Real-world Evidence Team
We develop, validate and implement methods and approaches for evaluating effectiveness and safety of treatments by using real-world data, and also work on risk factors for conditions with long onset period.
The applied data ranges from national register-based studies to multi- and single-centre studies using data from electronic medical records and medical reports as well as data collected specifically for research purposes. We work with native data and data converted to different common data models.
The applied methods range from traditional statistical methods to machine learning. We work in close collaboration with clinicians and have extensive collaboration network, both nationally (e.g., VTT, THL, University of Turku and University of Oulu) and internationally (e.g., Hong Kong University, Monash University, London School of Economics and Political Science, Aarhus University, Karolinska Institutet).
Cooperation
Keywords
Professors
Senior Researchers
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Isabell Rumrich
Postdoctoral ResearcherSchool of Pharmacy, Faculty of Health Sciences -
Marjaana Koponen
University LecturerSchool of Pharmacy, Faculty of Health Sciences
Post-doctoral Researchers
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Anne Paakinaho
Postdoctoral ResearcherSchool of Pharmacy, Faculty of Health Sciences -
Thuan Vo
Project ResearcherSchool of Pharmacy, Faculty of Health Sciences
Doctoral Researchers
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Blair Rajamäki
Postdoctoral ResearcherSchool of Pharmacy, Faculty of Health Sciences -
Barkat Babar
Doctoral Researcher -
Eeva Pylkkö
Project ResearcherSchool of Pharmacy, Faculty of Health Sciences
Other group members
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Heli Järvinen, PhD student
Publications
159 items-
Changes in Stress Urinary Incontinence Symptoms after Pelvic Organ Prolapse Surgery: a Nationwide Cohort Study (FINPOP)
Karjalainen, Päivi K; Tolppanen, Anna-Maija; Wihersaari, Olga; Nieminen, Kari; Mattsson, Nina K; Jalkanen, Jyrki T. 2024. International urogynecology journal. 35: 909-919 -
Disease-modifying antirheumatic drugs and inhaled β2-adrenoceptor agonists and risk of Parkinson’s disease: a nationwide register-based study
Paakinaho, Anne. 2024. Publications of the University of Eastern Finland. Dissertations in Health Sciences -
Statin use and the risk of Parkinson's disease in persons with diabetes: A nested case–control study
Honkamaa, Kim; Paakinaho, Anne; Tolppanen, Anna-Maija; Kettunen, Raimo; Hartikainen, Sirpa; Tiihonen, Miia. 2024. British journal of clinical pharmacology. 90: 1463-1470 -
Agreement between physician- and patient-reported Canadian cardiovascular society scores among patients undergoing elective coronary angiography–The CATS study
Lavikainen, Piia; Hartikainen, Juha; Miettinen, Heikki; Viljakainen, Marketta; Martikainen, Janne; Tolppanen, Anna-Maija; Roine, Risto P. 2023. PLoS ONE. 18: -
Association of Personal Wealth Indicators and Health Care Costs in Persons With Alzheimer's Disease
Jarroch, Rand; Hartikainen, Sirpa; Kauhanen, Jussi; Knapp, Martin; Tolppanen, Anna-Maija. 2023. Journal of the american medical directors association. 24: 1974-1980 -
Cross-Regional Data Initiative for the Assessment and Development of Treatment for Neurological and Mental Disorders
Tsai, Daniel Hsiang Te; Bell, J. Simon; Abtahi, Shahab; Baak, Brenda N.; Bazelier, Marloes T; Brauer, Ruth; Chan, Adrienne YL; Chan, Esther W; Chen, Haoqian; Chui, Celine SL; Cook, Sharon; Crystal, Stephen; Gandhi, Poonam; Hartikainen, Sirpa; Ho, Frederick K; Hsu, Shao Ti; Ilomäki, Jenni; Kim, Ju Hwan; Klungel, Olaf H; Koponen, Marjaana; Lau, Wallis CY; Lau, Kui Kai; Lum, Terry YS; Luo, Hao; Man, Kenneth KC; Pell, Jill P; Setoguchi, Soko; Shao, Shih Chieh; Shen, Chin Yao; Shin, Ju Young; Souvere. 2023. Clinical epidemiology. 15: 1241-1252 -
Diagnostic groups of hospital stays and outpatient visits during 10 years before Alzheimer’s disease
Mäklin, Kiira; Lampela, Pasi; Lin, Julian; Sirpa, Hartikainen; Tolppanen, Anna-Maija. 2023. Bmc health services research. 23: . 339 -
Global epidemiology of hip fractures: secular trends in incidence rate, post‐fracture treatment, and all‐cause mortality
Sing, Chor‐Wing; Lin, Tzu‐Chieh; Bartholomew, Sharon; J, Simon Bell; Bennett, Corina; Beyene, Kebede; Bosco‐Levy, Pauline; Bradbury, Brian D; Chan, Amy Hai Yan; Chandran, Manju; Cooper, Cyrus; de Ridder, Maria; Y, Caroline Doyon; Droz‐Perroteau, Cécile; Ganesan, Ganga; Hartikainen, Sirpa; Ilomaki, Jenni; Jeong, Han Eol; Kiel, Douglas P; Kubota, Kiyoshi; Chia‐Cheng Lai, Edward; Lange, Jeff L; Lewiecki, E Michael; Lin, Julian; Liu, Jiannong; Maskell, Joe; de Abreu, Mirhelen Mendes; O'Kelly, James;. 2023. Journal of bone and mineral research. 38: 1064-1075 -
Hospitalization and the Risk of Initiation of Antipsychotics in Persons With Parkinson's Disease
Pirttilä, Aki; Tiihonen, Miia; Paakinaho, Anne; Hartikainen, Sirpa; Tolppanen, Anna-Maija. 2023. Journal of the american medical directors association. 24: 1290-1296.e4 -
Letter in response to Cole-Hunter et al., 2023: What does "Parkinson's disease mortality" mean?
Rumrich, Isabell Katharina; Kaasinen, Valtteri; Hänninen, Otto; Hartikainen, Sirpa; Tolppanen, Anna Maija. 2023. Environment international. 173: 107852