Einari Niskanen - UEFConnect

Central role of SUMOylation in the regulation of chromatin interactions and transcriptional outputs of the androgen receptor in prostate cancer cells

Launonen, Kaisa-Mari; Varis, Vera; Aaltonen, Niina; Niskanen, Einari A; Varjosalo, Markku; Paakinaho, Ville; Palvimo, Jorma J. 2024. Nucleic acids research. 52: 9519-9535 A1 Journal article (refereed), original research

Secreted factors from M1 macrophages drive prostate cancer stem cell plasticity by upregulating NANOG, SOX2, and CD44 through NFκB-signaling

Kainulainen, Kirsi; Niskanen, Einari A; Kinnunen, Johanna; Mäki-Mantila, Kaisa; Hartikainen, Kiia; Paakinaho, Ville; Malinen, Marjo; Ketola, Kirsi; Pasonen-Seppänen, Sanna. 2024. Oncoimmunology. 13: . 2393442 A1 Journal article (refereed), original research

Steroidireseptorien säätely

Paakinaho, Ville; Niskanen, Einari A. 2024. Duodecim. 140: 759-767 A2 Review article, Literature review, Systematic review

Chromatin accessibility and pioneer factor FOXA1 restrict glucocorticoid receptor action in prostate cancer

Helminen, Laura; Huttunen, Jasmin; Tulonen, Melina; Aaltonen, Niina; Niskanen, Einari A; Palvimo, Jorma J; Paakinaho, Ville. 2023. Nucleic acids research. 2024; 52: 625-642 A1 Journal article (refereed), original research

Complementary analysis of proteome‐wide proteomics reveals changes in RNA binding protein‐profiles during prostate cancer progression

Aikio, Erika; Koivukoski, Sonja; Kallio, Elina; Sadeesh, Nithin; Niskanen, Einari A; Latonen, Leena. 2023. Cancer reports. 6: A1 Journal article (refereed), original research

Genetic variation is a key determinant of chromatin accessibility and drives differences in the regulatory landscape of C57BL/6J and 129S1/SvImJ mice

Mononen, Juho; Taipale, Mari; Malinen, Marjo; Velidendla, Bharadwaja; Niskanen, Einari; Levonen, Anna-Liisa; Ruotsalainen, Anna-Kaisa; Heikkinen, Sami. 2023. Nucleic acids research. 2024; 52: 2904-2923 A1 Journal article (refereed), original research

International Online Team-Based Learning in Higher Education of Biomedicine - Evaluation by Learning Analytics

Mairinoja, Laura; López-Pernas, Sonsoles; Elmoazen, Ramy; Niskanen, Einari A.; Kuningas, Tiina; Wärri, Anni; Saqr, Mohammed; Strauss, Leena. Teoksessa: Elmoazen, Ramy; López-Pernas, Sonsoles; Misiejuk, Kamila; Khalil, Mohammad; Wasson, Barbara; Saqr, Mohammed(toim.) , 2023. Proceedings of the Technology-Enhanced Learning in Laboratories Workshop (TELL 2023). s. 49-60. A4 Conference proceedings

Parvovirus nonstructural protein 2 interacts with chromatin-regulating cellular proteins

Mattola, Salla; Salokas, Kari; Aho, Vesa; Mäntylä, Elina; Salminen, Sami; Hakanen, Satu; Niskanen, Einari A.; Svirskaite, Julija; Ihalainen, Teemu O.; Airenne, Kari J.; Kaikkonen-Määttä, Minna; Parrish, Colin R.; Varjosalo, Markku; Vihinen-Ranta, Maija. 2022. PLoS pathogens. 18: A1 Journal article (refereed), original research

BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility

Manjur, ABMK; Lempiäinen, JK; Malinen, M; Varjosalo, M; Palvimo, JJ; Niskanen, EA. 2021. Journal of steroid biochemistry and molecular biology. 210: 105873 A1 Journal article (refereed), original research

Chromatin-directed proteomics-identified network of endogenous androgen receptor in prostate cancer cells

Launonen, Kaisa-Mari; Paakinaho, Ville; Sigismondo, Gianluca; Malinen, Marjo; Sironen, Reijo; Hartikainen, Jaana M; Laakso, Hanna; Visakorpi, Tapio; Krijgsveld, Jeroen; Niskanen, Einari A; Palvimo, Jorma J. 2021. Oncogene. 40: 4567-4579 A1 Journal article (refereed), original research

SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites

Paakinaho, Ville; Lempiäinen, Joanna K; Sigismondo, Gianluca; Niskanen, Einari A; Malinen, Marjo; Jääskeläinen, Tiina; Varjosalo, Markku; Krijgsveld, Jeroen; Palvimo, Jorma J. 2021. Nucleic acids research. 49: 1951-1971 A1 Journal article (refereed), original research

Stress-induced nuclear condensation of NELF drives transcriptional downregulation

Rawat, Prashant; Boehning, Marc; Hummel, Barbara; Aprile-Garcia, Fernando; Pandit, Anwit S; Eisenhardt, Nathalie; Khavaran, Ashkan; Niskanen, Einari; Vos, Seychelle M; Palvimo, Jorma J; Pichler, Andrea; Cramer, Patrick; Sawarkar, Ritwick. 2021. Molecular cell. 81: 1013-1026 A1 Journal article (refereed), original research

BCOR-coupled H2A monoubiquitination represses a subset of androgen receptor target genes regulating prostate cancer proliferation

Lempiäinen, JK; Manjur, ABMK; Malinen, M; Ketola, K; Niskanen, EA; Palvimo, JJ. 2020. Oncogene. 39: 2391-2407 A1 Journal article (refereed), original research

