Einari Niskanen - UEFConnect

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Group leader and university lecturer (bioinformatics)

Research groups

Niskanen Group: Regulatory mechanisms of steroid … 01.09.2020 -

Keywords

bioinformatics cellular stress coregulators glucocorticoid glucocorticoid receptor inflammatory response stress hormones transcription factors transcription regulation transcription repression

Publications

18 items

Complementary analysis of proteome‐wide proteomics reveals changes in RNA binding protein‐profiles during prostate cancer progression
Aikio, Erika; Koivukoski, Sonja; Kallio, Elina; Sadeesh, Nithin; Niskanen, Einari A; Latonen, Leena. 2023. Cancer reports. [First published: 17 August 2023]: 1-13
International Online Team-Based Learning in Higher Education of Biomedicine - Evaluation by Learning Analytics
Mairinoja, Laura; López-Pernas, Sonsoles; Elmoazen, Ramy; Niskanen, Einari A.; Kuningas, Tiina; Wärri, Anni; Saqr, Mohammed; Strauss, Leena. Teoksessa: Elmoazen, Ramy; López-Pernas, Sonsoles; Misiejuk, Kamila; Khalil, Mohammad; Wasson, Barbara; Saqr, Mohammed(toim.) , 2023. Proceedings of the Technology-Enhanced Learning in Laboratories Workshop (TELL 2023). s. 49-60.
Parvovirus nonstructural protein 2 interacts with chromatin-regulating cellular proteins
Mattola, Salla; Salokas, Kari; Aho, Vesa; Mäntylä, Elina; Salminen, Sami; Hakanen, Satu; Niskanen, Einari A.; Svirskaite, Julija; Ihalainen, Teemu O.; Airenne, Kari J.; Kaikkonen-Määttä, Minna; Parrish, Colin R.; Varjosalo, Markku; Vihinen-Ranta, Maija. 2022. PLoS pathogens. 18:
BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility
Manjur, ABMK; Lempiäinen, JK; Malinen, M; Varjosalo, M; Palvimo, JJ; Niskanen, EA. 2021. Journal of steroid biochemistry and molecular biology. 210: 105873
Chromatin-directed proteomics-identified network of endogenous androgen receptor in prostate cancer cells
Launonen, Kaisa-Mari; Paakinaho, Ville; Sigismondo, Gianluca; Malinen, Marjo; Sironen, Reijo; Hartikainen, Jaana M; Laakso, Hanna; Visakorpi, Tapio; Krijgsveld, Jeroen; Niskanen, Einari A; Palvimo, Jorma J. 2021. Oncogene. 40: 4567-4579
SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites
Paakinaho, Ville; Lempiäinen, Joanna K; Sigismondo, Gianluca; Niskanen, Einari A; Malinen, Marjo; Jääskeläinen, Tiina; Varjosalo, Markku; Krijgsveld, Jeroen; Palvimo, Jorma J. 2021. Nucleic acids research. 49: 1951-1971
Stress-induced nuclear condensation of NELF drives transcriptional downregulation
Rawat, Prashant; Boehning, Marc; Hummel, Barbara; Aprile-Garcia, Fernando; Pandit, Anwit S; Eisenhardt, Nathalie; Khavaran, Ashkan; Niskanen, Einari; Vos, Seychelle M; Palvimo, Jorma J; Pichler, Andrea; Cramer, Patrick; Sawarkar, Ritwick. 2021. Molecular cell. 81: 1013-1026
BCOR-coupled H2A monoubiquitination represses a subset of androgen receptor target genes regulating prostate cancer proliferation
Lempiäinen, JK; Manjur, ABMK; Malinen, M; Ketola, K; Niskanen, EA; Palvimo, JJ. 2020. Oncogene. 39: 2391-2407
Histonien muokkaukset ja geenien säätely
Sutinen, Siiri; Niskanen, Einari. 2020. Solubiologi. : 12-21
IRF2BP2 Modulates the Crosstalk between Glucocorticoid and TNF Signaling
Kaiser Manjur, ABM; Lempiäinen, Joanna K; Malinen, Marjo; Palvimo, Jorma J; Niskanen, Einari A. 2019. Journal of steroid biochemistry and molecular biology. 192: 105382
Lack of androgen receptor SUMOylation results in male infertility due to epididymal dysfunction
Zhang, Fu-Ping; Malinen, Marjo; Mehmood, Arfa; Lehtiniemi, Tiina; Jääskeläinen, Tiina; Niskanen, Einari A; Korhonen, Hanna; Laiho, Asta; Elo, Laura L; Ohlsson, Claes; Kotaja, Noora; Poutanen, Matti; Sipilä, Petra; Palvimo, Jorma J. 2019. Nature communications. 10: 777
Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping
Lempiäinen Joanna K, Niskanen Einari A, Vuoti Kaisa-Mari, Lampinen Riikka E, Göös Helka, Varjosalo Markku, Palvimo Jorma J. 2017. Molecular and cellular proteomics. 16: 1462-1474
Chromatin SUMOylation in heat stress : to protect, pause and organise?
Niskanen Einari A, Palvimo Jorma J. 2017. Bioessays. 39: 1600263
Crosstalk between androgen and pro-inflammatory signaling remodels androgen receptor and NF-kB cistrome to reprogram the prostate cancer cell transcriptome
Malinen Marjo, Niskanen Einari A, Kaikkonen Minna U, Palvimo Jorma J. 2016. Nucleic acids research. 45: 619-630
Global analysis of transcription in castration-resistant prostate cancer cells uncovers active enhancers and direct androgen receptor targets
Toropainen Sari, Niskanen Einari A, Malinen Marjo, Sutinen Päivi, Kaikkonen Minna U, Palvimo Jorma J. 2016. Scientific reports. 6: 33510
Promoter-Targeted Histone Acetylation of Chromatinized Parvoviral Genome Is Essential for the Progress of Infection
Mäntylä E, Salokas K, Oittinen M, Aho V, Mäntysaari P, Palmujoki L, Kalliolinna O, Ihalainen TO, Niskanen EA, Timonen J, Viiri K, Vihinen-Ranta M. 2016. Journal of virology. 90: 4059-4066
Global SUMOylation on active chromatin is an acute heat stress response restricting transcription
Niskanen Einari A, Malinen Marjo, Sutinen Päivi, Toropainen Sari, Paakinaho Ville, Vihervaara Anniina, Joutsen Jenny, Kaikkonen Minna U, Sistonen Lea, Palvimo Jorma J. 2015. Genome biology. 16: 153
Reorganization of nuclear pore complexes and the lamina in late-stage parvovirus infection
Mäntylä Elina, Niskanen Einari A, Ihalainen Teemu O, Vihinen-Ranta Maija. 2015. Journal of virology. Nov 15;89: 11706-11710

