Einari Niskanen - UEFConnect

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Group leader and university lecturer (bioinformatics)

Research groups

Regulatory mechanisms of steroid receptors - Nisk… 01.09.2020 -

Keywords

bioinformatics cellular stress coregulators glucocorticoid glucocorticoid receptor inflammatory response stress hormones transcription factors transcription regulation transcription repression

Publications

16/16 items

Central role of SUMOylation in the regulation of chromatin interactions and transcriptional outputs of the androgen receptor in prostate cancer cells
Launonen, Kaisa-Mari; Varis, Vera; Aaltonen, Niina; Niskanen, Einari A; Varjosalo, Markku; Paakinaho, Ville; Palvimo, Jorma J. 2024. Nucleic acids research. [Published: 06 August 2024]:
Steroidireseptorien säätely
Paakinaho, Ville; Niskanen, Einari A. 2024. Duodecim. 140: 759-767
Chromatin accessibility and pioneer factor FOXA1 restrict glucocorticoid receptor action in prostate cancer
Helminen, Laura; Huttunen, Jasmin; Tulonen, Melina; Aaltonen, Niina; Niskanen, Einari A; Palvimo, Jorma J; Paakinaho, Ville. 2023. Nucleic acids research. 2024; 52: 625-642
Complementary analysis of proteome‐wide proteomics reveals changes in RNA binding protein‐profiles during prostate cancer progression
Aikio, Erika; Koivukoski, Sonja; Kallio, Elina; Sadeesh, Nithin; Niskanen, Einari A; Latonen, Leena. 2023. Cancer reports. 6:
Genetic variation is a key determinant of chromatin accessibility and drives differences in the regulatory landscape of C57BL/6J and 129S1/SvImJ mice
Mononen, Juho; Taipale, Mari; Malinen, Marjo; Velidendla, Bharadwaja; Niskanen, Einari; Levonen, Anna-Liisa; Ruotsalainen, Anna-Kaisa; Heikkinen, Sami. 2023. Nucleic acids research. 2024; 52: 2904-2923
International Online Team-Based Learning in Higher Education of Biomedicine - Evaluation by Learning Analytics
Mairinoja, Laura; López-Pernas, Sonsoles; Elmoazen, Ramy; Niskanen, Einari A.; Kuningas, Tiina; Wärri, Anni; Saqr, Mohammed; Strauss, Leena. Teoksessa: Elmoazen, Ramy; López-Pernas, Sonsoles; Misiejuk, Kamila; Khalil, Mohammad; Wasson, Barbara; Saqr, Mohammed(toim.) , 2023. Proceedings of the Technology-Enhanced Learning in Laboratories Workshop (TELL 2023). s. 49-60.
Parvovirus nonstructural protein 2 interacts with chromatin-regulating cellular proteins
Mattola, Salla; Salokas, Kari; Aho, Vesa; Mäntylä, Elina; Salminen, Sami; Hakanen, Satu; Niskanen, Einari A.; Svirskaite, Julija; Ihalainen, Teemu O.; Airenne, Kari J.; Kaikkonen-Määttä, Minna; Parrish, Colin R.; Varjosalo, Markku; Vihinen-Ranta, Maija. 2022. PLoS pathogens. 18:
IRF2BP2 Modulates the Crosstalk between Glucocorticoid and TNF Signaling
Kaiser Manjur, ABM; Lempiäinen, Joanna K; Malinen, Marjo; Palvimo, Jorma J; Niskanen, Einari A. 2019. Journal of steroid biochemistry and molecular biology. 192: 105382
Lack of androgen receptor SUMOylation results in male infertility due to epididymal dysfunction
Zhang, Fu-Ping; Malinen, Marjo; Mehmood, Arfa; Lehtiniemi, Tiina; Jääskeläinen, Tiina; Niskanen, Einari A; Korhonen, Hanna; Laiho, Asta; Elo, Laura L; Ohlsson, Claes; Kotaja, Noora; Poutanen, Matti; Sipilä, Petra; Palvimo, Jorma J. 2019. Nature communications. 10: 777
Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping
Lempiäinen Joanna K, Niskanen Einari A, Vuoti Kaisa-Mari, Lampinen Riikka E, Göös Helka, Varjosalo Markku, Palvimo Jorma J. 2017. Molecular and cellular proteomics. 16: 1462-1474
Chromatin SUMOylation in heat stress : to protect, pause and organise?
Niskanen Einari A, Palvimo Jorma J. 2017. Bioessays. 39: 1600263
Crosstalk between androgen and pro-inflammatory signaling remodels androgen receptor and NF-kB cistrome to reprogram the prostate cancer cell transcriptome
Malinen Marjo, Niskanen Einari A, Kaikkonen Minna U, Palvimo Jorma J. 2016. Nucleic acids research. 45: 619-630
Global analysis of transcription in castration-resistant prostate cancer cells uncovers active enhancers and direct androgen receptor targets
Toropainen Sari, Niskanen Einari A, Malinen Marjo, Sutinen Päivi, Kaikkonen Minna U, Palvimo Jorma J. 2016. Scientific reports. 6: 33510
Promoter-Targeted Histone Acetylation of Chromatinized Parvoviral Genome Is Essential for the Progress of Infection
Mäntylä E, Salokas K, Oittinen M, Aho V, Mäntysaari P, Palmujoki L, Kalliolinna O, Ihalainen TO, Niskanen EA, Timonen J, Viiri K, Vihinen-Ranta M. 2016. Journal of virology. 90: 4059-4066
Global SUMOylation on active chromatin is an acute heat stress response restricting transcription
Niskanen Einari A, Malinen Marjo, Sutinen Päivi, Toropainen Sari, Paakinaho Ville, Vihervaara Anniina, Joutsen Jenny, Kaikkonen Minna U, Sistonen Lea, Palvimo Jorma J. 2015. Genome biology. 16: 153
Reorganization of nuclear pore complexes and the lamina in late-stage parvovirus infection
Mäntylä Elina, Niskanen Einari A, Ihalainen Teemu O, Vihinen-Ranta Maija. 2015. Journal of virology. Nov 15;89: 11706-11710

