 2026, Nmr in biomedicine, 39, 10, e70378. A1 Journal article (refereed), original research
The effect of age and sex on T1, T2, and T2* relaxation time constants in cardiac MRI in healthy Finnish population
Liukkonen, Mimmi K; Jämsä, Miska; Hartikainen, Suvi; Husso, Minna; Hedman, Marja; Hietanen, Heikki; Ugander, Martin; Sillanmäki, Saara; Ylä-Herttuala, Elias, 2026, Acta radiologica open, 15, 1, 1-12. A1 Journal article (refereed), original research
Capturing Acute and Subchronic Myocardial Infarct by MRI Rotating Frame Relaxation Times in Mice In and Ex Vivo
Ylä-Herttuala, Elias; Laakso, Hanne; Khan, Muhammad Arsalan; Laidinen, Svetlana; Heikura, Tommi; Ylä-Herttuala, Seppo; Liimatainen, Timo, 2025, Nmr in biomedicine, 38, 6, e70061. A1 Journal article (refereed), original research
Myocardial infarction activates the 9p21.3 orthologous locus expression, but its absence does not alter cardiac pathophysiology in ischemia
Kettunen, Sanna; Slita, Anna; Suoranta, Tuisku; Räty, Iida; Laidinen, Svetlana; Ylä‐Herttuala, Elias; Ruotsalainen, Anna‐Kaisa; Ylä‐Herttuala, Seppo, 2025, Physiological reports, 13, 10, 1-15. A1 Journal article (refereed), original research
Sydänlihaksen koostumuksen arviointi T1, T2- ja T2*-magneettikuvamisen avulla
Jämsä, Miska; Liukkonen, Mimmi; Ylä-Herttuala, Elias; Sillanmäki, Saara, 2025, Sydänääni, 36, 3, 358-362. D1 Article in a trade journal
Uudet sydänlihaksen fibroosia ja supistumista arvioivat magneettikuvausmenetelmät sydämen vajaatoiminnan diagnostiikassa
Iso-Mustajärvi, Saara; Ylä-Herttuala, Elias; Hedman, Marja; Sillanmäki, Saara, 2025, Sydänääni, 36, 3, 350-356. D1 Article in a trade journal
Deletion of the Murine Ortholog of the Human 9p21.3 Locus Leads to Insulin Resistance and Obesity in Hypercholesterolemic Mice
Kettunen, Sanna; Suoranta, Tuisku; Beikverdi, Sadegh; Heikkilä, Minja; Slita, Anna; Räty, Iida; Ylä-Herttuala, Elias; Öörni, Katariina; Ruotsalainen, Anna-Kaisa; Ylä-Herttuala, Seppo, 2024, Cells, 13, 11, 983. A1 Journal article (refereed), original research
Ex vivo imaging of subacute myocardial infarction with ultra-short echo time 3D quantitative T1- and T1ρ-mapping magnetic resonance imaging in mice
Räty, Iida; Aarnio, Antti; Nissi, Mikko J; Kettunen, Sanna; Ruotsalainen, Anna-Kaisa; Laidinen, Svetlana; Ylä-Herttuala, Seppo; Ylä-Herttuala, Elias, 2024, European heart journal : imaging methods and practice, 3, 1, 1-10. A1 Journal article (refereed), original research
Repaired coarctation of the aorta does not affect four-dimensional flow metrics in bicuspid aortic valve disease
Kiljander, Teemu; Kauhanen, Petteri; Sillanmäki, Saara; Lottonen-Raikaslehto, Line; Husso, Minna; Ylä-Herttuala, Elias; Saari, Petri; Kokkonen, Jorma; Laukkanen, Jari; Mustonen, Pirjo; Hedman, Marja, 2024, Interdisciplinary cardiovascular and thoracic surgery, 38, 5, ivae086. A1 Journal article (refereed), original research
Review of Myocardial Ischemia, Scar, and Viability Estimation with Molecular Magnetic Resonance Imaging
Sillanmäki, Saara; Hartikainen, Suvi; Ylä-Herttuala, Elias, 2024, Biomedicines, 12, 8, 1681. A2 Review article, Literature review, Systematic review
4D Flow Versus 2D Phase Contrast MRI in Populations With Bi- and Tricuspid Aortic Valves
Hautanen, S; Kiljander, T; Korpela, T; Saari, P; Kokkonen, J; Mustonen, P; Sillanmäki, S; Ylä-Herttuala, E; Husso, M; Hedman, M; Kauhanen, P, 2023, In vivo, 37, 1, 88-98. A1 Journal article (refereed), original research
Lymphatic insufficiency leads to distinct myocardial infarct content assessed by magnetic resonance TRAFFn, T1ρ and T2 relaxation times
Ylä-Herttuala, Elias; Vuorio, Taina; Kettunen, Sanna; Laidinen, Svetlana; Ylä-Herttuala, Seppo; Liimatainen, Timo, 2023, Scientific reports, 13, 1579. A1 Journal article (refereed), original research
Measuring Cardiac Dyssynchrony with DENSE (Displacement Encoding with Stimulated Echoes)—A Systematic Review
Sillanmäki, Saara; Vainio, Hanna Liina; Ylä-Herttuala, Elias; Husso, Minna; Hedman, Marja, 2023, Reviews in cardiovascular medicine, 24, 9, 261. A2 Review article, Literature review, Systematic review
