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Freeze-drying of biologicals´s Profile image

Freeze-drying of biologicals

Research group
01.01.2010 -
School of Pharmacy, Faculty of Health Sciences

In many cases, the stability of biological drugs (petides, proteins, vaccines etc.) is poor in solutions. In order to increase the stability of biologicals freeze-drying is used to transform solutions into the solid dosage forms with stabilizing excipients. Our freeze-drying research has mostly focused on the optimization of freeze-drying formulations and process parameters. We have facilities to perform the formulation and process optimization of freeze-drying from the microliter scale to over thousand vials with the instrumented pilot-scale freeze-dryer.