Histonien muokkaukset ja geenien säätely

Sutinen, Siiri; Niskanen, Einari. 2020. Solubiologi. : 12-21 D1 Article in a trade journal

IRF2BP2 Modulates the Crosstalk between Glucocorticoid and TNF Signaling

Kaiser Manjur, ABM; Lempiäinen, Joanna K; Malinen, Marjo; Palvimo, Jorma J; Niskanen, Einari A. 2019. Journal of steroid biochemistry and molecular biology. 192: 105382 A1 Journal article (refereed), original research

Lack of androgen receptor SUMOylation results in male infertility due to epididymal dysfunction

Zhang, Fu-Ping; Malinen, Marjo; Mehmood, Arfa; Lehtiniemi, Tiina; Jääskeläinen, Tiina; Niskanen, Einari A; Korhonen, Hanna; Laiho, Asta; Elo, Laura L; Ohlsson, Claes; Kotaja, Noora; Poutanen, Matti; Sipilä, Petra; Palvimo, Jorma J. 2019. Nature communications. 10: 777 A1 Journal article (refereed), original research

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping

Lempiäinen Joanna K, Niskanen Einari A, Vuoti Kaisa-Mari, Lampinen Riikka E, Göös Helka, Varjosalo Markku, Palvimo Jorma J. 2017. Molecular and cellular proteomics. 16: 1462-1474 A1 Journal article (refereed), original research

Chromatin SUMOylation in heat stress : to protect, pause and organise?

Niskanen Einari A, Palvimo Jorma J. 2017. Bioessays. 39: 1600263 A1 Journal article (refereed), original research

Crosstalk between androgen and pro-inflammatory signaling remodels androgen receptor and NF-kB cistrome to reprogram the prostate cancer cell transcriptome

Malinen Marjo, Niskanen Einari A, Kaikkonen Minna U, Palvimo Jorma J. 2016. Nucleic acids research. 45: 619-630 A1 Journal article (refereed), original research

Global analysis of transcription in castration-resistant prostate cancer cells uncovers active enhancers and direct androgen receptor targets

Toropainen Sari, Niskanen Einari A, Malinen Marjo, Sutinen Päivi, Kaikkonen Minna U, Palvimo Jorma J. 2016. Scientific reports. 6: 33510 A1 Journal article (refereed), original research

Promoter-Targeted Histone Acetylation of Chromatinized Parvoviral Genome Is Essential for the Progress of Infection

Mäntylä E, Salokas K, Oittinen M, Aho V, Mäntysaari P, Palmujoki L, Kalliolinna O, Ihalainen TO, Niskanen EA, Timonen J, Viiri K, Vihinen-Ranta M. 2016. Journal of virology. 90: 4059-4066 A1 Journal article (refereed), original research

Global SUMOylation on active chromatin is an acute heat stress response restricting transcription

Niskanen Einari A, Malinen Marjo, Sutinen Päivi, Toropainen Sari, Paakinaho Ville, Vihervaara Anniina, Joutsen Jenny, Kaikkonen Minna U, Sistonen Lea, Palvimo Jorma J. 2015. Genome biology. 16: 153 A1 Journal article (refereed), original research

Reorganization of nuclear pore complexes and the lamina in late-stage parvovirus infection

Mäntylä Elina, Niskanen Einari A, Ihalainen Teemu O, Vihinen-Ranta Maija. 2015. Journal of virology. Nov 15;89: 11706-11710 A1 Journal article (refereed), original research

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Einari A. Niskanen

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Central role of SUMOylation in the regulation of chromatin interactions and transcriptional outputs of the androgen receptor in prostate cancer cells

Secreted factors from M1 macrophages drive prostate cancer stem cell plasticity by upregulating NANOG, SOX2, and CD44 through NFκB-signaling

Steroidireseptorien säätely

Chromatin accessibility and pioneer factor FOXA1 restrict glucocorticoid receptor action in prostate cancer

Complementary analysis of proteome‐wide proteomics reveals changes in RNA binding protein‐profiles during prostate cancer progression

Genetic variation is a key determinant of chromatin accessibility and drives differences in the regulatory landscape of C57BL/6J and 129S1/SvImJ mice

International Online Team-Based Learning in Higher Education of Biomedicine - Evaluation by Learning Analytics

Parvovirus nonstructural protein 2 interacts with chromatin-regulating cellular proteins

BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility

Chromatin-directed proteomics-identified network of endogenous androgen receptor in prostate cancer cells

SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites

Stress-induced nuclear condensation of NELF drives transcriptional downregulation

BCOR-coupled H2A monoubiquitination represses a subset of androgen receptor target genes regulating prostate cancer proliferation

Histonien muokkaukset ja geenien säätely

IRF2BP2 Modulates the Crosstalk between Glucocorticoid and TNF Signaling

Lack of androgen receptor SUMOylation results in male infertility due to epididymal dysfunction

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping

Chromatin SUMOylation in heat stress : to protect, pause and organise?

Crosstalk between androgen and pro-inflammatory signaling remodels androgen receptor and NF-kB cistrome to reprogram the prostate cancer cell transcriptome

Global analysis of transcription in castration-resistant prostate cancer cells uncovers active enhancers and direct androgen receptor targets

Promoter-Targeted Histone Acetylation of Chromatinized Parvoviral Genome Is Essential for the Progress of Infection

Global SUMOylation on active chromatin is an acute heat stress response restricting transcription

Reorganization of nuclear pore complexes and the lamina in late-stage parvovirus infection