AAV8-mediated sVEGFR2 and sVEGFR3 gene therapy combined with chemotherapy reduces the growth and microvasculature of human ovarian cancer and prolongs the survival in mice
Kujala, Anni; Valkonen, Elina; Sallinen, Hanna; Tuppurainen, Laura; Laakso, Hanne; Ylä-Herttuala, Elias; Liimatainen, Timo; Kujala, Jouni; Jokelainen, Otto; Sironen, Reijo; Anttila, Maarit; Ylä-Herttuala, Seppo, 2022, Frontiers in medicine, 9, 1018208. A1 Journal article (refereed), original research
Docetaxel chemotherapy response in PC3 prostate cancer mouse model detected by rotating frame relaxations and water diffusion
Laakso, Hanne; Ylä-Herttuala, Elias; Sierra, Alejandra; Jambor, Ivan; Poutanen, Matti; Liljenbäck, Heidi; Virtanen, Helena; Merisaari, Harri; Aronen, Hannu; Minn, Heikki; Roivainen, Anne; Liimatainen, Timo, 2021, Nmr in biomedicine, 34, 4, e4483. A1 Journal article (refereed), original research
Characterizing myocardial infarction using novel magnetic resonance imaging tools : a comparison between a normal and an insufficient lymphatic circulation
Ylä-Herttuala, Elias, 2020, Publications of the University of Eastern Finland. Dissertations in Health Sciences. G5 Doctoral dissertation (article)
Relaxation along fictitious field with rank n (RAFFn): A promising magnetic resonance imaging method to determine myocardial infarction
Ylä-Herttuala, Elias; Mirmojarabian, Amir; Liimatainen, Timo, 2020, Interventional cardiology, 13, 1, 222-228. A2 Review article, Literature review, Systematic review
Characterizing valve dynamics in mice by high-resolution cine-MRI
Weisell, J; Ruotsalainen, AK; Laakso, H; Ylä-Herttuala, E; Näpänkangas, J; Levonen, AL; Liimatainen, T; Rysä, J, 2019, Nmr in biomedicine, 32, 8, e4108. A1 Journal article (refereed), original research
Molecular Imaging to Monitor Left Ventricular Remodeling in Heart Failure
Ylä-Herttuala, Elias; Saraste, Antti; Knuuti, Juhani; Liimatainen, Timo; Ylä-Herttuala, Seppo, 2019, Current cardiovascular imaging reports, 12, 4, 11. A2 Review article, Literature review, Systematic review
Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction
Vuorio, Taina; Ylä-Herttuala, Elias; Laakkonen, Johanna P; Laidinen, Svetlana; Liimatainen, Timo; Ylä-Herttuala, Seppo, 2018, Scientific reports, 8, 16709. A1 Journal article (refereed), original research
Quantification of myocardial infarct area based on TRAFFn relaxation time maps - comparison with cardiovascular magnetic resonance late gadolinium enhancement, T1p and T2 in vivo
Ylä-Herttuala, Elias ; Laidinen, Svetlana; Laakso, Hanne; Liimatainen, Timo, 2018, Journal of cardiovascular magnetic resonance, 20, 34. A1 Journal article (refereed), original research
T-2, T-1rho and T-RAFF4 detect early regenerative changes in mouse ischemic skeletal muscle
Laakso, Hanne; Wirth, Galina; Korpisalo, Petra; Ylä-Herttuala, Elias; Michaeli, Shalom; Ylä-Herttuala, Seppo; Liimatainen, Timo, 2018, Nmr in biomedicine, 31, 5, e3909. A1 Journal article (refereed), original research
Aggravated post-infarct heart failure in type 2 diabetes is associated with impaired mitophagy and exaggerated inflammasome activation
Durga Devi T, Babu M, Mäkinen P, Kaikkonen M, Heinaniemi M, Laakso H, Ylä-Herttuala E, Rieppo L, Liimatainen T, Naumenko N,Tavi P, Ylä-Herttuala S, 2017, American journal of pathology, 187, 12, 2659-2673. A1 Journal article (refereed), original research
Functional MRI Measurements to Predict Early Adenoviral Gene Therapy Response in Ovarian Cancer Mouse Model
Tuppurainen L, Sallinen H, Hakkarainen H, Liimatainen T, Hassan M, Ylä-Herttuala E, Anttila M, Hämäläinen K, Veli-Matti Kosma, Heinonen S, Alitalo K, Ylä-Herttuala S, 2013, Journal of genetic syndromes & gene therapy, 4, 8, x-x. A1 Journal article (refereed), original research
Longitudinal rotating frame relaxation time measurements in infarcted mouse myocardium in vivo
Musthafa HS, Dragneva G, Lottonen L, Merentie M, Petrov L, Heikura T, Ylä-Herttuala E, Ylä-Herttuala S, Gröhn O, Liimatainen T, 2012, Magnetic resonance in medicine, 2012 Jun 26, [Epub ahead of print]. A1 Journal article (refereed), original research

