
EDCMET
Project
01.01.2019 - 31.12.2023
A.I. Virtanen Institute for Molecular Sciences, Faculty of Health Sciences
Institute of Biomedicine, School of Medicine, Faculty of Health Sciences
School of Pharmacy, Faculty of Health Sciences
Funders
Main funder
European Comission

Metabolic effects of Endocrine Disrupting Chemicals: novel testing METhods and adverse outcome pathways
Leaders
Group description
The EDCMET project connects experts in various research fields, including systems toxicologists, experimental biologists with a thorough understanding of the molecular mechanisms of metabolic disease and comprehensive in vitro and in vivo methodological skills and ultimately, epidemiologists linking environmental exposure to adverse metabolic outcomes. Together we aim to develop novel validated test methods and models to assess the metabolic effects of endocrine disrupting compounds and to identify molecular initiating events linked to adverse outcomes.
Cooperation
Leaders
Professors
-
Paavo Honkakoski
ProfessorFaculty of Health Sciences, School of Pharmacy -
Jorma Palvimo
ProfessorSchool of Medicine, Biomedicine -
Jaana Rysä
ProfessorFaculty of Health Sciences, School of Pharmacy -
Antti Poso
ProfessorFaculty of Health Sciences, School of Pharmacy
Senior Researchers
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Vittorio Fortino
Academy Research FellowSchool of Medicine, Biomedicine -
Jenni Küblbeck
Senior ResearcherFaculty of Health Sciences, A.I. Virtanen Institute for Molecular Sciences -
Olli Kärkkäinen
Senior ResearcherFaculty of Health Sciences, School of Pharmacy
Post-doctoral Researchers
Doctoral Researchers
Supporting Staff
Publications
3 items-
A toxicogenomic data space for system-level understanding and prediction of EDC-induced toxicity
Sakhteman, A; Failli, M; Kublbeck, J; Levonen, AL; Fortino, V. 2021. Environment international. 156: 106751 A1 Journal article (refereed), original research -
Metabolism-Disrupting Chemicals and the Constitutive Androstane Receptor CAR
Küblbeck, Jenni; Niskanen, Jonna; Honkakoski, Paavo. 2020. Cells. 9: 2306 A2 Review article, Literature review, Systematic review -
The EDCMET project: Metabolic effects of endocrine disruptors
Küblbeck, Jenni; Vuorio, Taina; Niskanen, Jonna; Fortino, Vittorio; Braeunin, Albert; Abass, Khaled; Rautio, Arja; Hakkola, Jukka; Honkakoski, Paavo; Levonen, Anna-Liisa. 2020. International journal of molecular sciences. 21: 3021 A1 Journal article (refereed), original research