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Einari A. Niskanen

Research groups

Keywords

Central role of SUMOylation in the regulation of chromatin interactions and transcriptional outputs of the androgen receptor in prostate cancer cells

Steroidireseptorien säätely

Chromatin accessibility and pioneer factor FOXA1 restrict glucocorticoid receptor action in prostate cancer

Complementary analysis of proteome‐wide proteomics reveals changes in RNA binding protein‐profiles during prostate cancer progression

Genetic variation is a key determinant of chromatin accessibility and drives differences in the regulatory landscape of C57BL/6J and 129S1/SvImJ mice

International Online Team-Based Learning in Higher Education of Biomedicine - Evaluation by Learning Analytics

Parvovirus nonstructural protein 2 interacts with chromatin-regulating cellular proteins

IRF2BP2 Modulates the Crosstalk between Glucocorticoid and TNF Signaling

Lack of androgen receptor SUMOylation results in male infertility due to epididymal dysfunction

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping

Chromatin SUMOylation in heat stress : to protect, pause and organise?

Crosstalk between androgen and pro-inflammatory signaling remodels androgen receptor and NF-kB cistrome to reprogram the prostate cancer cell transcriptome

Global analysis of transcription in castration-resistant prostate cancer cells uncovers active enhancers and direct androgen receptor targets

Promoter-Targeted Histone Acetylation of Chromatinized Parvoviral Genome Is Essential for the Progress of Infection

Global SUMOylation on active chromatin is an acute heat stress response restricting transcription

Reorganization of nuclear pore complexes and the lamina in late-stage parvovirus infection