Refine your search

Elias Ylä-Herttuala

Research groups

Keywords

Characterization of Inflammation in In Vivo Mouse Myocardium Using Longitudinal Rotating Frame Relaxation Time (T1ρ) and T2 Relaxation Time Maps

Enhancing MRI contrast between sub-chronic myocardial infarct, remote and healthy myocardium using periodic irradiation in the rotating frames

Rotating Frame Spin‐Lock Cardiac MRI> Method at 9.4 T Can Characterize Diffuse Fibrosis in Progressing Hypertensive Heart Disease in Mice

Simultaneous 3‐D Adiabatic T1ρ, T2*, and Quantitative Susceptibility Mapping for Characterization of Myocardial Infarction in Ex Vivo Mouse

The effect of age and sex on T1, T2, and T2* relaxation time constants in cardiac MRI in healthy Finnish population

Capturing Acute and Subchronic Myocardial Infarct by MRI Rotating Frame Relaxation Times in Mice In and Ex Vivo

Myocardial infarction activates the 9p21.3 orthologous locus expression, but its absence does not alter cardiac pathophysiology in ischemia

Sydänlihaksen koostumuksen arviointi T1, T2- ja T2*-magneettikuvamisen avulla

Uudet sydänlihaksen fibroosia ja supistumista arvioivat magneettikuvausmenetelmät sydämen vajaatoiminnan diagnostiikassa

Deletion of the Murine Ortholog of the Human 9p21.3 Locus Leads to Insulin Resistance and Obesity in Hypercholesterolemic Mice

Ex vivo imaging of subacute myocardial infarction with ultra-short echo time 3D quantitative T1- and T1ρ-mapping magnetic resonance imaging in mice

Repaired coarctation of the aorta does not affect four-dimensional flow metrics in bicuspid aortic valve disease

Review of Myocardial Ischemia, Scar, and Viability Estimation with Molecular Magnetic Resonance Imaging

4D Flow Versus 2D Phase Contrast MRI in Populations With Bi- and Tricuspid Aortic Valves

Lymphatic insufficiency leads to distinct myocardial infarct content assessed by magnetic resonance TRAFFn, T1ρ and T2 relaxation times

Measuring Cardiac Dyssynchrony with DENSE (Displacement Encoding with Stimulated Echoes)—A Systematic Review

AAV8-mediated sVEGFR2 and sVEGFR3 gene therapy combined with chemotherapy reduces the growth and microvasculature of human ovarian cancer and prolongs the survival in mice

Docetaxel chemotherapy response in PC3 prostate cancer mouse model detected by rotating frame relaxations and water diffusion

Characterizing myocardial infarction using novel magnetic resonance imaging tools : a comparison between a normal and an insufficient lymphatic circulation

Relaxation along fictitious field with rank n (RAFFn): A promising magnetic resonance imaging method to determine myocardial infarction

Characterizing valve dynamics in mice by high-resolution cine-MRI

Molecular Imaging to Monitor Left Ventricular Remodeling in Heart Failure

Downregulation of VEGFR3 signaling alters cardiac lymphatic vessel organization and leads to a higher mortality after acute myocardial infarction

Quantification of myocardial infarct area based on TRAFFn relaxation time maps - comparison with cardiovascular magnetic resonance late gadolinium enhancement, T1p and T2 in vivo

T-2, T-1rho and T-RAFF4 detect early regenerative changes in mouse ischemic skeletal muscle

Aggravated post-infarct heart failure in type 2 diabetes is associated with impaired mitophagy and exaggerated inflammasome activation

Functional MRI Measurements to Predict Early Adenoviral Gene Therapy Response in Ovarian Cancer Mouse Model

Longitudinal rotating frame relaxation time measurements in infarcted mouse myocardium in vivo