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Einari A. Niskanen

Research groups

Keywords

Complementary analysis of proteome‐wide proteomics reveals changes in RNA binding protein‐profiles during prostate cancer progression

International Online Team-Based Learning in Higher Education of Biomedicine - Evaluation by Learning Analytics

Parvovirus nonstructural protein 2 interacts with chromatin-regulating cellular proteins

BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility

Chromatin-directed proteomics-identified network of endogenous androgen receptor in prostate cancer cells

SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites

Stress-induced nuclear condensation of NELF drives transcriptional downregulation

BCOR-coupled H2A monoubiquitination represses a subset of androgen receptor target genes regulating prostate cancer proliferation

Histonien muokkaukset ja geenien säätely

IRF2BP2 Modulates the Crosstalk between Glucocorticoid and TNF Signaling

Lack of androgen receptor SUMOylation results in male infertility due to epididymal dysfunction

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping

Chromatin SUMOylation in heat stress : to protect, pause and organise?

Crosstalk between androgen and pro-inflammatory signaling remodels androgen receptor and NF-kB cistrome to reprogram the prostate cancer cell transcriptome

Global analysis of transcription in castration-resistant prostate cancer cells uncovers active enhancers and direct androgen receptor targets

Promoter-Targeted Histone Acetylation of Chromatinized Parvoviral Genome Is Essential for the Progress of Infection

Global SUMOylation on active chromatin is an acute heat stress response restricting transcription

Reorganization of nuclear pore complexes and the lamina in late-stage parvovirus infection